A covered bridge at the Historic Daniel Boone Home Park in Defiance, Missouri

Defiance hotels from HK$591

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Our top choices for Defiance hotels

Quality Inn Foristell

Quality Inn Foristell
2.5 star property
Foristell
8.2 out of 10, Very good, (1,011 reviews)
"Staff was helpful, area was easy tp navigate. Place was great for the price"
United States
Ryan
The price is HK$656
HK$741 total
includes taxes & fees
28 Jun - 29 Jun
Quality Inn Foristell

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
Fenton
7.8 out of 10, Good, (1,366 reviews)
"Will definitely stay again!"
United States
Trevor
The price is HK$779
HK$900 total
includes taxes & fees
16 Jun - 17 Jun
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Super 8 by Wyndham St Charles

Super 8 by Wyndham St Charles
2.0 star property
St. Charles
8.0 out of 10, Very good, (1,018 reviews)
"Great location, of staying away from busy intersections!!"
United States
David
The price is HK$659
HK$758 total
includes taxes & fees
23 Jun - 24 Jun
Super 8 by Wyndham St Charles

WoodSpring Suites St Peters-OFallon

WoodSpring Suites St Peters-OFallon
2.5 star property
St. Peters
8.6 out of 10, Excellent, (158 reviews)
"The location was great"
United States
DeLante
The price is HK$575
HK$681 total
includes taxes & fees
8 Jul - 9 Jul
WoodSpring Suites St Peters-OFallon

Economy Inn Wentzville

Economy Inn Wentzville
2.0 star property
Wentzville
6.4 out of 10, (546 reviews)
"Room was clean but basic"
United States
James
The price is HK$548
HK$622 total
includes taxes & fees
16 Jun - 17 Jun
Economy Inn Wentzville

Best Western Plus Fenton

Best Western Plus Fenton
2.5 star property
Fenton
9.2 out of 10, Wonderful, (333 reviews)
"Was a good place to stay"
Canada
Blake
The price is HK$715
HK$825 total
includes taxes & fees
5 Jul - 6 Jul
Best Western Plus Fenton

Baymont by Wyndham Warrenton

Baymont by Wyndham Warrenton
2.5 star property
Warrenton
7.6 out of 10, Good, (1,002 reviews)
"Excellent place to stay!"
United States
Steven
The price is HK$640
HK$731 total
includes taxes & fees
29 Jun - 30 Jun
Baymont by Wyndham Warrenton

Comfort Inn & Suites St. Louis - O'Fallon

Comfort Inn & Suites St. Louis - O'Fallon
2.5 star property
O'Fallon
7.6 out of 10, Good, (1,005 reviews)
"Quiet and wood's surroundings nice place"
United States
Matthew
The price is HK$717
HK$846 total
includes taxes & fees
14 Jul - 15 Jul
Comfort Inn & Suites St. Louis - O'Fallon

Holiday Inn Express & Suites Wentzville St Louis West by IHG

Holiday Inn Express & Suites Wentzville St Louis West by IHG
2.5 star property
Wentzville
9.4 out of 10, Exceptional, (925 reviews)
"We have stay here before and requested to stay again. Great hotel."
United States
Steve
The price is HK$1,167
HK$1,387 total
includes taxes & fees
5 Jul - 6 Jul
Holiday Inn Express & Suites Wentzville St Louis West by IHG

Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66
3.0 star property
Fenton
7.8 out of 10, Good, (1,256 reviews)
"Clean room, good staff, breakfast OK."
United States
MARK
The price is HK$699
HK$808 total
includes taxes & fees
16 Jun - 17 Jun
Wingate by Wyndham St. Louis/Fenton Route 66

The Wildwood Hotel

The Wildwood Hotel
3.5 star property
Wildwood
9.2 out of 10, Wonderful, (1,664 reviews)
"Very nice hotel for the price! Would definitely stay there again in the future!"
United States
Lori
The price is HK$691
HK$805 total
includes taxes & fees
14 Jul - 15 Jul
The Wildwood Hotel

Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters
2.5 star property
St. Charles
8.0 out of 10, Very good, (1,011 reviews)
"Good staff "
United States
Solomon
The price is HK$893
HK$1,026 total
includes taxes & fees
5 Jul - 6 Jul
Hampton Inn St. Charles St. Peters

Super 8 by Wyndham O'Fallon MO/St. Louis Area

Super 8 by Wyndham O'Fallon MO/St. Louis Area
2.0 star property
O'Fallon
7.0 out of 10, Good, (1,005 reviews)
"Clean room, friendly staff"
United States
Shelly
The price is HK$546
HK$644 total
includes taxes & fees
21 Jun - 22 Jun
Super 8 by Wyndham O'Fallon MO/St. Louis Area

Cedar Creek

Cedar Creek
3.0 star property
New Haven
9.0 out of 10, Wonderful, (270 reviews)
"Nice quiet stay for nearby wedding. "
United States
joan
The price is HK$1,154
HK$1,234 total
includes taxes & fees
26 Jun - 27 Jun
Cedar Creek

River Sirens Hotel

River Sirens Hotel
2.5 star property
Washington
9.8 out of 10, Exceptional, (202 reviews)
"We love the theme, the hotel was clean and we love that we could walk down to the alley and play arcade games and have a beer and we love the breakfast voucher as well. What a neat place to stay."
United States
Natalie
The price is HK$1,054
HK$1,200 total
includes taxes & fees
21 Jun - 22 Jun
River Sirens Hotel

Drury Inn & Suites Southwest St. Louis

Drury Inn & Suites Southwest St. Louis
3.0 star property
Valley Park
9.6 out of 10, Exceptional, (1,021 reviews)
"Place was clean, staff was very friendly loved the hot tub!"
United States
Sophia
The price is HK$1,003
HK$1,173 total
includes taxes & fees
6 Jul - 7 Jul
Drury Inn & Suites Southwest St. Louis

Best Western Plus Washington Hotel

Best Western Plus Washington Hotel
2.5 star property
Washington
9.2 out of 10, Wonderful, (696 reviews)
"Very clean and staff were friendly. Breakfast was good and will definitely stay here again. "
United States
Rod
The price is HK$1,011
HK$1,151 total
includes taxes & fees
21 Jun - 22 Jun
Best Western Plus Washington Hotel

Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
2.5 star property
St. Charles
8.4 out of 10, Very good, (1,012 reviews)
"We had a great stay"
United States
Alexa
The price is HK$886
HK$1,018 total
includes taxes & fees
21 Jun - 22 Jun
Comfort Suites St Charles - St Louis

Holiday Inn Express & Suites St Peters by IHG

Holiday Inn Express & Suites St Peters by IHG
2.5 star property
St. Peters
9.4 out of 10, Exceptional, (415 reviews)
"Great stay. Easy and quick check in."
United States
John
The price is HK$823
HK$993 total
includes taxes & fees
21 Jun - 22 Jun
Holiday Inn Express & Suites St Peters by IHG

Quality Inn Near Six Flags St. Louis

Quality Inn Near Six Flags St. Louis
2.5 star property
Pacific
8.4 out of 10, Very good, (386 reviews)
"Great last minute booking when we needed to get off the road after a long day."
United States
Brent
The price is HK$886
HK$1,014 total
includes taxes & fees
18 Jun - 19 Jun
Quality Inn Near Six Flags St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Defiance attractions

Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

A covered bridge at the Historic Daniel Boone Home Park in Defiance, Missouri

Top Defiance Hotel Reviews

More cheap stays in Defiance

Frequently asked questions

What's the best place to stay in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham, located 17.9 mi (28.8 km) from the heart of Defiance, is a top choice for your stay, based on our traveller data. Two other options for your visit to the area are Hollywood Casino & Hotel St. Louis and Ameristar Casino Resort and Spa. See all available top hotels, or vacation rentals in Defiance.
What are some of the best holiday rentals that Defiance has to offer?
🌟 Adorable Historic 🏠 in the ❤️ of St. Charles 🌟: This holiday home rental outside of Defiance offers a patio, a garden and air conditioning to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge and a stovetop. See all vacation rentals in Defiance.
If I need to cancel my hotel reservation in Defiance, will I receive a refund?
Yes! The majority of room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.
What are some accommodation options with pools in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham: Features an indoor pool, an outdoor pool and buffet. Ameristar Casino Resort and Spa and The Wildwood Hotel are two additional hotels with an on-site pool. View all hotels with pools in Defiance.
How is it staying in Defiance?
Visitors can enjoy all that Defiance has to offer, including the wineries and parks. A top sight in the area is Six Flags St. Louis. In Defiance, there are 19 hotels and other accommodation options to choose from. Find out more about Defiance.
What should I do while I'm visiting Defiance?
Natural beauty is on display at August A. Busch Memorial Conservation Area, Missouri River and Matson Hill Park Trailhead. Additionally, you'll find Six Flags St. Louis in the area. Take a look at what more there is to see and do in Expedia's Defiance guide.
What's the weather like in Defiance?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.

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