A calm lake with mountains in the background.

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Check prices for these dates

In two weeks
30 Oct - 1 Nov
In two months
11 Dec - 13 Dec
In three months
8 Jan - 10 Jan
In four months
5 Feb - 7 Feb

Our top choices for Seneca holiday homes

A bedroom with a bed, a nightstand, a lamp, a window with blinds, a ceiling fan, and a painting on the wall.

1. Peaceful 3-bedroom home 4 miles from Clemson.

Peaceful 3-bedroom home 4 miles from Clemson.
Seneca
The price is HK$848
HK$2,236 total
includes taxes & fees
19 Oct - 20 Oct
Peaceful 3-bedroom home 4 miles from Clemson.
A bedroom with a bed, dresser, mirror, ceiling fan, and a door.

2. Walk to Boat Ramp Lake Keowee w/ Parking + Firepit

Walk to Boat Ramp Lake Keowee w/ Parking + Firepit
Seneca
2.0 out of 10, (1 review)
The price is HK$1,001
HK$3,348 total
includes taxes & fees
19 Oct - 20 Oct
Walk to Boat Ramp Lake Keowee w/ Parking + Firepit
Room

3. 13 Min Oconee Nuclear 15 Min Clemson Stadium

13 Min Oconee Nuclear 15 Min Clemson Stadium
Seneca
The price is HK$998
HK$1,253 total
includes taxes & fees
25 Oct - 26 Oct
13 Min Oconee Nuclear 15 Min Clemson Stadium
A bedroom with a bed, a dresser, a nightstand, a lamp, and a painting on the wall.

4. Renovated 3BR near Lake Keowee & Clemson

Renovated 3BR near Lake Keowee & Clemson
Seneca
10.0 out of 10, Exceptional, (2 reviews)
"Fantastic location and really nicely done home. It was a perfect touch having a desk in one of the rooms to be able to get work done."
United States
Brenda B.
The price is HK$1,356
HK$2,885 total
includes taxes & fees
20 Oct - 21 Oct
Renovated 3BR near Lake Keowee & Clemson
A living room with a large tiger mural, a fireplace, a sofa, and a coffee table.

5. Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!

Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!
Downtown
10.0 out of 10, Exceptional, (23 reviews)
"Great host! We had a great experience during our stay. "
United States
David E.
The price is HK$1,263
HK$2,886 total
includes taxes & fees
26 Oct - 27 Oct
Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!
A spacious living room with a sofa, chairs, a wooden coffee table, and a fireplace.

6. Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock

Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock
Seneca
8.0 out of 10, Very good, (7 reviews)
"Adorable and clean house! The yard is beautiful "
United States
Diana H.
The price is HK$1,288
HK$2,298 total
includes taxes & fees
19 Oct - 20 Oct
Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock
A modern kitchen with a central island, wooden cabinets, and a built-in refrigerator.

7. 3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson

3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson
Seneca
9.8 out of 10, Exceptional, (12 reviews)
"Easy check in, pet-friendly, great location!!"
United States
Jason M.
The price is HK$1,766
HK$3,013 total
includes taxes & fees
19 Oct - 20 Oct
3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson
A wooden deck with a railing overlooking a forested area during sunset.

8. Waterfront 3br home on Lake Hartwell near Clemson

Waterfront 3br home on Lake Hartwell near Clemson
Seneca
9.8 out of 10, Exceptional, (18 reviews)
"Planning was super simple and the host is very responsive!"
United States
Trevor&Shaya Z.
The price is HK$2,017
HK$4,265 total
includes taxes & fees
19 Oct - 20 Oct
Waterfront 3br home on Lake Hartwell near Clemson
A modern kitchen with white cabinetry, a central island, and a large window.

9. The Big Golf House- 10 miles to Clemson

The Big Golf House- 10 miles to Clemson
Seneca
10.0 out of 10, Exceptional, (4 reviews)
"Great house and host!"
United States
David E.
The price is HK$1,992
HK$4,764 total
includes taxes & fees
26 Oct - 27 Oct
The Big Golf House- 10 miles to Clemson
A covered porch with wicker furniture, a wooden table, and a ceiling fan.

10. Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium

Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium
Seneca
9.6 out of 10, Exceptional, (13 reviews)
"Everything was lovely."
United States
Allison C.
The price is HK$2,561
HK$5,453 total
includes taxes & fees
19 Oct - 20 Oct
Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium
A cozy living room with a fireplace, a dining area with a table and chairs, and a kitchen in the background.

11. Clemson Memorabilia House Frank Howard III’s Home

Clemson Memorabilia House Frank Howard III’s Home
Clemson
8.4 out of 10, Very good, (20 reviews)
"Great location!"
United States
Libby S.
The price is HK$659
HK$2,073 total
includes taxes & fees
19 Oct - 20 Oct
Clemson Memorabilia House Frank Howard III’s Home
A church interior with pews, a cross, and a view of a landscape through a large window.

12. The Rustic Rectangle

The Rustic Rectangle
Pendleton
10.0 out of 10, Exceptional, (13 reviews)
"Cozy, clean and quiet! Loved that we could have our dogs stay with us! "
United States
Jennifer T.
The price is HK$678
HK$1,798 total
includes taxes & fees
25 Oct - 26 Oct
The Rustic Rectangle
A modern kitchen with a dining area, wooden flooring, and a ceiling fan.

13. Our Nest, a well loved quiet retreat in Foxwood Hills Resort near Lake Hartwell.

Our Nest, a well loved quiet retreat in Foxwood Hills Resort near Lake Hartwell.
Westminster
9.8 out of 10, Exceptional, (10 reviews)
"Outstanding place and host. Will definitely stay here again. "
United States
William H. J.
The price is HK$833
HK$1,936 total
includes taxes & fees
19 Oct - 20 Oct
Our Nest, a well loved quiet retreat in Foxwood Hills Resort near Lake Hartwell.
A lakeside cabin with a dock, a floating platform, and a house in the background.

14. Lakefront Private Cove Retreat w/ Sandy Beach, Dock, Hot Tub + Boat & Ski Option

Lakefront Private Cove Retreat w/ Sandy Beach, Dock, Hot Tub + Boat & Ski Option
West Union
9.6 out of 10, Exceptional, (17 reviews)
"Great home. Neat and Clean. We had family 3-70 and there was something for everyone to do and enjoy during our stay. Host was very prompt with communication and answering my questions. Would stay here again."
United States
April O.
The price is HK$4,534
HK$10,133 total
includes taxes & fees
27 Oct - 28 Oct
Lakefront Private Cove Retreat w/ Sandy Beach, Dock, Hot Tub + Boat & Ski Option
A covered porch with a wicker chair, a sofa with patterned cushions, and a small table with a plant.

15. Dream Weaver Cottage • Private Hot Tub • Fenced Yard • Pets Stay Free

Dream Weaver Cottage • Private Hot Tub • Fenced Yard • Pets Stay Free
Westminster
10.0 out of 10, Exceptional, (32 reviews)
"Fantastic property that was very clean and decorated really cute. We will come again."
United States
Pamela S.
The price is HK$1,986
HK$3,980 total
includes taxes & fees
19 Oct - 20 Oct
Dream Weaver Cottage • Private Hot Tub • Fenced Yard • Pets Stay Free
A single-story house with a porch, a fenced yard, and a clear sky.

16. Charming 2-bedroom house in Clemson 4mi. from Death Valley and 1mi. from Mac's

Charming 2-bedroom house in Clemson 4mi. from Death Valley and 1mi. from Mac's
Clemson
10.0 out of 10, Exceptional, (6 reviews)
"It was a cute house in a quiet area, but easy to get to campus . It has a nice kitchen and even a porch with an eating area overlooking the big back yard"
United States
Katherine
The price is HK$3,532
HK$5,924 total
includes taxes & fees
25 Oct - 26 Oct
Charming 2-bedroom house in Clemson 4mi. from Death Valley and 1mi. from Mac's
A kitchen with white cabinets, a stainless steel refrigerator, and a countertop with a flower arrangement and a bag.

17. Large 3 Bedroom Townhome Downtown Clemson and garage! Walk to Clemson Stadium!

Large 3 Bedroom Townhome Downtown Clemson and garage! Walk to Clemson Stadium!
Clemson
The price is HK$1,962
HK$4,312 total
includes taxes & fees
19 Oct - 20 Oct
Large 3 Bedroom Townhome Downtown Clemson and garage! Walk to Clemson Stadium!
A wooden deck with a round table and chairs, overlooking a lake.

18. Lake Hartwell Covered Dock & Sunset Beach 3BD, 1BA

Lake Hartwell Covered Dock & Sunset Beach 3BD, 1BA
Fair Play
9.6 out of 10, Exceptional, (62 reviews)
"The cottage was very nice. Great view of the water. super easy walk to the water. Dock & kayaks were enjoyed. "
United States
Steve A.
Lake Hartwell Covered Dock & Sunset Beach 3BD, 1BA
A two-story house with a balcony, wooden deck, and string lights.

19. Clemson|SUPs|ParkPass|PizzaOven|PortmanMarina|EV

Clemson|SUPs|ParkPass|PizzaOven|PortmanMarina|EV
Anderson
10.0 out of 10, Exceptional, (13 reviews)
"Beautifully decorated and updated condo. It was so private it felt like a single home. Very thoughtful details throughout from the decor to the house supplies. We stayed to move my daughter into Clemson so didn’t take advantage of the lake or boards but there is a nice outdoor deck and even a fire pit. Very comfy vibe! About 15 to 20 minutes from campus, easy to get around."
United States
Diana
The price is HK$1,036
HK$3,563 total
includes taxes & fees
2 Nov - 3 Nov
Clemson|SUPs|ParkPass|PizzaOven|PortmanMarina|EV
A cabin-style building with a wooden exterior, large windows, and a view of the water.

20. 2 Bedroom Lake Front Tiny Home in Anderson, beside Legendary Green Pond Landing

2 Bedroom Lake Front Tiny Home in Anderson, beside Legendary Green Pond Landing
Anderson
10.0 out of 10, Exceptional, (4 reviews)
"The place was beautiful and immaculate. It was perfect for our family of 3. Loved that we could see the lake from the porch."
United States
Lisa B.
The price is HK$1,236
HK$2,714 total
includes taxes & fees
19 Oct - 20 Oct
2 Bedroom Lake Front Tiny Home in Anderson, beside Legendary Green Pond Landing
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Seneca Hotel Reviews

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area

8/10 Good
"A nice variety for breakfast."
Angela 2-night trip
Posted 2 hours ago
Fairfield Inn & Suites Seneca Clemson Univ Area

Find out more about Seneca

Seneca Vacation Homes information

Number of reviews
163
Accommodation
733 Vacation Homes
Lowest Price
HK$1,798
Highest Price
HK$10,133

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