Best McClure Hotels in 2026 from HK$527 - Fully Refundable Options

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Our top choices for McClure hotels

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

A hotel room with a bed, desk, chair, TV, and a small kitchenette area.

A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.

A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.

1. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Cape Girardeau

Rebecca

HK$746

HK$849 total

includes taxes & fees

15 Nov - 16 Nov

A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.

A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.

A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.

A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.

2. Drury Inn & Suites Cape Girardeau

Cape Girardeau

DENNIS

HK$706

HK$797 total

includes taxes & fees

25 Oct - 26 Oct

A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.

An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.

A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.

3. Fairfield Inn & Suites by Marriott Cape Girardeau

Cape Girardeau

Carlos

HK$794

HK$896 total

includes taxes & fees

25 Oct - 26 Oct

A spacious dining area with high ceilings, large windows, and modern lighting fixtures.

A large indoor swimming pool with clear blue water, surrounded by tiled flooring and blue walls.

An outdoor patio with stone walls, wicker furniture, and large windows.

A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.

4. Hampton Inn Cape Girardeau I 55 East

Cape Girardeau

Rebekah

HK$830

HK$937 total

includes taxes & fees

25 Oct - 26 Oct

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.

A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.

5. Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

Darnetta

HK$785

HK$885 total

includes taxes & fees

22 Oct - 23 Oct

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.

A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.

A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.

6. Pear Tree Inn Cape Girardeau West

Cape Girardeau

Troy

HK$565

HK$637 total

includes taxes & fees

25 Oct - 26 Oct

A spacious lobby with marble flooring, elegant seating, and a grand staircase.

A lobby with seating areas, a reception desk, and a bar.

A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.

A modern hotel lobby with a framed advertisement for breakfast at the new Bistro, a seating area with sofas and a coffee table, and a decorative mirror reflecting the space.

7. Courtyard by Marriott Cape Girardeau Downtown

Cape Girardeau

Kristin

HK$982

HK$1,113 total

includes taxes & fees

29 Oct - 30 Oct

A modern bathroom with a marble vanity, a round mirror, a glass shower enclosure, and a towel rack.

A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.

A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

A hotel room with two beds, a desk, a chair, and a view of the city.

8. The Riverview

Cape Girardeau

Scotty

HK$897

HK$1,012 total

includes taxes & fees

19 Oct - 20 Oct

A modern retail area with a display of local items and snacks.

An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.

A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.

A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

9. Tru By Hilton Cape Girardeau

Cape Girardeau

Shannon

HK$701

HK$798 total

includes taxes & fees

25 Oct - 26 Oct

A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

A hotel room with two beds, a nightstand, a lamp, and a chair.

A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.

A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.

10. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

Elaine

HK$627

HK$679 total

includes taxes & fees

1 Nov - 2 Nov

A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.

A hotel patio with a gazebo, outdoor seating, and a view of the road.

An indoor swimming pool with tiled flooring, a seating area with chairs, and a staircase leading to a door.

A hotel room with a bed, a TV, a desk, and a chair.

11. Candlewood Suites Cape Girardeau by IHG

Cape Girardeau

Samuel

HK$565

HK$681 total

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with large windows, comfortable seating, and a modern ceiling design.

A hotel room with a bed, a dark sofa, an ottoman, a lamp, and artwork on the wall.

A room with large windows, two red upholstered chairs, a small table, and a potted plant.

A breakfast bar with coffee machines, a cereal dispenser, and a fruit display.

12. Comfort Suites Jackson-Cape Girardeau

Jackson

VICTORIA

HK$594

HK$643 total

includes taxes & fees

8 Nov - 9 Nov

A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.

A restaurant with multiple tables and chairs, an exit sign, a television, and a counter with food items.

A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'

A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.

13. Quality Inn Cape Girardeau North

Cape Girardeau

Dayanita

HK$467

HK$527 total

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

A restaurant with a brick wall, a flat-screen TV, and a bar area.

A hotel room with two beds, a brick wall, and a wooden headboard.

An indoor swimming pool with a wooden ceiling, lounge chairs, and a lifeguard chair.

14. Drury Inn & Suites Jackson MO

Jackson

Lyn

HK$628

HK$664 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.

A hotel room with a kitchenette, a bed, a dining table with chairs, a TV mounted on the wall, and a dresser.

A motel with multiple floors, a parking lot, and a staircase leading to the upper floors.

A bathroom with a marble wall and a white bathtub.

15. Town House Inn Cape Giradreau

Cape Girardeau

Hope

HK$549

HK$642 total

includes taxes & fees

19 Oct - 20 Oct

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Top McClure Hotel Reviews

Tru By Hilton Cape Girardeau

10/10 Excellent

"A new property that is very clean and well trained staff"

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

10/10 Excellent

"We have stayed here frequently. Great place to stay."

Courtyard by Marriott Cape Girardeau Downtown

10/10 Excellent

"I was surprised how reasonable the cost was considering how clean & nice all of the finishers were."

Drury Inn & Suites Jackson MO

10/10 Excellent

"Lovely hotel. Extremely happy with the accommodations. The hotel and room was very clean. The complimentary dinner was delicious. The pool area and workout room were clean and pleasant. Cute courtyard. Very happy with the service!"

Hampton Inn Cape Girardeau I 55 East

8/10 Good

"It was good. No complaints. The walls weren't terrible. No smells. It was clean & nice."

Pear Tree Inn Cape Girardeau West

10/10 Excellent

"We have stayed at the Pear Tree several times and never disappointed!! Great staff, clean rooms, generous breakfast. A special thanks to Lydia who took extra care to make our last stay remarkable. Thank you."

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

10/10 Excellent

"We have stayed here a number of times over 20 years. It’s always clean and well maintained. Breakfast is very good. Staff is always friendly and helpful."

Amazing Lakeside hot tub, A-frame 3 King Beds, Shawnee Forest sleeps 2-6 Firepit

10/10 Excellent

"Loved staying here for my bachelorette trip, will definitely be back!"

* On the Wine Trail * Hot Tub * Wi-Fi *

10/10 Excellent

"Had a great time!!! It was nice to relax in the hot tub each night after full days on the wine trail. Great host!!!"

More cheap stays in McClure

Quality Inn Cape Girardeau North

2011 North Kingshighway Cape Girardeau MO

HK$467

HK$527 total

1 Nov - 2 Nov

includes taxes & fees

Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy Cape Girardeau MO

HK$565

HK$637 total

25 Oct - 26 Oct

includes taxes & fees

9.2/10 Wonderful! (1,004 reviews)

Candlewood Suites Cape Girardeau by IHG

485 S Mount Auburn Rd Cape Girardeau MO

HK$565

HK$681 total

1 Nov - 2 Nov

includes taxes & fees

Tru By Hilton Cape Girardeau

2520 Veterans Memorial Dr Cape Girardeau MO

HK$701

HK$798 total

25 Oct - 26 Oct

includes taxes & fees

9.6/10 Exceptional! (195 reviews)

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

3253 William Street Cape Girardeau MO

HK$746

HK$849 total

15 Nov - 16 Nov

includes taxes & fees

Hotel 7 Inn Anna

100 Richview Dr Anna IL

Get rates

Frequently asked questions

What's the best place for a stay in McClure?

Located 8.2 mi (13.2 km) from the heart of McClure, Drury Plaza Hotel Cape Girardeau Conference Center is a top choice for your stay, based on our traveller data. Two other options for your visit to the area are Pear Tree Inn Cape Girardeau West and The Riverview. See all available top hotels, or vacation rentals in McClure.

What are some of the best holiday rentals that McClure has to offer?

On the Wine Trail Hot Tub Wi-Fi : This holiday home rental outside of McClure is located on a lake, and has a patio, 1 hot tub and a BBQ to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop and a microwave. See all vacation rentals in McClure.

If I need to cancel my hotel reservation in McClure, will I receive a refund?

Yes, you'll find most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in McClure.

What is staying in McClure like?

Those travelling to McClure will definitely enjoy the sights to see and things to do. There are 147 hotels and other accommodation options in the surrounding area. Find out more about McClure.

What is there to see in McClure?

A favourite place to visit is Devil's Island Wildlife Management Area. You'll also find Century Casino & Hotel Cape Girardeau and Hunter Valley Winery in the area. Take a look at what more there is to see and do in Expedia's McClure guide.

What's the seasonal weather like in McClure?

The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for McClure is 1491 mm.

McClure hotels from HK$527

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in McClure

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for McClure hotels

1. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2. Drury Inn & Suites Cape Girardeau

3. Fairfield Inn & Suites by Marriott Cape Girardeau

4. Hampton Inn Cape Girardeau I 55 East

5. Drury Plaza Hotel Cape Girardeau Conference Center

6. Pear Tree Inn Cape Girardeau West

7. Courtyard by Marriott Cape Girardeau Downtown

8. The Riverview

9. Tru By Hilton Cape Girardeau

10. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

11. Candlewood Suites Cape Girardeau by IHG

12. Comfort Suites Jackson-Cape Girardeau

13. Quality Inn Cape Girardeau North

14. Drury Inn & Suites Jackson MO

15. Town House Inn Cape Giradreau

Top McClure Hotel Reviews

Tru By Hilton Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Courtyard by Marriott Cape Girardeau Downtown

Drury Inn & Suites Jackson MO

Hampton Inn Cape Girardeau I 55 East

Pear Tree Inn Cape Girardeau West

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Amazing Lakeside hot tub, A-frame 3 King Beds, Shawnee Forest sleeps 2-6 Firepit

* On the Wine Trail * Hot Tub * Wi-Fi *

More cheap stays in McClure

Quality Inn Cape Girardeau North

Pear Tree Inn Cape Girardeau West

Candlewood Suites Cape Girardeau by IHG

Tru By Hilton Cape Girardeau

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Hotel 7 Inn Anna

Frequently asked questions

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