Residence Inn Durham McPherson/Duke University Medical Center offers a refreshed retreat with practical comforts. Enjoy a to-go breakfast, relax by the lobby fireplace, and request complimentary grocery shopping. WiFi in all rooms and an area shuttle make attractions accessible.
Located in Trinity Park, a neighbourhood in Durham, Residence Inn Durham McPherson/Duke University Medical Cntr is near a train station. Durham Performing Arts Center and Sarah P. Duke Gardens are local attractions and those in the mood for shopping can visit Brightleaf Square and Northgate Mall. Looking to enjoy an event or a game while in town? See what's happening at Durham Bulls Athletic Park or Wallace Wade Stadium. Visit our Durham travel guide
1108 West Main Street, Durham, NC, 27701
What's nearby
Brightleaf Square
3 min walk - 0.3 km
Duke University
6 min walk - 0.6 km
Durham Convention Center
12 min walk - 1.1 km
Durham Bulls Athletic Park
16 min walk - 1.4 km
Durham Performing Arts Center
16 min walk - 1.4 km
Getting around
Durham Station
8 min walk
Raleigh-Durham International Airport (RDU)
21 min drive
Restaurants
Atomic Clock Brewing Co
11 min walk
Grub Durham
12 min walk
The Can Opener
7 min walk
The Federal
3 min walk
It's A Southern Thing
7 min walk
About this property
Residence Inn Durham McPherson/Duke University Medical Cntr
Hotel remodelled in 2024 and located near Duke University
Consider a stay at Residence Inn Durham McPherson/Duke University Medical Cntr and take advantage of free on-the-go breakfast, a free food/drink shopping service and a terrace. In addition to dry cleaning/laundry services and a fireplace in reception, guests can connect to free in-room WiFi.
Other perks include:
A free local area shuttle, self-parking (surcharge) and express check-out
Express check-in, luggage storage and smoke-free property
A 24-hour front desk, coffee/tea in reception and laundry services
Guest reviews say great things about the helpful staff
Room features
All 147 rooms include comforts such as laptop-friendly workspaces and air conditioning, in addition to thoughtful touches such as free WiFi and desk chairs.
More conveniences in all rooms include:
Recycling and LED light bulbs
Shower/bath combinations, free toiletries and hairdryers
32-inch Smart TVs with Netflix and premium channels
Wardrobes/cupboards, separate sitting areas and kitchens
Free on-the-go breakfast available daily 7:00 AM to 9:00 AM
Coffee and tea in common areas
Things to do
24-hour gym
Family friendly
Dining table
Free area shuttle
Grocery/convenience store
In-room full-sized refrigerator/freezer
In-room kitchen
In-room microwave
Laundry facilities
Conveniences
24-hour front desk
Free newspapers in lobby
Grocery/convenience store
Laundry facilities
Luggage storage
Safe at front desk
Guest services
Change of bedsheets (on request)
Change of towels on request
Concierge services
Dry cleaning/laundry service
Free grocery shopping service
Housekeeping (daily)
Wedding services
Business services
2,530 square feet of conference space
Business centre
Computer station
Outdoors
Terrace
Accessibility
If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
Check-in start time: 3 PM; check-in end time: midnight
Express check-in available
Minimum check-in age - 21
Check-out
Check-out before noon
Contactless check-out
Express check-out available
Special check-in instructions
Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools
Access methods
Staffed front desk
Pets
Pets are allowed for an extra charge of USD 100.00 per pet (varies based on length of stay)
Service animals are welcome, and are exempt from fees
2 total (up to 45 kg per pet)
Restrictions apply; for more information contact the property on the number on the booking confirmation
Children and extra beds
Children are welcome
Rollaway/extra beds are not available.
Cots (infant beds) are not available
Payment types at the property
Important information
Optional extras
Self-parking fee: USD 15 per day
Pet fee: USD 100.00 per pet (varies based on length of stay)
Service animals are exempt from fees
The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.
You need to know
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a carbon monoxide detector, a fire extinguisher and a smoke detector
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Marriott)
We should mention
Guests under 18 years old are not allowed in the fitness facility, and guests under 18 years old are only allowed in the swimming pool and fitness facility with adult supervision
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)
Frequently asked questions
Is Residence Inn Durham McPherson/Duke University Medical Cntr pet-friendly?
Yes, Residence Inn Durham McPherson/Duke University Medical Cntr allows pets (limit 2 total) with a maximum weight of up to 45 kg per pet. There's a fee of USD 100.00 per pet, per stay. Service animals are exempt from fees. Some restrictions may apply, so please contact the property for more details.
How much does it cost to stay at Residence Inn Durham McPherson/Duke University Medical Cntr?
As of 6 Mar 2026, prices found for a 1-night stay for 2 adults at Residence Inn Durham McPherson/Duke University Medical Cntr on 13 Mar 2026 start from HK$1,232, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.
How much is parking at Residence Inn Durham McPherson/Duke University Medical Cntr?
Self-parking is available for USD 15 per day.
What time is check-in at Residence Inn Durham McPherson/Duke University Medical Cntr?
Check-in start time: 3 PM; check-in end time: midnight.
What time is check-out at Residence Inn Durham McPherson/Duke University Medical Cntr?
Checkout is at noon.
Where is Residence Inn Durham McPherson/Duke University Medical Cntr located?
Located in Trinity Park, this hotel is within a 10-minute walk of Brightleaf Square and Duke University. Carolina Theatre and Durham Convention Center are also within 15 minutes. Durham Station is 8 minutes by foot.
Can I cancel my reservation for free and receive a full refund?
Yes, this property offers free cancellation on selected room rates because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.
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Reviews
Residence Inn Durham McPherson/Duke University Medical Cntr Reviews
9.2
Wonderful
All reviews shown are from real guest experiences. Only travellers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.More informationOpens in a new window
Staff was amazing! Breakfast had so many options, quiche, waffles, fresh fruit, sausage, hard boiled eggs…. Room was very clean. Small market store in lobby. Lobby area with a tv and tons of seating. Nice workout room. But again, staff was incredible!
We love staying here when we come to visit our family. Every stay has been wonderful. The room is very comfortable. We love the gym and the breakfasts. Having a nice laundry area on the premises is also a huge plus. The best part is the fantastic staff-everyone is so nice and helpful. Thank you for always making our trips memorable.
Clean, walking distance to gas stations and restaurants.,, decent breakfast in the morning that was free so can't complain... free hot coffee all day... spacious and well-decorated rooms with good cable and smart tvs. All around, great value for the price
A very clean and quiet hotel property with great breakfast in the morning. Ample parking and reasonably priced. All of the staff were very friendly. Would definitely recommend.
I liked the easy access to shops and food, as well as downtown and the interstate. Rooms were clean, breakfast was good (and free) and the staff were all exceptionally kind and helpful.
Ashlee
Stayed 4 nights in Jan 2024
6/10 Okay
Victor
11 Oct 2024
Liked: Property conditions & facilities
Disliked: Cleanliness
Great location. Walking distance to the event I attended which I loved but there were ants in my room.
Victor
Stayed 1 night in Oct 2024
10/10 Excellent
Kristy
20 Aug 2024
Welcoming service and walking distance to East Campus for first year move in made this a great choice.
The check in was super nice. The air conditioner was making a lot of noise - a racket. We had to complain multiple times. But they did respond 🙄 after the third vociferous complaint and replaced compressor. Friendly maintainence team , Barry the maintainence executive brought in a lot of smiles with his attitude.
The room was clean and comfortable and the gym was good. However, I gave the hotel 3 stars because the shower lets out so much water that it is actually wasting water. There's no door for the shower, so when you bathe, the water streams out of the shower and onto the bathroom floor. So much water streams out that I had to place the bathmat 12 inches away from the shower entrance so that it wouldn't get wet.