A large eye sculpture in a park surrounded by trees.

Northeast Missouri 4 Stars Hotels

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Check availability on Northeast Missouri 4 Star Hotels

Tonight
25 Sept - 26 Sept
Tomorrow
26 Sept - 27 Sept
This weekend
25 Sept - 27 Sept
Next weekend
2 Oct - 4 Oct

Our top choices for Northeast Missouri 4-star hotels

A buffet with fruits, pastries, and beverages.
A modern living room with a flat-screen TV, comfortable seating, and decorative items on shelves.
A spacious hotel lobby with multiple seating areas, a reception desk, and large windows offering a view of the cityscape.
The Renaissance Hotel with a modern architectural design, featuring a prominent central entrance and a symmetrical facade.

1. Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
Berkeley
United States
Anthony
HK$927
HK$1,084 total
includes taxes & fees
4 Oct - 5 Oct
Renaissance St. Louis Airport Hotel
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.
A reception desk with a wooden finish and the name "IDOL WOLF" on it.
A spacious lobby with a large spherical sculpture, a seating area, and a view of the outside through a large window.
A spacious lobby with multiple seating areas, a pool table, and artwork on the walls.

2. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
United States
Zane
HK$1,127
HK$1,357 total
includes taxes & fees
25 Oct - 26 Oct
21C Museum Hotel St Louis
A cozy lounge area with leather sofas, a fireplace, and a bar counter.
A traditional building with a stone facade, large windows, and outdoor seating area with wicker furniture.
An outdoor patio area with a pool, red umbrellas, and seating arrangements.
A modern building with a unique, curved roof structure.

3. The Cheshire

The Cheshire
Richmond Heights
United States
Matthew
HK$1,164
HK$1,382 total
includes taxes & fees
11 Oct - 12 Oct
The Cheshire
A modern outdoor lounge area with seating, a bar, and a view of a cityscape.
A modern living room with a sofa, coffee table, and bookshelves.
The exterior of the Clark & Bourbon hotel with a well-lit entrance, a marquee sign, and a landscaped planter area.
A modern bar area with a central fire feature, bar stools, and seating.

4. Live by Loews - St.Louis

Live by Loews - St.Louis
Downtown St. Louis
United States
Frank
HK$1,247
HK$1,483 total
includes taxes & fees
27 Sept - 28 Sept
Live by Loews - St.Louis
A modern hotel room with a large bed, a nightstand, a mirror, and a view of the city through arched windows.
A modern restaurant interior with high tables, chairs, and a central bar area.
A lobby with wooden paneling, a green wall, and two armchairs.
A bar area with wooden paneling, a counter, and multiple stools.

5. The Westin St. Louis

The Westin St. Louis
Downtown St. Louis
United States
Joanne
HK$1,028
HK$1,203 total
includes taxes & fees
18 Oct - 19 Oct
The Westin St. Louis
A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.
An outdoor patio with a brick fireplace, wicker furniture, and a dining table set with food and drinks.
A bar area with a marble counter, bar stools, and a variety of liquor bottles.
A restaurant with multiple dining tables and chairs, a bar area with shelves of bottles, and a large mirror above the bar.

6. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
Central West End
United States
Tosha
HK$1,169
HK$1,609 total
includes taxes & fees
4 Oct - 5 Oct
The Royal Sonesta Chase Park Plaza St. Louis
A long bar with multiple tables and chairs, wooden floors, and ornate chandeliers.
A large hotel with a prominent "RIVER CITY" sign.
A luxurious hotel lobby with a grand stage, elegant seating, and a large chandelier.
A casino with multiple gaming tables and slot machines.

7. River City Casino & Hotel

River City Casino & Hotel
St. Louis
United States
Ashley
HK$762
HK$1,001 total
includes taxes & fees
15 Oct - 16 Oct
River City Casino & Hotel
A rooftop terrace with outdoor seating, string lights, and a city skyline view.
A modern hotel room with a large window, a bathtub, and a unique eye-themed pillow.
A woman sitting on a green sofa in a modern lobby with a staircase and a large framed artwork on the wall.
A modern lounge area with a central cylindrical light fixture, white seating, and artwork on the walls.

8. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Grand Center
Canada
Timothy
HK$926
HK$1,092 total
includes taxes & fees
5 Oct - 6 Oct
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.
A bar area with multiple seating arrangements, a stage, and a chandelier.
A bakery display case with various pastries and cakes.
A grand lobby with a central chandelier, multiple levels, and rows of liquor bottles.

9. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
United States
Melissa
HK$1,171
HK$1,498 total
includes taxes & fees
12 Oct - 13 Oct
Ameristar Casino Resort and Spa
A multi-story hotel with a prominent 'Marriott' sign, featuring a classic architectural style with a red brick facade and large windows.
A spacious lobby with a high ceiling, a bar area, multiple seating arrangements, and a large screen displaying a sports event.
A grand hall with rows of chairs arranged for an event, a central floral arrangement, and a large chandelier.
A spacious interior with a central staircase, large windows, and hanging chandeliers.

10. Marriott St. Louis Grand

Marriott St. Louis Grand
Downtown St. Louis
United States
Andrew
HK$1,192
HK$1,418 total
includes taxes & fees
2 Oct - 3 Oct
Marriott St. Louis Grand
A rooftop restaurant with round tables, chairs, and a view of the city.
A rooftop terrace with seating areas, a decorative moon sculpture, and string lights.
A modern lobby with a staircase, seating area, and an exit sign.
A hotel with a prominent sign reading "MOONRISE."

11. Moonrise Hotel

Moonrise Hotel
Delmar Loop
United States
Nicole
HK$1,035
HK$1,231 total
includes taxes & fees
4 Oct - 5 Oct
Moonrise Hotel
A restaurant with round tables and chairs, a bar area, and a patterned ceiling.
A Drury Plaza Hotel with a large parking lot and multiple cars parked in front.
A spa bath with a sign indicating a capacity of 8 persons.
An indoor swimming pool with clear glass walls, a tiled floor, and a 'Step Down' sign.

12. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
Brentwood
United States
Jeana
HK$1,067
HK$1,266 total
includes taxes & fees
4 Oct - 5 Oct
Drury Plaza Hotel St. Louis Brentwood
A multi-story hotel with a prominent corner location, large windows, and a well-lit facade.
A bar area with a long counter, multiple stools, and a television mounted on the wall.
An indoor swimming pool area with lounge chairs, a small table, and potted plants.
A buffet area with various food items and a self-service station.

13. Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
Downtown St. Louis
United States
Karen
HK$894
HK$1,063 total
includes taxes & fees
11 Oct - 12 Oct
Embassy Suites by Hilton St. Louis Downtown
A modern lounge with a central fire feature, comfortable seating, and large windows offering a city view.
A bar area with wooden bar stools, a high counter, and a seating area with cushioned sofas and tables.
A modern bar area with high tables and stools, large windows with city views, and green chandeliers.
A rooftop terrace with a glass table, cushioned seating, and a view of the cityscape.

14. Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark
Downtown St. Louis
United States
Scott
HK$1,151
HK$1,369 total
includes taxes & fees
2 Oct - 3 Oct
Hilton St. Louis at the Ballpark
A brick building with a tower, large windows, and a fountain in the garden.
A spacious lobby with a chandelier, seating area, and a central table with a vase of flowers.
A grand lobby with a chandelier, a staircase, and a central table with a floral arrangement.
A pool area with lounge chairs and umbrellas, a clear blue pool, and a building with a dome in the background.

15. Hilton St. Louis Frontenac

Hilton St. Louis Frontenac
Frontenac
United States
Michael and Julie
HK$1,151
HK$1,341 total
includes taxes & fees
4 Oct - 5 Oct
Hilton St. Louis Frontenac
A rooftop pool area with multiple lounge chairs and umbrellas, surrounded by a modern building with large windows.
A cozy living room with a large TV, a fireplace, a Christmas tree, and a view of the city.
An outdoor seating area with modern furniture, a metal railing, and a view of surrounding buildings.
A long dining table set with candles, glassware, and white flowers, suggesting a formal dining experience.

16. Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
Clayton
United States
Steven
HK$1,193
HK$1,405 total
includes taxes & fees
4 Oct - 5 Oct
Le Méridien St. Louis Clayton
A modern dining area with round tables, orange chairs, and a decorative wall with pottery.
A swimming pool with a glass enclosure, a lounge area with orange chairs, and a view of a landscaped garden.
A modern lobby with seating areas, a reception desk, and a bar area.
A modern hotel lobby with a bar area, seating arrangements, and decorative lighting.

17. Marriott St. Louis Airport

Marriott St. Louis Airport
Edmundson
United States
Chris
HK$1,033
HK$1,233 total
includes taxes & fees
3 Oct - 4 Oct
Marriott St. Louis Airport
A bar area with a central bar, multiple stools, and a chandelier.
A grand lobby with a large chandelier, a bar area, and classical architecture.
A grand lobby with a bar area, chandeliers, and seating.
A grand lobby with a bar area, ornate chandeliers, and a staircase.

18. Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Downtown St. Louis
United States
Carol
HK$872
HK$1,037 total
includes taxes & fees
27 Sept - 28 Sept
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
A spacious lobby with high arched ceilings, ornate columns, and a central fountain.
A restaurant with tables and chairs, large windows, and a view of the street.
A spacious lobby with high ceilings, ornate green and gold detailing, and a central bar area.
A spacious lobby with a high arched ceiling, multiple seating areas, and a central decorative column.

19. St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
Downtown West
United States
Mirjana
HK$1,473
HK$1,752 total
includes taxes & fees
23 Oct - 24 Oct
St. Louis Union Station Hotel, Curio Collection by Hilton
A modern dining area with multiple tables and chairs, large windows with a city view, and contemporary lighting fixtures.
A hotel room with a sofa, a round table with a tray, a black dresser, and a large window with a view of a building.
A grand lobby with a high ceiling, ornate chandeliers, and a central seating area with blue upholstered chairs.
A rooftop pool area with lounge chairs and a clear view of the city skyline.

20. Hotel Saint Louis, Autograph Collection

Hotel Saint Louis, Autograph Collection
Downtown St. Louis
United States
Ryan
HK$1,325
HK$1,576 total
includes taxes & fees
27 Sept - 28 Sept
Hotel Saint Louis, Autograph Collection
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Northeast Missouri.
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

100 Carondelet Plaza St. Louis MO
HK$4,855
HK$5,667 total
11 Oct - 12 Oct
includes taxes & fees
9.2/10 Wonderful! (586 reviews)
The Ritz-Carlton, St. Louis
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Northeast Missouri

Great live music, sports teams and popular sights from St. Louis Zoo to St. Louis Union Station—explore Northeast Missouri, a family-friendly destination also known for its theatres.

See all hotels in Northeast Missouri
A large eye sculpture in a park surrounded by trees.
Photo by Andrew Hershfeld

Top Northeast Missouri Hotel Reviews

The Cheshire

The Cheshire

10/10 Excellent
"I got a room away from traffic sounds and it was great. Cute and quaint. Highly recommend to the business traveller like me."
natalie 2-night trip
Posted 4 hours ago
The Cheshire
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

10/10 Excellent
"Will definitely book again through them. Great price for the time I stayed and close to everything"
Emily 2-night trip
Posted 19 hours ago
Renaissance St. Louis Airport Hotel
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

8/10 Good
"Excellent roof top bar!!!"
michelle 1-night trip
Posted 1 day ago
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Live by Loews - St.Louis

Live by Loews - St.Louis

10/10 Excellent
"Amazing. Such a great atmosphere!"
Suzanne 1-night trip
Posted 2 days ago
Live by Loews - St.Louis

Frequently asked questions

What are the best 4-star hotels in Northeast Missouri?
You can find a variety of 4-star hotels in Northeast Missouri, including in St. Louis. St. Louis Union Station Hotel, Curio Collection by Hilton is an Expedia customer favourite here that offers premium bedding and concierge services. Another place that rates highly with travellers is The Last Hotel. Concierge services and a pillowtop mattress help make it their preferred choice.
How much does it cost to stay in a 4-star hotel in Northeast Missouri?
We can help you quickly locate the ideal 4-star hotel for your trip to Northeast Missouri. Use our filter tool to fine-tune your search by things like amenities, budget and star rating and get access to unbeatable deals in a couple of clicks.
  • Search for the lowest price from HK$5,667
What's the difference between 5-star and 4-star hotels in Northeast Missouri?
Give yourself the luxury treatment during your Northeast Missouri escape by checking in to a 4-star hotel. As well as featuring upscale accommodation, these properties are typically filled with amenities like large beds, complimentary bathrobes and more. A 5-star hotel will go the extra mile to make your trip an even more indulgent and unforgettable one. 24-hour front desk, luxurious spas and world-class dining are only the start of the exclusive services and conveniences you'll likely be able to enjoy.

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