Palmdale Palmdale Regional Medical Center Hotels: 2026 Limited-Time Hotel Deals @Expedia

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Our top choices for Palmdale Regional Medical Center hotels

A modern kitchen with a refrigerator, microwave, and coffee maker. There is a small dining area with a table and chairs. A wooden shelf unit is visible, and a door with a handle is on the right.

A multi-story hotel with a modern design, featuring a mix of red and beige facades, a central entrance, and a parking lot in front.

A modern kitchen with a waffle maker, refrigerated drinks, and jars of nuts and dried fruits.

A hotel room with a bed, bedside lamp, wall art, a kitchen area with appliances, and a wooden cabinet.

1. Towneplace Suites By Marriott Palmdale

1.5 km from Palmdale Regional Medical Center

Haydee

HK$894

HK$1,002 total

includes taxes & fees

4 Oct - 5 Oct

A modern living room with a stone fireplace, a flat-screen TV, and a dining area with a wooden table and chairs.

A corner market with refrigerated display cases and shelves stocked with snacks and beverages.

A modern hotel with a prominent entrance, multiple floors, and a parking lot.

A modern dining area with wooden tables and chairs, a central round table, and a kitchen counter in the background.

2. Fairfield Inn & Suites by Marriott Palmdale West

3 km from Palmdale Regional Medical Center

Cheryl

HK$760

HK$853 total

includes taxes & fees

18 Oct - 19 Oct

An outdoor patio with multiple tables and chairs, a building entrance, and large windows.

A dining area with a long table displaying various dishes, a bar area with stools, and a seating area with a sofa and chairs.

A modern hotel room with a bed, a sofa, a dining area, and a large window.

A modern living area with a sectional sofa, a coffee table, and potted plants.

3. DoubleTree by Hilton Palmdale, CA

1.1 km from Palmdale Regional Medical Center

Jessica

HK$862

HK$967 total

includes taxes & fees

9 Oct - 10 Oct

A spacious lobby with a high ceiling, a central spiral staircase, and potted plants.

A hotel with a modern architectural design, featuring a prominent entrance with a covered walkway and a flagpole with an American flag.

A spacious lobby with a central reception desk, large potted plants, and modern lighting fixtures.

An outdoor seating area with wicker furniture and a central fire feature, surrounded by plants and a brick wall.

4. Embassy Suites Palmdale

1.6 km from Palmdale Regional Medical Center

Cecilia

HK$958

HK$1,075 total

includes taxes & fees

9 Oct - 10 Oct

A modern hotel lobby with a large dining area, comfortable seating, and large windows offering a view of the outdoor patio.

A modern dining area with wooden furniture, a buffet station, and large windows offering a city view.

A modern outdoor seating area with a fire pit, surrounded by chairs, in front of a building with a pool.

A modern hotel building with a flat facade, multiple windows, and a prominent entrance with a glass canopy.

5. Element by Marriott Palmdale

1.5 km from Palmdale Regional Medical Center

HK$900

HK$1,010 total

includes taxes & fees

30 Oct - 31 Oct

A modern living room with a fireplace, leather armchairs, and a dining area in the background.

A hotel room with a bed, a sofa, a small table, a lamp, and a window with curtains.

A hotel room with a bed, a desk, a sofa, a TV, and a lamp.

An outdoor patio with a fire pit, seating area, and string lights.

6. Residence Inn by Marriott Palmdale Lancaster

2.2 km from Palmdale Regional Medical Center

Karlteris

HK$946

HK$1,060 total

includes taxes & fees

3 Oct - 4 Oct

An outdoor patio with tables and chairs, a seating area, and a view of the surrounding landscape.

A hotel reception desk with a sign reading 'Hilton Honors' and a 'Home 2 Mkt' sign above it.

A compact living space with a kitchenette, a dining area, a sofa, and a TV.

A modern hotel room with a kitchenette, a seating area with a sofa and chairs, a dining table with yellow chairs, and a large window with blinds.

7. Home2 Suites by Hilton Palmdale, CA

0.8 km from Palmdale Regional Medical Center

Carlos

HK$926

HK$1,039 total

includes taxes & fees

10 Oct - 11 Oct

A hotel lobby with a reception desk, seating area, and a bar.

A vending machine with snacks, drinks, and a Coca-Cola cooler.

An outdoor patio area with tables and chairs, shaded by large umbrellas, and a building with a modern architectural style in the background.

8. Holiday Inn Palmdale-Lancaster by IHG

0.8 km from Palmdale Regional Medical Center

Carlos Alberto

HK$690

HK$774 total

includes taxes & fees

11 Oct - 12 Oct

A modern living room with a flat-screen TV, wooden shelves with decorative items, grey upholstered seating, and a herringbone-patterned rug.

A Courtyard Marriott hotel with a covered entrance, multiple floors, and a well-lit facade.

A modern cafe with a counter, seating area, and menu boards.

A hotel room with two beds, a desk, a chair, a TV, and a window with a view of trees.

9. Courtyard by Marriott Palmdale

2.1 km from Palmdale Regional Medical Center

HK$839

HK$940 total

includes taxes & fees

4 Oct - 5 Oct

A modern hotel lobby with a central reception desk, circular ceiling lights, and a view of the outside through large glass doors.

A spacious hotel lobby with modern pendant lighting, a central island, and a view of the dining area.

A spacious lobby with high ceilings, large pillars, and modern lighting fixtures.

A reception desk with a wooden finish, a door, and framed artwork on the walls.

10. Hilton Garden Inn Palmdale

2.3 km from Palmdale Regional Medical Center

Salvador

HK$798

HK$893 total

includes taxes & fees

30 Oct - 31 Oct

A hotel with a red-tiled roof, multiple balconies, and a parking lot with several cars.

A hotel room with a large bed, two bedside tables with lamps, a TV, and a window with curtains.

A modern living room with a flat-screen TV, wooden furniture, and a kitchen area with a refrigerator and microwave.

A rooftop pool area with a hot tub, lounge chairs, and a clear view of the city skyline.

11. Best Western Plus John Jay Inn & Suites

0.5 km from Palmdale Regional Medical Center

Julio

HK$770

HK$862 total

includes taxes & fees

5 Oct - 6 Oct

A hotel room with a sofa, armchair, TV, desk, and a bed with a headboard.

A variety of food items and household goods on shelves.

A kitchen with wooden cabinets, stainless steel appliances, and a tiled backsplash.

A swimming pool with a hot tub, surrounded by palm trees and lounge chairs.

12. Staybridge Suites Palmdale by IHG

0.8 km from Palmdale Regional Medical Center

HK$729

HK$818 total

includes taxes & fees

11 Oct - 12 Oct

A modern conference room with a long table, several chairs, and a coffee station.

A hotel room with two beds, a desk, and a view of the outdoors.

A hotel with a covered entrance, palm trees, and a sign reading "Hampton Inn & Suites by Hilton".

13. Hampton Inn & Suites Palmdale

2 km from Palmdale Regional Medical Center

Blanca

HK$637

HK$730 total

includes taxes & fees

25 Oct - 26 Oct

A modern hotel with a flat roof, multiple windows, and a parking lot.

A vending machine with snacks and a digital screen displaying a waterfall.

A modern living room with a grey sofa, a grey armchair, a round coffee table, and a patterned rug. There are two floor lamps, a large window with sheer curtains, and a green accent wall with framed pictures.

14. Woodspring Suites Palmdale - Lancaster

3 km from Palmdale Regional Medical Center

Javier

HK$620

HK$695 total

includes taxes & fees

1 Oct - 2 Oct

A parking lot with a paved walkway, a white van, and a building with a 'Welcome' sign.

A multi-story motel with a parking lot, a red car parked in front, and a large tree to the right.

15. Motel 6 Palmdale, CA

0.9 km from Palmdale Regional Medical Center

Esmeralda

HK$596

HK$669 total

includes taxes & fees

30 Sept - 1 Oct

A hotel room with two beds, a desk with a TV, a bathroom mirror, and a painting on the wall.

A compact kitchen with a tiled floor, a ceiling fan, a trash bin, and a dining area with a table and chairs.

A hotel with a pool, outdoor seating, and palm trees.

A multi-story motel with balconies, a Coca-Cola sign, and a picnic table in the parking lot.

16. Palms Inn & Suites

0.8 km from Palmdale Regional Medical Center

Sayed

HK$382

HK$429 total

includes taxes & fees

11 Oct - 12 Oct

An outdoor seating area with tables and chairs, a trash bin, and a building entrance with glass doors.

A modern outdoor seating area with sofas and a coffee table, large windows, and a building facade in the background.

17. DoubleTree by Hilton Palmdale

1 km from Palmdale Regional Medical Center

HK$862

HK$967 total

includes taxes & fees

9 Oct - 10 Oct

A hotel room with two beds, a TV, a desk with a chair, a coffee maker, and a window with curtains.

A reception area with a stone wall, a Red Roof Inn sign, two leather chairs, a small table with a vase of flowers, and a potted plant.

A hotel lobby with a leather sofa, a wooden coffee table, and a red vase with flowers.

A two-story building with a red roof and a sign for Red Roof Inn.

18. Red Roof Inn Palmdale - Lancaster

1.4 km from Palmdale Regional Medical Center

Jesus

HK$533

HK$597 total

includes taxes & fees

30 Sept - 1 Oct

A hotel room with a bed, wooden headboard, a nightstand with a phone, a red and white bedspread, a red pillow, a TV, and a kitchen area with a microwave.

A balcony with a view of a parking lot, palm trees, and a building with a red roof.

A modern bathroom with a black countertop, a white sink, and a microwave.

A hotel reception area with a white brick counter, a door with a red decorative panel, and a view of the street outside.

19. Hotel Palmdale - Antelope Valley

1.8 km from Palmdale Regional Medical Center

josue

HK$541

HK$660 total

includes taxes & fees

12 Oct - 13 Oct

An outdoor patio with stone walls, a grill, a fireplace, and wicker furniture.

A modern kitchen area with a refrigerator, microwave, and coffee machine. There are tables and chairs arranged for dining.

A hotel room with two beds, a desk, chairs, and a TV.

A multi-story hotel with a stone facade, a covered entrance, and a pool area visible in the background.

20. TownePlace Suites by Marriott Lancaster, CA

11.3 km from Palmdale Regional Medical Center

Michelle

HK$946

HK$1,047 total

includes taxes & fees

9 Oct - 10 Oct

View all properties

Compare popular hotels close to Palmdale Regional Medical Center

Property	Property class	Guest rating
Towneplace Suites By Marriott Palmdale	9.6 Exceptional 41 reviews	View
Fairfield Inn & Suites by Marriott Palmdale West	9.2 Wonderful 634 reviews	View
DoubleTree by Hilton Palmdale, CA	9.2 Wonderful 952 reviews	View
Embassy Suites Palmdale	9.2 Wonderful 1,304 reviews	View
Element by Marriott Palmdale	9.2 Wonderful 763 reviews	View

Top Palmdale Regional Medical Center Hotel Reviews

Hotel Burbank

10/10 Excellent

"Perfect location for the plans we had in the area. Had everything we needed. The complementary airport shuttle was particularly helpful and appreciated. Would definitely choose this hotel again when in the area. I traveled here with my adult daughter."

Best Western Valencia/Six Flags Inn & Suites

8/10 Good

"Room was fine food next door"

Courtyard by Marriott Santa Clarita Valencia

10/10 Excellent

"I always enjoy my stay here. It's clean, it's safe, it's quiet, it's easy to get to, and the staff is always wonderful and helpful. Plus - in the afternoon they have fresh cookies! I would high recommend this place!"

Ramada by Wyndham Burbank Airport

10/10 Excellent

"Needed extra blanket. Was brought without delay. Very convenient location. Also ordered doordash and worked out great. Lots of good food choices. No restaurant onsite."

Santa Clarita Motel

10/10 Excellent

"Clean room and very nice area"

Hilton Garden Inn Valencia Six Flags

10/10 Excellent

"H"

Hyatt Regency Valencia

10/10 Excellent

"100% recommend"

Oxnard Inn Lancaster

10/10 Excellent

"There breakfast was really really goood , better than any other bigger hotel’s chain."

Huttopia Paradise Springs

8/10 Good

"We had a great stay at Huttopia Paradise Springs. Our cabin was cute, comfortable, and had everything we needed for a relaxing weekend. The property is beautiful, and we really enjoyed the peaceful atmosphere. A few things that could make the experience even better: 1. The road leading to the cabins in the farthest section of the property could use some improvement. It is quite rocky and uneven, which may be difficult for guests driving standard passenger cars. 2. The wooden deck and railings around our deck appear weathered. Some of the wood is splitting, and several members of our group got splinters from the deck and railings, even while wearing flip-flops. 3. It would be nice to have a few recreational amenities closer to the cabins that are farther from the main lodge area, such as hammocks, cornhole, table tennis etc. Overall, we had a wonderful stay and would happily return."

Frequently asked questions

What's the area like around Palmdale Regional Medical Center?

Palmdale Regional Medical Center is located in a welcoming area of Palmdale known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 32 hotels and other accommodation options you'll find within a mile.

What's the best place to stay near Palmdale Regional Medical Center?

Staybridge Suites Palmdale by IHG is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an outdoor pool. It's located just a short 0.5 mi (0.8 km) from Palmdale Regional Medical Center. Another good choice is Palms Inn & Suites, located just 0.5 mi (0.8 km) away.

How many hotels should I expect to find close to Palmdale Regional Medical Center?

Expedia has 32 hotels and other accommodation options within a mile from Palmdale Regional Medical Center.

If I need to cancel the hotel reservation for my stay near Palmdale Regional Medical Center, will I receive a refund?

Yes! The majority of room reservations are refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to get the best deals near Palmdale Regional Medical Center.

What can I see and do near Palmdale Regional Medical Center?

You can enjoy live performances at Palmdale Amphitheater and Palmdale Playhouse. If you have some time to wander around the area, you might stop by Antelope Valley Country Club, Rancho Vista Golf Club or Cinemark Antelope Valley Mall. If you want to see more of the surrounding area, you can plan a visit to Antelope Valley Mall and Palmdale City Hall.

Palmdale Palmdale Regional Medical Center Hotels

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Palmdale Regional Medical Center hotels

1. Towneplace Suites By Marriott Palmdale

2. Fairfield Inn & Suites by Marriott Palmdale West

3. DoubleTree by Hilton Palmdale, CA

4. Embassy Suites Palmdale

5. Element by Marriott Palmdale

6. Residence Inn by Marriott Palmdale Lancaster

7. Home2 Suites by Hilton Palmdale, CA

8. Holiday Inn Palmdale-Lancaster by IHG

9. Courtyard by Marriott Palmdale

10. Hilton Garden Inn Palmdale

11. Best Western Plus John Jay Inn & Suites

12. Staybridge Suites Palmdale by IHG

13. Hampton Inn & Suites Palmdale

14. Woodspring Suites Palmdale - Lancaster

15. Motel 6 Palmdale, CA

16. Palms Inn & Suites

17. DoubleTree by Hilton Palmdale

18. Red Roof Inn Palmdale - Lancaster

19. Hotel Palmdale - Antelope Valley

20. TownePlace Suites by Marriott Lancaster, CA

Compare popular hotels close to Palmdale Regional Medical Center

Top Palmdale Regional Medical Center Hotel Reviews

Hotel Burbank

Best Western Valencia/Six Flags Inn & Suites

Courtyard by Marriott Santa Clarita Valencia

Ramada by Wyndham Burbank Airport

Santa Clarita Motel

Hilton Garden Inn Valencia Six Flags

Hyatt Regency Valencia

Oxnard Inn Lancaster

Huttopia Paradise Springs

Frequently asked questions