San Francisco

Panama City

The Bridge of the Americas in summer, Panama City
The Bridge of the Americas in summer, Panama City
This great beach is not far from the Royal Decameron Panama - and it is usually deserted!
La entrada a la Ciudad de Panamá
Edificio el tornillo

Popular places to visit

Things to do


Top hotels in San Francisco

Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
The price is HK$1,047 per night from 3 Apr to 4 Apr
HK$1,047
HK$1,151 total
3 Apr - 4 Apr
includes taxes & fees
Stay at this spa resort in Panama City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.6/10 Excellent! (1,004 reviews)
Nice convenient placed hotel. Pleasant and very helpful staff. Lovely comfortable place to stay

Reviewed on 4 Mar 2026

Sheraton Grand Panama
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
The price is HK$1,292 per night from 1 Apr to 2 Apr
HK$1,292
HK$1,421 total
1 Apr - 2 Apr
includes taxes & fees
Stay at this spa hotel in Panama City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the breakfast and the helpful staff in their ...
9/10 Wonderful! (1,007 reviews)
Shops like malls were nearby and food places. The hotel overall is nice, but it seemed as if they rushed to prepare my room and certain things seemed not so clean. I also did not really enjoy the food there

Reviewed on 4 Mar 2026

Las Americas Golden Tower Panama
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica Panama City Panama
The price is HK$1,785 per night from 5 Apr to 6 Apr
HK$1,785
HK$1,963 total
5 Apr - 6 Apr
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free Wi-Fi, 4 outdoor pools and 3 restaurants. Our guests praise the helpful staff in their reviews. Popular ...
9/10 Wonderful! (1,002 reviews)
Highly recommended

Reviewed on 3 Mar 2026

JW Marriott Panama
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

4 out of 5
Via Israel Multiplaza Pacific Mall Panama City Panama
The price is HK$922 per night from 28 Mar to 29 Mar
HK$922
HK$1,014 total
28 Mar - 29 Mar
includes taxes & fees
Stay at this business-friendly hotel in Panama City. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff in their reviews. ...
9/10 Wonderful! (1,012 reviews)
Great location and service.

Reviewed on 4 Mar 2026

Courtyard by Marriott Panama Multiplaza Mall
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Avenida Balboa Con Multicentro Panama City Panama
The price is HK$1,085 per night from 6 Mar to 7 Mar
HK$1,085
HK$1,194 total
6 Mar - 7 Mar
includes taxes & fees
Stay at this spa hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free valet parking. Our guests praise the breakfast and the helpful staff in their ...
8.6/10 Excellent! (1,587 reviews)
I didn’t get no ocean view this time

Reviewed on 3 Mar 2026

Decapolis Hotel Panama City
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

3.5 out of 5
Italy Avenue, Punta Paitilla Panama City Panama
The price is HK$843 per night from 26 Mar to 27 Mar
HK$843
HK$927 total
26 Mar - 27 Mar
includes taxes & fees
Stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the pool in their ...
9.4/10 Exceptional! (2,140 reviews)
Everything is always great: friendly, clean, big TV with lots of channels, quiet, modern and the best breakfast in the city.

Reviewed on 3 Mar 2026

Plaza Paitilla Inn Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around San Francisco

Aerial cityscape skyline of Panama City

Obarrio

Unique features of Obarrio include the casinos and coffee shops. Make a stop by Calle 50 or Soho City Center while you're exploring the area.

Obarrio
Panama, Panama City

Punta Pacifica

Notable for its seaside views, restaurants and casinos, Punta Pacifica is a sought-after destination for many travellers visiting Panama City. If you want to see some sights in the area, check out Avenida Balboa or Multiplaza Pacific Mall.

Punta Pacifica
 sunset sky above Panama City -  cityscape panorama view

Punta Paitilla

Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Multicentro Panama while you're in town.

Punta Paitilla
Summer time in Panama City, blue sky and sunny days to enjoy this city. #lifeatexpedia #PanamaCity #travel

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Crown Casino.

Bella Vista
Aerial view of the city skyline of Panama City business district

Campo Alegre

3.5/5(5 area reviews)

If you're spending some time in Campo Alegre, Uruguay Street and Calle 50 are top sights worth seeing.

Campo Alegre
Old and traditional Yatch Club at Cinta Costera, Panama City, Panama.

Marbella

You'll enjoy the restaurants and parks in Marbella. You might want to make time for a stop at Avenida Balboa or Cinta Costera.

Marbella


San Francisco