Best Commerce Hotels in 2026 from HK$518 - Fully Refundable Options

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Our top choices for Commerce hotels

A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.

A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.

A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.

1. Fairfield Inn & Suites by Marriott Cape Girardeau

Cape Girardeau

Carlos

HK$794

HK$895 total

includes taxes & fees

8 Oct - 9 Oct

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.

A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.

An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.

2. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Cape Girardeau

ELAINE

HK$777

HK$884 total

includes taxes & fees

29 Oct - 30 Oct

A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.

A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.

A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.

A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.

3. Drury Inn & Suites Cape Girardeau

Cape Girardeau

Teresa

HK$714

HK$805 total

includes taxes & fees

14 Oct - 15 Oct

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.

A Dear Tree Inn building with a covered entrance and a clear sky at dusk.

A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.

4. Pear Tree Inn Cape Girardeau West

Cape Girardeau

Elizabeth

HK$565

HK$637 total

includes taxes & fees

11 Oct - 12 Oct

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.

A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

5. Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

Sandra

HK$785

HK$885 total

includes taxes & fees

6 Oct - 7 Oct

A spacious dining area with high ceilings, large windows, and modern lighting fixtures.

A gym with exercise equipment, a treadmill, and a wall-mounted TV.

An outdoor patio with stone walls, wicker furniture, and large windows.

A large indoor swimming pool with clear blue water, surrounded by tiled flooring and blue walls.

6. Hampton Inn Cape Girardeau I 55 East

Cape Girardeau

Rebekah

HK$830

HK$936 total

includes taxes & fees

8 Oct - 9 Oct

A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.

A hotel room with two beds, a desk, a chair, and a view of the city.

A modern outdoor seating area with a fire feature, a stone wall, and a view of the sunset.

7. The Riverview

Cape Girardeau

Alyssa

HK$897

HK$1,012 total

includes taxes & fees

7 Oct - 8 Oct

A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.

A hotel room with two beds, a nightstand, a lamp, and a chair.

An outdoor patio with tables and chairs, a stone wall, and large windows.

8. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

Elaine

HK$634

HK$686 total

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with marble flooring, elegant seating, and a grand staircase.

A lobby with seating areas, a reception desk, and a bar.

A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.

A modern hotel lobby with a framed advertisement for breakfast at the new Bistro, a seating area with sofas and a coffee table, and a decorative mirror reflecting the space.

9. Courtyard by Marriott Cape Girardeau Downtown

Cape Girardeau

Kristin

HK$982

HK$1,112 total

includes taxes & fees

12 Oct - 13 Oct

A modern retail area with a display of local items and snacks.

A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.

A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.

10. Tru By Hilton Cape Girardeau

Cape Girardeau

Shannon

HK$701

HK$798 total

includes taxes & fees

8 Oct - 9 Oct

A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.

A hotel patio with a gazebo, outdoor seating, and a view of the road.

A hotel entrance with a large tree, a well-maintained garden with various plants and flowers, and a parking lot.

An indoor swimming pool with tiled flooring, a seating area with chairs, and a staircase leading to a door.

11. Candlewood Suites Cape Girardeau by IHG

Cape Girardeau

Samuel

HK$667

HK$796 total

includes taxes & fees

11 Oct - 12 Oct

A spacious lobby with large windows, comfortable seating, and a modern ceiling design.

A breakfast bar with coffee machines, a cereal dispenser, and a fruit display.

A hotel room with a bed, a dark sofa, an ottoman, a lamp, and artwork on the wall.

A room with large windows, two red upholstered chairs, a small table, and a potted plant.

12. Comfort Suites Jackson-Cape Girardeau

Jackson

VICTORIA

HK$594

HK$642 total

includes taxes & fees

25 Oct - 26 Oct

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

An outdoor seating area with sofas and planters, surrounded by a building with large windows and a brick wall.

A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.

A spacious lobby with a polished floor, seating areas, and modern lighting fixtures.

13. Drury Inn & Suites Sikeston, MO

Sikeston

Scott

HK$737

HK$848 total

includes taxes & fees

29 Oct - 30 Oct

A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.

A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.

A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.

A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'

14. Quality Inn Cape Girardeau North

Cape Girardeau

Danny

HK$467

HK$527 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.

A reception area with a counter, a flat-screen TV, and a window with blinds.

A restaurant with wooden cabinets, a refrigerator, and a counter with various items. There are tables and chairs for dining.

15. Super 8 by Wyndham Charleston/Sikeston East MO

Charleston

William

HK$467

HK$518 total

includes taxes & fees

4 Oct - 5 Oct

A building with a fountain and flower beds in front.

A hotel room with a beige sofa, two patterned armchairs, a ceiling fan, a flat-screen TV, and a window with curtains.

A hotel room with a large bed, two bedside tables with lamps, a chair, a small table, and a picture on the wall.

A reception area with a stone wall, wooden cabinets, and a sign for The Riverstone Hotel.

16. The Riverstone Hotel Charleston-Sikeston

Charleston

Kathleen

HK$522

HK$579 total

includes taxes & fees

14 Oct - 15 Oct

A hotel lobby with a reception desk, seating area, and a large window.

A Quality Inn hotel with a green sign, a covered outdoor area, and a parking lot.

A hotel room with a desk, chair, television, and a lamp.

A hotel room with two beds, a desk with a computer, a television, and a window with curtains.

17. Quality Inn Cairo I-57

Cairo

Santiago

HK$535

HK$594 total

includes taxes & fees

16 Oct - 17 Oct

A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.

A hotel room with a kitchenette, a bed, a dining table with chairs, a TV mounted on the wall, and a dresser.

A bathroom with a marble wall and a white bathtub.

A motel with multiple floors, a parking lot, and a staircase leading to the upper floors.

18. Town House Inn Cape Giradreau

Cape Girardeau

Joshua

HK$549

HK$642 total

includes taxes & fees

2 Oct - 3 Oct

A hotel room with a large bed, a desk, a television, and a bathroom visible through an open door.

A motel with a sign reading "Eagle Inn" and a parking lot with several cars.

A bathroom with a sink, mirror, towel rack, shower, and toilet.

A hotel room with two beds, a nightstand, a lamp, and a window with curtains.

19. Eagle Inn Charleston

Charleston

Jackson

HK$518

HK$575 total

includes taxes & fees

6 Oct - 7 Oct

A hotel room with two beds, a desk, a chair, a TV, and a mirror.

A reception area with a sofa, a small table, a trash bin, a microwave, and a book display.

A motel with a blue awning and a green 7-Eleven. It has a covered parking area and a two-story structure with a balcony.

A bathroom with a bathtub, toilet, and shower curtain.

20. Country Yard Inn and Suite

Sikeston

William

HK$481

HK$572 total

includes taxes & fees

10 Oct - 11 Oct

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Top Commerce Hotel Reviews

Drury Inn & Suites Sikeston, MO

10/10 Excellent

"EVERYONE was EXTREMELY FRIENDLY"

Quality Inn Cape Girardeau North

10/10 Excellent

"Great place great breakfast great room staff was great"

Candlewood Suites Cape Girardeau by IHG

10/10 Excellent

"trodo estubo excelente gracias por sus servicios"

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

10/10 Excellent

"Clean rooms. Nice breakfast. Very nice staff."

Drury Inn & Suites Cape Girardeau

10/10 Excellent

"Upgraded to a 2 room suite. Rey nice room lots of storage. Would definitely stay here again."

Hampton Inn Cape Girardeau I 55 East

8/10 Good

"Liked the cleanliness of the room, and every time my family left or when returning to our room the staff said hello. What I didn’t like there were a lot of ants in the room where the especially by the TV and desks."

Courtyard by Marriott Cape Girardeau Downtown

10/10 Excellent

"Very nice! Bed was comfortable and room had a very large bathroom and shower. Towels were thick and fluffy. Enjoyed having a bar downstairs with a fun friendly staff. Will stay there again when I’m coming through."

Cozy cabins on beautiful Horseshoe Lake

10/10 Excellent

"Super communication! . Accommodating. Nice people"

Town House Inn Cape Giradreau

8/10 Good

"The outside needed cleaning, but the room was very clean and well maintained."

More cheap stays in Commerce

Super 8 by Wyndham Charleston/Sikeston East MO

310 S Story St Charleston MO

HK$467

HK$518 total

4 Oct - 5 Oct

includes taxes & fees

Quality Inn Cape Girardeau North

2011 North Kingshighway Cape Girardeau MO

HK$467

HK$527 total

1 Nov - 2 Nov

includes taxes & fees

7/10 Good! (801 reviews)

Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy Cape Girardeau MO

HK$565

HK$637 total

11 Oct - 12 Oct

includes taxes & fees

Candlewood Suites Cape Girardeau by IHG

485 S Mount Auburn Rd Cape Girardeau MO

HK$667

HK$796 total

11 Oct - 12 Oct

includes taxes & fees

8/10 Very good! (1,000 reviews)

Tru By Hilton Cape Girardeau

2520 Veterans Memorial Dr Cape Girardeau MO

HK$701

HK$798 total

8 Oct - 9 Oct

includes taxes & fees

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

3253 William Street Cape Girardeau MO

HK$777

HK$884 total

29 Oct - 30 Oct

includes taxes & fees

Frequently asked questions

What's the best place to stay in Commerce?

Drury Plaza Hotel Cape Girardeau Conference Center, located 12.6 mi (20.3 km) from the heart of Commerce, is a top choice for your stay, based on our traveller data. Two other choices for your visit to the area are Pear Tree Inn Cape Girardeau West and The Riverview. See all available top hotels, or vacation rentals in Commerce.

What are some of the best holiday rentals that Commerce has to offer?

3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau: This holiday home rental outside of Commerce is equipped with a BBQ, air conditioning and laundry facilities to help you feel comfortable during your stay. Kitchen amenities include a dishwasher, a fridge and a stovetop. See all vacation rentals in Commerce.

If I need to cancel my hotel reservation in Commerce, will I receive a refund?

Yes! The majority of hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If your reservation is non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Commerce.

How is it to stay in Commerce?

Travellers to Commerce will find plenty to explore and enjoy. There are 88 hotels and other accommodation options in the surrounding area. Find out more about Commerce.

What should I see while I'm in Commerce?

A favourite place to visit is Mississippi River. You'll also find Century Casino & Hotel Cape Girardeau and Show Me Center in the area. Take a look at what more there is to see and do in Expedia's Commerce guide.

What's the seasonal weather in Commerce?

The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Commerce is 1491 mm.

Commerce hotels from HK$518

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Commerce

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Commerce hotels

1. Fairfield Inn & Suites by Marriott Cape Girardeau

2. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

3. Drury Inn & Suites Cape Girardeau

4. Pear Tree Inn Cape Girardeau West

5. Drury Plaza Hotel Cape Girardeau Conference Center

6. Hampton Inn Cape Girardeau I 55 East

7. The Riverview

8. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

9. Courtyard by Marriott Cape Girardeau Downtown

10. Tru By Hilton Cape Girardeau

11. Candlewood Suites Cape Girardeau by IHG

12. Comfort Suites Jackson-Cape Girardeau

13. Drury Inn & Suites Sikeston, MO

14. Quality Inn Cape Girardeau North

15. Super 8 by Wyndham Charleston/Sikeston East MO

16. The Riverstone Hotel Charleston-Sikeston

17. Quality Inn Cairo I-57

18. Town House Inn Cape Giradreau

19. Eagle Inn Charleston

20. Country Yard Inn and Suite

Top Commerce Hotel Reviews

Drury Inn & Suites Sikeston, MO

Quality Inn Cape Girardeau North

Candlewood Suites Cape Girardeau by IHG

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Drury Inn & Suites Cape Girardeau

Hampton Inn Cape Girardeau I 55 East

Courtyard by Marriott Cape Girardeau Downtown

Cozy cabins on beautiful Horseshoe Lake

Town House Inn Cape Giradreau

More cheap stays in Commerce

Super 8 by Wyndham Charleston/Sikeston East MO

Quality Inn Cape Girardeau North

Pear Tree Inn Cape Girardeau West

Candlewood Suites Cape Girardeau by IHG

Tru By Hilton Cape Girardeau

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Frequently asked questions

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