Otay Mesa hotels in San Diego
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Our top choices for Otay Mesa hotels
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHGOtay Mesa
8.2 out of 10, Very good, (1,691 reviews)
"Everything was excellent. Very courteous staff. I plan to stay here again when I visit San Diego in the spring."
Sue
The price is HK$862
HK$980 total
includes taxes & fees
19 Apr - 20 Apr
Quality Suites San Diego Otay Mesa
Quality Suites San Diego Otay MesaOtay Mesa
7.0 out of 10, Good, (1,012 reviews)
"The only hotel in otay mesa and overall the service was good"
MARIA
The price is HK$776
HK$882 total
includes taxes & fees
10 May - 11 May
Best Western Americana Inn
Best Western Americana Inn8 km from Otay Mesa
9.0 out of 10, Wonderful, (1,261 reviews)
"Super nice, rooms were nice and clean and breakfast was good. There was even homemade salsa."
Patricia
The price is HK$958
HK$1,090 total
includes taxes & fees
5 May - 6 May
Studio 6 Suites San Ysidro, CA -San Diego South Bay
Studio 6 Suites San Ysidro, CA -San Diego South Bay6.9 km from Otay Mesa
8.0 out of 10, Very good, (1,597 reviews)
"Very nice. Beds wete a but hard but very clean and nice facilities pool looked very clean"
Nancy
The price is HK$588
HK$669 total
includes taxes & fees
16 Apr - 17 Apr
Holiday Inn Express San Diego South - Chula Vista by IHG
Holiday Inn Express San Diego South - Chula Vista by IHG14.5 km from Otay Mesa
9.4 out of 10, Exceptional, (1,092 reviews)
"Everything was excellent! The staff was very friendly and helpful! We loved the breakfast set up! If we are ever in the area, we will definitely stay here again!"
ron
The price is HK$1,052
HK$1,157 total
includes taxes & fees
26 Apr - 27 Apr
Valli Hi Motel
Valli Hi Motel7.9 km from Otay Mesa
8.4 out of 10, Very good, (1,011 reviews)
"Close to the cbx boarder crossing which is why we stayed there. Rooms were clean and spacious with a small refrigerator and microwave. Short walk to a McDonald’s!"
donald
The price is HK$545
HK$621 total
includes taxes & fees
27 Apr - 28 Apr
Sycuan Casino Resort
Sycuan Casino Resort28.5 km from Otay Mesa
9.4 out of 10, Exceptional, (1,852 reviews)
"Staff is welcoming and so helpful. Room was very clean, spacious, and the bed was comfortable. The casino downstairs had 3 restaurants and 2 corner delis so getting food was not a problem. Will be coming back."
Maria
The price is HK$972
HK$1,163 total
includes taxes & fees
19 Apr - 20 Apr
Hampton Inn & Suites Imperial Beach San Diego
Hampton Inn & Suites Imperial Beach San Diego13.7 km from Otay Mesa
9.4 out of 10, Exceptional, (1,013 reviews)
"Room was great, very clean. Staff was so friendly and helpful. Other visitors were great conversation over breakfast. Tons of places to eat walking distance and super close to the beach. For the price it was incredible. Will be returning soon. "
Isabel
The price is HK$1,121
HK$1,280 total
includes taxes & fees
10 May - 11 May
SpringHill Suites by Marriott Chula Vista Eastlake
SpringHill Suites by Marriott Chula Vista Eastlake10.5 km from Otay Mesa
9.6 out of 10, Exceptional, (627 reviews)
"The pool was closed during my stay, but outside seating was comfortable. Breakfast was good with many options. The room was clean and comfortable."
Amy
The price is HK$1,473
HK$1,623 total
includes taxes & fees
3 May - 4 May
Lafayette Hotel & Club
Lafayette Hotel & Club26.8 km from Otay Mesa
9.2 out of 10, Wonderful, (1,590 reviews)
"This hotel is one of a kind. The pool area is stunning. Restaurants are great. Hip, busy scene at the bars and restaurants, yet quiet and cozy in your stylish room. The design of everything is over the top-- it was a treat to stay here. We'll be back."
Kelly
The price is HK$1,950
HK$2,241 total
includes taxes & fees
14 May - 15 May
Comfort Inn Chula Vista San Diego South
Comfort Inn Chula Vista San Diego South13 km from Otay Mesa
8.2 out of 10, Very good, (1,426 reviews)
"Front desk personnel were very friendly. Check process was smooth and fast. Breakfast was ok, the served Mexican "
Mary
The price is HK$839
HK$925 total
includes taxes & fees
26 Apr - 27 Apr
Motel 6 El Cajon, CA - San Diego
Motel 6 El Cajon, CA - San Diego27 km from Otay Mesa
7.4 out of 10, Good, (1,641 reviews)
"The staff is always polite. Always friendly and welcoming. Way different place to visit then it was years ago. It's clean and pleasant. "
wes
The price is HK$576
HK$634 total
includes taxes & fees
10 May - 11 May
Best Western Chula Vista/Otay Valley Hotel
Best Western Chula Vista/Otay Valley Hotel7.1 km from Otay Mesa
8.0 out of 10, Very good, (1,692 reviews)
"It was peaceful, clean, convenient and the staff was very friendly "
Jennifer
The price is HK$859
HK$945 total
includes taxes & fees
26 Apr - 27 Apr
Best Western Plus Marina Gateway Hotel
Best Western Plus Marina Gateway Hotel16.9 km from Otay Mesa
9.2 out of 10, Wonderful, (3,777 reviews)
"Helpful, courteous staff. The suites include 2 queen beds plus a sofa bed perfect for our family. The location is right off the freeway and near many places to eat. "
Sonia
The price is HK$1,192
HK$1,313 total
includes taxes & fees
26 Apr - 27 Apr
Sheraton San Diego Resort
Sheraton San Diego Resort28.1 km from Otay Mesa
8.4 out of 10, Very good, (3,460 reviews)
"Wow! I am so happy we got to stay here. Everything about this place was luxury- while still keeping it at a good budget. The bike rentals were super fun and the staff was AMAZING! Great place to stay! :)"
Mary
The price is HK$1,269
HK$1,855 total
includes taxes & fees
29 Apr - 30 Apr
La Quinta Inn by Wyndham San Diego Chula Vista
La Quinta Inn by Wyndham San Diego Chula Vista12.9 km from Otay Mesa
8.6 out of 10, Excellent, (1,586 reviews)
"The room was nice and clean. The staff was very friendly. Our needs were met. As a landmark, they are located adjacent/behind Denny's. Google Maps sent us around through the back which was the long way."
Rachel
The price is HK$792
HK$872 total
includes taxes & fees
26 Apr - 27 Apr
Holiday Inn Express San Diego Airport - Old Town by IHG
Holiday Inn Express San Diego Airport - Old Town by IHG28.8 km from Otay Mesa
9.2 out of 10, Wonderful, (1,072 reviews)
"Great people. Right next to the freeway, but the back side at least is relatively quiet. Walking distance to old town."
Kevin
The price is HK$1,105
HK$1,270 total
includes taxes & fees
27 Apr - 28 Apr
Days Inn by Wyndham San Diego-East/El Cajon
Days Inn by Wyndham San Diego-East/El Cajon27.3 km from Otay Mesa
7.6 out of 10, Good, (1,002 reviews)
"My room was perfect in every way. The complimentary breakfast was excellent, plenty of variety and quantity with nice seating.
Day’s Inn has a great location for traveling on foot, bus or trolley to many locations.
I will stay here again on my next trip. "
Marla
The price is HK$726
HK$800 total
includes taxes & fees
19 Apr - 20 Apr
Wyndham Garden San Diego Near SeaWorld
Wyndham Garden San Diego Near SeaWorld31.3 km from Otay Mesa
7.4 out of 10, Good, (4,253 reviews)
"We stayed one night due to a delayed flight. The place was clean & tidy, the pool was fantastic. Staff was amazing. Great for a short budget friendly stay. "
Karla
The price is HK$886
HK$1,018 total
includes taxes & fees
26 Apr - 27 Apr
Hampton Inn & Suites San Diego Airport Liberty Station
Hampton Inn & Suites San Diego Airport Liberty Station29.2 km from Otay Mesa
9.2 out of 10, Wonderful, (1,701 reviews)
"Very friendly staff helped me when I needed a little help with small things. I needed a place to rest and everyone was most kind."
Denise
The price is HK$1,303
HK$1,498 total
includes taxes & fees
26 Apr - 27 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Otay Mesa
Find the best Otay Mesa areas for the activities you enjoy most. Learn more about Otay Mesa
Learn more about Otay Mesa
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Pacific Beach
Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.
Mission Beach
If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.
Gaslamp Quarter
San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.
Ocean Beach
Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Dog Beach and Sunset Cliffs Natural Park.
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