San Francisco Hotels: 2026 Top 10 San Francisco Hotels with Limited-Time Deals @Expedia

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Property	Property class	Guest rating
Aloft by Marriott Panama	3.5 star property	8.8 Excellent 1,001 reviews	View
Plaza Paitilla Inn Hotel	3.5 star property	9.4 Exceptional 2,220 reviews	View
Courtyard by Marriott Panama Multiplaza Mall	4.0 star property	9.0 Wonderful 1,009 reviews	View
Sheraton Grand Panama	4.0 star property	8.6 Excellent 1,004 reviews	View
Decapolis Hotel Panama City	4.0 star property	8.6 Excellent 1,716 reviews	View

Where to stay in San Francisco

Find the best San Francisco areas for the activities you enjoy most.

A coastal cityscape with buildings, a hill with a church, and a clear blue sky.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

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A spiraling skyscraper against a clear blue sky.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

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A city skyline with modern high-rise buildings and a river in the foreground.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

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A cityscape at sunset with tall buildings silhouetted against the sky.

Punta Paitilla

Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Pacific Center while you're in town.

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A coastal cityscape with high-rise buildings, a calm sea, and a rocky shoreline.

Calidonia

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Via Espana.

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Top San Francisco Hotel Reviews

Sheraton Grand Panama

10/10 Excellent

"Overall experience was great. Restaurant opitions in the hotel are super, bar is top notch. If I had to mention something not 100% was the bed, but I would give it an 8 out of 10. Overall 5 stars."

Principe Hotel and Suites

8/10 Good

"My stay was great! The only suggestion Id give would be to shampoo the seating downstairs and in the rooms a bit...Outside of that I can honestly say they've done a great job maintaining the property, good beds, good customer service , beautiful rooms ,great prices,location and clean rooms! Thank you guys!"

Las Americas Golden Tower Panama

10/10 Excellent

"Tuve una muy buena experiencia. El lugar estaba limpio, bien ubicado y el personal fue muy amable y atento durante toda la estancia. El proceso de check-in fue rápido y todo funcionó tal como se esperaba. Sin duda volvería a hospedarme aquí y lo recomendaría a quienes busquen una opción cómoda, con buen servicio y una excelente relación calidad-precio."

Central Hotel Panama Casco Viejo

8/10 Good

"The hotel's location is excellent, right in the heart of the lively Casco Viejo district. Museums, restaurants, shops, and the waterfront are all within easy walking distance. There was always something happening in the square across from the hotel entrance, from live music to graduation celebrations and photography sessions, making the area feel vibrant and full of energy. The breakfast staff were outstanding—friendly, attentive, and very accommodating. The breakfast buffet offered a wide variety of options, including fresh fruit, juices, and a made-to-order omelet station, making it a great way to start the day. The biggest drawback, and the reason I would hesitate to stay here again, was the noise. The rooms offer very little sound insulation. We could clearly hear full conversations from the room next door, and children were running through the hallways well past midnight. The rooms also overlook an atrium where music played late into the evening. Unfortunately, what surprised us most was being awakened at 2:00 a.m. by hotel staff vacuuming. The vacuum ran for about 30 minutes, and it was loud enough that I checked the clock because I couldn't believe housekeeping was vacuuming in the middle of the night. If you're looking for a hotel in the center of all the action, the location and service are excellent. However, if you're a light sleeper or value a quiet night's rest, you may want to consider choosing a different property."

Decapolis Hotel Panama City

10/10 Excellent

"Our stay at Decapolis Hotel was absolutely amazing from start to finish. The hotel is modern, clean, and in a fantastic location with easy access to restaurants, shopping, and attractions. The rooms were spacious, comfortable, and always kept spotless by the housekeeping staff. What really made our stay memorable was the outstanding customer service. Every member of staff we encountered was friendly, professional, and eager to help. They made us feel welcome from the moment we checked in until the day we left. The amenities were excellent, and the overall atmosphere made it easy to relax after a day of exploring Panama. I would definitely stay here again and highly recommend Decapolis Hotel to anyone looking for a comfortable, high-quality hotel with exceptional service.Unfortunately, our experience at Petit Bistro was extremely disappointing. The restaurant brought me the wrong meal. Mistakes happen, and I completely understand that kitchens can get busy. However, instead of acknowledging the mistake, the staff repeatedly insisted that I had ordered the wrong dish, even though the food they served did not match the menu description or what I had ordered before. This made me feel as though I didn't understand the menu, rather than simply admitting there had been an error. Only later did they apologize, explaining that the kitchen was very busy and had made a mistake. By that point, I had already paid for the incorrect meal and left."

Frequently asked questions

What is San Francisco like?

San Francisco is a welcoming neighbourhood that travellers like for its restaurants. Make sure that you visit Multiplaza Pacific Mall and Calle 50 as part of your San Francisco travel plans.

Where is the best hotel for a stay in San Francisco?

Based on our traveller data, Megapolis Hotel Panamá is one of the top choices for your stay in San Francisco. This hotel is steps from Avenida Balboa, and offers a full-service spa and a casino. Other good choices for your stay in the area include Courtyard by Marriott Panama Multiplaza Mall and Aloft by Marriott Panama.

How many hotels can I expect to find in San Francisco?

If you're searching for places to stay in Panama City, Expedia has something to meet your needs with 326 San Francisco hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in San Francisco, will I receive a refund?

Yes! Most hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to view the best deals in San Francisco.

What is there to do in this Panama City neighbourhood?

While you're in San Francisco, a shopping trip to Multiplaza Pacific Mall, Pacific Center or Avenida Balboa might be the perfect way to find that souvenir you've been looking for. Calle 50 and Via Espana are some other stops worth a visit in the neighbourhood. A few places to visit in the area around San Francisco include Panama Canal Murals, Colonial Religious Art Museum and Bingo 90. When you're sightseeing in Panama City, Soho City Center and National Shrine of the Heart of Mary are also worth a stop.

San Francisco hotels in Panama City

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Our top choices for San Francisco hotels

1. Ramada Plaza by Wyndham Panama Punta Pacifica

2. Courtyard by Marriott Panama Multiplaza Mall

3. Sheraton Grand Panama

4. Aloft by Marriott Panama

5. Plaza Paitilla Inn Hotel

6. Residence Inn by Marriott Panama City

7. JW Marriott Panama

8. Las Americas Golden Tower Panama

9. San Francisco by Wynwood House

10. Megapolis Hotel Panamá

11. Decapolis Hotel Panama City

12. Dovle Residences by HMS-Preferred Member

13. Boutique Apartments Panamá Coco del Mar

14. Modern Apartments PH Living 73 SF

15. Modern Apartments at the Hub City views

16. Boutique Apartments Atlapa

17. w Engaging 1BR w Balcony in San Francisco

18. Casa Orquídea

19. Wanders Panama by Boutique Apartments

20. Luxury Apartment in the Panamá City

Compare popular hotels in San Francisco

Where to stay in San Francisco

Casco Viejo

Bella Vista

El Cangrejo

Punta Paitilla

Calidonia

Top San Francisco Hotel Reviews

Sheraton Grand Panama

Frequently asked questions