East Prairie

Travel Guide

A tree-lined landscape with a river and fields.
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
The price is HK$737 per night from 14 Sept to 15 Sept
HK$737
HK$847 total
14 Sept - 15 Sept
includes taxes & fees
Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...
Drury Inn & Suites Sikeston, MO
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr Sikeston MO
The price is HK$513 per night from 24 Aug to 25 Aug
HK$513
HK$585 total
24 Aug - 25 Aug
includes taxes & fees
Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...
7.2/10 Good! (1,003 reviews)
"We stay here every time we are in Sikesons. Can't beat this hotel. Super clean 'comfortable!' beds, living room area, and bathrooms. Small hot breakfast. All for the best price out there. Don't skip on this hotel! Staff is always polite and helpful. We always love to walk out to the pond"

Reviewed on 20 Aug 2026

Days Inn and Suites by Wyndham Sikeston
Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

2.5 out of 5
120 S Interstate Drive Sikeston MO
The price is HK$635 per night from 23 Aug to 24 Aug
HK$635
HK$724 total
23 Aug - 24 Aug
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking and a fitness centre. Our guests praise the breakfast and the helpful staff in their reviews. ...
Best Western Plus Sikeston I-55
See all 89 properties in East Prairie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Duck Hunting, Fishing or Relaxing Family Vacation

Duck Hunting, Fishing or Relaxing Family Vacation

Hornbeak TN
Stay at this holiday home in Hornbeak. Enjoy a garden, laundry facilities and patios. Popular attractions Willow Towhead and Rat Island are located nearby.
10/10 Exceptional! (242 reviews)
"This property was one of the cleanest we have ever stayed at. They had one of the nicest coffee stations I have ever seen in a VRBO and everything you could need !"

Reviewed on 11 Aug 2026

Duck Hunting, Fishing or Relaxing Family Vacation
3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters

3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters

Hornbeak TN
Stay at this holiday home in Hornbeak. Enjoy free Wi-Fi, laundry facilities and patios. Popular attractions Willow Towhead and Rat Island are located ...
10/10 Exceptional! (11 reviews)
"Great place to stay"

Reviewed on 27 Jul 2026

3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters
Come and relax at the Refuge at beautiful Reelfoot Lake!

Come and relax at the Refuge at beautiful Reelfoot Lake!

Hornbeak TN
Enjoy free Wi-Fi, laundry facilities and patios. Popular attractions Willow Towhead and Rat Island are located nearby.
9.4/10 Exceptional! (36 reviews)
"Real foot refuge was a really nice place to stay , and they were really nice to work withWe are in Missouri, family.We had a really great time and wanting to do this again the neighbors were awesome, very friendly in kind.The real foot like visiting center.The pontoon ride was a very great experience.We ..."

Reviewed on 4 Jul 2026

Come and relax at the Refuge at beautiful Reelfoot Lake!
See all properties in East Prairie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular East Prairie attractions

Big Oak Tree State Park

8.0/10 (20 reviews)
You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.
See properties

Explore a world of travel with Expedia