A lake with lily pads and a forested shoreline.

Missouri City 4 Stars Hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Missouri City 4 Star Hotels

Tonight
22 Sept - 23 Sept
Tomorrow
23 Sept - 24 Sept
This weekend
25 Sept - 27 Sept
Next weekend
2 Oct - 4 Oct

Our top choices for Missouri City 4-star hotels

A spacious living area with a dining table, chairs, and a chandelier.
A high-rise hotel with a rooftop pool, multiple floors, and a city skyline in the background.
A restaurant with tables set for dining, surrounded by wicker chairs and potted plants.
A hotel room with a bed, a nightstand, a desk with a chair, a large mirror, and a chandelier.

1. Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District
South Central Houston
United States
Tina
HK$2,054
HK$2,772 total
includes taxes & fees
8 Oct - 9 Oct
Hotel Zaza Houston Museum District
A dining table with white tablecloth, two plates of food, two wine glasses, and a vase with white flowers.
A lobby with a chandelier, a reception desk, and a sign reading "RUSK HOUSE".
A staircase with a black handrail and a light fixture on the wall.
A building facade with three windows, each with a wooden frame and green curtains. Decorative columns with intricate carvings flank the windows.

2. Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston
Downtown Houston
United States
Alfredo
HK$767
HK$897 total
includes taxes & fees
24 Sept - 25 Sept
Club Quarters Hotel Downtown, Houston
A rooftop patio with outdoor seating, fire pits, and a view of the cityscape.
A modern bar area with a long counter, multiple seating options, and a variety of liquor bottles on shelves.
A modern lobby with seating areas, a reception desk, and decorative wall art.
An outdoor patio area with seating and a pool.

3. Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
Texas Medical Center
United States
olga
HK$830
HK$980 total
includes taxes & fees
11 Oct - 12 Oct
Hilton Houston Plaza/Medical Center
A high-rise hotel with a modern design, featuring a central courtyard with palm trees and a swimming pool.
A spacious lobby with a modern design, featuring a seating area with a sofa and chairs, a coffee table, and a dining area with a table and chairs.
A balcony with a view of a cityscape, a sofa, a small table, and a wooden wall.
A hotel room with two beds, a TV, a desk, and a large window with a view.

4. DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Greater Uptown
United States
Chisa
HK$1,022
HK$1,204 total
includes taxes & fees
3 Oct - 4 Oct
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
A modern hotel interior with a central spiral staircase, large glass windows, and a buffet area with various food items.
A multi-level hotel interior with a central spiral staircase, a glass elevator, and a patterned carpet.
A modern hotel with a curved entrance, a prominent logo, and a glass facade.
A hotel entrance with a modern design, a covered walkway, and a car parked outside.

5. The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria
The Galleria
United States
Dr. Zurick
HK$1,130
HK$1,322 total
includes taxes & fees
26 Sept - 27 Sept
The Royal Sonesta Houston Galleria
A spacious lobby with plush seating, a marble coffee table, and a grand chandelier.
A modern hotel room with a sofa, armchair, and a TV mounted on the wall.
A modern bar area with a sign reading "BLOSSOM Houston" and a variety of liquor bottles. There are plush seating arrangements and a decorative fountain in the foreground.
A hotel room with two beds, a desk, a chair, a TV, and a large window offering a city view.

6. Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton
Texas Medical Center
United States
Angela
HK$1,280
HK$1,503 total
includes taxes & fees
11 Oct - 12 Oct
Blossom Hotel Houston, Curio Collection by Hilton
A hotel entrance with a sign reading "MORAN" and a neon sign for "radiom ilano".
A modern bar area with a marble countertop, multiple bar stools, and a variety of bottles and glasses on shelves.
A hotel room with a bed, a desk, a sofa, and a TV.
An outdoor patio area with seating, a table, and a view of the cityscape.

7. The Moran CITYCENTRE

The Moran CITYCENTRE
Memorial
United States
Jayce
HK$1,538
HK$2,033 total
includes taxes & fees
17 Oct - 18 Oct
The Moran CITYCENTRE
An aerial view of a hotel with a distinctive pool area featuring a unique wavy design.
A hotel reception area with a wooden reception desk labeled 'XOCHI' and a 'hola' sign, a bench, and a wall of wine bottles.
A spacious lobby with a reception desk, seating area, and a chandelier.
An outdoor seating area with a central fire feature, surrounded by modern chairs and tables, overlooking a cityscape.

8. Marriott Marquis Houston

Marriott Marquis Houston
Downtown Houston
United States
Jacob
HK$2,228
HK$2,868 total
includes taxes & fees
11 Oct - 12 Oct
Marriott Marquis Houston
A modern living room with a glass table, a sofa, a TV, and a staircase with a city view.
A spacious lobby with a seating area, a large flat-screen TV, and a modern chandelier.
A modern hotel lobby with a sofa, dining area, and large windows.
A spacious dining area with high ceilings, large windows, and a green seating area.

9. DoubleTree by Hilton Hotel Houston - Greenway Plaza

DoubleTree by Hilton Hotel Houston - Greenway Plaza
Greenway Plaza-Upper Kirby
Australia
Chloe
HK$832
HK$973 total
includes taxes & fees
12 Oct - 13 Oct
DoubleTree by Hilton Hotel Houston - Greenway Plaza
A modern cityscape with high-rise buildings, including a curved skyscraper with illuminated windows and a rectangular building with a grid-like facade.
An outdoor seating area with tables and chairs, surrounded by greenery and illuminated by string lights.
A modern interior with multiple hanging lamps, a reception desk, and a view of the street outside.
A spacious indoor area with a bar, seating, and large windows offering views of the cityscape.

10. The Whitehall Houston

The Whitehall Houston
Downtown Houston
United States
Jose
HK$952
HK$1,114 total
includes taxes & fees
6 Oct - 7 Oct
The Whitehall Houston
A rooftop pool area with lounge chairs, a fire feature, and a neon sign for "RANCH WATER".
A modern hotel room with a large bed, a seating area with a sofa and armchairs, a side table with a vase, and a large window offering a city view.
A modern bar area with a long counter, bar stools, and a television screen. There are tables and chairs arranged for dining, and large windows with curtains.
A modern living room with a large sectional sofa, two armchairs, a coffee table, and a decorative vase.

11. Hyatt Regency Houston/Galleria

Hyatt Regency Houston/Galleria
Greater Uptown
United States
Maiesha
HK$1,161
HK$1,368 total
includes taxes & fees
18 Oct - 19 Oct
Hyatt Regency Houston/Galleria
A modern bar area with a central island, bar stools, and a glass display case filled with bottles.
A spacious dining area with a long table, multiple chairs, and a central plant.
A modern hotel with a large pool, surrounded by well-maintained lawns and trees.
A modern bedroom with a curved ceiling, a central chandelier, and a bed with pillows and a blanket.

12. Omni Houston Hotel

Omni Houston Hotel
Greater Uptown
United Kingdom
Graham
HK$1,155
HK$1,371 total
includes taxes & fees
18 Oct - 19 Oct
Omni Houston Hotel
A modern high-rise building with a glass facade, multiple floors, and a rooftop parking area.
A modern hotel lobby with a bar area, seating arrangements, and large windows providing natural light.
A modern living room with a large window, a flat-screen TV, a green sofa, a glass coffee table, and a dining area with a table and chairs.
A rooftop pool with lounge chairs and a view of city buildings.

13. The Laura Hotel, Houston Downtown, Autograph Collection

The Laura Hotel, Houston Downtown, Autograph Collection
Downtown Houston
United States
Charles
HK$1,247
HK$1,706 total
includes taxes & fees
26 Sept - 27 Sept
The Laura Hotel, Houston Downtown, Autograph Collection
A swimming pool with a sunlit water surface and a cityscape in the background.
A modern hotel with a prominent Hilton sign, large glass windows, and a well-lit lobby area.
A rooftop lounge with outdoor seating, potted plants, and cocktails on a table.
A lobby with a Christmas tree, white light decorations, and red poinsettias.

14. Hilton Americas-Houston

Hilton Americas-Houston
Downtown Houston
United States
Diana
HK$1,509
HK$1,781 total
includes taxes & fees
25 Sept - 26 Sept
Hilton Americas-Houston
A modern living room with a large flat-screen TV, comfortable seating, and a city view through large windows.
A modern hotel lobby with a bar area, seating arrangements, and a decorative ceiling.
A modern living room with a large window, a brown sofa with patterned cushions, a glass partition, and a dining area with chairs and a table.
A modern hallway with a herringbone floor, a large wooden door, a chandelier, and two abstract paintings on the wall.

15. The Westin Galleria Houston

The Westin Galleria Houston
The Galleria
United States
Sara
HK$1,500
HK$2,006 total
includes taxes & fees
27 Sept - 28 Sept
The Westin Galleria Houston
An indoor swimming pool with a glass-domed structure, surrounded by blue-tinted walls and a stone-tiled floor.
A spacious lobby with a large chandelier, marble flooring, and a reception area with seating.
A modern interior with a glass door leading to a dining area, a wine cellar with glass shelves, and a marble floor.
A grand lobby with a marble floor, a glass staircase, and a ceiling with a starry sky design.

16. Grand Tuscany Hotel

Grand Tuscany Hotel
Fairbanks
United States
Juan
HK$726
HK$850 total
includes taxes & fees
23 Sept - 24 Sept
Grand Tuscany Hotel
A grand staircase with multiple steps, black railings, and lit candles on each step.
A rooftop pool with lounge chairs and a city view at night.
A spacious restaurant with high ceilings, multiple dining tables, wicker chairs, and a bar area with a large selection of bottles.
The exterior of the Magnolia hotel with three flags, a large entrance, and a modern facade.

17. Magnolia Hotel Houston, A Tribute Portfolio Hotel

Magnolia Hotel Houston, A Tribute Portfolio Hotel
Downtown Houston
United States
Krystal
HK$1,010
HK$1,206 total
includes taxes & fees
1 Oct - 2 Oct
Magnolia Hotel Houston, A Tribute Portfolio Hotel
A modern interior with a bar area, seating, and large windows offering a city view.
An outdoor patio with round tables and chairs, surrounded by greenery and modern buildings in the background.
A cozy indoor seating area with cushioned sofas and wooden chairs, surrounded by potted plants and a large window with natural light.
A modern living room with a fireplace, sofas, and a coffee table.

18. C. Baldwin, Curio Collection by Hilton

C. Baldwin, Curio Collection by Hilton
Downtown Houston
United States
Zoe
HK$1,509
HK$1,973 total
includes taxes & fees
25 Sept - 26 Sept
C. Baldwin, Curio Collection by Hilton
A conference room with a large screen displaying a cityscape, multiple tables and chairs, and modern chandeliers.
A modern lobby with a reception desk, seating area, and a decorative plant centerpiece.
A modern gym with various exercise equipment, a large mirror, and a television on the wall.
A modern hallway with a geometric patterned wall, a bench, and a large mirror.

19. Thompson Houston, by Hyatt

Thompson Houston, by Hyatt
Fourth Ward
United States
Haibullo
HK$1,993
HK$2,666 total
includes taxes & fees
11 Oct - 12 Oct
Thompson Houston, by Hyatt
A modern bar area with multiple shelves of liquor bottles, a central bar counter, and seating with tables and chairs.
A modern hotel lobby with a seating area, a luggage trolley, and a large plant.
Two people sitting by a pool with a black door and white walls in the background.
A modern lobby with a large abstract painting, a chandelier, and a seating area with a coffee table.

20. The Chifley Houston, Tapestry Collection by Hilton

The Chifley Houston, Tapestry Collection by Hilton
The Galleria
United States
Fouad
HK$1,087
HK$1,272 total
includes taxes & fees
3 Oct - 4 Oct
The Chifley Houston, Tapestry Collection by Hilton
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Missouri City.
The Post Oak Hotel at Uptown Houston

The Post Oak Hotel at Uptown Houston

1600 West Loop South Houston TX
HK$4,660
HK$5,452 total
11 Oct - 12 Oct
includes taxes & fees
9.6/10 Exceptional! (1,005 reviews)
The Post Oak Hotel at Uptown Houston
Four Seasons Hotel Houston

Four Seasons Hotel Houston

1300 Lamar St Houston TX
HK$4,785
HK$5,638 total
3 Oct - 4 Oct
includes taxes & fees
Four Seasons Hotel Houston
JW Marriott Houston Downtown

JW Marriott Houston Downtown

806 Main Street Houston TX
HK$1,927
HK$2,310 total
25 Sept - 26 Sept
includes taxes & fees
9/10 Wonderful! (1,001 reviews)
JW Marriott Houston Downtown
Still don't see what you're looking for?
See all properties in Missouri City.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Missouri City

Explore lush parks and trails at Oyster Creek Park, where locals fish and spot wildlife along scenic boardwalks. Families gather for community festivals at Buffalo Run Park, while golfers enjoy Quail Valley's challenging courses just minutes from Houston.

See all hotels in Missouri City
A lake with lily pads and a forested shoreline.

Top Missouri City Hotel Reviews

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

8/10 Good
"There was a bug in are bed bed"
Caleb 2-night trip
Posted 4 hours ago
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
The Whitehall Houston

The Whitehall Houston

10/10 Excellent
"Great room! The hotel was beautiful, amazing bar and food! Loved the hospitality"
Bianca 1-night trip
Posted 4 hours ago
The Whitehall Houston
Grand Tuscany Hotel

Grand Tuscany Hotel

10/10 Excellent
"Great stay, but don’t have complementary anything for as much as it is per room."
Lorenzo 2-night trip
Posted 7 hours ago
Grand Tuscany Hotel
The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria

10/10 Excellent
"S"
Daniela 1-night trip
Posted 10 hours ago
The Royal Sonesta Houston Galleria
Marriott Marquis Houston

Marriott Marquis Houston

10/10 Excellent
"Nice Room...grat view"
Myron 1-night trip
Posted 14 hours ago
Marriott Marquis Houston
Omni Houston Hotel

Omni Houston Hotel

10/10 Excellent
"La piscina me encantó"
William 1-night trip
Posted 2 days ago
Omni Houston Hotel

Frequently asked questions

What are the best 4-star hotels in Missouri City?
If you're searching for deluxe comfort and loads of amenities during your Missouri City adventure, consider Houston Marriott Westchase. This sought-after 4-star hotel comes with a pillowtop mattress and concierge services. Hilton Houston Westchase also gets excellent reviews from Expedia guests. A spa tub and concierge services are among its conveniences.
How much does it cost to stay in a 4-star hotel in Missouri City?
With Expedia's handy search filters, locking in a superb deal on a 4-star hotel in Missouri City just got simpler. Start by entering your chosen arrival date and length of your getaway. Then sort the results by price and pick the option that best fits your style and budget.
  • Search for the lowest price from HK$2,310
What's the difference between 5-star and 4-star hotels in Missouri City?
If you decide to spend your holiday at a 4-star hotel in Missouri City, you'll typically find plenty of conveniences to keep you relaxed, such as a gym, pool and restaurant. You can experience top-quality service and upscale accommodation. Choose a 5-star hotel and you'll get a few more bells and whistles — think on-site spas, around-the-clock concierge and nightly turndown services. You'll most likely get additional amenities and first-class services at a 5-star retreat, though both are great options for luxury guests.

Explore a world of travel with Expedia