Panama City Spa Hotel

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Our top choices for Panama City hotels with a spa

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
Tocumen
8.6 out of 10, Excellent, (1855)
"Better than expected: Location, transportation to and from airport, pool area tropical and comfortable. "
United States
Marty
The price is HK$973
HK$1,070 total
includes taxes & fees
29 Dec - 30 Dec
Riande Aeropuerto Hotel & Casino

Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (562)
"Amazing hotel , location , staff and amenities . Clean, elegant , great service. "
United States
Nicole
The price is HK$2,975
HK$3,272 total
includes taxes & fees
12 Jan - 13 Jan 2026
Sofitel Legend Casco Viejo, Panama City

Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
4.5 star property
Casco Viejo
9.8 out of 10, Exceptional, (258)
"Great location!"
United States
Erik
The price is HK$3,022
HK$3,324 total
includes taxes & fees
5 Jan - 6 Jan 2026
Hotel La Compañía Casco Antiguo

The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
5.0 star property
Veracruz
8.0 out of 10, Very good, (1004)
"Great place and location, excellent food choices! "
United States
Francisco
The price is HK$1,773
HK$1,951 total
includes taxes & fees
8 Jan - 9 Jan 2026
The Westin Playa Bonita Panama

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (643)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is HK$1,803
HK$1,983 total
includes taxes & fees
4 Jan - 5 Jan 2026
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Waldorf Astoria Panama

Waldorf Astoria Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1002)
"I loved everything about my stay "
United States
Stephanie
The price is HK$1,716
HK$1,887 total
includes taxes & fees
10 Jan - 11 Jan 2026
Waldorf Astoria Panama

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (994)
"Was amazing food was delicious and stay was great "
United States
Amanda
The price is HK$1,043
HK$1,147 total
includes taxes & fees
9 Jan - 10 Jan 2026
Sheraton Grand Panama

W Panama

W Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1001)
"Great vibes"
United States
Ashley
The price is HK$1,612
HK$1,773 total
includes taxes & fees
3 Jan - 4 Jan 2026
W Panama

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2140)
"Great location of the hotel with a lovely breakfast and friendly staff"
United States
fouad
The price is HK$840
HK$924 total
includes taxes & fees
16 Jan - 17 Jan 2026
Plaza Paitilla Inn Hotel

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
Casco Viejo
9.2 out of 10, Wonderful, (1001)
"Nice hotel in the historic center, excellent location for sightseeing and walking around at night."
United States
Antonio
The price is HK$2,241
HK$2,465 total
includes taxes & fees
25 Dec - 26 Dec
Central Hotel Panama Casco Viejo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Panama City

Top Panama City attractions for a relaxing vacation

Panama City is a vibrant hub offering a unique blend of urban excitement and lush natural beauty, perfect for travellers seeking spa hotels. Start your journey at the serene Parque Metropolitano, where you can immerse yourself in nature with trails that lead to breathtaking views of the city skyline—ideal for a morning jog or a peaceful stroll before indulging in a spa treatment. Next, explore the historical Casco Viejo, a UNESCO World Heritage site, where cobblestone streets are lined with charming cafés and boutique shops, providing a lovely backdrop for leisurely afternoons. Don’t miss the Biomuseo, an architectural marvel designed by Frank Gehry, showcasing Panama’s rich biodiversity; a visit here can be paired with a rejuvenating spa experience at a nearby hotel. For a taste of local culture, the Mercado de Mariscos offers fresh seafood delicacies—consider a relaxing dinner followed by a detoxifying spa session back at your hotel. Finally, a short trip to the Panama Canal will leave you in awe of this engineering marvel; many hotels in the area offer spa packages that include canal tours, providing the perfect blend of relaxation and adventure. Staying in the upscale Punta Pacifica neighbourhood places you near luxury hotels that feature exceptional spa services, ensuring you feel pampered after a day of exploration.

Find the best hotels & resorts with spas in Panama City

For those seeking relaxation and rejuvenation in Panama City, these hotels offer outstanding spa facilities and well-being amenities. Each hotel provides travelers with serene environments and luxurious treatments.

Ramada Plaza By Wyndham Panama Punta Pacífica

  • Why it's great for tailored spa getaway: With a stellar review rating of 9.6, Ramada Plaza By Wyndham Panama Punta Pacífica is perfect for travelers who appreciate spa treatments in elegant surroundings. The hotel features treatment rooms that cater to relaxation and wellness, making it a top choice for spa aficionados.
  • Other amenities: This hotel offers a variety of luxuries including an outdoor pool, complimentary breakfast, and a fully equipped fitness centre. Guests can enjoy the convenience of onsite shopping, a terrace, and a concierge service, ensuring a comfortable and fulfilling stay.
  • Neighborhood: San Francisco
  • Nearby attractions: Calle 50 - 0.7 km, Multiplaza Pacific Mall - 0.3 km, ATLAPA Conventions Center - 1 km

Plaza Paitilla Inn Hotel

  • Why it's great for tailored spa getaway: Plaza Paitilla Inn Hotel is a sanctuary for spa lovers, with a wide array of treatments including hot stone massages and reflexology in its onsite spa. With an impressive traveler review rating of 9.4, it ensures an exceptional experience for those looking to unwind and rejuvenate.
  • Other amenities: Alongside its spa offerings, travelers can enjoy an outdoor pool, free buffet breakfast, and secure valet parking. The hotel features a terrace, billiards, and a snack bar for leisurely breaks. With air conditioning and daily housekeeping, every stay is made comfortable and convenient.
  • Neighborhood: Punta Paitilla
  • Nearby attractions: Avenida Balboa - 0.5 km, Cinta Costera - 0.8 km, Multicentro Panama - 1.4 km

The Executive Hotel

  • Why it's great for tailored spa getaway: Why it’s great: The Executive Hotel stands out with an excellent guest review rating of 9.2, offering a delightful spa experience with its steam room. This hotel caters to travelers looking to rejuvenate and relax, making it an ideal choice for spa aficionados. Its inviting atmosphere ensures guests feel welcomed and pampered throughout their stay.
  • Other amenities:
  • Other amenities: The hotel features an outdoor pool with sun umbrellas for lounging, along with complimentary breakfast options to start the day. Guests can take advantage of airport transportation services, self-parking, and concierge assistance. The hotel also offers a terrace for enjoying the warm weather, fitness facilities for an active lifestyle, and housekeeping services for a pristine environment.
  • Neighborhood: Bella Vista
  • Nearby attractions: Uruguay Street - 0.6 km, Calle 50 - 0.7 km, Avenida Balboa - 0.8 km

Hotel Riu Plaza Panama

  • Why it's great for tailored spa getaway: The Hotel Riu Plaza Panama is an ideal retreat for spa enthusiasts, featuring a dedicated spa with treatment rooms and accessible facilities. With a remarkable traveler review rating of 9.0, travelers can indulge in a range of spa services designed to promote relaxation and well-being.
  • Other amenities: Guests will appreciate the outdoor pool, complimentary buffet breakfast, and valet parking. The hotel also offers a fitness centre, terrace, and onsite shopping options. With a relaxing garden and a poolside bar, every corner provides a tranquil escape from the bustling city atmosphere.
  • Neighborhood: Bella Vista
  • Nearby attractions: Uruguay Street - 1.5 km, Calle 50 - 0 km, Via Espana - 1 km

Hotel Riu Plaza Panama

  • Why it's great for tailored spa getaway: The Hotel Riu Plaza Panama stands out as a premier choice for spa enthusiasts, offering a top spa with accessible treatment rooms and a guest review rating of 9.0. Travelers can indulge in a variety of treatments designed to pamper and rejuvenate, making it an ideal retreat after a day exploring the city.
  • Other amenities: Guests can enjoy a range of features including a stunning outdoor pool, complimentary buffet breakfast, and a well-equipped fitness centre. The hotel also offers valet parking, a terrace for relaxation, and an onsite shopping area for added convenience. Additional perks include a private hot tub and a concierge service to assist with local attractions.
  • Neighborhood: Bella Vista
  • Nearby attractions: Uruguay Street - 1.5 km, Calle 50 - 0 km, Via Espana - 1 km

Top Panama City Hotel Reviews

Frequently asked questions

Looking to holiday at a spa hotel in Panama City?
Forget the stress of everyday life and book yourself a hotel with a spa. Travellers highly recommend Panama City for its array of shops and gourmet restaurants—your day tour starts here. Make sure you enjoy the cafes during your stay. Spa hotels are a great way to take a break from your routine and add a layer of luxury to your holiday.
What is the best spa hotel in Panama City?
Megapolis Hotel Panamá is a top luxury spa hotel featuring 3 bars, a casino, a shopping centre and a rooftop terrace. Enjoy a facial, body scrub or detox wrap at the on-site spa. Other popular spa hotels in Panama City include Las Americas Golden Tower Panama and W Panama.
How many spa hotels are there in Panama City?
Expedia has 24 spa hotels to choose from in Panama City.
What's there to see and do in Panama City?
Enjoy Panama City with a stop at Albrook Shopping Mall, Via Espana and Iglesia del Carmen. If you have a little extra time during your trip, you might want to check out Uruguay Street and Crown Casino.
What is a Panama City spa hotel?
Spa hotels in Panama City have full on-site spas and offer services including facials and a choice of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation and relaxation.

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