Photo by Jessica King

De Soto hotels from HK$441

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Our top choices for De Soto hotels

Super 8 by Wyndham Farmington

Super 8 by Wyndham Farmington
2.0 star property
Farmington
8.0 out of 10, Very good, (612)
"Clean, friendly staff, quiet"
United States
Stacy
The price is HK$410
HK$467 total
includes taxes & fees
1 Jan - 2 Jan 2026
Super 8 by Wyndham Farmington

Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO
2.5 star property
Farmington
8.0 out of 10, Very good, (1002)
"Room was clean , staff was friendly !"
United States
Sally
The price is HK$411
HK$467 total
includes taxes & fees
2 Jan - 3 Jan 2026
Baymont Inn and Suites by Wyndham Farmington, MO

La Quinta Inn & Suites by Wyndham Festus - St. Louis South

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
3.0 star property
Festus
8.0 out of 10, Very good, (893)
"Breakfast was great! Location right off interstate was perfect. The property is a little old."
United States
Mindy
The price is HK$720
HK$824 total
includes taxes & fees
4 Jan - 5 Jan 2026
La Quinta Inn & Suites by Wyndham Festus - St. Louis South

Quality Inn Farmington

Quality Inn Farmington
2.5 star property
Farmington
7.6 out of 10, Good, (862)
"The staff was friendly. We had a few issues with our stay but overall was good. Love there breakfast variety "
United States
edith
The price is HK$397
HK$474 total
includes taxes & fees
18 Jan - 19 Jan 2026
Quality Inn Farmington

Comfort Inn Festus - St Louis South

Comfort Inn Festus - St Louis South
2.5 star property
Festus
7.8 out of 10, Good, (911)
"Vary clean"
United States
George
The price is HK$588
HK$687 total
includes taxes & fees
29 Dec - 30 Dec
Comfort Inn Festus - St Louis South

Holiday Inn Express & Suites Farmington by IHG

Holiday Inn Express & Suites Farmington by IHG
2.5 star property
Farmington
8.6 out of 10, Excellent, (412)
"The staff was great!"
United States
Christopher
The price is HK$608
HK$1,924 total
includes taxes & fees
17 Jan - 18 Jan 2026
Holiday Inn Express & Suites Farmington by IHG

Hampton Inn Farmington

Hampton Inn Farmington
2.5 star property
Farmington
8.8 out of 10, Excellent, (519)
"Clean room, friendly staff."
United States
William
The price is HK$886
HK$1,009 total
includes taxes & fees
16 Jan - 17 Jan 2026
Hampton Inn Farmington

The Conner House B&B

The Conner House B&B
3.5 star property
Prairie du Rocher
10.0 out of 10, Exceptional, (19)
"Wonderful folks that work there. Nice b&b in a quiet , scenic area."
United States
Bradley
The price is HK$1,045
HK$1,160 total
includes taxes & fees
8 Jan - 9 Jan 2026
The Conner House B&B

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
2.0 star property
French Village
9.8 out of 10, Exceptional, (46)
"The cabin was cozy and very peaceful such a good experience "
United States
Russhell
The price is HK$692
HK$1,079 total
includes taxes & fees
5 Jan - 6 Jan 2026
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Drury Inn & Suites St. Louis Arnold

Drury Inn & Suites St. Louis Arnold
3.0 star property
Arnold
9.6 out of 10, Exceptional, (1000)
"Clean room, comfortable bed, free breakfast, dinner and drinks every night! We had a great stay, will definitely stay again!"
United States
Jacqueline
The price is HK$956
HK$1,105 total
includes taxes & fees
30 Dec - 31 Dec
Drury Inn & Suites St. Louis Arnold

Super 8 by Wyndham Bonne Terre

Super 8 by Wyndham Bonne Terre
2.0 star property
Bonne Terre
7.0 out of 10, Good, (540)
"The room was spacious and very clean. The parking was free and close to the entrance, excellent water pressure for the shower, and the staff was friendly and professional."
United States
Raymond
The price is HK$403
HK$441 total
includes taxes & fees
5 Jan - 6 Jan 2026
Super 8 by Wyndham Bonne Terre

Crown Pointe Lodge, BW Signature Collection

Crown Pointe Lodge, BW Signature Collection
2.5 star property
Farmington
9.0 out of 10, Wonderful, (577)
"Clean, friendly staff enjoyed the stay"
United States
John
The price is HK$855
HK$974 total
includes taxes & fees
28 Dec - 29 Dec
Crown Pointe Lodge, BW Signature Collection

Motel 6 Bonne Terre, MO

Motel 6 Bonne Terre, MO
2.0 star property
Bonne Terre
7.0 out of 10, Good, (27)
"Clean, was perfect for my one night stay in the area"
United States
Dave
The price is HK$455
HK$498 total
includes taxes & fees
29 Dec - 30 Dec
Motel 6 Bonne Terre, MO

Baymont by Wyndham Festus

Baymont by Wyndham Festus
3.0 star property
Festus
6.8 out of 10, (923)
"Room was clean and comfortable for an overnight stay"
United States
Jack
The price is HK$630
HK$720 total
includes taxes & fees
29 Dec - 30 Dec
Baymont by Wyndham Festus

Corner George Inn Bed & Breakfast

Corner George Inn Bed & Breakfast
2.5 star property
Maeystown
9.0 out of 10, Wonderful, (154)
"Hosts were excellent, very quiet and the breakfast was wonderful"
United States
Mark
The price is HK$1,000
HK$1,110 total
includes taxes & fees
1 Jan - 2 Jan 2026
Corner George Inn Bed & Breakfast

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
2.5 star property
Festus
9.4 out of 10, Exceptional, (702)
"Clean, spotless, great room, front desk staff was excellent! Parking great!"
United States
Rick
The price is HK$1,019
HK$1,165 total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Arnold
2.5 star property
Arnold
9.4 out of 10, Exceptional, (1001)
"Always very pleasant staff!"
United States
Julie
The price is HK$700
HK$809 total
includes taxes & fees
30 Dec - 31 Dec
Pear Tree Inn St. Louis Arnold

Tiny Houses of French Village

Tiny Houses of French Village
2.5 star property
French Village
10.0 out of 10, Exceptional, (3)
"Charming property with a space for everything and everything in its place. Would not hesitate to recommend or stay again."
United States
Norma
Tiny Houses of French Village

YMCA Trout Lodge

YMCA Trout Lodge
2.0 star property
Potosi
10.0 out of 10, Exceptional, (1)
"When checking in the staff was great. Stay was relaxing. Only downside was the carpeted floors in the bunk bed room. Appears the carpet under the beds has not been vacuumed in a bit with the dust, dead bugs and cobwebs. Had my wife not dropped an ear ring, would never have noticed so not a big thing. "
United States
Leonard
The price is HK$1,177
HK$1,263 total
includes taxes & fees
29 Dec - 30 Dec
YMCA Trout Lodge

WoodSpring Suites St. Louis Arnold

WoodSpring Suites St. Louis Arnold
2.5 star property
Arnold
6.0 out of 10, (442)
"Location was great as was staff"
United States
Randall
The price is HK$630
HK$728 total
includes taxes & fees
28 Dec - 29 Dec
WoodSpring Suites St. Louis Arnold
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Kayaking down the Big River on a fall day!
Photo by Jessica King
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Top De Soto Hotel Reviews

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Frequently asked questions

Where is the best place to stay in De Soto?
Baymont Inn and Suites by Wyndham Farmington, MO, located 26 mi (41.8 km) from the heart of De Soto, is a top choice for your stay, based on our traveller data. Other good options for your trip to the area are Pear Tree Inn St. Louis Arnold and Drury Inn & Suites St. Louis Arnold. See all available top hotels, or vacation rentals in De Soto.
What are some of the best holiday rentals that De Soto has to offer?
Goforth into Nature, a charming 1-bdrm home in the quiet Bloomsdale countryside.: This holiday home rental outside De Soto is located in a rural location, and has a patio, a garden and a BBQ to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge and a stovetop. You can relax into your holiday with a selection of games and 1 hot tub. See all vacation rentals in De Soto.
If I need to cancel my hotel reservation in De Soto, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in De Soto.
What's the best dog-friendly accommodation option in De Soto?
What are some accommodation options with pools in De Soto?
Baymont Inn and Suites by Wyndham Farmington, MO: Features buffet, a seasonal outdoor pool and free self parking. Pear Tree Inn St. Louis Arnold and Drury Inn & Suites St. Louis Arnold are a couple of other choices that offer an on-site pool. View all hotels with pools in De Soto.
What is staying in De Soto like?
Visitors can enjoy all that De Soto has to offer, including its restaurants. In De Soto, there are 6 hotels and other accommodation options to choose from. Find out more about De Soto.
What should I see while I'm in De Soto?
Natural beauty is on display at Sunrise Lake Beach, Big River and Big Lake. A couple of additional sights to add to your itinerary are Washington State Park and Redfield's Flea Market. Take a look at what more there is to see and do in Expedia's De Soto guide.
What's the seasonal weather like in De Soto?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for De Soto is 1181 mm.

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