Otay Mesa hotels in San Diego
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Our top choices for Otay Mesa hotels
Quality Suites San Diego Otay Mesa
Quality Suites San Diego Otay MesaOtay Mesa
7.0 out of 10, Good, (1,000 reviews)
"Great staff.. location close to the airport!"
Vivian
The price is HK$772
HK$878 total
includes taxes & fees
4 Feb - 5 Feb
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHGOtay Mesa
8.0 out of 10, Very good, (1,613 reviews)
"rooms clean and service great"
patricia
The price is HK$1,045
HK$1,189 total
includes taxes & fees
1 Feb - 2 Feb
Courtyard by Marriott Old Town
Courtyard by Marriott Old TownOld Town San Diego, 29.7 km from Otay Mesa
8.6 out of 10, Excellent, (1,002 reviews)
"Wonderful location and staff is outstanding!!"
Kathleen
The price is HK$1,055
HK$1,212 total
includes taxes & fees
8 Feb - 9 Feb
Berkshire Motor Hotel
Berkshire Motor HotelNorth Park, 26.7 km from Otay Mesa
8.4 out of 10, Very good, (1,001 reviews)
"Clean, very chill easy check in"
Susana
The price is HK$666
HK$751 total
includes taxes & fees
1 Feb - 2 Feb
Westgate Hotel
Westgate Hotel24.9 km from Otay Mesa
9.0 out of 10, Wonderful, (1,003 reviews)
"Great stay"
ESMERALDA
Ocean Villa Inn
Ocean Villa InnOcean Beach, 33.7 km from Otay Mesa
8.0 out of 10, Very good, (1,149 reviews)
"Beds are super comfy clean and renovated"
Esmeralda
Sea Harbor Hotel
Sea Harbor Hotel30.1 km from Otay Mesa
8.6 out of 10, Excellent, (1,000 reviews)
"Super clean rooms and a great location "
Mark
Super 8 by Wyndham San Diego Hotel Circle
Super 8 by Wyndham San Diego Hotel Circle28.8 km from Otay Mesa
7.2 out of 10, Good, (669 reviews)
"Staff was great, the room was very clean."
Jennifer
The price is HK$564
HK$648 total
includes taxes & fees
4 Feb - 5 Feb
Springhill Suites San Diego Mission Valley
Springhill Suites San Diego Mission Valley28.2 km from Otay Mesa
9.2 out of 10, Wonderful, (1,001 reviews)
"Very friendly staff, quick check-in, spacious room, and very clean! Great place to stay! "
Jodi
The price is HK$1,318
HK$1,516 total
includes taxes & fees
1 Mar - 2 Mar
Staypineapple, Hotel Z, Gaslamp San Diego
Staypineapple, Hotel Z, Gaslamp San DiegoGaslamp Quarter, 24.2 km from Otay Mesa
9.4 out of 10, Exceptional, (1,002 reviews)
"Great location and stay. "
Simran
The price is HK$673
HK$1,006 total
includes taxes & fees
26 Feb - 27 Feb
Fairfield Inn & Suites San Diego Old Town
Fairfield Inn & Suites San Diego Old TownOld Town San Diego, 29.4 km from Otay Mesa
8.8 out of 10, Excellent, (1,009 reviews)
"Great location, clean rooms, good breakfast"
Jingyi
The price is HK$1,117
HK$1,284 total
includes taxes & fees
23 Feb - 24 Feb
Old Town Western Inn & Suites
Old Town Western Inn & SuitesOld Town San Diego, 29.6 km from Otay Mesa
7.6 out of 10, Good, (1,005 reviews)
"Clean, good staff, quiet, good location "
Raul
La Pensione Hotel
La Pensione HotelLittle Italy, 25.8 km from Otay Mesa
8.6 out of 10, Excellent, (1,910 reviews)
"Clean room, helpful and friendly staff, great location to walk to restaurants. "
Annette
Heritage Inn San Diego
Heritage Inn San Diego31.8 km from Otay Mesa
7.4 out of 10, Good, (1,222 reviews)
"It was clean an pretty close from airport"
Hortencia
The price is HK$492
HK$566 total
includes taxes & fees
4 Feb - 5 Feb
Best Western Plus Bayside Inn
Best Western Plus Bayside Inn25.4 km from Otay Mesa
9.0 out of 10, Wonderful, (1,001 reviews)
"Excellent stay!"
D'ette
The price is HK$1,134
HK$1,313 total
includes taxes & fees
22 Feb - 23 Feb
Porto Vista Hotel Downtown
Porto Vista Hotel DowntownLittle Italy, 25.8 km from Otay Mesa
6.8 out of 10, (1,214 reviews)
"Great stay, clean rooms and centrally located"
Samuel
The Inn at Sunset Cliffs
The Inn at Sunset CliffsOcean Beach, 32.9 km from Otay Mesa
9.2 out of 10, Wonderful, (1,000 reviews)
"Great location, staff was so friendly and courteous, and amazing views!"
Katrina
The price is HK$1,682
HK$1,897 total
includes taxes & fees
12 Feb - 13 Feb
Ocean Beach Hotel
Ocean Beach HotelOcean Beach, 33.5 km from Otay Mesa
8.8 out of 10, Excellent, (1,282 reviews)
"The hotel was a great environment and felt very safe and comfortable. "
Charity
Comfort Inn San Diego Airport At The Harbor
Comfort Inn San Diego Airport At The Harbor30.1 km from Otay Mesa
7.8 out of 10, Good, (1,276 reviews)
"Great room, clean property and courteous staff"
Reginald D.
The price is HK$704
HK$795 total
includes taxes & fees
16 Feb - 17 Feb
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Otay Mesa
Find the best Otay Mesa areas for the activities you enjoy most. Learn more about Otay Mesa
Learn more about Otay Mesa
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Mission Beach
If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.
Pacific Beach
Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.
Gaslamp Quarter
San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.
Ocean Beach
Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Dog Beach and Ocean Beach Farmers Market.
Top Otay Mesa Hotel Reviews
Hampton Inn & Suites by Hilton San Diego SeaWorld
10/10 Excellent
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