
Medical Center District hotels in San Antonio
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Medical Center District hotels

Fairfield Inn & Suites by Marriott San Antonio Medical Center
Fairfield Inn & Suites by Marriott San Antonio Medical CenterMedical Center District
9.0 out of 10, Wonderful, (1,004 reviews)
The price is HK$649
HK$757 total
includes taxes & fees
26 Feb - 27 Feb

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NWMedical Center District
8.4 out of 10, Very good, (3,205 reviews)
The price is HK$694
HK$820 total
includes taxes & fees
23 Feb - 24 Feb

San Antonio Marriott Northwest Medical Center
San Antonio Marriott Northwest Medical CenterMedical Center District
8.6 out of 10, Excellent, (1,018 reviews)
The price is HK$790
HK$939 total
includes taxes & fees
28 Feb - 1 Mar

Courtyard by Marriott Medical Center San Antonio
Courtyard by Marriott Medical Center San AntonioMedical Center District
8.8 out of 10, Excellent, (1,003 reviews)
The price is HK$696
HK$822 total
includes taxes & fees
1 Mar - 2 Mar

Drury Inn & Suites San Antonio Northwest Medical Center
Drury Inn & Suites San Antonio Northwest Medical CenterMedical Center District
9.2 out of 10, Wonderful, (1,280 reviews)
The price is HK$703
HK$831 total
includes taxes & fees
1 Mar - 2 Mar

Studio 6 San Antonio, Tx - Northwest Medical Center
Studio 6 San Antonio, Tx - Northwest Medical CenterMedical Center District
7.4 out of 10, Good, (248 reviews)
The price is HK$395
HK$462 total
includes taxes & fees
23 Feb - 24 Feb

Country Inn & Suites by Radisson, San Antonio Medical Center, TX
Country Inn & Suites by Radisson, San Antonio Medical Center, TXMedical Center District
6.8 out of 10, (1,001 reviews)
The price is HK$475
HK$554 total
includes taxes & fees
22 Mar - 23 Mar

Studio 6 San Antonio, TX - Medical Center
Studio 6 San Antonio, TX - Medical CenterMedical Center District
6.8 out of 10, (829 reviews)
The price is HK$398
HK$487 total
includes taxes & fees
23 Feb - 24 Feb

Park Inn by Radisson
Park Inn by RadissonMedical Center District
7.2 out of 10, Good, (1,002 reviews)
The price is HK$499
HK$583 total
includes taxes & fees
22 Mar - 23 Mar

OYO Inn & Suites Medical Center San Antonio
OYO Inn & Suites Medical Center San AntonioMedical Center District
7.2 out of 10, Good, (228 reviews)
The price is HK$422
HK$547 total
includes taxes & fees
23 Feb - 24 Feb

Motel 6 San Antonio, TX - Northwest Medical Center
Motel 6 San Antonio, TX - Northwest Medical CenterMedical Center District
6.0 out of 10, (1,001 reviews)
The price is HK$408
HK$483 total
includes taxes & fees
23 Feb - 24 Feb

Flex Studios
Flex StudiosMedical Center District
6.0 out of 10, (508 reviews)
The price is HK$340
HK$402 total
includes taxes & fees
23 Feb - 24 Feb

La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB
La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB9 km from Medical Center District
9.2 out of 10, Wonderful, (1,152 reviews)
The price is HK$640
HK$747 total
includes taxes & fees
1 Mar - 2 Mar

Ramada by Wyndham San Antonio Near SeaWorld/Lackland AFB
Ramada by Wyndham San Antonio Near SeaWorld/Lackland AFB7.7 km from Medical Center District
8.4 out of 10, Very good, (1,004 reviews)
The price is HK$511
HK$597 total
includes taxes & fees
1 Mar - 2 Mar

Hyatt Vacation Club at Wild Oak Ranch, San Antonio
Hyatt Vacation Club at Wild Oak Ranch, San AntonioFar West Side, 11.3 km from Medical Center District
9.0 out of 10, Wonderful, (1,461 reviews)
The price is HK$649
HK$1,091 total
includes taxes & fees
1 Mar - 2 Mar

Courtyard by Marriott San Antonio SeaWorld - Westover Hills
Courtyard by Marriott San Antonio SeaWorld - Westover HillsFar West Side, 12.1 km from Medical Center District
8.6 out of 10, Excellent, (1,136 reviews)
The price is HK$790
HK$939 total
includes taxes & fees
26 Feb - 27 Feb

Hilton San Antonio Hill Country
Hilton San Antonio Hill CountryFar West Side, 11.6 km from Medical Center District
8.4 out of 10, Very good, (1,069 reviews)
The price is HK$692
HK$1,127 total
includes taxes & fees
1 Mar - 2 Mar

Holiday Inn San Antonio Seaworld by IHG
Holiday Inn San Antonio Seaworld by IHGFar West Side, 11.9 km from Medical Center District
8.6 out of 10, Excellent, (1,004 reviews)
The price is HK$713
HK$842 total
includes taxes & fees
26 Feb - 27 Feb

Best Western near Lackland AFB/SeaWorld
Best Western near Lackland AFB/SeaWorldFar West Side, 6.9 km from Medical Center District
8.0 out of 10, Very good, (1,203 reviews)
The price is HK$438
HK$511 total
includes taxes & fees
23 Feb - 24 Feb
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels in Medical Center District
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
![]() Fairfield Inn & Suites by Marriott San Antonio Medical Center | 9.0 Wonderful 1,004 reviews | View | ||||||
![]() Drury Inn & Suites San Antonio Northwest Medical Center | 9.2 Wonderful 1,280 reviews | View | ||||||
![]() San Antonio Marriott Northwest Medical Center | 8.6 Excellent 1,018 reviews | View | ||||||
![]() Courtyard by Marriott Medical Center San Antonio | 8.8 Excellent 1,003 reviews | View | ||||||
![]() La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW | 8.4 Very good 3,205 reviews | View |
Where to stay in Medical Center District
Find the best Medical Center District areas for the activities you enjoy most. Learn more about Medical Center District
Learn more about Medical Center District

Downtown San Antonio
Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

Photo by Sarah C.
Open Photo by Sarah C.
Uptown
If you're spending some time in Uptown, San Antonio Zoo and Aquarium and Marion Koogler McNay Art Museum are top sights worth seeing.

Far West Side
While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Fort Sam Houston
You'll love the stunning river views in Fort Sam Houston, and you might want to stick around to check out United States Army Medical Department Museum, a top place to visit.

Arena District
If you're spending some time in Arena District, Frost Bank Center and Freeman Coliseum are top sights worth seeing.
Top Medical Center District Hotel Reviews

San Antonio Marriott Northwest Medical Center
10/10 Excellent























































































