Byron Oxbow Nature Center Hotels: 2026 Limited-Time Hotel Deals @Expedia

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Oxbow Nature Center hotels

A modern dining area with high tables, chairs, and pendant lighting.

A multi-story hotel with a modern design, featuring a prominent entrance with a covered area and a parking lot in front.

A reception desk with a large digital screen displaying a cityscape and the word "happy."

A hotel room with two beds, a desk with a computer, a chair, and a window with a view.

1. Hampton Inn & Suites Rochester-North

11.4 km from Oxbow Nature Center

Albert

HK$803

HK$925 total

includes taxes & fees

27 Sept - 28 Sept

A room with a fireplace, two leather armchairs, a sofa, and a large window providing a view of the outdoors.

A long, narrow hotel corridor with a carpeted floor, light fixtures along the walls, and a ceiling with recessed lighting.

A paved garden area with two benches, a potted plant with yellow flowers, and a variety of greenery.

A hotel room with a bed, a sink, a microwave, and a window with curtains.

2. Brentwood Inn & Suites

16 km from Oxbow Nature Center

Bryan

HK$980

HK$1,128 total

includes taxes & fees

3 Sept - 4 Sept

A spacious living area with a modern staircase, leather sofas, and contemporary lighting.

A modern interior with a large dining table, sofas, and a kitchen area.

An outdoor seating area with blue sofas and wicker chairs, a wooden table, and green ottomans on a tiled patio.

A rooftop pool area with lounge chairs and umbrellas, surrounded by a modern building with a brick facade.

3. The Berkman

15 km from Oxbow Nature Center

William

HK$1,158

HK$1,346 total

includes taxes & fees

3 Sept - 4 Sept

A self-service breakfast station with a waffle maker, coffee machines, and a variety of condiments.

A hotel room with a large bed, a desk, a chair, a television, and a window with curtains.

A hotel lobby with leather sofas, a stone fireplace, and a patterned carpet.

A reception area with a wooden reception desk, a red doormat, and framed awards on the wall.

4. Econo Lodge Mayo Clinic Area

18 km from Oxbow Nature Center

Markus

HK$555

HK$639 total

includes taxes & fees

27 Sept - 28 Sept

A spacious lobby with a reception desk, sofas, and a coffee table.

A lobby with a brown sofa, yellow armchairs, a coffee table, and a clock on the wall.

An indoor swimming pool with clear blue water, surrounded by tiled flooring and equipped with a pool ladder.

A Sleep Inn hotel with a covered entrance, stone pillars, and a clear blue sky.

5. Sleep Inn & Suites West-Near Medical Center

11.3 km from Oxbow Nature Center

Kaitlin

HK$673

HK$774 total

includes taxes & fees

27 Sept - 28 Sept

An outdoor patio area with a concrete floor, wooden fence, and string lights.

A modern living room with a stone fireplace, a blue armchair, a round coffee table, and a large window offering a view of the outdoors.

A Fairfield Inn & Suites hotel with a modern design, featuring a prominent entrance and a parking area.

6. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

14.4 km from Oxbow Nature Center

Jon

HK$875

HK$1,007 total

includes taxes & fees

18 Sept - 19 Sept

An outdoor patio area with yellow umbrellas, wicker furniture, and a sign for Centerstone Plaza Hotel.

A modern reception area with a wooden reception desk, glass pendant lights, and a long hallway with seating.

A restaurant interior with wooden tables, chairs, and a stone wall.

A modern living room with a dark wall, a decorative light fixture, and a patterned wall art piece.

7. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

16.3 km from Oxbow Nature Center

Sarah

HK$845

HK$973 total

includes taxes & fees

3 Sept - 4 Sept

A modern indoor patio with a fire feature, seating, and large windows.

A modern hotel lobby with a large glass wall, a green wall mural, and a seating area with sofas and chairs.

A reception area with a curved reception desk, wooden shelving, and a green moss wall with the text "I ♥ EVEN".

A modern interior with a seating area, a bookshelf, and a window with a view of trees.

8. EVEN Hotel Rochester - Mayo Clinic Area by IHG

15.3 km from Oxbow Nature Center

paul

HK$823

HK$1,054 total

includes taxes & fees

12 Sept - 13 Sept

An outdoor seating area with wooden pillars, colorful striped cushions, and potted plants.

A modern restaurant with a counter, seating area, and a TV screen.

A modern hotel room with a bed, desk, and kitchenette.

An indoor swimming pool with wooden ceiling beams, yellow chairs, and tables along the sides.

9. Home2 Suites by Hilton Rochester Mayo Clinic Area

16.7 km from Oxbow Nature Center

Vickie

HK$958

HK$1,103 total

includes taxes & fees

12 Sept - 13 Sept

An outdoor seating area with a fire feature, blue cushioned chairs, and a modern building with large windows in the background.

A modern indoor pool area with lounge chairs and a pool.

A modern bar area with seating and a counter.

A modern dining area with round tables and chairs, a large painting on the wall, and a flat-screen TV mounted above a geometric-patterned wall.

10. Hyatt House Rochester/Mayo Clinic Area

16.1 km from Oxbow Nature Center

Mary Jo

HK$925

HK$1,065 total

includes taxes & fees

2 Oct - 3 Oct

A reception area with a wooden reception desk, a "Welcome to the Bread & Butter State" sign, and a "Please Center" sign.

A hotel room with a bed, a desk, a chair, a TV, and a bathroom visible through an open door.

A modern lounge area with seating arrangements, a reception desk, and a patterned wall.

A pool area with a table and chairs, a lifeguard chair, and a pool lift.

11. Hampton Inn Rochester-South

17.8 km from Oxbow Nature Center

Lynne

HK$739

HK$851 total

includes taxes & fees

1 Oct - 2 Oct

A hotel breakfast area with a self-serve station, including a waffle maker, toaster, and various food items.

A modern living room with a sofa, coffee table, and a TV mounted on a stone wall.

A hotel lobby with a patterned carpet, two beige armchairs, a small table, a clock, a fire extinguisher, and a staircase.

A hotel room with a large bed, bedside tables, a mirror, and a patterned carpet.

12. Quality Inn & Suites Mayo Clinic Area

17.8 km from Oxbow Nature Center

Cassandra

HK$600

HK$699 total

includes taxes & fees

27 Sept - 28 Sept

An indoor swimming pool with clear water, wooden flooring, and a ceiling with wooden beams and lights.

A café with multiple tables and chairs, a kitchen area with appliances, and a clock on the wall.

A room with a TV mounted on the wall, a wooden table, and two patterned armchairs.

A hotel room with two beds, a desk, a chair, a television, and a window with curtains.

13. Med City Inn & Suites - Mayo Clinic Area

14.6 km from Oxbow Nature Center

Hailey

HK$593

HK$682 total

includes taxes & fees

3 Sept - 4 Sept

A hotel room with a large round table, two sofas, a TV, and a bed.

A modern kitchen with a dark countertop, black cabinets, a microwave, and a refrigerator. There are two pendant lights above the counter.

A reception area with a clock, a counter, and a nameplate.

A hotel lobby with a reception desk, seating area, and a large window.

14. Candlewood Suites Rochester Mayo Clinic Area by IHG

17.7 km from Oxbow Nature Center

Sean

HK$909

HK$1,047 total

includes taxes & fees

5 Sept - 6 Sept

A Comfort Inn hotel with a stone facade, a covered entrance, and a parking area.

A spacious living room with a stone fireplace, blue sofas, and a flat-screen TV.

A hotel room with a blue sofa, a wooden coffee table, a bed with white linens, a TV, and a large mirror.

A spacious lobby with a central seating area, a reception desk, and a fireplace.

15. Comfort Inn & Suites West - Medical Center

11.4 km from Oxbow Nature Center

Gary

HK$672

HK$774 total

includes taxes & fees

27 Sept - 28 Sept

A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.

A compact hotel room with a kitchenette, a dining area, a sofa, and a bed.

A hotel room with a large window, a clock, a framed picture of pottery, a desk with a computer, and a seating area with patterned chairs.

A Microtel Inn & Suites building with a signboard, a parking lot, and a clear sky.

16. Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

11.9 km from Oxbow Nature Center

Siddhartha

HK$546

HK$629 total

includes taxes & fees

3 Sept - 4 Sept

A swimming pool with clear blue water, surrounded by lounge chairs and a view of residential buildings through large windows.

An outdoor patio area with wicker furniture, a central fire feature, and a stone building in the background.

A modern reception area with a brick-patterned wall, two reception desks, a flat-screen TV, and seating arrangements including a sofa and chairs.

A modern lounge area with seating, a fireplace, and a bar area.

17. Residence Inn by Marriott Rochester Mayo Clinic Area South

16.8 km from Oxbow Nature Center

Richard

HK$1,035

HK$1,191 total

includes taxes & fees

2 Oct - 3 Oct

An indoor swimming pool with slides, seating areas, and a covered section with umbrellas.

A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.

A hotel room with a kitchen area, a bed, a TV, and a seating area.

A modern kitchen with granite countertops, a built-in microwave, and a sink. There are two wooden chairs and a small table.

18. Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

15.9 km from Oxbow Nature Center

Margita

HK$774

HK$892 total

includes taxes & fees

22 Sept - 23 Sept

A restaurant with wooden tables and bar stools, a bar area with a counter, and multiple televisions mounted on the walls.

A bar with wooden stools and a neon sign.

An indoor swimming pool with a slide, seating area, and a large frog statue.

A modern kitchen with wooden cabinets, a microwave, an oven, and a dishwasher.

19. AmericInn by Wyndham Rochester Near Mayo Clinic

17.6 km from Oxbow Nature Center

Cathy

HK$617

HK$710 total

includes taxes & fees

6 Sept - 7 Sept

A poolside area with wicker chairs and potted plants, a tiled floor, and a clear view of the pool.

A hotel room with a sofa, two beds, a large window, and a framed artwork on the wall.

A reception area with a wooden reception desk, a clock, and a wall-mounted display.

A restaurant with a bar area, wooden chairs, and a stone wall.

20. Kahler Inn and Suites - Mayo Clinic Area

16 km from Oxbow Nature Center

HK$981

HK$1,129 total

includes taxes & fees

12 Sept - 13 Sept

View all properties

Compare popular hotels close to Oxbow Nature Center

Property	Property class	Guest rating
Hampton Inn & Suites Rochester-North	9.2 Wonderful 1,003 reviews	View
Brentwood Inn & Suites	8.8 Excellent 1,000 reviews	View
The Berkman	9.6 Exceptional 430 reviews	View
Econo Lodge Mayo Clinic Area	9.0 Wonderful 1,003 reviews	View
Sleep Inn & Suites West-Near Medical Center	9.0 Wonderful 696 reviews	View

Top Oxbow Nature Center Hotel Reviews

Kahler Grand Hotel

10/10 Excellent

"Awesome hot tub and pool. Great views and area. Definitely would stay here again"

Kahler Inn and Suites - Mayo Clinic Area

10/10 Excellent

"The location is so convenient- literally right across the street from Mayo. The breakfast was nice and the staff were all friendly."

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

8/10 Good

"Property was older. Doors didn’t shut from the humidity from the pool area. Not enough space in the breakfast area. Had to stand every morning."

TownePlace Suites by Marriott Rochester

10/10 Excellent

"The staff went above and beyond my expectations, they truly cared about the guests. Shova(hopefully spelled correctly) was very compassionate and understanding, knowing that many guests have family at Mayo Clinic. The hotel was amazing, great rooms, spacious, clean and comfortable. I highly recommend this hotel!"

Aspen Select

10/10 Excellent

"Very good experience. Accommodating to our needs."

Sleep Inn & Suites West-Near Medical Center

10/10 Excellent

"Excellent check-in experience. Staff member went above and beyond to help our family be in a room with a view of the fireworks."

Quality Inn near Medical Center

10/10 Excellent

"The room was very clean, and breakfast was okay"

Hotel Indigo Rochester – Mayo Clinic Area by IHG

10/10 Excellent

"This is my first time staying at Hotel Indigo. The staff was amazing. I had to keep adding nights and they were so accommodating. The room was just right. It was clean , well stocked and easy access to the Mayo Clinic. I really liked the front desk people. Super friendly and helpful. Love the attached restaurant!"

Other attractions near Oxbow Nature Center

Zollman Zoo

Visit the native and exotic animals who call Zollman Zoo home during your travels in Byron. Amble around the area's parks or experience its art scene.

See properties

Oxbow Park

8.8/10 (5 reviews)

Explore the great outdoors at Oxbow Park, a lovely green space in Byron. Visit the top-notch restaurants or cosy cafes in this walkable area.

See properties

Kalmar Town Hall

Kalmar Town Hall is just one of the places to see in Byron, so why not enjoy the other things to explore during your travels? Amble around the area's parks or experience its art scene.

See properties

Putting Green

Enjoy a round of golf in Byron at Putting Green. Amble around the area's parks or experience its art scene.

See properties

Somerby Golf Club

Enjoy a round of golf in Byron at Somerby Golf Club. Amble around the area's parks or experience its art scene.

See properties

East Brookfield Park

After visiting East Brookfield Park, make a plan to see the other sights and activities in Byron. Amble around the area's parks or experience its art scene.

See properties

Somerby Park

Somerby Park is just one of the places to see in Byron, so why not enjoy the other things to explore during your travels? Amble around the area's parks or experience its art scene.

See properties

Brook Lawn Park

After visiting Brook Lawn Park, make a plan to see the other sights and activities in Byron. Amble around the area's parks or experience its art scene.

See properties

Frequently asked questions

What's the area like around Oxbow Nature Center?

Oxbow Nature Center is located in Byron. You'll find 7 hotels and other accommodations within a few miles for a convenient home base.

What's the best place to stay close to Oxbow Nature Center?

Kahler Grand Hotel is one of the top choices for your stay based on our traveller data, and this hotel offers 2 restaurants and an indoor pool. You'll find it 10.1 mi (16.2 km) from Oxbow Nature Center. Other good choices around the area include Med City Inn & Suites - Mayo Clinic Area and Quality Inn near Medical Center.

How many hotels will I find near Oxbow Nature Center?

Expedia has 7 hotels and other accommodation options a few miles from Oxbow Nature Center.

If I need to cancel the hotel reservation for my stay near Oxbow Nature Center, will I receive a refund?

Yes, most hotel room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the best deals available near Oxbow Nature Center.

What can I see and do near Oxbow Nature Center?

If you're looking forward to a day of shopping, consider Byron Town Square, Cheery Meadows Center and High Point Shopping Center and pick out the perfect souvenir. Putting Green, Somerby Golf Club and Links of Byron Mini Golf are worth a stop while you're in the area. Zollman Zoo, Oxbow Park and Kalmar Town Hall are a few additional nearby sights.

Byron Oxbow Nature Center Hotels

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Oxbow Nature Center hotels

1. Hampton Inn & Suites Rochester-North

2. Brentwood Inn & Suites

3. The Berkman

4. Econo Lodge Mayo Clinic Area

5. Sleep Inn & Suites West-Near Medical Center

6. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

7. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

8. EVEN Hotel Rochester - Mayo Clinic Area by IHG

9. Home2 Suites by Hilton Rochester Mayo Clinic Area

10. Hyatt House Rochester/Mayo Clinic Area

11. Hampton Inn Rochester-South

12. Quality Inn & Suites Mayo Clinic Area

13. Med City Inn & Suites - Mayo Clinic Area

14. Candlewood Suites Rochester Mayo Clinic Area by IHG

15. Comfort Inn & Suites West - Medical Center

16. Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

17. Residence Inn by Marriott Rochester Mayo Clinic Area South

18. Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

19. AmericInn by Wyndham Rochester Near Mayo Clinic

20. Kahler Inn and Suites - Mayo Clinic Area

Compare popular hotels close to Oxbow Nature Center

Top Oxbow Nature Center Hotel Reviews

Kahler Grand Hotel

Kahler Inn and Suites - Mayo Clinic Area

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

TownePlace Suites by Marriott Rochester

Aspen Select

Sleep Inn & Suites West-Near Medical Center

Quality Inn near Medical Center

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Other attractions near Oxbow Nature Center

Zollman Zoo

Oxbow Park

Kalmar Town Hall

Putting Green

Somerby Golf Club

East Brookfield Park

Somerby Park

Brook Lawn Park

Frequently asked questions