Defiance hotels from HK$550

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Our top choices for Defiance hotels

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
Fenton
8.0 out of 10, Very good, (1,121 reviews)
"Great room, great people, great breakfast "
United States
Jaiden
The price is HK$698
HK$806 total
includes taxes & fees
10 Mar - 11 Mar
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Quality Inn Foristell

Quality Inn Foristell
2.5 star property
Foristell
8.2 out of 10, Very good, (948 reviews)
" Clean room friendly staff easy access"
United States
Steve
The price is HK$532
HK$601 total
includes taxes & fees
22 Mar - 23 Mar
Quality Inn Foristell

Baymont by Wyndham Warrenton

Baymont by Wyndham Warrenton
2.5 star property
Warrenton
7.4 out of 10, Good, (1,003 reviews)
"Nice place and nice people "
United States
Columbus
The price is HK$640
HK$731 total
includes taxes & fees
11 Mar - 12 Mar
Baymont by Wyndham Warrenton

Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66
3.0 star property
Fenton
8.0 out of 10, Very good, (1,152 reviews)
"Clean rooms, quiet, AC worked great and good breakfast "
United States
Karen
The price is HK$618
HK$714 total
includes taxes & fees
10 Mar - 11 Mar
Wingate by Wyndham St. Louis/Fenton Route 66

WoodSpring Suites St Peters-OFallon

WoodSpring Suites St Peters-OFallon
2.5 star property
St. Peters
9.0 out of 10, Wonderful, (48 reviews)
"Super clean , quiet place "
United States
Phoenix
The price is HK$696
HK$824 total
includes taxes & fees
10 Mar - 11 Mar
WoodSpring Suites St Peters-OFallon

Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive
2.5 star property
O'Fallon
9.0 out of 10, Wonderful, (1,011 reviews)
"Friendly staff, clean room, comfy bed, excellent breakfast buffet."
United States
Kathy
The price is HK$620
HK$731 total
includes taxes & fees
11 Mar - 12 Mar
Sleep Inn & Suites O'Fallon MO - Technology Drive

The Wildwood Hotel

The Wildwood Hotel
3.5 star property
Wildwood
9.2 out of 10, Wonderful, (1,636 reviews)
"Clean room and great breakfast "
United States
Shawn
The price is HK$760
HK$886 total
includes taxes & fees
10 Mar - 11 Mar
The Wildwood Hotel

Best Western Plus Fenton

Best Western Plus Fenton
2.5 star property
Fenton
9.2 out of 10, Wonderful, (222 reviews)
"Stay was great, and the pool was perfect for my daughter and her friend. Wonderful spot for an easy "stay cation" with the girls. "
United States
Melissa
The price is HK$713
HK$824 total
includes taxes & fees
10 Mar - 11 Mar
Best Western Plus Fenton

Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
2.5 star property
St. Charles
8.4 out of 10, Very good, (1,008 reviews)
"Great hotel for the money"
United States
Jere
The price is HK$681
HK$783 total
includes taxes & fees
15 Mar - 16 Mar
Comfort Suites St Charles - St Louis

Best Western Plus Washington Hotel

Best Western Plus Washington Hotel
2.5 star property
Washington
9.2 out of 10, Wonderful, (664 reviews)
"Clean room and hotel with a nice breakfast, have stayed here two times while visiting family."
United States
Brooks
The price is HK$1,009
HK$1,149 total
includes taxes & fees
10 Mar - 11 Mar
Best Western Plus Washington Hotel

Super 8 by Wyndham St Charles

Super 8 by Wyndham St Charles
2.0 star property
St. Charles
8.0 out of 10, Very good, (1,005 reviews)
"Great place to stay for the $$$"
United States
Kale
The price is HK$625
HK$718 total
includes taxes & fees
15 Mar - 16 Mar
Super 8 by Wyndham St Charles

Quality Inn Near Six Flags St. Louis

Quality Inn Near Six Flags St. Louis
2.5 star property
Pacific
8.4 out of 10, Very good, (366 reviews)
"Excellent staff & very clean room"
United States
Karen
The price is HK$774
HK$887 total
includes taxes & fees
10 Mar - 11 Mar
Quality Inn Near Six Flags St. Louis

Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters
3.0 star property
St. Peters
9.4 out of 10, Exceptional, (1,006 reviews)
"Comfortable room. Quiet even though next to interstate. Excellent food "
United States
Geo
The price is HK$860
HK$989 total
includes taxes & fees
15 Mar - 16 Mar
Drury Inn & Suites St. Louis St. Peters

Hampton Inn St. Louis Wentzville

Hampton Inn St. Louis Wentzville
2.5 star property
Wentzville
9.0 out of 10, Wonderful, (666 reviews)
"Prompt service, quick check in. "
United States
Emily
The price is HK$932
HK$1,067 total
includes taxes & fees
15 Mar - 16 Mar
Hampton Inn St. Louis Wentzville

Holiday Inn Express & Suites Wentzville St Louis West by IHG

Holiday Inn Express & Suites Wentzville St Louis West by IHG
2.5 star property
Wentzville
9.4 out of 10, Exceptional, (875 reviews)
"Beautiful hotel, friendly staff, good breakfast."
United States
Erika
The price is HK$1,056
HK$1,258 total
includes taxes & fees
15 Mar - 16 Mar
Holiday Inn Express & Suites Wentzville St Louis West by IHG

Holiday Inn St. Louis West Six Flags by IHG

Holiday Inn St. Louis West Six Flags by IHG
3.0 star property
Eureka
9.0 out of 10, Wonderful, (1,001 reviews)
"Clean rooms and kids really enjoyed the pool area."
United States
VeAnn
The price is HK$954
HK$1,112 total
includes taxes & fees
8 Apr - 9 Apr
Holiday Inn St. Louis West Six Flags by IHG

Fairfield Inn & Suites Wentzville

Fairfield Inn & Suites Wentzville
3.0 star property
Wentzville
9.0 out of 10, Wonderful, (659 reviews)
"Hotel staff was friendly and room was very clean "
United States
Danielle
The price is HK$1,072
HK$1,227 total
includes taxes & fees
15 Mar - 16 Mar
Fairfield Inn & Suites Wentzville

River Sirens Hotel

River Sirens Hotel
2.5 star property
Washington
9.8 out of 10, Exceptional, (191 reviews)
"The room was amazing!!! Would definitely stay again "
United States
Katharine
River Sirens Hotel

Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters
2.5 star property
St. Charles
8.0 out of 10, Very good, (1,003 reviews)
"Great location and friendly staff "
United States
Heather
The price is HK$827
HK$951 total
includes taxes & fees
29 Mar - 30 Mar
Hampton Inn St. Charles St. Peters

Cedar Creek

Cedar Creek
3.0 star property
New Haven
9.0 out of 10, Wonderful, (265 reviews)
"We got a surprise upgrade to our room. The cottage was beautiful and clean. The staff was perfect."
United States
Joan
Cedar Creek
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Defiance attractions

Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

A covered bridge at the Historic Daniel Boone Home Park in Defiance, Missouri

Top Defiance Hotel Reviews

More cheap stays in Defiance

Frequently asked questions

What's the best place to stay in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham, located 17.9 mi (28.8 km) from the heart of Defiance, is a top choice for your stay, based on our traveller data. Two other options for your visit to the area are The Wildwood Hotel and Ameristar Casino Resort and Spa. See all available top hotels, or vacation rentals in Defiance.
What are some of the best holiday rentals that Defiance has to offer?
St. Charles 1860's Gem - Sleeps 6!: This holiday home rental outside of Defiance is located on a river, and has a garden, a selection of books and air conditioning to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge and a stovetop. See all vacation rentals in Defiance.
If I need to cancel my hotel reservation in Defiance, will I receive a refund?
Yes! The majority of room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.
What are some accommodation options with pools in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham: Features an indoor pool, an outdoor pool and buffet. The Wildwood Hotel and Ameristar Casino Resort and Spa are two additional hotels with an on-site pool. View all hotels with pools in Defiance.
How is it staying in Defiance?
Visitors can enjoy all that Defiance has to offer, including the wineries and parks. Top sights in the area include St. Louis Union Station and Busch Stadium. In Defiance, there are 19 hotels and other accommodation options to choose from. Find out more about Defiance.
What should I do while I'm visiting Defiance?
Natural beauty is on display at August A. Busch Memorial Conservation Area, Missouri River and Matson Hill Park Trailhead. A couple of additional sights to add to your itinerary are Chandler Hill Vineyards and Sugar Creek Winery. Take a look at what more there is to see and do in Expedia's Defiance guide.
What's the weather like in Defiance?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.

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