Florence Vacation Homes

A cozy reading nook with a brick wall, a wooden bookshelf filled with books, a small armchair, and a framed photograph.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

In two weeks

In two months

In three months

In four months

Our top choices for Florence holiday homes

A kitchen with white cabinets, a double sink, and a window with blinds.

1. ReNew At JW's & bring your Dog too!

East Florence

Nicole L.

A living room with a blue sofa, a coffee table, a television, and a dining area with a table and chairs.

2. Pet-friendly 3-bedroom house in Florence, AL two mile from UNA!

Florence

HK$1,453 total

includes taxes & fees

13 Oct - 14 Oct

A modern kitchen with a large island, bar stools, stainless steel appliances, and a view of the outdoors.

3. Lagniappe in Florence

Florence

addie s.

HK$2,394 total

includes taxes & fees

28 Sept - 29 Sept

A white house with a covered porch, a visible door, and a window with shutters.

4. #424 DOWNTOWN FLORENCE HOME CLOSE TO EVERYTHING!

Florence

Steve-Mabel G.

HK$1,298 total

includes taxes & fees

30 Sept - 1 Oct

5. This historic home is close to everything! Walking distance to downtown Florence

Florence

HK$1,375 total

includes taxes & fees

11 Oct - 12 Oct

A living room with two sofas, a fireplace, a television, and a window with curtains.

6. The Cozy Cottage of Florence!

Florence

Sarah K.

HK$2,159 total

includes taxes & fees

6 Oct - 7 Oct

A living room with a TV mounted on the wall, a ceiling fan, a wooden floor, and a door leading to another room.

7. Charming 2-bedroom house with AC, WiFi in wonderful Florence

Florence

Jamie S.

HK$2,141 total

includes taxes & fees

13 Oct - 14 Oct

A kitchen with white cabinetry, stainless steel appliances, and a herringbone wood floor.

8. Spacious 4-bedroom house in lakefront subdivision on one and a half acres

Florence

jim l.

HK$2,864 total

includes taxes & fees

28 Sept - 29 Sept

A wooden deck with a view of a lake, a dock with a boat, and a wheelbarrow on the deck.

9. Beaver Den Rustic lake house right on shoals Creek and Wilson lake

Florence

kelly a.

HK$2,577 total

includes taxes & fees

30 Sept - 1 Oct

10. Modern Waterfront Mansion with Private Dock, kayak, paddle board and ping pong

Florence

MaryBeth P.

HK$6,213 total

includes taxes & fees

28 Sept - 29 Sept

A living room with a sectional sofa, a coffee maker, and a television.

11. 3-bedroom w/pool and all the comforts of home in Muscle Shoals-recording capital

Muscle Shoals

Tim c.

HK$2,516 total

includes taxes & fees

28 Sept - 29 Sept

A kitchen with white cabinets, a coffee maker, a bowl of coffee pods, and a window with sheer curtains.

12. Boat Parking & Shore Power, Dog-Friendly Duplex, Fenced Yard Near Pickwick Lake

Sheffield

Kristy

HK$1,601 total

includes taxes & fees

29 Sept - 30 Sept

A covered patio with two wicker chairs, a blue rug, and a potted plant.

13. The 72 Rendezvous

Cherokee

HK$2,275 total

includes taxes & fees

28 Sept - 29 Sept

A white house with a porch, surrounded by trees and a small garden.

14. Luxury Two-Home Retreat on Wilson Lake

Muscle Shoals

HK$5,520 total

includes taxes & fees

12 Oct - 13 Oct

A wooden deck with wicker furniture and a table overlooking a body of water.

15. Perfect lake front cottage! Now with stairs to the water!

Waterloo

Andrew A.

HK$2,716 total

includes taxes & fees

8 Oct - 9 Oct

A living room with a fireplace, leather sofa, television, and decorative items.

16. The Pickwick Perch | Cozy 2BD Near Lake

Counce

"The Pickwick Perch was an excellent choice for a little weekend getaway for some much needed rest and relaxation. Super cute set up with all the needed necessities. Full well equipped kitchen and dining area. The space and layout was very open and inviting. Everything was clean and tidy. The waffle towels in the bathroom were amazing and a great touch lol. It’s the small things sometimes. Very quiet and relaxing place. The host Robert was super friendly and very responsive. Overall 10/10 stay....

Sara T.

HK$1,467 total

includes taxes & fees

28 Sept - 29 Sept

A modern kitchen with dark cabinetry, stainless steel appliances, and a granite countertop.

17. Crossroads to Pickwick

Iuka

Codi J.

HK$1,789 total

includes taxes & fees

28 Sept - 29 Sept

A wooden cabin with a porch, a fire pit, and Adirondack chairs arranged around it.

18. Family & Pet Friendly Cozy Cabin 5 mins from Sportsman’s

Counce

"We use Vrbo quite frequently and we would say this is one of the best homes we've stayed at. The house was extremely well furnished and comfortable. The parking was exceptionally nice considering we were in the area for a fishing tournament and were towing boats and gear.We would definately recommend a stay here for both fishermen or families with children as the atmosphere felt very pleasant and secure."

Rebecca S.

HK$2,227 total

includes taxes & fees

28 Sept - 29 Sept

A dining area with a wooden table, clear chairs, a macrame wall hanging, and a spiral staircase.

19. McCrary Clan Lodge

Counce

Keith P.

HK$1,715 total

includes taxes & fees

3 Oct - 4 Oct

View all properties

Find holiday rentals that suit your style

Cabins

Apartments

Save an average of 15% on thousands of hotels when you're signed in

Top Florence Hotel Reviews

Residence Inn Florence Marriott

8/10 Good

"The hotel was clean and comfortable but it is near a sketchy area if you come into property the way GPS takes you. The breakfast was sufficient with eggs, bacon, waffles, oats and sausage gravy and biscuits."

Cute Home in Downtown Florence - 4 BR, 2 BA, WiFi, Pet Friendly!

10/10 Excellent

"Very easy to find the property, very easy check-in, very clean and great property to stay for any length of time. We have stayed at this property for over a month now and the property meets all of our needs and the hosts are wonderful and very accommodating. Love this property!"

Loft in the Heart of Downtown — steps away from Pickett, UNA, Dining, Shops

10/10 Excellent

"This loft is great! Just like the pictures, coazy, clean, beautiful windows with an amazing view of downtown, easy walk to all the shops and restaurants. The host was great, check and and check out were a breeze. We stayed here while moving our daughter into the dorms on campus, which is just a few minutes away. My family can't wait to stay here again when we come for football games and other visits! I have been using VRBO for years and this stands out as the best experience I have ever had! 5 stars across the board!"

Find out more about Florence