Poplar Bluff Vacation Homes

A sunset over a calm lake with red autumn leaves on the right.

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Our top choices for Poplar Bluff holiday homes

A house with a front porch decorated with hay bales, a scarecrow, and pumpkins.

1. Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff

Poplar Bluff

Anonymous traveller

HK$2,229 total

includes taxes & fees

24 Sept - 25 Sept

A wooden deck with steps leading to a house, surrounded by trees.

2. Get Away Acres 1/2 mile off highway 60 extra sanitized

Ellsinore

Anonymous traveller

HK$1,028 total

includes taxes & fees

24 Sept - 25 Sept

A kitchen with wooden cabinets, a stainless steel refrigerator, a stove, and a window.

3. Hunting / Fishing Cabin at Lake Wappapello

Williamsville

HK$1,957 total

includes taxes & fees

24 Sept - 25 Sept

A two-story house with a front porch, a covered entryway, and a small garden with white flowers.

4. Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy

Dexter

Tammy G.

HK$1,685 total

includes taxes & fees

27 Sept - 28 Sept

A cozy living room with two leather sofas, a stone wall, wooden ceiling, and a large sliding glass door leading to an outdoor deck.

5. Doc's Cottage - A-Frame in Piggott, AR

Piggott

Mary C.

HK$1,853 total

includes taxes & fees

24 Sept - 25 Sept

A modern kitchen with white cabinets, a marble island, and stainless steel appliances.

6. Scotty's sunny spot

Doniphan

Mickey S.

HK$2,994 total

includes taxes & fees

24 Sept - 25 Sept

A modern kitchen with stainless steel appliances, wooden cabinets, and a white countertop.

7. The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MO

Dexter

HK$1,261 total

includes taxes & fees

27 Sept - 28 Sept

A modern kitchen with a central island, bar stools, stainless steel appliances, and wooden flooring.

8. The Morning Glory - Country Cottage

Piggott

Justin C.

HK$2,023 total

includes taxes & fees

27 Sept - 28 Sept

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Top Poplar Bluff Hotel Reviews

Drury Inn & Suites Poplar Bluff

10/10 Excellent

"Clean room, staff"

Home Sweet Home, Spacious Sunroom & Fun Deck!

10/10 Excellent

"We really enjoyed our stay in this home. The kitchen was so well equipped with everything that you could ever hope for. My granddaughter has stayed in several Vrbo and has never seen a kitchen so well equipped. We really enjoyed the sun room and deck. The property is central located for easy access to the surrounding town. I would definitely rent this home again."

Find out more about Poplar Bluff