Best Matthews Hotels in 2026 from HK$421 - Fully Refundable Options

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in Matthews

Pet friendly

Apartment

Pool

Condo

Family friendly

Waterpark

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Matthews hotels

A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.

A Hampton Inn hotel with a modern facade, a stone entrance, and a well-lit entrance area.

A hotel lobby with a bar area, seating arrangements, and a large window providing natural light.

An indoor swimming pool with lounge chairs, a lifeguard stand, and large windows offering a view of the outside.

1. Hampton Inn Sikeston

Sikeston

John

HK$823

HK$932 total

includes taxes & fees

4 Oct - 5 Oct

A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.

A reception area with a reception desk, a large wall-mounted sign, and a potted plant.

A buffet with various food items, including omelets and baked goods, served in metal containers.

A kitchenette with a coffee machine, a kettle, and storage shelves.

2. Holiday Inn Express & Suites Sikeston Southwest by IHG

Sikeston

Melissa

HK$730

HK$826 total

includes taxes & fees

4 Oct - 5 Oct

An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.

An outdoor bar area with a modern design, featuring a counter, seating, and a view of the interior.

A modern indoor swimming pool with clear glass walls, a tiled deck, and multiple lounge chairs.

A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.

3. Fairfield Inn & Suites by Marriott Sikeston

Sikeston

Allen

HK$792

HK$897 total

includes taxes & fees

11 Oct - 12 Oct

An outdoor bar area with a modern design, featuring a counter, bar stools, and a seating area with chairs.

A modern hotel room with a large window, a gray sofa, a small round table, a white chair, and a bed.

A modern hotel with a sign reading "Towneplace Suites by Marriott Fairfield." It features a flat roof, large windows, and a well-lit entrance.

4. TownePlace Suites by Marriott Sikeston

Sikeston

Stacy

HK$824

HK$933 total

includes taxes & fees

18 Oct - 19 Oct

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.

A spacious lobby with a polished floor, seating areas, and modern lighting fixtures.

An outdoor seating area with sofas and planters, surrounded by a building with large windows and a brick wall.

5. Drury Inn & Suites Sikeston, MO

Sikeston

Scott

HK$737

HK$848 total

includes taxes & fees

29 Oct - 30 Oct

A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.

A reception area with a wooden reception desk, a large painting on the wall, and a potted plant.

An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows providing natural light.

6. Best Western Plus Sikeston I-55

Sikeston

Shelley

HK$659

HK$751 total

includes taxes & fees

1 Oct - 2 Oct

A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.

A modern kitchen with stainless steel appliances, wooden cabinets, and a bright yellow accent wall.

A living room with a sofa, two chairs, a coffee table, a television, and a window with blinds.

A Travel Inn and Suites with a brick facade, a flat roof, and a welcoming entrance.

7. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Sikeston

Craig

HK$545

HK$621 total

includes taxes & fees

8 Oct - 9 Oct

A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.

A spacious lobby with a central atrium, a piano, and a reception desk.

A Days Inn hotel with a brick facade, large windows, and a sign above the entrance.

8. Days Inn and Suites by Wyndham Sikeston

Sikeston

David

HK$520

HK$593 total

includes taxes & fees

8 Oct - 9 Oct

A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.

A motel with a covered entrance, multiple rooms, and a parking lot.

A hotel kitchen with a long counter, various appliances, and a tiled backsplash.

A hotel room with two beds, a sofa, a coffee table, and artwork on the walls.

9. Super 8 by Wyndham Sikeston/Miner Area

Sikeston

William

HK$448

HK$511 total

includes taxes & fees

13 Oct - 14 Oct

A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.

A hot tub area with a tiled floor, a wooden deck surrounding the tub, and a view of the sky through large windows.

A living room with two sofas, a coffee table, a TV, and a cabinet.

A hotel room with a bed, a desk with a TV, a chair, a bathroom with a bathtub, and a window with curtains.

10. Comfort Inn & Suites Sikeston I-55

Sikeston

Starlette

HK$679

HK$773 total

includes taxes & fees

29 Oct - 30 Oct

A hotel room with two beds, a desk, a chair, a TV, and a mirror.

A bathroom with a bathtub, toilet, and shower curtain.

A reception area with a counter, a coffee machine, and seating.

A motel with a blue awning and a green 7-Eleven. It has a covered parking area and a two-story structure with a balcony.

11. Country Yard Inn and Suite

Sikeston

William

HK$481

HK$572 total

includes taxes & fees

3 Oct - 4 Oct

A modern hotel room with a large bed, bedside tables, a nightstand, a wall-mounted lamp, a window with a view of a road, and a wall-mounted air conditioner.

A hotel with a central entrance, multiple parking spaces, and a well-lit facade.

A modern kitchen with a stone backsplash, a dining area with red chairs, and a red accent wall with a framed picture.

A room with a brown leather sofa, a red chair, and a cityscape painting on the wall.

12. Super 8 By Wyndham Marston

Marston

Brenda

HK$438

HK$500 total

includes taxes & fees

1 Oct - 2 Oct

A building with a fountain and flower beds in front.

A hotel room with a large bed, two bedside tables with lamps, a chair, a small table, and a picture on the wall.

A hotel room with a beige sofa, two patterned armchairs, a ceiling fan, a flat-screen TV, and a window with curtains.

A modern kitchen with dark wooden cabinets, a central island, and a ceiling fan.

13. The Riverstone Hotel Charleston-Sikeston

Charleston

Kathleen

HK$522

HK$579 total

includes taxes & fees

3 Oct - 4 Oct

A hotel room with two beds, a television, a desk, and a mirror.

A hotel room with a bed, a desk, a television, and a seating area with a small table.

A bathroom with a sink, mirror, and chair.

A reception area with a counter, a refrigerator stocked with beverages, a no smoking sign, and a window with an American flag.

14. Travel Inn Marston I-55 by Hotel O

Marston

Frank

HK$350

HK$421 total

includes taxes & fees

2 Oct - 3 Oct

A hotel room with a bed, a desk, a chair, a bathroom with a bathtub, and a patterned floor.

A hotel with a brick facade, multiple windows, and a covered entrance area.

A living room with a sofa, a coffee table, a clock, and a painting on the wall.

A hotel reception area with a reception desk, framed certificates, and a painting on the wall.

15. Econo Lodge Dexter

Dexter

Herman

HK$400

HK$449 total

includes taxes & fees

29 Oct - 30 Oct

A diner with booth seating, a checkered floor, and a counter with a cash register.

A gym with multiple exercise machines, a clock on the wall, and a window with blinds.

A reception area with a marble counter, potted plants, a clock, and a TV on the wall.

A lobby with a round rug, two potted plants, three framed artworks, and two black leather chairs.

16. Travelodge by Wyndham Dexter

Dexter

Steven

HK$716

HK$804 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a large bed, a desk, a television, and a bathroom visible through an open door.

A bathroom with a sink, mirror, towel rack, shower, and toilet.

A motel with a sign reading "Eagle Inn" and a parking lot with several cars.

A hotel room with two beds, a nightstand, a lamp, and a window with curtains.

17. Eagle Inn Charleston

Charleston

Jackson

HK$518

HK$575 total

includes taxes & fees

1 Oct - 2 Oct

A modern hotel lobby with a bar area, seating, and artwork on the walls.

A modern kitchen with a large island, bar stools, wine bottles, and a built-in TV.

A swimming pool with clear blue water, surrounded by sun loungers and a lifeguard stand.

A modern hotel with a prominent sign, a covered entrance, and a well-lit exterior.

18. Hampton Inn By Hilton Dexter

Dexter

Kendall

HK$766

HK$860 total

includes taxes & fees

11 Oct - 12 Oct

A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.

A restaurant with wooden cabinets, a refrigerator, and a counter with various items. There are tables and chairs for dining.

A reception area with a counter, a flat-screen TV, and a window with blinds.

19. Super 8 by Wyndham Charleston/Sikeston East MO

Charleston

William

HK$467

HK$518 total

includes taxes & fees

1 Oct - 2 Oct

A coffee shop with a coffee machine, espresso cups, a sink, and a trash bin.

A hotel room with two beds, a desk with a lamp, a chair, a dresser, and a door with a handle.

A hotel lobby with a reception desk, a waiting area with a sofa and armchairs, and a patterned carpet.

A hotel hallway with patterned carpet, light green walls, and a ceiling with recessed lighting.

20. Dexter Inn

Dexter

Edward

HK$541

HK$608 total

includes taxes & fees

8 Oct - 9 Oct

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Top Matthews Hotel Reviews

Holiday Inn Express & Suites Sikeston Southwest by IHG

10/10 Excellent

"Everything"

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

8/10 Good

"NA NA NA NA NA NA NA NA NA NA NA NA NA"

Super 8 By Wyndham Marston

8/10 Good

"Very clean and a very friendly staff! Air conditioner in room wasn’t working perfectly so it felt very humid but overall was not bad. I would stay here again!"

Hampton Inn Sikeston

10/10 Excellent

"Staff was great"

Days Inn and Suites by Wyndham Sikeston

10/10 Excellent

"This was a very good value. It has been the best hotel I've stayed at in awhile."

TownePlace Suites by Marriott Sikeston

10/10 Excellent

"My overall experience was amazing from the time I checked in until I left. The staff were super pleasant and incredible. My room was clean and spacious. I never been in an extended stay room before. I definitely will be booking a suite like this one again."

More cheap stays in Matthews

Super 8 by Wyndham Sikeston/Miner Area

2609 E Malone Ave Sikeston MO

HK$448

HK$511 total

13 Oct - 14 Oct

includes taxes & fees

Super 8 by Wyndham Charleston/Sikeston East MO

310 S Story St Charleston MO

HK$467

HK$518 total

1 Oct - 2 Oct

includes taxes & fees

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO

HK$520

HK$593 total

8 Oct - 9 Oct

includes taxes & fees

Best Western Plus Sikeston I-55

120 S Interstate Drive Sikeston MO

HK$659

HK$751 total

1 Oct - 2 Oct

includes taxes & fees

Holiday Inn Express & Suites Sikeston Southwest by IHG

115 Hospitality Dr Sikeston MO

HK$730

HK$826 total

4 Oct - 5 Oct

includes taxes & fees

8.8/10 Excellent! (513 reviews)

Hampton Inn Sikeston

1240 Commerce Drive Sikeston MO

HK$823

HK$932 total

4 Oct - 5 Oct

includes taxes & fees

9/10 Wonderful! (624 reviews)

Frequently asked questions

Where is the best place for a stay in Matthews?

Drury Inn & Suites Sikeston, MO, located 9.7 mi (15.5 km) from the heart of Matthews, is a top choice for your stay, based on our traveller data. Other good choices for your trip to the area are Days Inn and Suites by Wyndham Sikeston and Best Western Plus Sikeston I-55. See all available top hotels, or vacation rentals in Matthews.

What are some of the best holiday rentals that Matthews has to offer?

Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy: This holiday home rental outside of Matthews offers a fireplace, a balcony and a BBQ to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. You can relax into your holiday with a garden and a selection of games. See all vacation rentals in Matthews.

If I need to cancel my hotel reservation in Matthews, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable if cancelled prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Matthews.

How is it to stay in Matthews?

Travellers to Matthews will find plenty to explore and enjoy. There are 42 hotels and other accommodation options in the surrounding area. Find out more about Matthews.

What are the top places to visit in Matthews?

Places to visit in the wider area include Marston Community Center, Big Oak Tree State Park and Sikeston Depot Museum. You'll also find New Madrid Historical Museum and Central Park in the area. Take a look at what more there is to see and do in Expedia's Matthews guide.

What's the seasonal weather in Matthews?

The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Matthews is 1533 mm.

Matthews hotels from HK$421

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Matthews

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Matthews hotels

1. Hampton Inn Sikeston

2. Holiday Inn Express & Suites Sikeston Southwest by IHG

3. Fairfield Inn & Suites by Marriott Sikeston

4. TownePlace Suites by Marriott Sikeston

5. Drury Inn & Suites Sikeston, MO

6. Best Western Plus Sikeston I-55

7. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

8. Days Inn and Suites by Wyndham Sikeston

9. Super 8 by Wyndham Sikeston/Miner Area

10. Comfort Inn & Suites Sikeston I-55

11. Country Yard Inn and Suite

12. Super 8 By Wyndham Marston

13. The Riverstone Hotel Charleston-Sikeston

14. Travel Inn Marston I-55 by Hotel O

15. Econo Lodge Dexter

16. Travelodge by Wyndham Dexter

17. Eagle Inn Charleston

18. Hampton Inn By Hilton Dexter

19. Super 8 by Wyndham Charleston/Sikeston East MO

20. Dexter Inn

Top Matthews Hotel Reviews

Holiday Inn Express & Suites Sikeston Southwest by IHG

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Super 8 By Wyndham Marston

Hampton Inn Sikeston

Days Inn and Suites by Wyndham Sikeston

TownePlace Suites by Marriott Sikeston

More cheap stays in Matthews

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Charleston/Sikeston East MO

Days Inn and Suites by Wyndham Sikeston

Best Western Plus Sikeston I-55

Holiday Inn Express & Suites Sikeston Southwest by IHG

Hampton Inn Sikeston

Frequently asked questions

Explore a world of travel with Expedia

Go further with the Expedia app