Best Southeast Iowa Hotels in 2026 from HK$409 - Fully Refundable Options

A paved courtyard with a brick pathway, trees, and a distant view of a road and buildings.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in Southeast Iowa

Pet friendly

Apartment

Pool

Condo

Family friendly

Waterpark

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Southeast Iowa hotels

A lobby with a stone fireplace, comfortable seating, and a flat-screen TV mounted on the wall.

A fire pit surrounded by outdoor furniture, including a sofa and chairs, in a patio area.

A spacious lobby with a leather sofa, dining area, and a TV mounted on a stone wall.

A reception area with a reception desk, a plant, and a sign for Boulders Inn & Suites.

1. Cobblestone Inn & Suites - Fort Madison

Fort Madison

Hunter

HK$965

HK$1,081 total

includes taxes & fees

3 Oct - 4 Oct

A spacious living room with a large sofa, two armchairs, a coffee table, and a fireplace.

A modern kitchen with a granite countertop, wooden chairs, and a large painting of a colorful horse.

A hotel room with a bed, a TV, a desk, and a chair.

A cozy living room with a grey sofa, two patterned armchairs, a wooden coffee table, and a brick accent wall.

2. AmericInn by Wyndham Mount Pleasant

Mount Pleasant

brian

HK$607

HK$680 total

includes taxes & fees

1 Nov - 2 Nov

A spacious living area with a wooden staircase, a stone fireplace, and a reception desk.

A hotel room with a bed, a desk, a sofa, a lamp, and a mirror.

A reception area with a stone wall, wooden reception desk, and a sign that reads "Quality".

A hotel room with two beds, a large window, a standing lamp, and a patterned carpet.

3. Quality Inn & Suites Fort Madison near Hwy 61

Fort Madison

Sharon

HK$745

HK$834 total

includes taxes & fees

1 Nov - 2 Nov

An indoor swimming pool with a wooden ceiling and walls, a bench, and a rack of towels.

A guest registration area with a counter, informational signs, and various items on shelves.

A small room with a wooden dresser, a desk, a mirror, a television, and a fan.

A hotel room with a bed, bedside lamps, a nightstand, a refrigerator, and a wooden headboard.

4. The Inn at Old Nauvoo

Nauvoo

Cindy

HK$960

HK$1,084 total

includes taxes & fees

1 Nov - 2 Nov

An indoor swimming pool with a wooden ceiling, grey tiled floor, and several lounge chairs and tables around the pool area.

A multi-story hotel with a central entrance, a parking lot, and a clear sky.

A modern hotel lobby with blue and pink seating, a central coffee table, and a kitchen area in the background.

A spa area with a hot tub, wooden ceiling, and tiled walls.

5. Quality Inn & Suites Keokuk North

Keokuk

Susan

HK$757

HK$847 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a bed, a sofa, a small table, a chair, a nightstand, and a painting on the wall.

A home gym with a treadmill, elliptical, and stationary bike, a large mirror, and a framed picture on the wall.

A modern reception area with a dark granite counter, light-colored walls, and a seating area with a sofa and chairs.

A modern kitchen with a dining area, featuring a central island, built-in appliances, and a large window with blinds.

6. Best Western Mt. Pleasant Inn

Mount Pleasant

Paul

HK$611

HK$685 total

includes taxes & fees

11 Oct - 12 Oct

A hotel room with two beds, a desk, a chair, and a large window.

A reception area with a white sofa, a potted plant, and a framed picture on the wall.

A Super 8 motel with a brick facade, a covered entrance, and a parking lot with cars.

A bathroom with a bathtub, toilet, and sink.

7. Super 8 by Wyndham Mt Pleasant

Mount Pleasant

frank

HK$573

HK$641 total

includes taxes & fees

1 Nov - 2 Nov

A large indoor swimming pool with a lifeguard chair, poolside chairs, and a view of the outside through large windows.

A Hampton Inn hotel with a covered entrance, a well-lit facade, and a landscaped front yard.

A breakfast buffet area with a sign reading "EAT HERE" and various food items like cereal and pastries.

A modern hotel room with a large bed, two bedside tables with lamps, a small sofa, and a desk.

8. Hampton Inn Keokuk

Keokuk

Kristopher

HK$880

HK$986 total

includes taxes & fees

1 Nov - 2 Nov

A patio area with Adirondack chairs and a central fire pit.

A spacious dining area with multiple tables and chairs, a television on a shelf, and a large chandelier.

A modern hotel with a brick facade, large windows, and a covered entrance.

A hotel room with a bed, a desk, a chair, and a TV.

9. Hampton Inn & Suites Burlington

Burlington

Susan

HK$961

HK$1,146 total

includes taxes & fees

11 Oct - 12 Oct

A room with a large window, a sofa, and a chair.

A brick building with a balcony, a staircase, and a sign reading "Zions Mercantile".

A living room with a flat-screen TV on a white console, a grey sofa, and a framed picture on the wall.

A bedroom with two beds, a ceiling fan, a TV, and a dresser.

10. Nauvoo Temple House Hotel

Nauvoo

Miranda

HK$775

HK$910 total

includes taxes & fees

31 Oct - 1 Nov

A Holiday Inn Express hotel with a covered entrance, multiple windows, and a well-lit facade.

A modern bathroom with a white sink, a mirror, and a coffee maker on a shelf.

A paved courtyard with a curved walkway, surrounded by trees and flowering plants.

A coffee station with two coffee machines and a variety of coffee pods and cups.

11. Holiday Inn Express Hotel & Suites Burlington by IHG

Burlington

Christina

HK$973

HK$1,121 total

includes taxes & fees

31 Oct - 1 Nov

A modern lounge area with a stone fireplace, a blue sofa, and a small table.

A modern lobby with a stone wall, a reception desk, and seating areas.

An indoor swimming pool with clear water, tiled walls, and several lounge chairs along the side.

A corner market with refrigerated beverage dispensers and shelves stocked with snacks.

12. Fairfield Inn & Suites by Marriott Burlington

Burlington

Matthew

HK$994

HK$1,142 total

includes taxes & fees

29 Oct - 30 Oct

A hotel room with a bed, a sofa, a chair, and a nightstand with lamps.

A bathroom with a marble-tiled wall, a large bathtub, a wooden vanity with a television, and a patterned rug.

A multi-story hotel with a covered entrance and a landscaped lawn.

A hotel lobby with red seating, a checkered floor, and a large beverage dispenser.

13. Quality Inn & Suites Mount Pleasant

Mount Pleasant

Holly

HK$533

HK$597 total

includes taxes & fees

1 Nov - 2 Nov

A bedroom with a bed, a wooden headboard, a nightstand, a lamp, a rug, and a door.

A stone building with a wooden door, illuminated by exterior lighting.

A dining area with a round table set for four, a wooden cabinet, and a kitchen area with shelves stocked with kitchenware.

A brick building with a porch, white doors, and hanging lights.

14. Willard Richards Inn

Nauvoo

Dre

HK$1,192

HK$1,430 total

includes taxes & fees

31 Oct - 1 Nov

A row of single-family homes with a well-maintained lawn and a tree in the foreground.

A modern kitchen with wooden cabinets, a white countertop, and a dining area with a white table and chairs.

A living room with a sofa, a patterned armchair, a dining table with chairs, a kitchen area with wooden cabinets and a refrigerator, and a television on a stand.

A compact kitchen with wooden cabinets, a microwave, a coffee maker, and a dishwasher.

15. Nauvoo Vacation Villas & Condos

Nauvoo

Renae

HK$1,130

HK$1,197 total

includes taxes & fees

3 Oct - 4 Oct

A well-lit indoor swimming pool with wooden walls and ceiling, surrounded by lounge chairs and umbrellas.

A restaurant with wooden furniture, a TV, a refrigerator, and a coffee machine.

A hotel room with two beds, a desk, a chair, a lamp, and a window with curtains.

A hotel with a covered entrance, a parking lot, and a sign indicating it is an Embassy Suites location.

16. AmericInn by Wyndham West Burlington

West Burlington

Jacqueline

HK$460

HK$515 total

includes taxes & fees

11 Oct - 12 Oct

A modern living room with a stone accent wall, a wooden desk with a computer, a black office chair, and a brown sofa set.

A hotel room with a bed, a sofa, a desk, a chair, a TV, and a painting on the wall.

A home gym with a bench press, a cable machine, and an elliptical.

A hotel lobby with a stone reception desk, a refrigerator, and a dining area with chairs and tables.

17. Super 8 by Wyndham Fort Madison

Fort Madison

Debbie

HK$565

HK$633 total

includes taxes & fees

1 Nov - 2 Nov

A lobby with a fireplace, seating area, and an exit sign.

A modern kitchen with a microwave, coffee machine, and a juice dispenser. There is a dining area with wooden tables and chairs.

A reception area with a wooden reception desk, a red accent wall, and a kitchenette with shelves stocked with snacks.

A hotel room with a large bathtub, a sofa, a chair, and a small table.

18. Comfort Suites Burlington

Burlington

Shawn

HK$837

HK$981 total

includes taxes & fees

1 Nov - 2 Nov

A park bench and a lamppost with flowers in the foreground.

A room with ornate woodwork, a chandelier, and patterned furniture.

A dining table with plates of food, candles, and a lamp.

A tree with yellow leaves in front of a brick building.

19. Nauvoo Grand Bed & Breakfast

Nauvoo

Henze

HK$1,365

HK$1,542 total

includes taxes & fees

3 Oct - 4 Oct

A compact kitchen with a microwave, stove, and sink. There is a cabinet with a mirror above the sink and a small shelf above the microwave. The kitchen has a tiled floor and yellow walls.

A compact kitchen with a built-in microwave, stove, and sink.

A small bathroom with a sink, mirror, and a microwave.

A reception desk with a wooden panel, a tiled floor, a chair, and a door.

20. Budget Inn

Keokuk

Deanna

HK$471

HK$527 total

includes taxes & fees

1 Nov - 2 Nov

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Southeast Iowa attractions

Joseph Smith Historic Site

9.2/10 (162 reviews)

You can learn about the history of Nauvoo with a trip to Joseph Smith Historic Site. While you're in the area, stroll along the riverfront.

See properties

Historic Nauvoo

9.6/10 (269 reviews)

Find out about the history of Nauvoo when you spend time at Historic Nauvoo. While you're in the area, stroll along the riverfront.

See properties

Lacey-Keosauqua State Park

8.6/10 (15 reviews)

Commune with nature and explore the great outdoors at Lacey-Keosauqua State Park during your travels in Keosauqua. Wander the parks and lakeside while you're in the area.

See properties

North Lee County Historical Society

7.6/10 (17 reviews)

You can browse the exhibits at North Lee County Historical Society, a museum with a storied past, during your holiday in Fort Madison. While you're in the area, stroll along the riverfront.

See properties

Lake Sugema

7.0/10 (2 reviews)

Commune with nature and explore the great outdoors at Lake Sugema during your travels in Keosauqua. Wander the parks and lakeside while you're in the area.

See properties

Snake Alley

8.6/10 (172 reviews)

Learn about the local history of Burlington when you spend time at Snake Alley. Visit the area's casinos or simply enjoy its bars.

See properties

C.E. Richards Arena

7.4/10 (18 reviews)

You can take time to visit C.E. Richards Arena during your travels to Fort Madison. Wander the riverfront in this family-friendly area.

See properties

Fort Madison Marina

7.6/10 (12 reviews)

Explore the waterfront in Fort Madison with a trip to Fort Madison Marina. Wander the riverfront in this family-friendly area.

See properties

Learn more about Southeast Iowa

Explore the family-friendly area of Southeast Iowa—a scenic riverfront, shopping and sights from Geode State Park to C.E. Richards Arena.

See all hotels in Southeast Iowa

Top Southeast Iowa Hotel Reviews

The Inn at Old Nauvoo

10/10 Excellent

"We had a great stay at the Inn at Old Nauvoo! Clean, comfortable, helpful staff, good breakfast, conveniently located close to the sites in Nauvoo we came to see. I would definitely recommend this place to anyone visiting Nauvoo."

Comfort Suites Burlington

8/10 Good

"Good deal. Big breakfast. Loved the indoor hot tub."

Super 8 by Wyndham Fort Madison

8/10 Good

"The breakfast was sorely lacking, but there is a wonderful cafe across the street. The price was right, the front desk attendant was great. I asked for extra towels and got them right away. It could have been a little more spiffed up and cleaned up, but all in all it was good. Oh, the pillows were big and hard. It was great for what we needed."

Nauvoo Vacation Villas & Condos

10/10 Excellent

"Great accommodations! The staff was incredible and could not have been better with their guests! The site was clean and just an enjoyable environment! We would definitely refer others to this property!"

Cobblestone Inn & Suites - Fort Madison

10/10 Excellent

"Everyone was super nice and helpful."

Hampton Inn & Suites Burlington

8/10 Good

"I booked through Expedia, staying two nights, Sat and Sun. One adult, no children, I paid $430 total. My brother and his wife stayed there also, but only Sunday night. They paid $120. There is no justification for such a disparity."

Holiday Inn Express Hotel & Suites Burlington by IHG

10/10 Excellent

"Every thing was clean, breakfast was ok. Need to do some touch up paint, staff was very friendly and helpful."

AmericInn by Wyndham West Burlington

10/10 Excellent

"Good"

More cheap stays in Southeast Iowa

Cobblestone Hotel & Suites - Ottumwa

108 Church St Ottumwa IA

HK$738

HK$826 total

3 Oct - 4 Oct

includes taxes & fees

9.4/10 Exceptional! (344 reviews)

Quality Inn & Suites Fort Madison near Hwy 61

6169 Reve Ct Fort Madison IA

HK$745

HK$834 total

1 Nov - 2 Nov

includes taxes & fees

8.6/10 Excellent! (657 reviews)

Quality Inn & Suites Keokuk North

3404 Main St Keokuk IA

HK$757

HK$847 total

1 Nov - 2 Nov

includes taxes & fees

Nauvoo Temple House Hotel

1200 Mulholland St Nauvoo IL

HK$775

HK$910 total

31 Oct - 1 Nov

includes taxes & fees

Cobblestone Inn & Suites - Fort Madison

4901 Avenue O Fort Madison IA

HK$965

HK$1,081 total

3 Oct - 4 Oct

includes taxes & fees

9.2/10 Wonderful! (731 reviews)

The Inn at Old Nauvoo

1875 Mulholland St Nauvoo IL

HK$960

HK$1,084 total

1 Nov - 2 Nov

includes taxes & fees

8.8/10 Excellent! (455 reviews)

Southeast Iowa hotels from HK$409

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Southeast Iowa

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Southeast Iowa hotels

1. Cobblestone Inn & Suites - Fort Madison

2. AmericInn by Wyndham Mount Pleasant

3. Quality Inn & Suites Fort Madison near Hwy 61

4. The Inn at Old Nauvoo

5. Quality Inn & Suites Keokuk North

6. Best Western Mt. Pleasant Inn

7. Super 8 by Wyndham Mt Pleasant

8. Hampton Inn Keokuk

9. Hampton Inn & Suites Burlington

10. Nauvoo Temple House Hotel

11. Holiday Inn Express Hotel & Suites Burlington by IHG

12. Fairfield Inn & Suites by Marriott Burlington

13. Quality Inn & Suites Mount Pleasant

14. Willard Richards Inn

15. Nauvoo Vacation Villas & Condos

16. AmericInn by Wyndham West Burlington

17. Super 8 by Wyndham Fort Madison

18. Comfort Suites Burlington

19. Nauvoo Grand Bed & Breakfast

20. Budget Inn

Stay near popular Southeast Iowa attractions

Joseph Smith Historic Site

Historic Nauvoo

Lacey-Keosauqua State Park

North Lee County Historical Society

Lake Sugema

Snake Alley

C.E. Richards Arena

Fort Madison Marina

Learn more about Southeast Iowa

Top Southeast Iowa Hotel Reviews

The Inn at Old Nauvoo

Comfort Suites Burlington

Super 8 by Wyndham Fort Madison

Nauvoo Vacation Villas & Condos

Cobblestone Inn & Suites - Fort Madison

Hampton Inn & Suites Burlington

Holiday Inn Express Hotel & Suites Burlington by IHG

AmericInn by Wyndham West Burlington

More cheap stays in Southeast Iowa

Cobblestone Hotel & Suites - Ottumwa

Quality Inn & Suites Fort Madison near Hwy 61

Quality Inn & Suites Keokuk North

Nauvoo Temple House Hotel

Cobblestone Inn & Suites - Fort Madison

The Inn at Old Nauvoo

Hotels in Southeast Iowa with star-rating

Explore a world of travel with Expedia

Go further with the Expedia app