Best Keowee Hotels in 2026 from HK$511 - Fully Refundable Options

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Our top choices for Keowee hotels

A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.

A spacious restaurant with high ceilings, wooden flooring, and a mix of modern and classic furniture.

A modern bar area with a wooden ceiling, green bar stools, and a bar counter.

An outdoor patio with wicker furniture, a round table, and a fountain.

1. The Shepherd Hotel Downtown Clemson

Clemson

Laurrie

HK$1,640

HK$1,821 total

includes taxes & fees

13 Oct - 14 Oct

An outdoor patio area with a fire pit, seating, and string lights.

A modern hotel with a prominent 'tru by Hilton' sign, a well-lit entrance, and a parking area.

A food court with a beverage display, seating area, and a Clemson University sign.

A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.

2. Tru by Hilton Seneca Clemson

Seneca

Gretchen

HK$830

HK$913 total

includes taxes & fees

11 Oct - 12 Oct

A golf course with a water body, trees, and a distant view of a bridge.

A modern building with a central entrance, surrounded by a well-maintained lawn and trees.

A golf course with a clubhouse, surrounded by dense trees and a large body of water.

An outdoor patio with tables and chairs, surrounded by trees and a view of a body of water.

3. Clemson University's James F. Martin Inn

Clemson

Lilllian

HK$1,169

HK$1,298 total

includes taxes & fees

6 Oct - 7 Oct

A Holiday Inn Express hotel with a stone facade, large windows, and a parking lot.

A conference room with a large round table, multiple chairs, and a projector.

A hotel breakfast area with a self-serve station, including a refrigerator, coffee machine, and fruit display.

A modern living room with a flat-screen TV, a desk with a chair, an orange sofa, and a framed tiger picture on the wall.

4. Holiday Inn Express & Suites Clemson by IHG

Clemson

John

HK$1,012

HK$1,124 total

includes taxes & fees

11 Oct - 12 Oct

A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.

An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.

A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.

A spacious lobby with a stone fireplace, modern lighting fixtures, and a seating area with sofas and a coffee table.

5. Lakeside Lodge Clemson

Seneca

Lori

HK$828

HK$1,030 total

includes taxes & fees

6 Oct - 7 Oct

A conference room with multiple tables and chairs, large windows with curtains, and abstract art on the walls.

A modern dining area with a bar, bar stools, and a patterned rug.

A Courtyard Marriott hotel with a brick facade, multiple floors, and a covered entrance area.

A modern lobby with a reception desk, a seating area with three chairs, a round table, and a bookshelf with books.

6. Courtyard Marriott Clemson

Clemson

kim

HK$982

HK$1,090 total

includes taxes & fees

18 Oct - 19 Oct

A modern kitchen area with a bar counter and seating.

A vending area with snacks and beverages, including chips and soda.

A modern living room with a grey sofa, purple and orange cushions, a coffee table with magazines, and a large window with patterned curtains.

A modern bar area with high stools and a poolside view.

7. Hampton Inn Clemson-University Area

Clemson

Blaise

HK$860

HK$955 total

includes taxes & fees

11 Oct - 12 Oct

A poolside area with outdoor seating and a view of a lake and forested hills.

A modern lobby with a reception desk, seating area, and a vending machine.

A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.

A modern cafe interior with round tables and chairs, a counter with a beverage dispenser, and a wall-mounted TV.

8. Fairfield Inn & Suites Seneca Clemson Univ Area

Seneca

Angela

HK$941

HK$1,036 total

includes taxes & fees

11 Oct - 12 Oct

A spacious indoor dining area with multiple tables and chairs, a food service counter, and a modern architectural design with balconies.

A spacious indoor area with multiple seating arrangements, a ping pong table, and a bar area with purple accents.

A lobby with seating areas, a reception desk, and a patterned wall.

A hotel room with a bed, a desk, a TV, a mirror, and a nightstand with a lamp.

9. Best Western Plus Clemson Hotel & Conference Center

Clemson

David

HK$827

HK$918 total

includes taxes & fees

8 Oct - 9 Oct

A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.

A multi-story hotel with a prominent entrance, a parking lot, and a landscaped area with a small tree.

A modern living room with a sofa, two armchairs, a coffee table, and a potted plant.

A bar area with a counter, multiple chairs, and a display of bottles and glasses.

10. The Abernathy of Clemson

Clemson

Robert

HK$1,264

HK$1,403 total

includes taxes & fees

18 Oct - 19 Oct

A spacious hallway with a wooden ceiling, a sofa, a chair, and a lamp.

A hotel lobby with a long corridor, seating areas, and a reception desk.

A brick building with a sign reading "The Inn at Patrick Square".

A hotel with a brick facade, multiple windows, and a sign reading "The Inn at Patrick Square".

11. The Inn at Patrick Square

Clemson

Jennifer

HK$1,169

HK$1,298 total

includes taxes & fees

6 Oct - 7 Oct

A reception area with a reception desk, a sofa, a staircase, and a wall with artwork.

A tiger mascot holding a sign with "HOWARD'S ROCK" text, a staircase, and a desk with a computer.

A hotel room with two beds, a desk, a television, and a clock on the wall.

A dining area with a brick floor, wooden tables, and chairs, a kitchen counter with appliances, and large windows offering a view of the outside.

12. Inn @ Clemson

Clemson

Heather

HK$629

HK$698 total

includes taxes & fees

6 Oct - 7 Oct

A modern kitchen with a microwave, toaster, and coffee maker. There are white bowls and a coffee station.

A hotel reception area with two reception desks, a digital screen, and a tiled floor.

A hotel hallway with a carpeted floor, light-colored walls, and doors on both sides.

13. Comfort Inn & Suites Clemson - University Area

Clemson

Yvette

HK$840

HK$933 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.

A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.

A reception area with a brick wall, a reception desk, and a glass door leading outside.

A multi-story hotel with a prominent entrance, parking area, and a car parked in front.

14. Best Western Seneca-Clemson

Seneca

Michelle

HK$734

HK$807 total

includes taxes & fees

28 Oct - 29 Oct

A dining area with a table and chairs, large windows with a view of the outside, and a green sofa.

A gazebo with a tiled roof and a surrounding gravel area.

A reception desk with a vase of flowers, framed pictures, and a printer.

A hotel room with two beds, a desk, a chair, a TV, and a painting on the wall.

15. Days Inn by Wyndham Clemson

Clemson

"While my room was very clean, there was a large stain on the upholstered chair by the window. The picture was missing the bottom part of the frame. The bathroom was old, with a cigarette stain on the tub. Staff were friendly and helpful but it took longer than usual to check in. There was no pepper in the breakfast area and the juice machine was broken. All said and done, I had what I needed. It is a poor economy for all which may explain the shortcomings."

Cynthia

HK$629

HK$698 total

includes taxes & fees

6 Oct - 7 Oct

A modern hotel room with a large bed, a desk with a chair, a small table, and a nightstand with a lamp.

A coffee station with two coffee machines, a coffee press, and various coffee pods and cups.

A breakfast station with a toaster, a fruit bowl, and a bakery display.

A Holiday Inn Express & Suites hotel with a modern architectural design, featuring a prominent entrance with columns and a flat roof.

16. Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Anderson

Dominique

HK$863

HK$958 total

includes taxes & fees

11 Oct - 12 Oct

A hotel dining area with a long table, multiple chairs, and a bar in the background.

A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.

A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.

A reception area with a counter, chairs, and a patterned rug.

17. Hampton Inn & Suites Seneca-Clemson Area

Seneca

Lloyd

HK$931

HK$1,024 total

includes taxes & fees

11 Oct - 12 Oct

A poolside area with wicker furniture and a table, surrounded by a fence and greenery.

A corner market with a wooden interior, a glass door entrance, and a refrigerator display.

A Fairfield by Marriott hotel with a modern design, featuring a covered entrance, multiple floors, and a well-lit facade.

A modern living room with a stone wall, a fireplace, and a large window. There are two sofas, a coffee table, and a dining area with a table and chairs.

18. Fairfield Inn & Suites by Marriott Anderson Clemson

Anderson

James

HK$770

HK$855 total

includes taxes & fees

11 Oct - 12 Oct

A white, two-story house with a front porch, surrounded by trees and shrubs.

A dining area with round tables, black chairs, and white tablecloths.

A bedroom with two beds, a TV, and a fireplace.

A two-story building with a white exterior, a front door, and a balcony.

19. Liberty Hall Bed and Breakfast

Pendleton

Christine

HK$895

HK$994 total

includes taxes & fees

8 Oct - 9 Oct

A modern bar area with a marble counter, houndstooth patterned chairs, and pendant lighting.

A patio area with stone walls, outdoor furniture, and large windows.

A modern interior with round tables, houndstooth patterned chairs, a bar area, and a view through large windows.

A spacious living area with a sofa, two armchairs, a coffee table, and a chandelier. Large windows provide a view of the outdoors.

20. Holiday Inn Anderson by IHG

Anderson

Deirdre

HK$926

HK$1,028 total

includes taxes & fees

2 Nov - 3 Nov

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Top Keowee Hotel Reviews

Days Inn by Wyndham Anderson

8/10 Good

"-"

The Abernathy of Clemson

10/10 Excellent

"You can’t beat the location and rooms are fabulous!"

Comfort Suites Anderson-Clemson

8/10 Good

"OK for night or two if you are catching a game in Clemson. Movie theater right across the road and couple of restaurants within close walking distance."

Comfort Inn & Suites Clemson - University Area

10/10 Excellent

"Very clean room with a great staff! Breakfast was excellent!"

Woodspring Suites Anderson North I-85

8/10 Good

"Everything was great only thing I would make note of is the shower curtain had mold on it."

Horizon Inn & Suites

10/10 Excellent

"The pretty lady at the front desk is absolutely fabulous."

The Shepherd Hotel Downtown Clemson

10/10 Excellent

"It was a lovely from beginning to end. The staff is amazing."

Inn @ Clemson

10/10 Excellent

"Clean room close to Clemson"

Hampton Inn & Suites Seneca-Clemson Area

10/10 Excellent

"Great place to stay when visiting Clemson!"

More cheap stays in Keowee

Days Inn by Wyndham Anderson

1007 George Smith Mill Rd Anderson SC

HK$460

HK$511 total

11 Oct - 12 Oct

includes taxes & fees

8.2/10 Very good! (1,007 reviews)

Horizon Inn & Suites

3025 N Main Street Anderson SC

HK$439

HK$519 total

8 Oct - 9 Oct

includes taxes & fees

4.6/10 (365 reviews)

Quality Inn Seneca US-123

226 Hi Tech Rd Seneca SC

HK$593

HK$700 total

11 Oct - 12 Oct

includes taxes & fees

8/10 Very good! (755 reviews)

Best Western Plus Clemson Hotel & Conference Center

1310 Tiger Blvd Clemson SC

HK$827

HK$918 total

8 Oct - 9 Oct

includes taxes & fees

Comfort Inn & Suites Clemson - University Area

1305 Tiger Blvd Clemson SC

HK$840

HK$933 total

18 Oct - 19 Oct

includes taxes & fees

8.4/10 Very good! (1,007 reviews)

Lakeside Lodge Clemson

13500 Clemson Blvd Seneca SC

HK$828

HK$1,030 total

6 Oct - 7 Oct

includes taxes & fees

Frequently asked questions

What's the best place to stay in Keowee?

Located 3.1 mi (4.9 km) from the heart of Keowee, Best Western Plus Clemson Hotel & Conference Center is a top choice for your stay, based on our traveller data. Two other options for your trip to the area are Lakeside Lodge Clemson and Days Inn by Wyndham Anderson. See all available top hotels, or vacation rentals in Keowee.

What are some of the best holiday rentals that Keowee has to offer?

Lake Jocassee ~ Easy Lake Access ~ Loved By Our Guests ~ Pet Friendly: This holiday home rental outside of Keowee is located on a lake, and has a fireplace, a balcony and a BBQ to put you at ease in your new surroundings. It has 4 bedrooms, as well as a kitchen with a fridge, a stovetop and a microwave, so that you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games. See all vacation rentals in Keowee.

If I need to cancel my hotel reservation in Keowee, will I receive a refund?

Yes, you'll find most hotel bookings are refundable if you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Keowee.

What is the top LGBTQ-friendly hotel in Keowee?

Tru by Hilton Seneca Clemson is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. See all available hotels listed as LGBTQ-friendly in Keowee.

What's the best dog-friendly hotel in Keowee?

Tru by Hilton Seneca Clemson is a top hotel for people travelling with their pets, and offers a fitness centre and laundry facilities for its human guests. See more pet-friendly hotel accommodations in Keowee.

What are some accommodation options with pools in Keowee?

Days Inn by Wyndham Anderson: Offers daily, a seasonal outdoor pool and free self parking. Best Western Plus Clemson Hotel & Conference Center and Quality Inn Seneca Clemson Area US-123 are a couple of other choices with an on-site pool. View all hotels with pools in Keowee.

How is it staying in Keowee?

Travellers to Keowee will find plenty to explore and enjoy. There are 1382 hotels and other accommodation options in the surrounding area. Find out more about Keowee.

What should I do while I'm visiting Keowee?

Places to visit in the wider area include Littlejohn Coliseum, Memorial Stadium and Fort Hill. You'll also find Walker Golf Course and Brooks Center for the Performing Arts in the area. Take a look at what more there is to see and do in Expedia's Keowee guide.

What's the seasonal weather in Keowee?

The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 8°C. Average annual precipitation for Keowee is 1561 mm.

Keowee hotels from HK$511

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Keowee

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Keowee hotels

1. The Shepherd Hotel Downtown Clemson

2. Tru by Hilton Seneca Clemson

3. Clemson University's James F. Martin Inn

4. Holiday Inn Express & Suites Clemson by IHG

5. Lakeside Lodge Clemson

6. Courtyard Marriott Clemson

7. Hampton Inn Clemson-University Area

8. Fairfield Inn & Suites Seneca Clemson Univ Area

9. Best Western Plus Clemson Hotel & Conference Center

10. The Abernathy of Clemson

11. The Inn at Patrick Square

12. Inn @ Clemson

13. Comfort Inn & Suites Clemson - University Area

14. Best Western Seneca-Clemson

15. Days Inn by Wyndham Clemson

16. Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

17. Hampton Inn & Suites Seneca-Clemson Area

18. Fairfield Inn & Suites by Marriott Anderson Clemson

19. Liberty Hall Bed and Breakfast

20. Holiday Inn Anderson by IHG

Top Keowee Hotel Reviews

Days Inn by Wyndham Anderson

The Abernathy of Clemson

Comfort Suites Anderson-Clemson

Comfort Inn & Suites Clemson - University Area

Woodspring Suites Anderson North I-85

Horizon Inn & Suites

The Shepherd Hotel Downtown Clemson

Inn @ Clemson

Hampton Inn & Suites Seneca-Clemson Area

More cheap stays in Keowee

Days Inn by Wyndham Anderson

Horizon Inn & Suites

Quality Inn Seneca US-123

Best Western Plus Clemson Hotel & Conference Center

Comfort Inn & Suites Clemson - University Area

Lakeside Lodge Clemson

Frequently asked questions

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