Defiance hotels from HK$579

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Our top choices for Defiance hotels

Super 8 by Wyndham Union

Super 8 by Wyndham Union
2.0 star property
Union
8.2 out of 10, Very good, (647 reviews)
"Pet friendly "
United States
Theresa
The price is HK$663
HK$732 total
includes taxes & fees
4 May - 5 May
Super 8 by Wyndham Union

Baymont by Wyndham Warrenton

Baymont by Wyndham Warrenton
2.5 star property
Warrenton
7.6 out of 10, Good, (1,005 reviews)
"Excellent place to stay!"
United States
Steven
The price is HK$580
HK$662 total
includes taxes & fees
10 May - 11 May
Baymont by Wyndham Warrenton

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
Fenton
8.0 out of 10, Very good, (1,245 reviews)
"Nice room, comfortable bed, good breakfast."
United States
John
The price is HK$699
HK$808 total
includes taxes & fees
17 May - 18 May
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Quality Inn Foristell

Quality Inn Foristell
2.5 star property
Foristell
8.2 out of 10, Very good, (973 reviews)
"Good breakfast. Parking Good. "
United States
Nicholas
The price is HK$670
HK$757 total
includes taxes & fees
3 May - 4 May
Quality Inn Foristell

WoodSpring Suites St Peters-OFallon

WoodSpring Suites St Peters-OFallon
2.5 star property
St. Peters
8.6 out of 10, Excellent, (97 reviews)
"Nice hotel with good staff."
United States
Michael
The price is HK$609
HK$722 total
includes taxes & fees
25 May - 26 May
WoodSpring Suites St Peters-OFallon

Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66
3.0 star property
Fenton
7.8 out of 10, Good, (1,199 reviews)
"This place is always clean and staff is always friendly. I stay here we very week for work "
United States
Steve
The price is HK$666
HK$769 total
includes taxes & fees
3 May - 4 May
Wingate by Wyndham St. Louis/Fenton Route 66

Drury Inn & Suites Southwest St. Louis

Drury Inn & Suites Southwest St. Louis
3.0 star property
Valley Park
9.6 out of 10, Exceptional, (1,002 reviews)
"Very nice, well maintained hotel with generous size rooms and great amenities. "
United States
William
The price is HK$870
HK$1,017 total
includes taxes & fees
10 May - 11 May
Drury Inn & Suites Southwest St. Louis

Hampton Inn St. Louis Wentzville

Hampton Inn St. Louis Wentzville
2.5 star property
Wentzville
9.0 out of 10, Wonderful, (698 reviews)
"Good location, clean and friendly staff. "
United States
Michelle
The price is HK$1,122
HK$1,284 total
includes taxes & fees
10 May - 11 May
Hampton Inn St. Louis Wentzville

Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive
2.5 star property
O'Fallon
9.0 out of 10, Wonderful, (1,008 reviews)
"This was one of our best stays ever nice hot breakfast. Clean room nice staff will stay again "
United States
Lavania
The price is HK$657
HK$774 total
includes taxes & fees
4 May - 5 May
Sleep Inn & Suites O'Fallon MO - Technology Drive

Best Western Plus Washington Hotel

Best Western Plus Washington Hotel
2.5 star property
Washington
9.2 out of 10, Wonderful, (675 reviews)
"Breakfast was good, as hotel breakfasts go. Room was clean, friendly and helpful staff. Had a good stay overall."
United States
Raymond
The price is HK$1,011
HK$1,151 total
includes taxes & fees
3 May - 4 May
Best Western Plus Washington Hotel

Super 8 by Wyndham Warrenton

Super 8 by Wyndham Warrenton
2.0 star property
Warrenton
7.4 out of 10, Good, (644 reviews)
"The parking was easy, the room was verry clean."
United States
Gary
The price is HK$413
HK$472 total
includes taxes & fees
4 May - 5 May
Super 8 by Wyndham Warrenton

Best Western Plus Fenton

Best Western Plus Fenton
2.5 star property
Fenton
9.2 out of 10, Wonderful, (274 reviews)
"Simply love it better than 4 star hotels"
United States
Srinivas
The price is HK$777
HK$897 total
includes taxes & fees
24 May - 25 May
Best Western Plus Fenton

The Wildwood Hotel

The Wildwood Hotel
3.5 star property
Wildwood
9.2 out of 10, Wonderful, (1,631 reviews)
"The hotel is really nice and close to good restaurants."
United States
Jackie
The price is HK$691
HK$805 total
includes taxes & fees
4 May - 5 May
The Wildwood Hotel

Quality Inn Near Six Flags St. Louis

Quality Inn Near Six Flags St. Louis
2.5 star property
Pacific
8.4 out of 10, Very good, (373 reviews)
"Excellent customer service. Beautiful hotel. Comfy bed with fluffy pillows. Great breakfast!"
United States
Christel
The price is HK$811
HK$929 total
includes taxes & fees
3 May - 4 May
Quality Inn Near Six Flags St. Louis

Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
2.5 star property
St. Charles
8.4 out of 10, Very good, (1,004 reviews)
"Great stay"
United States
Maurice
The price is HK$733
HK$843 total
includes taxes & fees
10 May - 11 May
Comfort Suites St Charles - St Louis

Holiday Inn Express & Suites St Peters by IHG

Holiday Inn Express & Suites St Peters by IHG
2.5 star property
St. Peters
9.2 out of 10, Wonderful, (405 reviews)
"Great breakfast nice bed"
United States
Carl
The price is HK$862
HK$1,039 total
includes taxes & fees
10 May - 11 May
Holiday Inn Express & Suites St Peters by IHG

Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters
3.0 star property
St. Peters
9.4 out of 10, Exceptional, (1,006 reviews)
"Great location and clean hotel!"
United States
Admir
The price is HK$932
HK$1,072 total
includes taxes & fees
19 May - 20 May
Drury Inn & Suites St. Louis St. Peters

Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters
2.5 star property
St. Charles
8.0 out of 10, Very good, (1,007 reviews)
"Breakfast menu was adequate. Staff was pleasant and helpful, the room was very clean Did not use the hot tub."
United States
Rich
The price is HK$893
HK$1,026 total
includes taxes & fees
25 May - 26 May
Hampton Inn St. Charles St. Peters

Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles
3.0 star property
St. Charles
9.6 out of 10, Exceptional, (1,007 reviews)
"Everything about this hotel was great "
United States
Delovin Choice
The price is HK$1,136
HK$1,317 total
includes taxes & fees
3 May - 4 May
Drury Plaza Hotel St. Louis St. Charles

Fairfield Inn & Suites Wentzville

Fairfield Inn & Suites Wentzville
3.0 star property
Wentzville
9.0 out of 10, Wonderful, (672 reviews)
"Property was nice, easy check-in, nice breakfast, room was clean."
United States
Doris
The price is HK$1,038
HK$1,188 total
includes taxes & fees
24 May - 25 May
Fairfield Inn & Suites Wentzville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Defiance attractions

Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

A covered bridge at the Historic Daniel Boone Home Park in Defiance, Missouri

Top Defiance Hotel Reviews

More cheap stays in Defiance

Frequently asked questions

What's the best place to stay in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham, located 17.9 mi (28.8 km) from the heart of Defiance, is a top choice for your stay, based on our traveller data. Two other options for your visit to the area are Hollywood Casino & Hotel St. Louis and Ameristar Casino Resort and Spa. See all available top hotels, or vacation rentals in Defiance.
What are some of the best holiday rentals that Defiance has to offer?
St. Charles 1860's Gem - Sleeps 6!: This holiday home rental outside of Defiance is located on a river, and has a garden, a selection of books and air conditioning to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge and a stovetop. See all vacation rentals in Defiance.
If I need to cancel my hotel reservation in Defiance, will I receive a refund?
Yes! The majority of room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.
What are some accommodation options with pools in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham: Features an indoor pool, an outdoor pool and buffet. Ameristar Casino Resort and Spa and La Quinta Inn & Suites by Wyndham St. Louis Westport are two additional hotels with an on-site pool. View all hotels with pools in Defiance.
How is it staying in Defiance?
Visitors can enjoy all that Defiance has to offer, including the wineries and parks. Top sights in the area include St. Louis Union Station, Busch Stadium and Gateway Arch. In Defiance, there are 19 hotels and other accommodation options to choose from. Find out more about Defiance.
What should I do while I'm visiting Defiance?
Natural beauty is on display at August A. Busch Memorial Conservation Area, Missouri River and Matson Hill Park Trailhead. A couple of additional sights to add to your itinerary are Chandler Hill Vineyards and Sugar Creek Winery. Take a look at what more there is to see and do in Expedia's Defiance guide.
What's the weather like in Defiance?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.

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