Panama City Biomuseo Hotels: 2026 Limited-Time Hotel Deals @Expedia

A modern building with colorful geometric shapes and a clear blue sky.

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Our top choices for Biomuseo hotels

A spacious indoor courtyard with tiled flooring, multiple seating areas, and hanging plants.

A four-poster bed with a black and white bedspread, two bedside tables with lamps, and a robe hanging on a rack.

An open door revealing a balcony with a wrought iron railing, potted plants, and a window with a curtain.

A living room with a sofa, a coffee table with books, a chandelier, and a kitchen with wooden cabinets and granite countertops.

1. La Isabela Suites

San Felipe, 2.5 km from Biomuseo

David

HK$1,234

HK$1,358 total

includes taxes & fees

25 Oct - 26 Oct

A balcony with a table, chairs, and a view of a city skyline across a body of water.

A spacious living room with a high ceiling, large windows, and a decorative ceiling fan.

A hotel with a rooftop pool, lounge chairs, and a view of the sea.

A spacious lobby with high ceilings, modern furniture, and decorative lighting fixtures.

2. Sofitel Legend Casco Viejo, Panama City

San Felipe, 2.5 km from Biomuseo

Jose

HK$3,244

HK$3,569 total

includes taxes & fees

1 Nov - 2 Nov

A multi-story building with ornate balconies, large windows, and decorative moldings.

A luxurious room with ornate chandeliers, a large mirror, and a bar area with shelves of bottles.

A room with a white sofa, a wooden chair, a mirror, and a large window with curtains.

A spacious restaurant with high wooden ceilings, multiple tables and chairs, and a bar area with shelves of bottles and glasses.

3. Hotel Plaza Herrera

San Felipe, 2.4 km from Biomuseo

Christina

HK$1,830

HK$2,013 total

includes taxes & fees

7 Nov - 8 Nov

A restaurant with multiple dining tables, chairs, and a central water feature.

A modern living room with a sofa, a coffee table, and a TV mounted on the wall.

A historic building with ornate stonework and a balcony with plants.

A rooftop terrace with tables and chairs, a view of two white towers, and a building with a large window.

4. Hotel La Compañía Casco Antiguo

San Felipe, 2.4 km from Biomuseo

Carlos A

HK$2,192

HK$2,411 total

includes taxes & fees

25 Oct - 26 Oct

A restaurant interior with checkered flooring, wooden tables, wicker chairs, and hanging wicker lamps.

An outdoor patio with a checkered floor, a bar area with cushioned seating, and a large umbrella providing shade.

A multi-level interior with a checkered floor, wooden railings, and potted plants.

A rooftop terrace with a hot tub, wooden deck, outdoor seating, and a view of a cityscape including a clock tower.

5. Amarla Boutique Hotel Casco Viejo Adults Only

San Felipe, 2.5 km from Biomuseo

Shanae

HK$1,629

HK$1,792 total

includes taxes & fees

11 Nov - 12 Nov

A grand, illuminated building with a symmetrical facade, multiple balconies, and a prominent entrance.

A kitchen with a glass-top table, a coffee machine, wine glasses, and a bottle of wine.

A restaurant interior with a large indoor tree, tables, chairs, and a display of potted plants.

A spacious bedroom with a large bed, a chandelier, a bathroom with a bathtub, and a dining area.

6. La Concordia Boutique Hotel

San Felipe, 2.4 km from Biomuseo

Jadah

HK$1,783

HK$1,962 total

includes taxes & fees

6 Nov - 7 Nov

A spacious outdoor patio with wicker furniture, potted plants, and umbrellas providing shade.

A hotel with a covered entrance, multiple windows, and a balcony with plants.

A modern bar area with wooden bar stools, a black countertop, and a display of wine bottles.

A dimly lit restaurant with wooden decor, tables, and chairs arranged for dining.

7. Hotel San Felipe

San Felipe, 2.4 km from Biomuseo

RoseMarie

HK$1,228

HK$1,351 total

includes taxes & fees

28 Oct - 29 Oct

A spacious indoor area with high ceilings, large windows, and multiple dining tables.

A white building with multiple balconies, large windows, and decorative railings.

A spacious lobby with a tiled floor, large windows, and potted plants.

A restaurant with brick walls, arched windows, and a variety of seating arrangements including tables and chairs.

8. American Trade Hotel

San Felipe, 2.4 km from Biomuseo

Ashleigh-Ann

HK$1,925

HK$2,118 total

includes taxes & fees

2 Nov - 3 Nov

A spacious living area with a modern sofa, a wooden coffee table, and a staircase leading to an upper level.

A modern kitchen with white cabinets, a dining table with chairs, and a spiral staircase.

A bedroom with a large bed, a ceiling fan, and multiple windows.

A spiral staircase with a stone wall and a view of a living area with a fireplace.

9. Casa Lefevre By Wynwood House

San Felipe, 2.6 km from Biomuseo

Selam

HK$965

HK$1,277 total

includes taxes & fees

2 Nov - 3 Nov

A multi-story building with balconies, arched windows, and decorative railings.

A rooftop swimming pool with lounge chairs, potted plants, and a view of a city skyline including a prominent building with a dome.

A spacious lobby with a wooden staircase, multiple seating areas, and a reception desk.

A building with a balcony and a street view.

10. Central Hotel Panama Casco Viejo

San Felipe, 2.5 km from Biomuseo

Moejha

HK$1,716

HK$1,888 total

includes taxes & fees

23 Nov - 24 Nov

A modern indoor pool area with clear blue water, lounge chairs, and a wall of plants.

A balcony with a view of the sea, a table with a vase and a candle, and a chair.

A modern bedroom with a large window, a bed with white linens, a nightstand, and a painting on the wall.

A modern kitchen with a large window, a dining area with chairs, and a view of the city.

11. Casco View Life Residences

Santa Ana, 2.4 km from Biomuseo

Arshak Andrew

HK$656

HK$957 total

includes taxes & fees

29 Oct - 30 Oct

A hotel room with a bed, a desk with a computer, a chair, a mirror, and a staircase.

A balcony with a view of a city skyline, a river, and a large tree.

A spacious living area with a staircase leading to a loft, a large mirror, and a television.

A living room with a patterned sofa, a matching ottoman, a large mirror, and a staircase leading to an outdoor area.

12. Hotel Bardot Boutique

San Felipe, 2.5 km from Biomuseo

Luz

HK$743

HK$817 total

includes taxes & fees

22 Nov - 23 Nov

A rooftop bar with a city skyline view, outdoor seating, and a bar area with bottles and glasses.

A modern living room with a purple wall, two abstract paintings, a white sofa with colorful cushions, a wooden coffee table with books and bottles, and patterned floor tiles.

A restaurant interior with tables and chairs, decorative hanging lights, and a mural on the wall.

A hotel room with a large bed, a painting on the wall, a door, and a small table with a lamp.

13. Tantalo Hotel

San Felipe, 2.5 km from Biomuseo

Cynthia

HK$610

HK$670 total

includes taxes & fees

22 Nov - 23 Nov

A spacious living room with blue sofas, a marble coffee table, and framed pictures on the walls.

A bedroom with a large bed, white walls, and a view of a building through arched windows.

A blue building with arched windows and balconies, labeled 'Magnolia.'

A hotel room with a large bed, a TV, a balcony with a view of the outside, and a window with decorative ironwork.

14. Hotel Magnolia Boutique

San Felipe, 2.5 km from Biomuseo

Boris

HK$730

HK$803 total

includes taxes & fees

22 Nov - 23 Nov

An outdoor patio area with wicker furniture and glass-top tables, surrounded by lush greenery and a view of the interior.

A hotel room with a bed, a ceiling fan, a TV, a refrigerator, and a window with curtains.

A garden with a concrete pathway, various plants, and a birdcage.

A rectangular swimming pool with a tiled edge, surrounded by a tiled patio area.

15. The Balboa Inn

Balboa, 2.7 km from Biomuseo

Rhonda

HK$577

HK$635 total

includes taxes & fees

26 Oct - 27 Oct

A plate of pasta with grilled chicken and diced vegetables.

A formal dining area with round tables, white tablecloths, and blue lace borders.

A hotel room with a bed, a TV on a wooden cabinet, a nightstand with a lamp, and a view of the outdoors through a glass door.

A reception desk with three staff members, a green patterned wall, a wooden reception area, and a large plant.

16. Radisson Hotel Panama Canal

Amador, 1.5 km from Biomuseo

Si Ming

HK$663

HK$729 total

includes taxes & fees

4 Nov - 5 Nov

A modern bathroom with a glass shower enclosure, a herringbone wooden floor, and a stone wall feature.

A compact kitchen with a dining area, including a coffee maker, sink, and wooden chairs.

A modern bathroom with a glass shower enclosure, a wooden door, and a herringbone-patterned floor.

17. Corcho

San Felipe, 2.5 km from Biomuseo

Ashley

HK$748

HK$823 total

includes taxes & fees

31 Oct - 1 Nov

A modern kitchen with a dining area, large windows, and a view of the city.

A modern kitchen with a built-in oven and microwave, a living area with a sofa and ottomans, and a stone wall with a television.

A modern bedroom with a large bed, bedside tables, a nightstand, a dresser, a small table with a bowl, and a hanging light fixture.

A modern restaurant with a sushi bar, bar seating, and a mix of indoor and outdoor dining areas.

18. La Cuadra by Wynwood House

El Chorrillo, 2.3 km from Biomuseo

Lise Jane

HK$1,004

HK$1,340 total

includes taxes & fees

27 Oct - 28 Oct

A balcony with a view of a cityscape, including a river and a bridge.

A living room with a sofa, coffee table, TV, and artwork on the walls.

A high-rise building with a glass elevator shaft, a metal railing on the balcony, and a sign with the letters "OASIS".

A bedroom with a sloped ceiling, a bed with white bedding, a small wooden drying rack, a patterned rug, and an air conditioning unit.

19. Oasis Hotel

San Felipe, 2.5 km from Biomuseo

Charles

HK$466

HK$512 total

includes taxes & fees

12 Nov - 13 Nov

A balcony with a view of a marina and a hilly landscape.

A couple seated on wicker chairs with a view of a body of water and greenery in the background.

A modern hotel lobby with a reception desk, seating area, and a large window overlooking the city.

A couple in white robes on a bed with a champagne bottle and ice bucket.

20. The Beach House

Amador, 2.5 km from Biomuseo

JULIE

HK$540

HK$594 total

includes taxes & fees

1 Nov - 2 Nov

View all properties

Compare popular hotels close to Biomuseo

Property	Property class	Guest rating
La Isabela Suites	10.0 Exceptional 212 reviews	View
Sofitel Legend Casco Viejo, Panama City	9.8 Exceptional 765 reviews	View
Hotel Plaza Herrera	9.8 Exceptional 51 reviews	View
Hotel La Compañía Casco Antiguo	9.8 Exceptional 365 reviews	View
Amarla Boutique Hotel Casco Viejo Adults Only	9.6 Exceptional 146 reviews	View

Top Biomuseo Hotel Reviews

Hotel Riu Plaza Panama

10/10 Excellent

"Me gusta la ubica o, muy conveniente. El personal muy atento. El desayuno espectacular"

Central Hotel Panama Casco Viejo

8/10 Good

"Hotel is set in a beautiful square facing the cathedral. Staff all were very helpful. Prices for food and drinks are very reasonable for a hotel. My only complaint was at times the floor drains stunk in the bathroom. We didn’t let this spoil our week and would go back."

Hotel San Felipe

10/10 Excellent

"Loved our stay! Central, clean, wonderful staff"

Hotel Plaza Herrera

10/10 Excellent

"Perfect location in the middle of the historic old city. Excellent property condition (just renovated), spacious rooms. The staff was extremely helpful and friendly. A good breakfast to order is included at the downstairs restaurant. The only negative point is the absence of an elevator, so you will have to run up and down the stairs."

Hotel Caracas - Casco Viejo

8/10 Good

"Room was clean and very basic. No frills! The bed and pillows were comfortable and the AC worked well. Good location."

La Palma Experience

8/10 Good

"Recibimos buena atención, aunque se presentaron algunos inconvenientes como que el aire acondicionado no enfría a suficiente o que la presión de agua no llegaba a la habitacion, nos ofrecieron cambio de habitaciones lo cual nos permitió evaluar todas las opciones. Yo regreso, pero si me gustaría un menú más variado en sus desayunos, almuerzos y cenas."

w* | Upscale 2BR in Casco Antiguo w/ View

10/10 Excellent

"Liked the cleanliness, amenities and property condition. Property location was centrally located with easy access to restaurants, grocery store and more. Watching the Pacific tide was really amasing. It was really a nice stay."

Casa Love by Wynwood House

10/10 Excellent

"The unit we stayed in was large and fully equipped, with a balcony and a full kitchen. The building was secure and conveniently located within walking distance to everything in casco viejo. There are lots of shops and restaurants nearby and we felt mostly safe walking around. The only issue we had was that the code to our lockbox didn’t work when we arrived. However, we texted the property staff and they were able to give us another code that worked right away. The internet in the unit worked fine, but be sure to have a data plan or eSIM so that you can connect with the property and order Ubers, especially when you first get in, as the WiFi in the airport can be very spotty."

Casa La Costa By Wynwood House

10/10 Excellent

"Very nice place, clean and big, location is very good to walk around restaurants."

Other attractions near Biomuseo

Amador Causeway

9.0/10 (1,902 reviews)

You can learn about the history of Ancon with a visit to Amador Causeway. Stroll along the seaside or visit the shops in this vibrant area.

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Amador Convention Center

9.2/10 (23 reviews)

Learn about the events happening in Amador Convention Center during your trip to Ancon. While in this walkable area, you can savour the top-notch restaurants.

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Punta Culebra Nature Center

9.0/10 (14 reviews)

Enjoy an outing to Punta Culebra Nature Center during your stay in Ancon. Stroll along the seaside in this vibrant area or visit its top-notch restaurants.

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Maracana Stadium

8.0/10 (32 reviews)

Catch an event at Maracana Stadium during your trip to Panama City. Visit the shops and top-notch restaurants in this vibrant area.

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Smithsonian Tropical Research Institute Punta Culebra

9.2/10 (19 reviews)

You can spend time exploring the galleries in Smithsonian Tropical Research Institute Punta Culebra in Ancon. Amble around this vibrant area's seaside and enjoy its top-notch restaurants.

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Danilo Perez Foundation

Enjoy the student vibe at Danilo Perez Foundation as part of your travels around Panama City. Visit the shops and top-notch restaurants in this vibrant area.

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Plaza de Francia

10.0/10 (1 review)

You can learn about the history of Panama City when you stop by Plaza de Francia. Visit the shops and top-notch restaurants in this vibrant area.

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Mola Museum

You can spend time exploring the galleries in Mola Museum in Panama City. You can enjoy the bars while in the area.

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Frequently asked questions

What's the area like around Biomuseo?

Biomuseo is located in a vibrant area of Ancon known for its array of dining options and major shopping area. You'll find 1260 hotels and other accommodations within a few miles for a convenient home base.

What's the best hotel to stay near Biomuseo?

Radisson Hotel Panama Canal is one of the top choices for your stay based on our traveller data, and this hotel offers 2 outdoor pools and 2 restaurants. It's located just a short 0.9 mi (1.5 km) from Biomuseo. Another good choice is La Palma Experience, located just 0.7 mi (1.1 km) away.

How many hotels are there near Biomuseo?

Expedia has 1260 hotels and other accommodation options a few miles from Biomuseo.

If I need to cancel the hotel reservation for my stay near Biomuseo, will I receive a refund?

Yes, you'll find most room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to view the best deals near Biomuseo.

What can I see and do near Biomuseo?

Interoceanic Canal Museum, Mola Museum and Museum of History Panama feature a variety of fascinating exhibits to see while you're in town. Sights like Panama Canal Railway, Iglesia del Carmen and Paseo de Las Bovedas are must-sees while exploring the area. You can catch a show at National Theater, Anita Villalaz Theater and Amador Theater.

Panama City Biomuseo Hotels

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Biomuseo hotels

1. La Isabela Suites

2. Sofitel Legend Casco Viejo, Panama City

3. Hotel Plaza Herrera

4. Hotel La Compañía Casco Antiguo

5. Amarla Boutique Hotel Casco Viejo Adults Only

6. La Concordia Boutique Hotel

7. Hotel San Felipe

8. American Trade Hotel

9. Casa Lefevre By Wynwood House

10. Central Hotel Panama Casco Viejo

11. Casco View Life Residences

12. Hotel Bardot Boutique

13. Tantalo Hotel

14. Hotel Magnolia Boutique

15. The Balboa Inn

16. Radisson Hotel Panama Canal

17. Corcho

18. La Cuadra by Wynwood House

19. Oasis Hotel

20. The Beach House

Compare popular hotels close to Biomuseo

Top Biomuseo Hotel Reviews

Hotel Riu Plaza Panama

Central Hotel Panama Casco Viejo

Hotel San Felipe

Hotel Plaza Herrera

Hotel Caracas - Casco Viejo

La Palma Experience

w* | Upscale 2BR in Casco Antiguo w/ View

Casa Love by Wynwood House

Casa La Costa By Wynwood House

Other attractions near Biomuseo

Amador Causeway

Amador Convention Center

Punta Culebra Nature Center

Maracana Stadium

Smithsonian Tropical Research Institute Punta Culebra

Danilo Perez Foundation

Plaza de Francia

Mola Museum

Frequently asked questions