Downtown South San Francisco

San Francisco

Photo by Catherine Edejer-McCormick

Popular places to visit

Things to do


Top hotels in Downtown South San Francisco

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N

3 out of 5
20 Airport Blvd, South San Francisco, CA
The price is HK$787 per night from 26 Oct to 27 Oct
HK$787
HK$925 total
26 Oct - 27 Oct
includes taxes & fees
Stay at this 3-star business-friendly hotel in South San Francisco. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast ...
8/10 Very Good! (2,009 reviews)
"Clean room, staff very nice"

Reviewed on 2 Oct 2025

La Quinta Inn & Suites by Wyndham San Francisco Airport N
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave, San Francisco, CA
The price is HK$926 per night from 2 Nov to 3 Nov
HK$926
HK$1,090 total
2 Nov - 3 Nov
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
8.8/10 Excellent! (4,621 reviews)
"Great location!"

Reviewed on 30 Sept 2025

Holiday Inn Golden Gateway by IHG
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St, San Francisco, CA
The price is HK$842 per night from 2 Nov to 3 Nov
HK$842
HK$992 total
2 Nov - 3 Nov
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...
8.6/10 Excellent! (1,829 reviews)
"Conveniently location close to China town and financial centre."

Reviewed on 1 Oct 2025

Hilton San Francisco Financial District
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St, San Francisco, CA
The price is HK$1,101 per night from 5 Nov to 6 Nov
HK$1,101
HK$1,616 total
5 Nov - 6 Nov
includes taxes & fees
Book a stay at this eco-certified hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (6,898 reviews)
"Nice upgrade, clean room, friendly staff, wonderful breakfast, fantastic location."

Reviewed on 1 Oct 2025

Hotel Riu Plaza Fisherman's Wharf
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

4 out of 5
424 Clay St, San Francisco, CA
The price is HK$1,081 per night from 18 Oct to 19 Oct
HK$1,081
HK$1,273 total
18 Oct - 19 Oct
includes taxes & fees
Stay at this 4-star business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
8.8/10 Excellent! (2,653 reviews)
"Conveniently walkable to Chinatown and financial district"

Reviewed on 30 Sept 2025

Club Quarters Hotel in San Francisco
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St, San Francisco, CA
The price is HK$1,541 per night from 11 Oct to 12 Oct
HK$1,541
HK$1,814 total
11 Oct - 12 Oct
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the pool and ...
8.8/10 Excellent! (2,731 reviews)
"Wonderful staff! Very friendly and willing to help with anything we needed. The hotel was clean, in the perfect area to explore San Francisco, cable car was just out the door."

Reviewed on 6 Oct 2025

Handlery Union Square Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Downtown South San Francisco

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Excelsior

Though Excelsior may not have many top sights, you can venture to the surrounding area to see attractions like Cow Palace and San Bruno Mountain State Park.

Excelsior
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Noe Valley

Appreciated for its churches and architecture, you might consider exploring Noe Valley. Check out the variety of things to see and do like 22nd St Hill, and jump on the metro at Church St & Clipper St Stop or Church St & 24th St Stop to get around the city.

Noe Valley
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Mission District

3.5/5(11 area reviews)

You might enjoy the bars while in Mission District. San Francisco Public Library is a notable sight, and you can get around town at 16th Street Mission Station or 24th Street Mission Station to see more of the city.

Mission District
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Potrero Hill

The live music and architecture are just a few things visitors like about Potrero Hill. San Francisco Bay and Letterform Archive are worthwhile spots to check out, and you can hop on the metro at 20th Street Station or 23rd Street Station to get around the larger area.

Potrero Hill
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Sunset District

3.5/5(6 area reviews)

Consider exploring the beaches in Sunset District. If sightseeing is on the list, Ocean Beach is a top attraction. Hop on the metro at Judah Street & Sunset Boulevard Station or Judah St & 34th Ave Stop to see more of the area.

Sunset District
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Mission Bay

While you're in Mission Bay, take in top sights like Chase Center or Lefty O'Doul Bridge, and hop on the metro to see more of the city at Mission Rock Station or UCSF/Chase Center Stop.

Mission Bay


Downtown South San Francisco