Byron Oxbow Nature Center Hotels: 2026 Limited-Time Hotel Deals @Expedia

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Our top choices for Oxbow Nature Center hotels

A self-service breakfast station with a waffle maker, coffee machines, and a variety of condiments.

A reception area with a wooden reception desk, a red doormat, and framed awards on the wall.

A compact laundry area with a washing machine, dryer, and a water fountain.

A hotel lobby with leather sofas, a stone fireplace, and a patterned carpet.

1. Econo Lodge Mayo Clinic Area

18 km from Oxbow Nature Center

Ashley

HK$524

HK$603 total

includes taxes & fees

15 Nov - 16 Nov

A reception area with a wooden reception desk, a "Welcome to the Bread & Butter State" sign, and a "Please Center" sign.

A coffee station with four coffee dispensers, a stack of disposable cups, and a tray with various coffee-related items.

A modern lounge area with seating arrangements, a reception desk, and a patterned wall.

A pool area with a table and chairs, a lifeguard chair, and a pool lift.

2. Hampton Inn Rochester-South

17.8 km from Oxbow Nature Center

dennis

HK$861

HK$991 total

includes taxes & fees

1 Nov - 2 Nov

An outdoor patio area with a concrete floor, wooden fence, and string lights.

A breakfast bar with a wooden counter, a coffee machine, and a refrigerator.

A modern living room with a stone fireplace, a blue armchair, a round coffee table, and a large window offering a view of the outdoors.

3. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

14.4 km from Oxbow Nature Center

Brien

HK$946

HK$1,090 total

includes taxes & fees

6 Nov - 7 Nov

A modern indoor patio with a fire feature, seating, and large windows.

A modern interior with a seating area, a bookshelf, and a window with a view of trees.

A modern living room with a fireplace, large windows, and a flat-screen TV mounted on the wall.

A modern hotel lobby with a large glass wall, a green wall mural, and a seating area with sofas and chairs.

4. EVEN Hotel Rochester - Mayo Clinic Area by IHG

15.3 km from Oxbow Nature Center

James

HK$895

HK$1,136 total

includes taxes & fees

23 Oct - 24 Oct

A Comfort Inn hotel with a stone facade, a covered entrance, and a parking area.

A spacious living room with a stone fireplace, blue sofas, and a flat-screen TV.

A hotel room with a blue sofa, a wooden coffee table, a bed with white linens, a TV, and a large mirror.

A spacious lobby with a central seating area, a reception desk, and a fireplace.

5. Comfort Inn & Suites West - Medical Center

11.4 km from Oxbow Nature Center

Lori

HK$687

HK$791 total

includes taxes & fees

15 Nov - 16 Nov

A spacious lobby with a reception desk, sofas, and a coffee table.

A lobby with a brown sofa, yellow armchairs, a coffee table, and a clock on the wall.

An indoor swimming pool with clear blue water, surrounded by tiled flooring and equipped with a pool ladder.

A Sleep Inn hotel with a covered entrance, stone pillars, and a clear blue sky.

6. Sleep Inn & Suites West-Near Medical Center

11.3 km from Oxbow Nature Center

Jacqueline

HK$622

HK$716 total

includes taxes & fees

15 Nov - 16 Nov

An outdoor patio area with yellow umbrellas, wicker furniture, and a sign for Centerstone Plaza Hotel.

A garden with a water feature, rocks, and yellow umbrellas.

A modern reception area with a wooden reception desk, glass pendant lights, and a long hallway with seating.

A restaurant interior with wooden tables, chairs, and a stone wall.

7. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

16.3 km from Oxbow Nature Center

Christine

HK$896

HK$1,032 total

includes taxes & fees

23 Oct - 24 Oct

A swimming pool with clear blue water, surrounded by lounge chairs and a view of residential buildings through large windows.

A modern lounge area with seating, a fireplace, and a bar area.

A modern reception area with a brick-patterned wall, two reception desks, a flat-screen TV, and seating arrangements including a sofa and chairs.

An outdoor patio area with wicker furniture, a central fire feature, and a stone building in the background.

8. Residence Inn by Marriott Rochester Mayo Clinic Area South

16.8 km from Oxbow Nature Center

Chee

HK$1,036

HK$1,193 total

includes taxes & fees

13 Nov - 14 Nov

A hotel breakfast area with a self-serve station, including a waffle maker, toaster, and various food items.

A compact kitchen with a microwave, refrigerator, and coffee maker. A small bar stool is near the counter.

A hotel lobby with a patterned carpet, two beige armchairs, a small table, a clock, a fire extinguisher, and a staircase.

A modern living room with a sofa, coffee table, and a TV mounted on a stone wall.

9. Quality Inn & Suites Mayo Clinic Area

17.8 km from Oxbow Nature Center

Jessica

HK$528

HK$617 total

includes taxes & fees

13 Nov - 14 Nov

A modern kitchen with a dark countertop, black cabinets, a microwave, and a refrigerator. There are two pendant lights above the counter.

A hotel room with a large round table, two sofas, a TV, and a bed.

A reception area with a clock, a counter, and a nameplate.

A person at a checkout counter in a store, with various snack items and a sign indicating a price of $1.50.

10. Candlewood Suites Rochester Mayo Clinic Area by IHG

17.7 km from Oxbow Nature Center

Kevin

HK$950

HK$1,093 total

includes taxes & fees

28 Oct - 29 Oct

A spacious living area with a modern staircase, leather sofas, and contemporary lighting.

An outdoor seating area with blue sofas and wicker chairs, a wooden table, and green ottomans on a tiled patio.

A modern pool table in a spacious, well-lit room with large windows and a bar area.

A modern interior with a large dining table, sofas, and a kitchen area.

11. The Berkman

15 km from Oxbow Nature Center

Suzette

HK$1,595

HK$1,855 total

includes taxes & fees

22 Oct - 23 Oct

An indoor swimming pool with a dolphin sculpture, wooden ceiling, and clear windows.

A hotel reception area with a coffee station, seating area, and a fireplace.

A hotel reception area with a red 'Hello' sign, a reception desk, a coffee station, and a fireplace.

A hotel room with a large bed, two bedside tables with lamps, a telephone, and a window with sheer curtains.

12. TownePlace Suites by Marriott Rochester

11.6 km from Oxbow Nature Center

Kari

HK$769

HK$885 total

includes taxes & fees

30 Oct - 31 Oct

A restaurant with wooden tables and bar stools, a bar area with a counter, and multiple televisions mounted on the walls.

A hotel room with two beds, a desk, a chair, and a mirror.

A modern kitchen with wooden cabinets, a microwave, an oven, and a dishwasher.

A bar with wooden stools and a neon sign.

13. AmericInn by Wyndham Rochester Near Mayo Clinic

17.6 km from Oxbow Nature Center

Edward

HK$573

HK$659 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor seating area with a fire feature, blue cushioned chairs, and a modern building with large windows in the background.

A modern dining area with round tables and chairs, a large painting on the wall, and a flat-screen TV mounted above a geometric-patterned wall.

A modern indoor pool area with lounge chairs and a pool.

A modern Hyatt House hotel with a prominent 'Hyatt House' sign, multiple floors, and a parking garage.

14. Hyatt House Rochester/Mayo Clinic Area

16.1 km from Oxbow Nature Center

Elsie

HK$997

HK$1,147 total

includes taxes & fees

6 Nov - 7 Nov

A Courtyard Marriott hotel with multiple floors, a brick facade, and illuminated signage.

A hotel room with a bed, a sofa, a desk, a TV, and a wall art piece.

A modern living room with a sofa, a round coffee table, and a side table. There are large windows with a view of the outside.

A hotel room with a sofa, armchairs, a small kitchenette, a flat-screen TV, and a large window.

15. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

15 km from Oxbow Nature Center

MATTHEW

HK$887

HK$1,021 total

includes taxes & fees

6 Nov - 7 Nov

A modern outdoor seating area with a built-in fireplace, two wooden chairs, a table, and a sofa.

A modern kitchen with a central island, bar stools, and pendant lighting. A living area with a sofa, ottoman, and a view of the outdoors is visible.

A hotel room with a kitchenette, a bed, a sofa, a small table, and a window with curtains.

A modern kitchen with a built-in microwave, a coffee machine, and a sink.

16. Staybridge Suites Rochester - Mayo Clinic Area by IHG

15.3 km from Oxbow Nature Center

Amanda

HK$895

HK$1,046 total

includes taxes & fees

1 Nov - 2 Nov

A water slide with a frog theme, a pool, and a seating area with umbrellas.

A café with multiple tables and chairs, a kitchen area with appliances, and a clock on the wall.

A coffee station with a coffee machine, cups, and a Bigelow tea display.

A hotel room with two beds, a leather couch, a desk, and a bathroom visible through an open door.

17. Med City Inn & Suites - Mayo Clinic Area

14.6 km from Oxbow Nature Center

Chase

HK$593

HK$683 total

includes taxes & fees

21 Oct - 22 Oct

An indoor swimming pool with slides, seating areas, and a covered section with umbrellas.

A modern kitchen with a microwave, sink, and granite countertop.

A hotel room with a kitchen area, a bed, a TV, and a seating area.

A modern kitchen with black cabinets, white countertops, and a tiled backsplash. There are pendant lights, a refrigerator, and a coffee machine.

18. Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

15.9 km from Oxbow Nature Center

Vicky

HK$743

HK$855 total

includes taxes & fees

25 Oct - 26 Oct

A hotel lobby with a reception desk, seating area, and a bar.

A front-loading white washer and dryer in a laundry room with a window and a door.

A multi-story hotel with a grey and orange facade, a covered entrance, and a parking lot with marked spaces.

A gym with treadmills, an elliptical, and a stationary bike.

19. Super 8 by Wyndham Rochester Mayo Clinic Area

18.2 km from Oxbow Nature Center

Rick

HK$400

HK$461 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.

A reception area with a reception desk, two armchairs, a clock, and a framed artwork on the wall.

A compact hotel room with a kitchenette, a dining area, a sofa, and a bed.

A hotel room with a large window, a clock, a framed picture of pottery, a desk with a computer, and a seating area with patterned chairs.

20. Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

11.9 km from Oxbow Nature Center

John

HK$547

HK$630 total

includes taxes & fees

1 Nov - 2 Nov

View all properties

Compare popular hotels close to Oxbow Nature Center

Property	Property class	Guest rating
Econo Lodge Mayo Clinic Area	9.0 Wonderful 1,004 reviews	View
Hampton Inn Rochester-South	9.0 Wonderful 1,006 reviews	View
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys	9.6 Exceptional 748 reviews	View
EVEN Hotel Rochester - Mayo Clinic Area by IHG	9.4 Exceptional 1,007 reviews	View
Comfort Inn & Suites West - Medical Center	8.8 Excellent 663 reviews	View

Hotels recommended for families near Oxbow Nature Center

A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.

An outdoor patio area with stone walls, outdoor seating, and landscaped gardens.

A compact hotel room with a kitchenette, a bed, a TV, and a seating area.

A multi-story Staybridge Suites building with a stone facade and multiple windows.

Staybridge Suites Rochester - Commerce Dr NW by IHG

Rochester

HK$1,091

HK$1,256 total

includes taxes & fees

6 Nov - 7 Nov

A modern kitchen with dark wooden cabinets, a central island with bar stools, and pendant lighting.

A modern two-story house with a garage, a covered driveway, and a well-maintained lawn.

A kitchen with a modern design, featuring a black countertop, wooden cabinets, and a backsplash with a geometric pattern. There are two pendant lights above the sink.

A carpeted staircase with a handrail on the left and a railing on the right.

Custom Luxury Rambler in Highland Hills, Rochester

Rochester

HK$2,732

HK$4,192 total

includes taxes & fees

21 Oct - 22 Oct

A spacious lobby with a high ceiling, a central seating area with patterned sofas and ottomans, a reception desk, and a staircase leading to an upper level.

A restaurant with a staircase, dining tables, chairs, a coffee machine, and a refrigerator.

An indoor swimming pool with a wooden ceiling and large windows.

Quality Inn near Medical Center

Rochester

HK$494

HK$568 total

includes taxes & fees

9 Nov - 10 Nov

Comfort Inn & Suites West - Medical Center

Rochester

HK$687

HK$791 total

includes taxes & fees

15 Nov - 16 Nov

Sleep Inn & Suites West-Near Medical Center

Rochester

HK$622

HK$716 total

includes taxes & fees

15 Nov - 16 Nov

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

Rochester

HK$547

HK$630 total

includes taxes & fees

1 Nov - 2 Nov

TownePlace Suites by Marriott Rochester

Rochester

HK$769

HK$885 total

includes taxes & fees

30 Oct - 31 Oct

A hotel lobby with two leather armchairs, a small round table, a 'WELCOME' sign, and a 'TRASH CAN' sign on the wall.

A hotel reception area with a black reception desk, a 'WELCOME' sign, a bench, and two armchairs.

A multi-story hotel with a brick facade, a covered lobby entrance, and a parking lot with several cars.

Extended Stay America Suites Rochester North

Rochester

HK$473

HK$545 total

includes taxes & fees

31 Oct - 1 Nov

Top Oxbow Nature Center Hotel Reviews

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

10/10 Excellent

"Beautiful place to stay"

EVEN Hotel Rochester - Mayo Clinic Area by IHG

10/10 Excellent

"EVEN is our go-to hotel when visiting Rochester for doctors appointments. It’s close enough to walk and we love the clean modern rooms."

Kahler Grand Hotel

10/10 Excellent

"I love staying here because it’s attached to Mayo. I can run back to my room between appointments if needed. Parking is convenient, the hotel and rooms are clean and comfortable. I highly recommend!"

AmericInn by Wyndham Rochester Near Mayo Clinic

10/10 Excellent

"It was a great experience"

Extended Stay America Suites Rochester North

10/10 Excellent

"Me gustó que todo está muy limpio y la recepción fueron muy amables . Lo que no me gustó fue el desayuno , lo único que tenía fue café , pan y avena"

Kahler Inn and Suites - Mayo Clinic Area

10/10 Excellent

"Has been updated a bit since our last stay. Has been clean and newer items in the room. Staff always helpful. Breakfast dinning has been upgraded too! nice to see the change in the stations. Excellent to take the subway to Mayo apts. Caribou coffee downstairs, Jimmy John's, Chinese in the hotel restaurant. Have stayed here 15+ times in the past 2 years. Would recommend."

Hampton Inn & Suites Rochester-North

10/10 Excellent

"Excelente servició gracias"

Sleep Inn & Suites West-Near Medical Center

10/10 Excellent

"We love it here even have a favorite room and maid. Today we came down for breakfast and it had already ended. The staff offered to make us toast. So nice!!"

Quality Inn near Medical Center

8/10 Good

"Property seemed to be in the middle of an upgrade"

Other attractions near Oxbow Nature Center

Zollman Zoo

Visit the native and exotic animals who call Zollman Zoo home during your travels in Byron. Amble around the area's parks or experience its art scene.

See properties

Oxbow Park

8.8/10 (5 reviews)

Explore the great outdoors at Oxbow Park, a lovely green space in Byron. Visit the cosy cafes or top-notch restaurants in this walkable area.

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Kalmar Town Hall

Kalmar Town Hall is just one of the places to see in Byron, so why not enjoy the other things to explore during your travels? Amble around the area's parks or experience its art scene.

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Putting Green

Enjoy a round of golf in Byron at Putting Green. Amble around the area's parks or experience its art scene.

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Somerby Golf Club

Enjoy a round of golf in Byron at Somerby Golf Club. Amble around the area's parks or experience its art scene.

See properties

East Brookfield Park

After visiting East Brookfield Park, make a plan to see the other sights and activities in Byron. Amble around the area's parks or experience its art scene.

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Somerby Park

Somerby Park is just one of the places to see in Byron, so why not enjoy the other things to explore during your travels? Amble around the area's parks or experience its art scene.

See properties

Brook Lawn Park

After visiting Brook Lawn Park, make a plan to see the other sights and activities in Byron. Amble around the area's parks or experience its art scene.

See properties

Frequently asked questions

What's the area like around Oxbow Nature Center?

Oxbow Nature Center is located in Byron. You'll find 7 hotels and other accommodations within a few miles for a convenient home base.

What's the best place to stay close to Oxbow Nature Center?

Kahler Grand Hotel is one of the top choices for your stay based on our traveller data, and this hotel offers 2 restaurants and an indoor pool. You'll find it 10.1 mi (16.2 km) from Oxbow Nature Center. Other good choices around the area include AmericInn by Wyndham Rochester Near Mayo Clinic and Quality Inn near Medical Center.

How many hotels will I find near Oxbow Nature Center?

Expedia has 7 hotels and other accommodation options a few miles from Oxbow Nature Center.

If I need to cancel the hotel reservation for my stay near Oxbow Nature Center, will I receive a refund?

Yes, most hotel room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the best deals available near Oxbow Nature Center.

What can I see and do near Oxbow Nature Center?

If you're looking forward to a day of shopping, consider Byron Town Square, Cheery Meadows Center and High Point Shopping Center and pick out the perfect souvenir. Putting Green, Somerby Golf Club and Links of Byron Mini Golf are worth a stop while you're in the area. Oxbow Park, Zollman Zoo and Kalmar Town Hall are a few additional nearby sights.

Byron Oxbow Nature Center Hotels

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Oxbow Nature Center hotels

1. Econo Lodge Mayo Clinic Area

2. Hampton Inn Rochester-South

3. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

4. EVEN Hotel Rochester - Mayo Clinic Area by IHG

5. Comfort Inn & Suites West - Medical Center

6. Sleep Inn & Suites West-Near Medical Center

7. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

8. Residence Inn by Marriott Rochester Mayo Clinic Area South

9. Quality Inn & Suites Mayo Clinic Area

10. Candlewood Suites Rochester Mayo Clinic Area by IHG

11. The Berkman

12. TownePlace Suites by Marriott Rochester

13. AmericInn by Wyndham Rochester Near Mayo Clinic

14. Hyatt House Rochester/Mayo Clinic Area

15. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

16. Staybridge Suites Rochester - Mayo Clinic Area by IHG

17. Med City Inn & Suites - Mayo Clinic Area

18. Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

19. Super 8 by Wyndham Rochester Mayo Clinic Area

20. Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

Compare popular hotels close to Oxbow Nature Center

Hotels recommended for families near Oxbow Nature Center

Staybridge Suites Rochester - Commerce Dr NW by IHG

Custom Luxury Rambler in Highland Hills, Rochester

Quality Inn near Medical Center

Comfort Inn & Suites West - Medical Center

Sleep Inn & Suites West-Near Medical Center

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

TownePlace Suites by Marriott Rochester

Extended Stay America Suites Rochester North

Top Oxbow Nature Center Hotel Reviews

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

EVEN Hotel Rochester - Mayo Clinic Area by IHG

Kahler Grand Hotel

AmericInn by Wyndham Rochester Near Mayo Clinic

Extended Stay America Suites Rochester North

Kahler Inn and Suites - Mayo Clinic Area

Hampton Inn & Suites Rochester-North

Sleep Inn & Suites West-Near Medical Center

Quality Inn near Medical Center

Other attractions near Oxbow Nature Center

Zollman Zoo

Oxbow Park

Kalmar Town Hall

Putting Green

Somerby Golf Club

East Brookfield Park

Somerby Park

Brook Lawn Park

Frequently asked questions