St. Louis Historic Main Street Hotels

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Check prices for these dates

Tonight
11 Mar - 12 Mar
Tomorrow
12 Mar - 13 Mar
This weekend
13 Mar - 15 Mar
Next weekend
20 Mar - 22 Mar

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Our top choices for Historic Main Street hotels

Exterior

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
St. Charles Historic District, 1 km from Historic Main Street
9.4 out of 10, Exceptional, (1,001 reviews)
"Wonderful place staff awesome "
United States
Chad
The price is HK$904
HK$1,039 total
includes taxes & fees
5 Apr - 6 Apr
Country Inn & Suites by Radisson, St. Charles Historic District
Lobby

Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles
3.0 star property
1.8 km from Historic Main Street
9.6 out of 10, Exceptional, (1,001 reviews)
"Great hotel "
United States
John Christopher
The price is HK$1,127
HK$1,306 total
includes taxes & fees
3 Apr - 4 Apr
Drury Plaza Hotel St. Louis St. Charles
Free daily buffet breakfast

Hampton Inn & Suites St. Charles Old Town Area

Hampton Inn & Suites St. Charles Old Town Area
2.5 star property
1.5 km from Historic Main Street
9.0 out of 10, Wonderful, (663 reviews)
"Pleasant staff and clean room"
United States
Michele
The price is HK$892
HK$1,073 total
includes taxes & fees
5 Apr - 6 Apr
Hampton Inn & Suites St. Charles Old Town Area
Lobby

Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles
3.5 star property
2.1 km from Historic Main Street
8.8 out of 10, Excellent, (1,000 reviews)
"A beautiful hotel. "
United States
Jon Michael
The price is HK$956
HK$1,099 total
includes taxes & fees
5 Apr - 6 Apr
Embassy Suites by Hilton St. Louis St. Charles
Exterior

Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
2.5 star property
1.5 km from Historic Main Street
8.4 out of 10, Very good, (1,009 reviews)
"Great hotel for the money"
United States
Jere
The price is HK$682
HK$783 total
includes taxes & fees
5 Apr - 6 Apr
Comfort Suites St Charles - St Louis
Seasonal outdoor pool

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
1.4 km from Historic Main Street
8.4 out of 10, Very good, (1,000 reviews)
"The room was great. I enjoyed my stay. "
United States
Wanda
The price is HK$1,401
HK$1,768 total
includes taxes & fees
17 Mar - 18 Mar
Ameristar Casino Resort and Spa
Exterior

Tru by Hilton St. Charles St. Louis, MO

Tru by Hilton St. Charles St. Louis, MO
2.5 star property
2.1 km from Historic Main Street
8.6 out of 10, Excellent, (801 reviews)
"Clean, great breakfast options."
United States
Kristy
The price is HK$892
HK$1,034 total
includes taxes & fees
29 Mar - 30 Mar
Tru by Hilton St. Charles St. Louis, MO
3 bars/lounges

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis
3.5 star property
3 km from Historic Main Street
8.4 out of 10, Very good, (2,219 reviews)
"Fun place to stay"
Canada
James
The price is HK$731
HK$967 total
includes taxes & fees
5 Apr - 6 Apr
Hollywood Casino & Hotel St. Louis
Terrace/patio

Holiday Inn St. Louis Arpt West-Earth City by IHG

Holiday Inn St. Louis Arpt West-Earth City by IHG
3.5 star property
2.9 km from Historic Main Street
7.6 out of 10, Good, (1,002 reviews)
"It’s near to the exit to the highway "
United States
Gabriel
The price is HK$673
HK$774 total
includes taxes & fees
5 Apr - 6 Apr
Holiday Inn St. Louis Arpt West-Earth City by IHG
Exterior

Elimwood Hotel, a Ramada by Wyndham

Elimwood Hotel, a Ramada by Wyndham
3.0 star property
3.1 km from Historic Main Street
7.4 out of 10, Good, (1,000 reviews)
"Nice rooms, pet friendly, small lake in the back with a sitting area, very relaxing stay"
United States
Michelle
The price is HK$725
HK$841 total
includes taxes & fees
29 Mar - 30 Mar
Elimwood Hotel, a Ramada by Wyndham
Interior entrance

Americas Best Value Inn & Suites St. Louis, St. Charles Inn

Americas Best Value Inn & Suites St. Louis, St. Charles Inn
2.5 star property
1.6 km from Historic Main Street
5.8 out of 10, (1,005 reviews)
"Great place"
United States
Christina
The price is HK$704
HK$816 total
includes taxes & fees
15 Mar - 16 Mar
Americas Best Value Inn & Suites St. Louis, St. Charles Inn
Fridge, microwave, stovetop, dishwasher

Sonesta Simply Suites St Louis Earth City

Sonesta Simply Suites St Louis Earth City
2.0 star property
3.3 km from Historic Main Street
8.6 out of 10, Excellent, (844 reviews)
"The rooms were spotless and the staff was great would definitley recommend "
United States
Trish
The price is HK$728
HK$837 total
includes taxes & fees
30 Mar - 31 Mar
Sonesta Simply Suites St Louis Earth City
Free daily buffet breakfast

SpringHill Suites by Marriott St. Louis Airport/Earth City

SpringHill Suites by Marriott St. Louis Airport/Earth City
3.0 star property
4.2 km from Historic Main Street
8.8 out of 10, Excellent, (1,000 reviews)
"It was overall a great stay. They were friendly, it was clean and quiet"
United States
Brent
The price is HK$939
HK$1,115 total
includes taxes & fees
22 Mar - 23 Mar
SpringHill Suites by Marriott St. Louis Airport/Earth City
Breakfast and dinner served, American cuisine

Courtyard St. Louis Airport/Earth City

Courtyard St. Louis Airport/Earth City
3.0 star property
4.2 km from Historic Main Street
8.4 out of 10, Very good, (1,003 reviews)
"Clean, quiet hotel with all the amenities you’d need. Located in a business park which I appreciated as a solo traveler staying overnight in St. Louis on a Saturday night. "
United States
Alissa
The price is HK$725
HK$866 total
includes taxes & fees
22 Mar - 23 Mar
Courtyard St. Louis Airport/Earth City
Lobby sitting area

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
3.0 star property
3.6 km from Historic Main Street
7.6 out of 10, Good, (1,002 reviews)
"Our stay was very nice. I love the room and the space! Food could be better, but overall it was a good stay for the price."
United States
Dominica
The price is HK$545
HK$633 total
includes taxes & fees
2 Apr - 3 Apr
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
Premium bedding, desk, iron/ironing board, free cots/infant beds

Super 8 by Wyndham St Charles

Super 8 by Wyndham St Charles
2.0 star property
4.7 km from Historic Main Street
8.0 out of 10, Very good, (1,008 reviews)
"Great place to stay for the $$$"
United States
Kale
The price is HK$625
HK$719 total
includes taxes & fees
17 Mar - 18 Mar
Super 8 by Wyndham St Charles
Exterior

Holiday Inn Express Hotel and Suites St. Charles by IHG

Holiday Inn Express Hotel and Suites St. Charles by IHG
3.0 star property
5 km from Historic Main Street
8.2 out of 10, Very good, (722 reviews)
"Good place to stay"
United States
Dustin
The price is HK$1,088
HK$1,250 total
includes taxes & fees
22 Mar - 23 Mar
Holiday Inn Express Hotel and Suites St. Charles by IHG
Lobby

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
10.6 km from Historic Main Street
9.4 out of 10, Exceptional, (2,856 reviews)
"Great stay"
United States
Brandy
The price is HK$704
HK$829 total
includes taxes & fees
22 Mar - 23 Mar
Pear Tree Inn St. Louis Airport
Lobby

Motel 6 Hazelwood, MO

Motel 6 Hazelwood, MO
2.0 star property
8.2 km from Historic Main Street
8.6 out of 10, Excellent, (1,832 reviews)
"Nice Stay!"
United States
Avalynn
The price is HK$468
HK$572 total
includes taxes & fees
25 Mar - 26 Mar
Motel 6 Hazelwood, MO
Exterior

Candlewood Suites St Louis St Charles by IHG

Candlewood Suites St Louis St Charles by IHG
2.5 star property
4 km from Historic Main Street
7.6 out of 10, Good, (786 reviews)
"The staff was very professional and the room was clean. I will definitely book here again"
United States
Ngozi
The price is HK$657
HK$755 total
includes taxes & fees
15 Mar - 16 Mar
Candlewood Suites St Louis St Charles by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Historic Main Street Hotel Reviews

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

10/10 Excellent
"Only complaint is that we’re in 2026 and the tvs don’t come with Netflix "
Gage 2-night trip
Posted 1 day ago
Hollywood Casino & Hotel St. Louis

Hotels near other Historic Main Street attractions

Lewis & Clark festival
Photo by HA
Open Photo by HA

Frontier Park

You can find out about the history of St. Charles with a stop at Frontier Park. Visit the shops and top-notch restaurants in this family-friendly area.
See properties
trestle on Katy Trail in Missouri over Auxvasse Creek near Mokane - 237 mile bike trail stretching across most of the state of Missouri converted from abandoned railroad

Katy Trail

4.6/5 (53 reviews)
You can take time to visit Katy Trail during your travels to St. Charles. Experience the acclaimed theatre scene and great live music in this family-friendly area.
See properties

Frequently asked questions

What's the area like around Historic Main Street?
Historic Main Street is located in St. Charles. This historic area is known for its array of dining options and major shopping area. If you're looking for a convenient place to stay, take a look at the 90 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to Historic Main Street?
Ameristar Casino Resort and Spa is one of the top choices for your stay based on our traveller data, and this hotel offers a full-service spa and a casino. It's located just a short 0.9 mi (1.4 km) from Historic Main Street. Other good options close by include Country Inn & Suites by Radisson, St. Charles Historic District and The Hare Suite at Divine Otter.
How many hotels are there near Historic Main Street?
Expedia has 90 hotels and other accommodation options within a mile from Historic Main Street.
If I need to cancel the hotel reservation for my stay near Historic Main Street, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If your reservation is non-refundable, you may still be able to cancel and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to get the best options available near Historic Main Street.
What can I see and do near Historic Main Street?
Sights like First Missouri State Capitol Historic Site and Lewis & Clark Boathouse and Nature Center highlight some of the local culture. Create some family memories at Centene Community Ice Center and Kokomo Joe's Family Fun Center. At Hollywood Casino Amphitheatre, Missouri Artists on Main and Historic Aircraft Restoration Museum, you'll experience some of the local culture.