Weslaco Knapp Medical Center Hotels

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Check prices for these dates

Tonight
10 Dec - 11 Dec
Tomorrow
11 Dec - 12 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

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Our top choices for Knapp Medical Center hotels

In-room safe, desk, iron/ironing board, free cots/infant beds
Holiday Inn Express Hotel & Suites Weslaco by IHG

Holiday Inn Express Hotel & Suites Weslaco by IHG

Holiday Inn Express Hotel & Suites Weslaco by IHG
2.5 star property
2.2 km from Knapp Medical Center
9.0 out of 10, Wonderful, (884)
"It was a nice experience "
United States
Matthew
The price is HK$615
HK$694 total
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Express Hotel & Suites Weslaco by IHG
Desk, soundproofing, iron/ironing board, free cots/infant beds
Super 8 by Wyndham Weslaco

Super 8 by Wyndham Weslaco

Super 8 by Wyndham Weslaco
2.0 star property
2 km from Knapp Medical Center
8.4 out of 10, Very good, (1008)
"Was a great stay."
United States
Rafael
The price is HK$489
HK$553 total
includes taxes & fees
7 Jan - 8 Jan 2026
Super 8 by Wyndham Weslaco
Reception
Vali Ho Motel By OYO Weslaco Mercedes

Vali Ho Motel By OYO Weslaco Mercedes

Vali Ho Motel By OYO Weslaco Mercedes
2.0 star property
1 km from Knapp Medical Center
8.2 out of 10, Very good, (159)
"The shower was great. Good water pressure and plenty of heat. It was quiet and comfortable."
United States
captain
The price is HK$401
HK$508 total
includes taxes & fees
12 Dec - 13 Dec
Vali Ho Motel By OYO Weslaco Mercedes
Room amenity
Express Inn

Express Inn

Express Inn
2.0 star property
2 km from Knapp Medical Center
6.2 out of 10, (392)
"It was an ok room but the restroom ceiling did had water damages and holes."
United States
Joanna
The price is HK$471
HK$533 total
includes taxes & fees
14 Dec - 15 Dec
Express Inn
Outdoor pool
Weslaco Inn by Capital O Near Mercedes

Weslaco Inn by Capital O Near Mercedes

Weslaco Inn by Capital O Near Mercedes
2.0 star property
1.4 km from Knapp Medical Center
8.2 out of 10, Very good, (575)
"Clean rooms, very nice staff. "
United States
Laura
The price is HK$449
HK$508 total
includes taxes & fees
29 Dec - 30 Dec
Weslaco Inn by Capital O Near Mercedes
Exterior
Hampton Inn Weslaco

Hampton Inn Weslaco

Hampton Inn Weslaco
2.5 star property
4.1 km from Knapp Medical Center
9.2 out of 10, Wonderful, (598)
"Always nice to stay when visiting family"
United States
Jorge
The price is HK$697
HK$788 total
includes taxes & fees
21 Dec - 22 Dec
Hampton Inn Weslaco
Desk, laptop workspace, blackout curtains, iron/ironing board
Best Western Town Center Inn

Best Western Town Center Inn

Best Western Town Center Inn
2.5 star property
3.8 km from Knapp Medical Center
8.6 out of 10, Excellent, (952)
"The staff was great and my stay was very relaxing."
United States
Sheila
The price is HK$610
HK$689 total
includes taxes & fees
20 Dec - 21 Dec
Best Western Town Center Inn
Lobby
Motel 6 Weslaco, TX

Motel 6 Weslaco, TX

Motel 6 Weslaco, TX
2.0 star property
3.3 km from Knapp Medical Center
8.4 out of 10, Very good, (1002)
"Todo excelente "
Mexico
Joel
The price is HK$476
HK$538 total
includes taxes & fees
6 Jan - 7 Jan 2026
Motel 6 Weslaco, TX
Exterior
Texas Inn Donna

Texas Inn Donna

Texas Inn Donna
2.5 star property
6.9 km from Knapp Medical Center
8.8 out of 10, Excellent, (153)
"Clean had all we needed nice place to stay"
United States
Sandy
The price is HK$488
HK$552 total
includes taxes & fees
11 Jan - 12 Jan 2026
Texas Inn Donna
Ballroom
Victoria Palms Inn & Suites

Victoria Palms Inn & Suites

Victoria Palms Inn & Suites
2.5 star property
5.3 km from Knapp Medical Center
8.4 out of 10, Very good, (1003)
"everything was excellent "
United States
Emma
The price is HK$529
HK$598 total
includes taxes & fees
1 Jan - 2 Jan 2026
Victoria Palms Inn & Suites
Lobby
La Quinta Inn & Suites by Wyndham Mercedes Outlet Mall

La Quinta Inn & Suites by Wyndham Mercedes Outlet Mall

La Quinta Inn & Suites by Wyndham Mercedes Outlet Mall
3.0 star property
9.8 km from Knapp Medical Center
9.2 out of 10, Wonderful, (1002)
"YES, the room was spotless and the staff courteous."
United States
Kenneth
The price is HK$678
HK$766 total
includes taxes & fees
14 Dec - 15 Dec
La Quinta Inn & Suites by Wyndham Mercedes Outlet Mall
Exterior
Comfort Inn & Suites Donna near I-2

Comfort Inn & Suites Donna near I-2

Comfort Inn & Suites Donna near I-2
2.5 star property
8.7 km from Knapp Medical Center
8.8 out of 10, Excellent, (597)
"We enjoyed our stay"
United States
Gloria
The price is HK$545
HK$616 total
includes taxes & fees
11 Jan - 12 Jan 2026
Comfort Inn & Suites Donna near I-2
Desk, laptop workspace, blackout curtains, free WiFi
Texas Inn Weslaco

Texas Inn Weslaco

Texas Inn Weslaco
2.0 star property
3.3 km from Knapp Medical Center
7.2 out of 10, Good, (223)
"."
Mexico
EBNHER
Texas Inn Weslaco
Lobby
Quality Inn & Suites at The Outlets Mercedes/Weslaco

Quality Inn & Suites at The Outlets Mercedes/Weslaco

Quality Inn & Suites at The Outlets Mercedes/Weslaco
2.5 star property
8.7 km from Knapp Medical Center
8.2 out of 10, Very good, (1002)
"Good ppace tomstay and great location next to outlets for shopping "
United States
Gustavo
The price is HK$550
HK$622 total
includes taxes & fees
7 Jan - 8 Jan 2026
Quality Inn & Suites at The Outlets Mercedes/Weslaco
Exterior
Home2 Suites By Hilton San Juan

Home2 Suites By Hilton San Juan

Home2 Suites By Hilton San Juan
3.0 star property
16.7 km from Knapp Medical Center
9.6 out of 10, Exceptional, (446)
"Great hotel to stay when you’re in the Valley "
United States
Carlos
The price is HK$647
HK$718 total
includes taxes & fees
8 Jan - 9 Jan 2026
Home2 Suites By Hilton San Juan
Outdoor pool
Texas Inn La Feria

Texas Inn La Feria

Texas Inn La Feria
2.0 star property
15.5 km from Knapp Medical Center
6.8 out of 10, (88)
"Affordable & clean"
United States
aurelio
Texas Inn La Feria
Lobby
Rodeway Inn San Juan

Rodeway Inn San Juan

Rodeway Inn San Juan
2.0 star property
18.5 km from Knapp Medical Center
8.4 out of 10, Very good, (666)
"Great welcoming staff."
United States
Violetta
The price is HK$385
HK$427 total
includes taxes & fees
21 Dec - 22 Dec
Rodeway Inn San Juan
Outdoor pool
Texas Inn Alamo

Texas Inn Alamo

Texas Inn Alamo
2.5 star property
15.1 km from Knapp Medical Center
7.4 out of 10, Good, (370)
"Room was roomy and clean staff not too considerate about my room request but i like the rooms "
United States
Marisela
Texas Inn Alamo
Exterior
La Copa Inn

La Copa Inn

La Copa Inn
2.5 star property
13.8 km from Knapp Medical Center
7.0 out of 10, Good, (90)
"The continental breakfast was included by rate, so it was not available "
Mexico
Adolfo David Castillo
The price is HK$549
HK$621 total
includes taxes & fees
21 Dec - 22 Dec
La Copa Inn
Exterior
La Quinta Inn & Suites by Wyndham Alamo - McAllen East

La Quinta Inn & Suites by Wyndham Alamo - McAllen East

La Quinta Inn & Suites by Wyndham Alamo - McAllen East
3.0 star property
15.3 km from Knapp Medical Center
8.4 out of 10, Very good, (1001)
"Convenient location and clean."
United States
Erika
The price is HK$585
HK$661 total
includes taxes & fees
11 Jan - 12 Jan 2026
La Quinta Inn & Suites by Wyndham Alamo - McAllen East
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Knapp Medical Center Hotel Reviews

Home2 Suites By Hilton San Juan

Home2 Suites By Hilton San Juan

10/10 Excellent
"Clean, very spacious rooms, bathroom clean and big. It has a little kitchen, smart tv, sofa, bid fridge, tea table, desk, everything you could expect from a hotel."
Sea Lim 1-night trip
Posted 2 days ago
Home2 Suites By Hilton San Juan

Hotels near other Knapp Medical Center attractions

A Spicebush Swallowtail in Rio Grande Valley State Park, Texas

Valley Nature Center

4.0/5 (21 reviews)
Enjoy an outing to Valley Nature Center during your stay in Weslaco. Visit the shops in this family-friendly area or simply enjoy its restaurants.
See properties
Awesome scenery!
Photo by Jesús Rangel Mendez
Open Photo by Jesús Rangel Mendez

Estero Llano Grande State Park

4.2/5 (10 reviews)
You can take time to visit Estero Llano Grande State Park during your travels to Weslaco. Visit the shops in this family-friendly area or simply enjoy its restaurants.
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Frequently asked questions

What's the area like around Knapp Medical Center?
Knapp Medical Center is located in a budget-friendly area of Weslaco that travellers like for its cathedral. If you're looking for a convenient place to stay, take a look at the 16 hotels and other accommodation options you'll find within a mile.
What's the best place to stay close to Knapp Medical Center?
Located a short 0.6 mi (1 km) from Knapp Medical Center, Vali Ho Motel By OYO Weslaco Mercedes is one of the top choices for your stay based on our traveller data. Another good option is Weslaco Inn, located just 0.9 mi (1.4 km) away.
How many hotels should I expect to find near Knapp Medical Center?
Expedia has 16 hotels and other accommodation options within a mile from Knapp Medical Center.
If I need to cancel the hotel reservation for my stay near Knapp Medical Center, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your arrival date. If your reservation is non-refundable, it might still be possible to cancel it and receive a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to review top deals close to Knapp Medical Center.

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