Hotels in Santa Cruz

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Our top choices for Santa Cruz hotels

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (346)
"Wonderful staff with beautiful pool area and amenities. Great restaurant too."
Canada
Jay
The price is HK$1,019
HK$1,019 total
9 Jan - 10 Jan 2026
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (211)
"Great hotel, food and location albeit a little expensive "
United States
Reinaldo
The price is HK$865
HK$865 total
20 Dec - 21 Dec
Marriott Santa Cruz de la Sierra Hotel

Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra
3.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (74)
"Great Spot"
United States
Jose
The price is HK$296
HK$296 total
24 Dec - 25 Dec
Ibis Santa Cruz DE LA Sierra

Camino Real Hotel

Camino Real Hotel
4.5 star property
Santa Cruz
8.8 out of 10, Excellent, (407)
"The parrots. Unique"
United States
Juan P
The price is HK$1,401
HK$1,401 total
25 Dec - 26 Dec
Camino Real Hotel

Sun Hotel

Sun Hotel
3.5 star property
Santa Cruz
8.4 out of 10, Very good, (330)
"Staff spoke English. Airport pickup beat any US hotel. Rooms nice. Restaurant was ok"
United States
Peter
The price is HK$697
HK$697 total
12 Dec - 13 Dec
Sun Hotel

Hotel Cortez

Hotel Cortez
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (122)
"The staff and property are second to none! "
United States
Cynthia
The price is HK$953
HK$953 total
14 Dec - 15 Dec
Hotel Cortez

HOTEL OSHO

HOTEL OSHO
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (34)
"Hot tub worked well and room was very comfortable! 24 hr market across the street came in handy. The best hotel I've stayed at in Bolivia!"
United States
Robert
HOTEL OSHO

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (253)
"Nice hotel "
United States
Narciso Lorenzo
The price is HK$498
HK$498 total
15 Dec - 16 Dec
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (93)
"Come and go easily, intellectual and kind owners who are working hard to make the property improvements that will bring this hotel up to the next level. A family friendly environment with easy walking distance to everything you need. Bed was not the best, but I know they are upgrading so I appreciate the ongoing process. For a few nights stay, the deals are very fair prices. "
United States
Andrew
Apart Hotel Premium Suites Santa Cruz

Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra
5.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (103)
"Great location and very clean hotel. Will stay again soon."
United States
William
The price is HK$778
HK$778 total
4 Jan - 5 Jan 2026
Novotel Santa Cruz De La Sierra

TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz
4.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (145)
"Nice stay with good service "
United States
Jianyuan
The price is HK$770
HK$770 total
14 Dec - 15 Dec
TRYP by Wyndham Santa Cruz

Chairú Eco Hotel

Chairú Eco Hotel
3.5 star property
Santa Cruz
9.6 out of 10, Exceptional, (47)
"Nice property. Would definitely stay there again and again. Only negative was on our last night there was a really noisy party next door that lasted until 2am. "
United States
Andrew
Chairú Eco Hotel

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (81)
"Good price, great hotel!"
United States
James
The price is HK$303
HK$303 total
12 Dec - 13 Dec
Premium Suites Deluxe Aparthotel Equipetrol

Delfines Collection Hotel By Mercure

Delfines Collection Hotel By Mercure
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (71)
"Clean comfortable rooms "
United States
mary
The price is HK$316
HK$316 total
14 Dec - 15 Dec
Delfines Collection Hotel By Mercure

Swissôtel Santa Cruz De La Sierra

Swissôtel Santa Cruz De La Sierra
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (81)
"Beautiful hotel"
Australia
Joanna
The price is HK$1,152
HK$1,152 total
1 Jan - 2 Jan 2026
Swissôtel Santa Cruz De La Sierra

Lido Hotel

Lido Hotel
3.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (30)
"Very helpful and nice staff. Quiet location. near the central plaza. Great value "
United Kingdom
David
The price is HK$355
HK$355 total
14 Dec - 15 Dec
Lido Hotel

Alfonsina Hotel Boutique by Inboccaluppo

Alfonsina Hotel Boutique by Inboccaluppo
3.5 star property
Santa Cruz
9.4 out of 10, Exceptional, (40)
"Love it. Will stay again!!"
United States
Juan
The price is HK$825
HK$825 total
1 Jan - 2 Jan 2026
Alfonsina Hotel Boutique by Inboccaluppo

Hotel LP Santa Cruz Centro

Hotel LP Santa Cruz Centro
3.0 star property
Santa Cruz
8.0 out of 10, Very good, (280)
"Clean, friendly staff"
United States
Giovanna
Hotel LP Santa Cruz Centro

Hotel LP Equipetrol

Hotel LP Equipetrol
3.5 star property
Santa Cruz
8.2 out of 10, Very good, (201)
"Nice place to stay"
United States
Ricardo
Hotel LP Equipetrol

Hotel Las Américas

Hotel Las Américas
3.0 star property
Santa Cruz
6.0 out of 10, (1)
"O chuveiro foi impossível tomar um.banho de qualidade "
Brazil
Jean
The price is HK$299
HK$299 total
14 Dec - 15 Dec
Hotel Las Américas
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Top Santa Cruz Hotel Reviews

Guide to exploring Santa Cruz

Top reasons to visit Santa Cruz

  • Bustling Markets: Experience the vibrant local life by exploring Santa Cruz's lively markets, filled with fresh produce, handicrafts, and local delicacies.
  • Cultural Attractions: Discover stunning cathedrals and notable landmarks that reflect the rich history and culture of the region.
  • Outdoor Adventures: Venture into nearby Amboró National Park for breathtaking natural beauty and exciting outdoor activities.
  • Thrilling Sports: Enjoy the electrifying atmosphere of local soccer matches, a beloved pastime in Santa Cruz.
  • Diverse Accommodation: Choose from a wide range of hotels and hostels that cater to every traveller's needs and budget.

Find great hotels in Santa Cruz

Discover a diverse array of hotel accommodation options in Santa Cruz, Bolivia, designed to meet the needs of every traveller. Whether you seek a comfortable family stay, a pet-friendly getaway, or a business-friendly environment, you’ll find hotels and hostels that cater to your requirements. Enjoy accessible hotels and convenient lodging in this vibrant city, ensuring a memorable experience tailored to your journey.

  • Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel: Nestled in the heart of Santa Cruz, Los Tajibos offers a harmonious blend of comfort and sophistication. This 3.5-star hotel provides a welcoming atmosphere for both business and family travellers. With amenities tailored for children, including a First Aid Kit, families can enjoy peace of mind during their stay. Its elegant design and attentive service make it an ideal choice for those seeking a balanced vacation experience, whether for work or leisure.
  • Hotel G: For pet lovers, Hotel G stands out as a 3.5-star retreat that welcomes your furry companions. This hotel’s pet-friendly policies ensure that both you and your pets can enjoy a relaxing getaway without leaving them behind. Located conveniently within Santa Cruz, the property allows dogs and cats, making it perfect for travellers who wish to explore the city with their beloved pets. The warm and inviting atmosphere combined with personalised service creates a memorable stay for all guests.
  • Marriott Santa Cruz de la Sierra Hotel: Experience luxury at its finest at the 5-star Marriott Santa Cruz de la Sierra. This hotel is designed for those seeking a spa-themed family retreat, complete with a full-service spa and pool. Children are well catered for with complimentary cribs available. Guests can unwind under pool umbrellas or indulge in rejuvenating spa treatments, including massages, ensuring a truly relaxing experience. The exquisite facilities paired with exceptional service make this hotel a premier choice for discerning travellers.

Where to stay in Santa Cruz

Santa Cruz, Bolivia, offers a vibrant blend of culture and adventure, making it an ideal destination for families and solo travellers alike. Explore the bustling city streets, relax in tropical surroundings, or venture to nearby attractions like the Amboró National Park. With a range of accommodation options to suit all budgets, you'll find a welcoming atmosphere filled with friendly locals. Experience the diverse vibes of this active city at a comfortable altitude, perfect for excursions and relaxation.

  • Florida Province: Nestled in the beautiful Santa Cruz region, Florida Province is renowned for its stunning outdoor experiences and diverse landscapes. The area offers a variety of hiking trails that lead to breathtaking mountains and waterfalls, making it an ideal destination for adventure seekers. The province experiences a moderate influx of tourists, particularly from January to February and July, allowing visitors to enjoy its natural splendour during peak seasons. With its national parks and scenic vistas, Florida Province is perfect for those looking to immerse themselves in nature and engage in outdoor activities.
  • Camiri: Located in the heart of Santa Cruz, Camiri is a vibrant city that showcases Bolivian culture and adventure. This captivating city attracts visitors year-round, with peaks in January, July, and September. Camiri is famed for its rich cultural experiences, offering various monuments and lookout points that provide stunning views of the surrounding landscape. The lively piazza square serves as a hub for local events and socialising, making it a delightful spot to absorb the local atmosphere. Whether you’re after cultural exploration or thrilling outdoor activities, Camiri is sure to impress.
  • Andrés Ibáñez Province: Situated within the Santa Cruz department, Andrés Ibáñez Province is a treasure trove for outdoor enthusiasts and nature lovers. The province sees a steady stream of visitors throughout the year, with peak seasons in March and from September to October. Here, you can explore lush rainforests and national state parks, perfect for hiking and discovering diverse wildlife. The mountainous terrain and relaxing resorts provide ample opportunities for adventure and relaxation alike, making Andrés Ibáñez a must-visit for an unforgettable holiday experience.

Things to do in Santa Cruz

Santa Cruz, Bolivia, is a vibrant destination perfect for culture enthusiasts, families, and city explorers. Visitors can immerse themselves in local life at bustling markets, enjoy thrilling soccer matches, or experience the elegance of opera performances. For adventure seekers, Santa Cruz offers a variety of tours and activities that showcase the region's natural beauty and excitement, making it an ideal spot for unforgettable adventures.

Shopping

In Santa Cruz, visit Ventura Mall for a vibrant shopping experience with a mix of entertainment and family-friendly options. Don't miss La Recova Artisan Walk for unique local crafts and souvenirs. For a stylish atmosphere, check out Patio Design LifeStyle Center, perfect for family outings and shopping.

Recreation

Ramon Tahuichi Aguilera Stadium offers an energetic atmosphere, perfect for sports enthusiasts. Engage in recreational activities, enjoy local matches, and soak up the vibrant culture of Santa Cruz. This venue provides an excellent opportunity to witness the passion for sports in Bolivia.

Adventure

Explore the beautiful Amboró National Park, renowned for its rich biodiversity and stunning landscapes, perfect for hiking and wildlife spotting. For an adrenaline rush, try paragliding over the picturesque valleys, offering breathtaking views of the region's natural beauty. Don't miss the vibrant local markets for a cultural adventure.

Nightlife

In Santa Cruz, the Cine Center offers a delightful cinematic experience, perfect for a romantic evening or family outing. For a cultural night, the Casa Municipal de Cultura Raúl Otero Reiche presents captivating theatre performances, bringing entertainment and romance to the heart of the city.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Santa Cruz

To save money during your visit to Santa Cruz, consider travelling in January, June, or August when accommodation prices are lower. Saturdays are your best bet for cheaper stays, while Tuesdays are the priciest. Use Expedia’s search tool to filter for budget-friendly options and sort by price to find the best deals. Combining your hotel, flights, and activities into a package can yield further savings. Additionally, take advantage of affordable public transport and explore free attractions to maximise your experience without overspending.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Santa Cruz are January, June and August, where the prices are slightly lower. This is in comparison to March, September and December, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Santa Cruz is Saturday. The most expensive day to stay in Santa Cruz is Tuesday.
  • Find cheap hotels on Expedia: Utilise Expedia’s search tool to refine your preferences, such as budget, desired location, and the type of accommodation you prefer. To discover the most affordable prices and offers, sort the price filter from lowest to highest.
  • Consider bundling your trip: You can potentially save money by combining your hotel reservation in Santa Cruz with your flights and activities through an Expedia package.

Find the best attractions in Santa Cruz

Santa Cruz, Bolivia, offers a delightful blend of cultural and urban experiences, making it ideal for family vacations. Visitors can explore a variety of attractions, including national parks, cathedrals, and notable landmarks. The area's points of interest cater to those seeking cultural enrichment, outdoor adventures, and thrilling experiences, ensuring an unforgettable journey for every type of traveller.

  • Plaza 24 de Septiembre: Experience the vibrant heart of Santa Cruz in this bustling square, surrounded by charming colonial architecture. The plaza is a perfect spot to relax, people-watch, and immerse yourself in the local culture, with numerous cafes and shops nearby.
  • Amboró National Park: Adventure awaits in this stunning national park, renowned for its rich biodiversity and breathtaking landscapes. Explore lush forests, striking mountains, and diverse wildlife through various trails that cater to both novice and experienced hikers.
  • San Lorenzo Cathedral: Marvel at the intricate architecture and serene atmosphere of this historic cathedral. A symbol of faith and culture, it invites visitors to appreciate its beautiful interiors and the spiritual ambience that permeates the space.

Best time to go to Santa Cruz

The best time to visit Santa Cruz can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Santa Cruz falls in October, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature in Santa Cruz falls in June, visitor numbers are average and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January78.3°F (25.700000000000003°C)Light RainMostly SunnySlightly LowSlightly Low
February77.0°F (25.0°C)Light RainMostly CloudySlightly HighAverage
March76.5°F (24.700000000000003°C)Light RainMostly SunnyAverageSlightly High
April74.5°F (23.6°C)Light RainMostly SunnyAverageAverage
May70.2°F (21.200000000000003°C)Light RainMostly SunnySlightly LowAverage
June67.8°F (19.9°C)Light RainMostly SunnyAverageSlightly Low
July68.5°F (20.3°C)No RainMostly SunnyAverageAverage
August72.9°F (22.700000000000003°C)No RainSunnySlightly HighSlightly Low
September77.9°F (25.5°C)Light RainSunnySlightly HighSlightly High
October79.5°F (26.4°C)Light RainMostly SunnyAverageAverage
November79.3°F (26.3°C)Light RainMostly SunnyAverageAverage
December78.4°F (25.8°C)Light RainMostly SunnySlightly LowSlightly High

The nearest major airports for your trip to Santa Cruz

When visiting Santa Cruz, Bolivia, the primary airport to consider is Viru Viru International Airport (VVI), situated 16.1km from the city centre. Nearby accommodation options include the luxurious Marriott Santa Cruz de la Sierra Hotel and the upscale Swissôtel Santa Cruz De La Sierra, both within 14.5km. The Camino Real Hotel, a 4-star establishment, is also located 12.9km away. These hotels offer various transportation services, including on-request airport shuttles and scheduled availability. For those considering alternative airports, Monteagudo (MHW) and Potosi (POI) are located 241.4km and 331.5km away, respectively, with limited hotel options nearby.

Frequently asked questions

How much do hotels in Santa Cruz cost?
The season and factors like school holidays, Christmas and Easter can influence the price of a hotel in Santa Cruz. You can find cheap options from HK$296 in a few different ways on Expedia. First, key in the dates you'd like to go on holiday, then use the filters such as property type and amenities to refine your search. You can also sort by price, so the most inexpensive options appear at the top.
When is the best time to go to Santa Cruz?
If you're thinking of visiting in summer, reserve your Santa Cruz hotel between December and February. Temperatures during the summer here range from 22ºC to 31ºC. Santa Cruz has an oceanic climate, so pack appropriately.
Are there any luxury hotels in Santa Cruz?
Expedia has got some terrific stays for an indulgent escape in Santa Cruz, Santa Cruz, such as Hampton by Hilton Santa Cruz/Equipetrol, Bolivia. Check in and make use of amenities like concierge services, a garden and complimentary breakfast. Alternatively, treat yourself at Radisson Hotel Santa Cruz.
What are the top all-inclusive hotels in Santa Cruz?
If you're looking for a relaxed and worry-free escape, throw your bags down at Prince Hotel. Generally including your drinks, food and some recreational activities in the flat upfront rate, it's one of the best options for an all-inclusive retreat in Santa Cruz.
How can I find cheap hotels in Santa Cruz?
Discover inexpensive hotels with minimal effort by making use of our filter tool. Choose the "Price per night" box to view low-cost options in Santa Cruz. Another way is to take a look at our cheap hotels in Santa Cruz page. The lowest price available starts from HK$296 per night.
What are the best hotels in Santa Cruz for families?
Cosmopolitano Hotel Boutique is one of the top-rated hotels for families, located in Santa Cruz, Santa Cruz. Book here and take advantage of conveniences such as complimentary breakfast and a cafe. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is another favourite where kiddos are welcome. For more hotel options, fine-tune your search results by selecting "Family friendly" under the "Traveller experience" filter heading.
Why should I book my Santa Cruz hotel with Expedia?
Reserve a Santa Cruz hotel with Expedia for choice, price and ease. Also, our One Key™ rewards programme lets you earn OneKeyCash™* on eligible flights, car rentals, hotels, holiday rentals and more. Plus, we offer flexibility in case your plans change, and if you have any questions or require assistance, our online Help Centre is always available.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.