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Hampton Inn & Suites St. Louis/South I-55

2.5 star property
Travelers start their day with a hearty breakfast buffet at this convenient hotel, perfectly positioned for exploring the attractions of St. Louis

Choose dates to view prices

Hampton Inn & Suites St. Louis/South I-55 combines comfort with practicality in an ideal location. Guests enjoy a satisfying breakfast buffet each morning, can relax beside the welcoming lobby fireplace, or take advantage of the indoor swimming pool during their stay.

Reviews

9.6 out of 10
Exceptional

Popular amenities

  • Pet-friendly
  • Parking included
  • Free Wi-Fi
  • Air-conditioning
The current price is HK$858
HK$986 total
includes taxes & fees
5 Apr - 6 Apr

Room options

Available filters for rooms
Showing 14 of 14 rooms

View all photos for Room

In-room safe, blackout curtains, iron/ironing board

Room

9.8 out of 10
Exceptional
(36 reviews)

Highlights

Air conditioning
Connecting rooms available
Free cots/infant beds
Fridge
LCD TV
Blackout curtains
Separate bedroom
Private bathroom
  • 460 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room

In-room safe, blackout curtains, iron/ironing board

Room

9.6 out of 10
Exceptional
(14 reviews)

Highlights

Air conditioning
Connecting rooms available
Free cots/infant beds
Fridge
LCD TV
Blackout curtains
Separate bedroom
Private bathroom
  • 460 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Room

In-room safe, blackout curtains, iron/ironing board

Room

9.6 out of 10
Exceptional
(4 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Free cots/infant beds
Fridge
LCD TV
Blackout curtains
Separate bedroom
  • 460 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed

View all photos for Room

In-room safe, blackout curtains, iron/ironing board

Room

10.0 out of 10
Exceptional
(2 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Free cots/infant beds
Fridge
LCD TV
Sofa bed
Blackout curtains
  • 460 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed

View all photos for Two Queen Beds, Non-Smoking, Accessible

In-room safe, blackout curtains, iron/ironing board

Two Queen Beds, Non-Smoking, Accessible

9.8 out of 10
Exceptional
(26 reviews)

Highlights

Air conditioning
Connecting rooms available
Free cots/infant beds
Fridge
LCD TV
Blackout curtains
Separate bedroom
Private bathroom
  • 460 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds

View all photos for One King Bed, Non-Smoking, Accessible

In-room safe, blackout curtains, iron/ironing board

One King Bed, Non-Smoking, Accessible

9.8 out of 10
Exceptional
(20 reviews)

Highlights

Air conditioning
Connecting rooms available
Free cots/infant beds
Fridge
LCD TV
Blackout curtains
Separate bedroom
Private bathroom
  • 460 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Studio, Accessible, Non Smoking

In-room safe, blackout curtains, iron/ironing board

Studio, Accessible, Non Smoking

8.0 out of 10
Very good
(6 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Free cots/infant beds
Fridge
LCD TV
Sofa bed
Blackout curtains
  • 460 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed

King Room-Non-Smoking

  • Sleeps 2

Guest Room With 1 King Bed And Mobility/Hearing Accessible With Tub-Nonsmoking

  • Sleeps 2

King Studio Suite With Whirlpool-Non-Smoking

  • Sleeps 3

2 Queen Beds Room, Non-Smoking

  • Sleeps 4

Mobility Hearing Accessible King Studio with Roll in Shower

  • Sleeps 3

2 Queens Mobility/Hearing Access Tub Nosmok

  • Sleeps 4

King Studio Suite-Non-Smoking

  • Sleeps 3

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  • Pool
  • Breakfast included
  • Pet-friendly
  • Free Wi-Fi
8.8 out of 10, Excellent, 1,003 reviews
The price is HK$821
HK$949 total
includes taxes & fees
15 Mar - 16 Mar
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About the area

St. Louis is home to Hampton Inn & Suites St. Louis/South I-55. St. Louis Zoo is a popular attraction and the area's natural beauty can be seen at Mississippi River and Forest Park. BounceU of St. Louis and Kennedy Rink are also worth visiting. Visit our St. Louis travel guide
Map
4200 Midamerica Lane, St. Louis, MO, 63129

What's nearby

  • St. Louis Cardinals Baseball.
    Busch Stadium
    16 min drive - 27.2 km
  • Gateway Arch featuring a monument, night scenes and a park
    Gateway Arch
    17 min drive - 27.8 km
  • Aerial view of vibrant downtown St. Louis with Enterprise Center and St. Louis Wheel, St. Louis, Missouri, United States.
    Enterprise Center
    17 min drive - 26.8 km
  • Union Station, St. Louis, MO
    St. Louis Union Station
    18 min drive - 27.2 km
  • Barnes Jewish South Campus
    5 min walk - 0.4 km

Getting around

  • Kirkwood Station
    14 min drive
  • Lambert-St. Louis International Airport (STL)
    31 min drive

Restaurants

  • McDonald's
    3 min drive
  • Burger King
    10 min walk
  • Popeyes Louisiana Kitchen
    3 min walk
  • Hardee's / Red Burrito
    10 min walk
  • Rich & Charlie's Italian Restaurant
    3 min drive

About this property

Hampton Inn & Suites St. Louis/South I-55

Hotel near Mississippi River
At Hampton Inn & Suites St. Louis/South I-55, you can look forward to a free breakfast buffet, a corner/local shop and dry cleaning/laundry services. Free in-room WiFi is available to all guests, along with a fireplace in reception and a gym.
Additional perks include:
  • An indoor pool
  • Free self-parking
  • Express check-in, free newspapers and a computer station
  • Laundry services, a vending machine and 1 meeting room
  • Guest reviews speak highly of the breakfast and helpful staff
Room features
All 92 rooms include comforts such as air conditioning, as well as perks such as free WiFi and safes. Guest reviews speak positively of the cleanliness rooms at the property.
More conveniences in all rooms include:
  • Bathrooms with free toiletries and hairdryers
  • 37-inch LCD TVs with cable channels
  • Wardrobes/cupboards, fridges and microwaves

Similar properties

Property amenity
Holiday Inn Express & Suites St. Louis South - I-55 by IHG
  • Pool
  • Breakfast included
  • Parking included
  • Free Wi-Fi
9.6 out of 10, Exceptional, 1,008 reviews
The price is HK$978
HK$1,124 total
includes taxes & fees
5 Apr - 6 Apr
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Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transport

  • Free self parking on site
  • Limited on-site self parking
  • Wheelchair-accessible parking and van parking available

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 10:00 AM
  • Coffee and tea in common areas

Things to do

  • Gym
  • Indoor pool
  • TV in common areas

Family friendly

  • Grocery/convenience store
  • In-room cot
  • In-room microwave
  • In-room refrigerator
  • Indoor pool
  • Laundry facilities

Conveniences

  • 24-hour front desk
  • ATM
  • Free newspapers in lobby
  • Grocery/convenience store
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Vending machine

Guest services

  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • 753 square feet of conference space
  • Business centre
  • Computer station
  • Meeting room

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Lift
  • Phone accessibility kit
  • Stair-free path to entrance
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business centre
  • Wheelchair-accessible concierge desk
  • Wheelchair-accessible gym
  • Wheelchair-accessible parking
  • Wheelchair-accessible path to lift
  • Wheelchair-accessible pool
  • Wheelchair-accessible public bathroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible van parking

More

  • 1 building
  • 5 floors
  • Banquet hall
  • Built in 2010
  • Fireplace in lobby
  • Smoke-free property

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Free cot

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Towels provided

Entertainment

  • 37-inch LCD TV with cable channels
  • Pay films

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Free local calls
  • Free weekday newspapers
  • Iron/ironing board
  • Phone
  • Safe

Policies

Check-in

Check-in start time: 3 PM; check-in end time: midnight
Contactless check-in and check-out are available
Express check-in available

Check-out

Check-out before 11 AM
Contactless check-out

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets are allowed for an extra charge of USD 75 per accommodation, per stay
Service animals are welcome, and are exempt from fees
Welcoming dogs and cats only
2 total pets
Pets cannot be left unattended

Children and extra beds

Children are welcome
Rollaway/extra beds are not available.
Free cots are available on request at the property

Payment types at the property

Important information

Optional extras

  • Pet fee: USD 75 per accommodation, per stay
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards and debit cards; cash is not accepted
This property reserves the right to pre-authorise the guest's credit card prior to arrival.

We should mention

Pool access available from 8 AM to 10 PM
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
Children under 13 years old are not allowed in the swimming pool or fitness facility without adult supervision
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

Hampton Inn St.Louis South I-55 Hotel St. Louis
Hampton Inn St.Louis South I-55 Hotel
Hampton Inn St.Louis South I-55 St. Louis
Hampton Inn St.Louis South I-55
Hampton & Suites St Louis I 55
Hampton Inn Suites St. Louis/South I 55
Hampton Inn Suites St.Louis South at I 55
Hampton Inn Suites St. Louis South I 55 MO
Hampton Inn & Suites St. Louis/South I-55 Hotel
Hampton Inn & Suites St. Louis/South I-55 St. Louis
Hampton Inn & Suites St. Louis/South I-55 Hotel St. Louis

Frequently asked questions

Does Hampton Inn & Suites St. Louis/South I-55 have a pool?

Yes, this property has an indoor pool. Pool access is from 8 AM to 10 PM.

How much does it cost to stay at Hampton Inn & Suites St. Louis/South I-55?

As of 10 Mar 2026, prices found for a 1-night stay for 2 adults at Hampton Inn & Suites St. Louis/South I-55 on 5 Apr 2026 start from HK$858, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is Hampton Inn & Suites St. Louis/South I-55 pet-friendly?

Yes, Hampton Inn & Suites St. Louis/South I-55 allows cats and dogs (limit 2 total). There's a fee of USD 75 per accommodation, per stay. Service animals are exempt from fees.

How much is parking at Hampton Inn & Suites St. Louis/South I-55?

Self-parking is free at this property.

What time is check-in at Hampton Inn & Suites St. Louis/South I-55?

Check-in start time: 3 PM; check-in end time: midnight.

What time is check-out at Hampton Inn & Suites St. Louis/South I-55?

Checkout is at 11 AM.

Where is Hampton Inn & Suites St. Louis/South I-55 located?

Situated in St. Louis, this hotel is 0.3 mi (0.6 km) from Barnes Jewish South Campus and within 3 miles (5 km) of BounceU of St. Louis and St Anthony's. Kindred Hospital St. Louis South and Kennedy Rink are also within 3 miles (5 km).

Can I cancel my reservation for free and receive a full refund?

Yes, this property offers free cancellation on selected room rates because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.

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Reviews

Hampton Inn & Suites St. Louis/South I-55 Reviews

9.6

Exceptional

9.8

Cleanliness

9.2

Location

9.8

Staff & service

9.6

Property conditions & facilities
Rating 10 - Excellent. 824 out of 1004 reviews
Rating 8 - Good. 129 out of 1004 reviews
Rating 6 - Okay. 27 out of 1004 reviews
Rating 4 - Poor. 5 out of 1004 reviews
Rating 2 - Terrible. 19 out of 1004 reviews

Reviews

8/10 Good

Jeffrey

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
The breakfast was good. The staff was friendly and they allowed us to check out late.
Stayed 1 night in Dec 2025

10/10 Excellent

Jerry

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Really nice rooms and staff , good breakfast!
Stayed 1 night in Sep 2025

10/10 Excellent

Amy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff was nice and friendly. Room was nice and clean.
Stayed 1 night in Nov 2025

10/10 Excellent

Eric

Liked: Cleanliness, amenities, property conditions & facilities
Big and comfortable rooms with excellent services
Stayed 1 night in Oct 2025

10/10 Excellent

Renee

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Very clean, modern rooms with a welcoming staff.
Stayed 1 night in Oct 2025

10/10 Excellent

SHELLY

Liked: Cleanliness, staff & service, amenities
Clean room, good breakfast. Nice, safe area. But the staff was the best I have encountered in a long time. From check in, check out to the breakfast staff. I cannot say enough. We stayed 12/6/25 - one night and I would come back in a heartbeat.
Stayed 1 night in Dec 2025

10/10 Excellent

Michael

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Loved the unique decor, the conference room, and the well attended bathrooms. Super helpful staff.
Stayed 1 night in Oct 2025

10/10 Excellent

Jane

Liked: Cleanliness, amenities, property conditions & facilities
The staff was wonderful and the location perfect!
Stayed 2 nights in Jun 2025

10/10 Excellent

Brittany

Liked: Cleanliness, staff & service, property conditions & facilities
Everything was great! Clean, comfortable and breakfast was fantastic!
Stayed 1 night in Jul 2025

10/10 Excellent

Angie

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Great stay

Convenient, clean and would stay there again if I needed to
Stayed 2 nights in Feb 2025

10/10 Excellent

Sandro

Liked: Cleanliness, staff & service, property conditions & facilities
Great experience for a weekend in St Louis, the hotel convenience is great, staff very polite in the breakfast and all match with the content in the site, recommend!
Stayed 2 nights in Jun 2025

10/10 Excellent

John

The best hotel staff I’ve ever encountered.
Stayed 2 nights in Jul 2025

10/10 Excellent

Ariona

Liked: Amenities
Our room was cleaned by Tiff and it was in perfect condition. Pool area was clean as well as the lobby and dining area. You can tell the staff cares. Everyone was very hospitable at breakfast. I also love that you can tip the support staff through the qr code. Would highly reccomend
Stayed 1 night in Aug 2025

8/10 Good

Michael

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
A good, simple, comfortable stay.
Stayed 4 nights in Dec 2024

10/10 Excellent

Michael

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Quick trip

Needed a hotel for an overnight. This was a great hotel. Very friendly staff and very clean. Good hot breakfast served. Would definitely stay there again if in the area.
Stayed 1 night in May 2025

10/10 Excellent

Shannon

Liked: Cleanliness, staff & service, property conditions & facilities
Big rooms and nice breakfast buffet
Stayed 1 night in Dec 2024

10/10 Excellent

Damon

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The staff was exceptionally nice and helpful
Stayed 2 nights in Mar 2025

10/10 Excellent

Lísbeth

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I’m a traveling band mom, so I’ve been in three different hotel franchises in the last three weeks. This was the best! When I walked in, I was shocked at how crisp and clean everything was. Great service, they let me check in early, which was extremely helpful. The room was noiiiiiice! And I really need to know where I can buy their shampoo and conditioner, because my hair has never been so manageable. I didn’t have time to swim, but their pool has play stuff and it’s nice and warm in there. I will be back! It’s a great distance from St Louis, you can get there in no time and still be in the burbs
Stayed 2 nights in Oct 2025

10/10 Excellent

Nicole

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed for a short time during our spring break travels. Easy in and out of the city but still felt very safe and comfortable.
Stayed 2 nights in Mar 2025

10/10 Excellent

Mike

Liked: Cleanliness, staff & service, property conditions & facilities
Like any other highway hotel it serves purpose, but we do stay here often. We have family in St. Louis and there are hundreds of choices for hotels. We choose this property brcause of the staff they are always friendly helpful and the hotel is always clean.
Stayed 2 nights in Mar 2025

8/10 Good

Kim

Liked: Cleanliness, property conditions & facilities, room comfort
Room was exceptionally comfortable and clean
Stayed 1 night in Dec 2024

10/10 Excellent

Jennifer

Liked: Cleanliness, staff & service, property conditions & facilities
Staff were extra friendly.
Stayed 2 nights in Mar 2025

10/10 Excellent

Kimberly

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I love this hotel any time I’m in St. Louis. The staff is amazing and the hotel is very clean. I will always stay here
Stayed 4 nights in Nov 2024

10/10 Excellent

Kenneth L. And Virginia

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Breakfast was well done and the staff very courteous.
Stayed 2 nights in Jun 2024

10/10 Excellent

Shane

Liked: Cleanliness, staff & service, property conditions & facilities
It was in a good location for our stay
Stayed 1 night in Aug 2023