Best Santana Hotels in 2026 from HK$405 - Fully Refundable Options

A coastal landscape with a wooden deck, lush green foliage, and a view of the ocean under a cloudy sky.

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Our top choices for Santana hotels

In-room safe, laptop workspace, blackout curtains, soundproofing

1. Roça Santo António Ecolodge Hotel

Santana

"Very friendly and every time smiling service. They are well trained, but also hard treated by the boss. For example he never smiled or said hello. You feel this like a guest, too. We had a room on poolside. They rooms are very modern and comfy, but in the 3 rooms we went in had big mold patches everywhere. Everyday we had to pay our bills, like the ones for dinner. We asked for paying at checkout, they said it’s impossible etc. At the same moment our friends who sit next to us and can speak...

Daniel

HK$901

HK$1,757 total

includes taxes & fees

1 Oct - 2 Oct

In-room safe, desk, free WiFi, bed sheets

2. Omali São Tomé – Principe Collection

São Tomé

Kysha

HK$1,266

HK$1,494 total

includes taxes & fees

30 Sept - 1 Oct

3. Miramar São Tomé

São Tomé

sandra

HK$1,498

HK$1,723 total

includes taxes & fees

24 Sept - 25 Sept

Outdoor pool, pool umbrellas, pool loungers

4. Hotel Praia

São Tomé

Jonathan

HK$1,109

HK$1,275 total

includes taxes & fees

22 Sept - 23 Sept

5. Emoyeni Gardens Hotel

Vila Maria

HK$1,196

HK$1,375 total

includes taxes & fees

22 Sept - 23 Sept

6. Hotel Kenito

São Tomé

Ada

HK$628

HK$722 total

includes taxes & fees

22 Sept - 23 Sept

7. Welfare Agroturismo

Trindade

HK$599

HK$689 total

includes taxes & fees

22 Sept - 23 Sept

8. SH Boutique Hotel

São Tomé

Simon Peter

HK$670

HK$770 total

includes taxes & fees

17 Oct - 18 Oct

Minibar, desk, laptop workspace, blackout curtains

9. Hotel Central

São Tomé

Adam

HK$390

HK$448 total

includes taxes & fees

27 Sept - 28 Sept

Hypo-allergenic bedding, desk, free WiFi, individually decorated

10. Casa de Ferias

São Tomé

Lars Roland

HK$138

HK$556 total

includes taxes & fees

23 Sept - 24 Sept

11. Agua Leve

São Tomé

HK$388

HK$446 total

includes taxes & fees

22 Sept - 23 Sept

Desk, soundproofing, free WiFi, bed sheets

12. Praia Accommodation

São Tomé

Daniel

HK$890

HK$1,024 total

includes taxes & fees

23 Sept - 24 Sept

Minibar, in-room safe, free WiFi, bed sheets

13. Pestana São Tomé

Vila Maria

alexander

HK$1,927

HK$2,216 total

includes taxes & fees

22 Sept - 23 Sept

Desk, blackout curtains, soundproofing, iron/ironing board (on request)

14. Guest House Quinta Natural

Trindade

HK$286

HK$453 total

includes taxes & fees

22 Sept - 23 Sept

15. Roulotte Beach São Tomé

Conde

HK$707

HK$813 total

includes taxes & fees

1 Oct - 2 Oct

Iron/ironing board (on request), free WiFi

16. Alojamento Santos Silva

São Tomé

HK$2,468

HK$2,838 total

includes taxes & fees

22 Sept - 23 Sept

17. Mucumbli Hotel

Neves

Morten

HK$1,099

HK$1,264 total

includes taxes & fees

24 Sept - 25 Sept

18. Refúgio da Ilha

Conde

HK$389

HK$448 total

includes taxes & fees

22 Sept - 23 Sept

19. Residencial Aeroporto

São Tomé

HK$496

HK$570 total

includes taxes & fees

22 Sept - 23 Sept

20. Hotel Vitória

São Tomé

Anonymous traveller

HK$470

HK$541 total

includes taxes & fees

22 Sept - 23 Sept

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Learn more about Santana

Head to Estadio Nacional 12 de Julho and São Sebastião Museum—just two of the sights around Santana.

See all hotels in Santana

Top Santana Hotel Reviews

Hotel Central

10/10 Excellent

"Hotel was good. Walking distance from everything in the city. The staff is helpful. The Wi-Fi is OK but for the money and cleanliness this is the best option in the city."

More cheap stays in Santana

Nour Apartments

Rua 3 de Fevereiro São Tomé

HK$381

HK$438 total

25 Sept - 26 Sept

includes taxes & fees

Hotel Kenito

Campo de Milho São Tomé

HK$628

HK$722 total

22 Sept - 23 Sept

includes taxes & fees

Praia Inhame Eco-Lodge

Porto Alegre 64 Malanza

HK$689

HK$793 total

13 Oct - 14 Oct

includes taxes & fees

8.8/10 Excellent! (27 reviews)

Sweet Guest House

Vila Dolores n. 087 São Tomé

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Inviting 10 Bed Apartment in Sao Tome

Avenida Marginal 12 de Julho São Tomé São Tomé

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Pousada Roça São João dos Angolares

Cidade dos Angolares São João dos Angolares Sao Tome

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Frequently asked questions

Where is the best place to stay in Santana?

Based on our traveller data, Roça Santo António Ecolodge Hotel is one of the top choices for your stay. This hotel offers free breakfast and a restaurant. Pool and Beach Villa in Santana is another good choice for your visit. See all available top hotels, or vacation rentals in Santana.

What are some of the best holiday rentals that Santana has to offer?

Alojamento Santos Silva: This holiday home rental outside of Santana offers an outdoor pool, a garden and laundry facilities to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include an oven, a microwave and kitchenware. See all vacation rentals in Santana.

If I need to cancel my hotel reservation in Santana, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santana.

What's the best family accommodation in Santana?

Roça Santo António Ecolodge Hotel is a hotel with a children's pool and a restaurant, and it's a top choice on Expedia for families. Also, attractions in the area such as Cloçon Téla Chocolate Factory are fun for the whole family. Find more child-friendly accommodations in Santana.

What are some accommodation options with pools in Santana?

Roça Santo António Ecolodge Hotel is a top hotel with a children's pool, an outdoor pool and free buffet breakfast. View all hotels with pools in Santana.

How is it to stay in Santana?

Those travelling to Santana will definitely enjoy the sights to see and things to do. In Santana, there are 4 hotels and other accommodation options to choose from. Find out more about Santana.

What are the top places to visit in Santana?

Places to visit in the wider area include Estadio Nacional 12 de Julho, São Sebastião Museum and São Nicolau Waterfall. You'll also find Pico São Tomé and Paroquia da Santissima Trindade in the area. Take a look at what more there is to see and do in Expedia's Santana guide.

What's the weather like in Santana?

The hottest months are usually March and April, with an average temperature of 28°C, while the coldest months are July and August, with an average of 25°C. The rainiest months in Santana are November, October, December and April, with each month seeing an average of 249 mm of rainfall.

Santana hotels from HK$405

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Santana

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Santana hotels

1. Roça Santo António Ecolodge Hotel

2. Omali São Tomé – Principe Collection

3. Miramar São Tomé

4. Hotel Praia

5. Emoyeni Gardens Hotel

6. Hotel Kenito

7. Welfare Agroturismo

8. SH Boutique Hotel

9. Hotel Central

10. Casa de Ferias

11. Agua Leve

12. Praia Accommodation

13. Pestana São Tomé

14. Guest House Quinta Natural

15. Roulotte Beach São Tomé

16. Alojamento Santos Silva

17. Mucumbli Hotel

18. Refúgio da Ilha

19. Residencial Aeroporto

20. Hotel Vitória

Learn more about Santana

Top Santana Hotel Reviews

Hotel Central

More cheap stays in Santana

Nour Apartments

Hotel Kenito

Praia Inhame Eco-Lodge

Sweet Guest House

Inviting 10 Bed Apartment in Sao Tome

Pousada Roça São João dos Angolares

Frequently asked questions

Go further with the Expedia app