A beach with black volcanic rocks, clear turquoise water, and a distant shoreline with buildings.

Santa Cruz Island Holiday Rentals

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
17 Jul - 19 Jul
In two months
28 Aug - 30 Aug
In three months
25 Sept - 27 Sept
In four months
23 Oct - 25 Oct

Our top choices for Santa Cruz Island holiday rentals

Terrace/patio

Torre Mar Galapagos Boutique Suites

Torre Mar Galapagos Boutique Suites
3.0 star property
Puerto Ayora
9.2 out of 10, Wonderful, (24 reviews)
"Place was spotless! Very accommodating and helpful staff."
Canada
Nicholas
The price is HK$1,027
HK$1,027 total
30 Jun - 1 Jul
Torre Mar Galapagos Boutique Suites
Exterior

Suites

Suites
3.0 star property
Puerto Ayora
9.4 out of 10, Exceptional, (24 reviews)
"Check was early and friendly staff Room was super clean and comfortable"
United States
Judy
The price is HK$591
HK$653 total
30 Jun - 1 Jul
Suites
Outdoor dining

Modern apartment with 18 feet ceilings and private terrace with view to a park

Modern apartment with 18 feet ceilings and private terrace with view to a park
Puerto Ayora
10.0 out of 10, Exceptional, (23 reviews)
"I highly recommend you stay here. Its is beautiful and also away from the crowd noise."
United States
Richard
The price is HK$882
HK$1,196 total
30 Jun - 1 Jul
Modern apartment with 18 feet ceilings and private terrace with view to a park
Living area

Galapagos Coliving Ecuador Casa Tuna

Galapagos Coliving Ecuador Casa Tuna
3.0 star property
Puerto Ayora
The price is HK$847
HK$1,004 total
20 Jul - 21 Jul
Galapagos Coliving Ecuador Casa Tuna
Smart TV, books, stereo

Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora

Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora
Puerto Ayora
10.0 out of 10, Exceptional, (2 reviews)
"The place is perfect in every way, clean , spacious, great kitchen, comfortable beds, also the laundry facility is so helpful for longer stay. The host communication is excellent, immediate responds, great recommendations for the activities and local eats, location is also good , 10-15 minutes to walk to town center. we enjoyed our stay very much. highly recommend this place."
United States
Lihua
The price is HK$1,200
HK$1,725 total
30 Jun - 1 Jul
Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora
Terrace/patio

2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora

2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora
Puerto Ayora
The price is HK$533
HK$690 total
1 Jul - 2 Jul
2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora
Interior

Five minutes from the Malecon Santa Cruz - Puerto Ayora.

Five minutes from the Malecon Santa Cruz - Puerto Ayora.
Puerto Ayora
The price is HK$918
HK$1,369 total
5 Jul - 6 Jul
Five minutes from the Malecon Santa Cruz - Puerto Ayora.
Exterior

Villa Galapagos

Villa Galapagos
2.5 star property
Puerto Ayora
6.0 out of 10, (1 review)
"着いて早々にダブルブッキングがわかった。これは施設というよりも、貴社のシステムの問題。前回も宿泊名簿に名前がなかったこともあり、強く改善をもとめる。"
Japan
アオアシカツオドリ
The price is HK$706
HK$823 total
30 Jun - 1 Jul
Villa Galapagos
Exterior

TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal

TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"We enjoyed our 6-night stay at Ariana's. The apartment was large and comfortable. Bedroom air conditioners were whisper quiet. We especially enjoyed the rooftop terrace with its soft breezes. It’s a 20 minute walk to the big tortoise statue and a few minutes more to the Mlecon, or a 2 taxi ride."
Canada
Dean P.
The price is HK$541
HK$779 total
30 Jun - 1 Jul
TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal
Beach

Comfortable and cozy Galarous Island Suite

Comfortable and cozy Galarous Island Suite
Puerto Ayora
The price is HK$745
HK$902 total
5 Jul - 6 Jul
Comfortable and cozy Galarous Island Suite
6 bedrooms, WiFi

Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC

Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"Stay was great and I really enjoy Daniel’s helpful service— can’t wait to come back and stay again!"
United States
Will L.
The price is HK$784
HK$1,059 total
30 Jun - 1 Jul
Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC
Private kitchen

Pinzón Apartment in Puerto Ayora

Pinzón Apartment in Puerto Ayora
Puerto Ayora
Pinzón Apartment in Puerto Ayora
Property grounds

A nice place to stay with the family with spacious rooms

A nice place to stay with the family with spacious rooms
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"Javier and Marí were wonderful hosts. They were gracious, helpful, and friendly. They were very accommodating and gave us a number of great recommendations of places to eat, stores to go to, and things to do. They can also set up tours as needed."
United States
Jeffrey R.
The price is HK$212
HK$400 total
30 Jun - 1 Jul
A nice place to stay with the family with spacious rooms
Outdoor dining

Galarous island apartments

Galarous island apartments
Puerto Ayora
The price is HK$549
HK$706 total
30 Jun - 1 Jul
Galarous island apartments
Iron/ironing board, WiFi, bed sheets

Near Tortuga Bay Beach

Near Tortuga Bay Beach
Puerto Ayora
Near Tortuga Bay Beach
1 bedroom, iron/ironing board, free WiFi, bed sheets

Dominga Terrace

Dominga Terrace
Unknown
The price is HK$419
HK$772 total
26 Jul - 27 Jul
Dominga Terrace
2 bedrooms, WiFi, bed sheets

TWO Bedrooms Apartment ON THE First Floor Forest View

TWO Bedrooms Apartment ON THE First Floor Forest View
Puerto Ayora
The price is HK$541
HK$779 total
5 Jul - 6 Jul
TWO Bedrooms Apartment ON THE First Floor Forest View
Terrace/patio

¡Bienvenido a tu hogar isleño en Galápagos!

¡Bienvenido a tu hogar isleño en Galápagos!
Puerto Ayora
The price is HK$643
HK$800 total
30 Jun - 1 Jul
¡Bienvenido a tu hogar isleño en Galápagos!
1 bedroom, desk, free WiFi, bed sheets

Galarous Island Suite comfortable and cozy

Galarous Island Suite comfortable and cozy
Puerto Ayora
The price is HK$223
HK$380 total
30 Jun - 1 Jul
Galarous Island Suite comfortable and cozy
1 bedroom, iron/ironing board, free WiFi, bed sheets

NEAR THE SEE-DARWIN APARTMENT

NEAR THE SEE-DARWIN APARTMENT
Puerto Ayora
The price is HK$706
HK$968 total
5 Jul - 6 Jul
NEAR THE SEE-DARWIN APARTMENT
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Santa Cruz Island Hotel Reviews

Hotel Palace Galapagos

Hotel Palace Galapagos

10/10 Excellent
"Definitely recommend staying here, Fernando is great , always there to help and suggest ways to spend your days!"
Sonal 1-night trip
Posted 2 hours ago
Hotel Palace Galapagos

Find out more about Santa Cruz Island

Search for holiday rentals in Santa Cruz Island on Expedia! You can easily find your home rentals, villas, holiday apartments in Santa Cruz Island using one of the methods below:

  • View our selection of featured holiday rentals in Santa Cruz Island
  • Use the map to find apartments and other holiday homes in the Santa Cruz Island neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Santa Cruz Island while they last

Look no further and take a look at our great range of rental properties in Santa Cruz Island!