Otay Mesa hotels in San Diego

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Our top choices for Otay Mesa hotels

Quality Suites San Diego Otay Mesa

Quality Suites San Diego Otay Mesa
2.5 star property
Otay Mesa
7.0 out of 10, Good, (1,000 reviews)
"Great staff.. location close to the airport!"
United States
Vivian
The price is HK$772
HK$878 total
includes taxes & fees
4 Feb - 5 Feb
Quality Suites San Diego Otay Mesa

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2.5 star property
Otay Mesa
8.0 out of 10, Very good, (1,613 reviews)
"rooms clean and service great"
United States
patricia
The price is HK$1,045
HK$1,189 total
includes taxes & fees
1 Feb - 2 Feb
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Courtyard by Marriott Old Town

Courtyard by Marriott Old Town
3.0 star property
Old Town San Diego, 29.7 km from Otay Mesa
8.6 out of 10, Excellent, (1,002 reviews)
"Wonderful location and staff is outstanding!!"
United States
Kathleen
The price is HK$1,055
HK$1,212 total
includes taxes & fees
8 Feb - 9 Feb
Courtyard by Marriott Old Town

Berkshire Motor Hotel

Berkshire Motor Hotel
2.5 star property
North Park, 26.7 km from Otay Mesa
8.4 out of 10, Very good, (1,001 reviews)
"Clean, very chill easy check in"
United States
Susana
The price is HK$666
HK$751 total
includes taxes & fees
1 Feb - 2 Feb
Berkshire Motor Hotel

Westgate Hotel

Westgate Hotel
4.5 star property
24.9 km from Otay Mesa
9.0 out of 10, Wonderful, (1,003 reviews)
"Great stay"
United States
ESMERALDA
Westgate Hotel

Ocean Villa Inn

Ocean Villa Inn
2.5 star property
Ocean Beach, 33.7 km from Otay Mesa
8.0 out of 10, Very good, (1,149 reviews)
"Beds are super comfy clean and renovated"
United States
Esmeralda
Ocean Villa Inn

Sea Harbor Hotel

Sea Harbor Hotel
2.0 star property
30.1 km from Otay Mesa
8.6 out of 10, Excellent, (1,000 reviews)
"Super clean rooms and a great location "
United States
Mark
Sea Harbor Hotel

Super 8 by Wyndham San Diego Hotel Circle

Super 8 by Wyndham San Diego Hotel Circle
2.0 star property
28.8 km from Otay Mesa
7.2 out of 10, Good, (669 reviews)
"Staff was great, the room was very clean."
Canada
Jennifer
The price is HK$564
HK$648 total
includes taxes & fees
4 Feb - 5 Feb
Super 8 by Wyndham San Diego Hotel Circle

Springhill Suites San Diego Mission Valley

Springhill Suites San Diego Mission Valley
3.5 star property
28.2 km from Otay Mesa
9.2 out of 10, Wonderful, (1,001 reviews)
"Very friendly staff, quick check-in, spacious room, and very clean! Great place to stay! "
United States
Jodi
The price is HK$1,318
HK$1,516 total
includes taxes & fees
1 Mar - 2 Mar
Springhill Suites San Diego Mission Valley

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Gaslamp Quarter, 24.2 km from Otay Mesa
9.4 out of 10, Exceptional, (1,002 reviews)
"Great location and stay. "
United States
Simran
The price is HK$673
HK$1,006 total
includes taxes & fees
26 Feb - 27 Feb
Staypineapple, Hotel Z, Gaslamp San Diego

Fairfield Inn & Suites San Diego Old Town

Fairfield Inn & Suites San Diego Old Town
2.5 star property
Old Town San Diego, 29.4 km from Otay Mesa
8.8 out of 10, Excellent, (1,009 reviews)
"Great location, clean rooms, good breakfast"
United States
Jingyi
The price is HK$1,117
HK$1,284 total
includes taxes & fees
23 Feb - 24 Feb
Fairfield Inn & Suites San Diego Old Town

Old Town Western Inn & Suites

Old Town Western Inn & Suites
2.5 star property
Old Town San Diego, 29.6 km from Otay Mesa
7.6 out of 10, Good, (1,005 reviews)
"Clean, good staff, quiet, good location "
United States
Raul
Old Town Western Inn & Suites

La Pensione Hotel

La Pensione Hotel
3.0 star property
Little Italy, 25.8 km from Otay Mesa
8.6 out of 10, Excellent, (1,910 reviews)
"Clean room, helpful and friendly staff, great location to walk to restaurants. "
United States
Annette
La Pensione Hotel

Heritage Inn San Diego

Heritage Inn San Diego
2.0 star property
31.8 km from Otay Mesa
7.4 out of 10, Good, (1,222 reviews)
"It was clean an pretty close from airport"
United States
Hortencia
The price is HK$492
HK$566 total
includes taxes & fees
4 Feb - 5 Feb
Heritage Inn San Diego

Ash&9th

Ash&9th
2.0 star property
24.7 km from Otay Mesa
8.4 out of 10, Very good, (297 reviews)
"Will stay again! "
United States
Darlene
The price is HK$681
HK$775 total
includes taxes & fees
1 Mar - 2 Mar
Ash&9th

Best Western Plus Bayside Inn

Best Western Plus Bayside Inn
3.0 star property
25.4 km from Otay Mesa
9.0 out of 10, Wonderful, (1,001 reviews)
"Excellent stay!"
United States
D'ette
The price is HK$1,134
HK$1,313 total
includes taxes & fees
22 Feb - 23 Feb
Best Western Plus Bayside Inn

Porto Vista Hotel Downtown

Porto Vista Hotel Downtown
3.5 star property
Little Italy, 25.8 km from Otay Mesa
6.8 out of 10, (1,214 reviews)
"Great stay, clean rooms and centrally located"
United States
Samuel
Porto Vista Hotel Downtown

The Inn at Sunset Cliffs

The Inn at Sunset Cliffs
2.5 star property
Ocean Beach, 32.9 km from Otay Mesa
9.2 out of 10, Wonderful, (1,000 reviews)
"Great location, staff was so friendly and courteous, and amazing views!"
United States
Katrina
The price is HK$1,682
HK$1,897 total
includes taxes & fees
12 Feb - 13 Feb
The Inn at Sunset Cliffs

Ocean Beach Hotel

Ocean Beach Hotel
3.0 star property
Ocean Beach, 33.5 km from Otay Mesa
8.8 out of 10, Excellent, (1,282 reviews)
"The hotel was a great environment and felt very safe and comfortable. "
United States
Charity
Ocean Beach Hotel

Comfort Inn San Diego Airport At The Harbor

Comfort Inn San Diego Airport At The Harbor
3.5 star property
30.1 km from Otay Mesa
7.8 out of 10, Good, (1,276 reviews)
"Great room, clean property and courteous staff"
United States
Reginald D.
The price is HK$704
HK$795 total
includes taxes & fees
16 Feb - 17 Feb
Comfort Inn San Diego Airport At The Harbor
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Otay Mesa

Find the best Otay Mesa areas for the activities you enjoy most. Learn more about Otay Mesa
Learn more about Otay Mesa

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Gaslamp Quarter

San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Dog Beach and Ocean Beach Farmers Market.

Top Otay Mesa Hotel Reviews

Frequently asked questions

What's it like in Otay Mesa?
Otay Mesa is a neighbourhood that travellers like for its beaches, restaurants and shopping.
Where is the best hotel for a stay in Otay Mesa?
Based on Expedia customer reviews, Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is the highest ranked property in Otay Mesa. This hotel offers free breakfast and an outdoor pool. Another top choice in the area is Quality Suites San Diego Otay Mesa.
If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?
Yes! Most room reservations are refundable provided that you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Add dates, click "Search", then filter by "fully refundable" to view top deals in Otay Mesa.
What is there to do in this San Diego neighbourhood?
A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.

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