Santa Ana hotels in Panama City

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Our top choices for Santa Ana hotels

Hostal La Cigarra

Hostal La Cigarra
2.0 star property
Santa Ana
7.6 out of 10, Good, (71 reviews)
"Excellent staff, close to metro and embassies. A good location, good room for a great price. I would stay again. "
United Kingdom
Mark
The price is HK$244
HK$268 total
includes taxes & fees
2 Jun - 3 Jun
Hostal La Cigarra

Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana
9.0 out of 10, Wonderful, (97 reviews)
"Always an amazing stay"
United States
chris
The price is HK$697
HK$1,002 total
includes taxes & fees
2 Jun - 3 Jun
Casco View Apartments

Hotel Riazor

Hotel Riazor
3.0 star property
Santa Ana
3.8 out of 10, (11 reviews)
"Rough neighborhood "
Canada
Del
Hotel Riazor

Hotel República

Hotel República
2.0 star property
Santa Ana
6.8 out of 10, (194 reviews)
"Very good ."
United States
Denice
The price is HK$229
HK$722 total
includes taxes & fees
2 Jun - 3 Jun
Hotel República

La Manzana Barrio Vivo by Wynwood

La Manzana Barrio Vivo by Wynwood
3.0 star property
Santa Ana
7.4 out of 10, Good, (17 reviews)
"Very clean and safe property"
United States
Javier Alberto Lindauer
The price is HK$536
HK$805 total
includes taxes & fees
2 Jun - 3 Jun
La Manzana Barrio Vivo by Wynwood

ART CASCO The Hotel

ART CASCO The Hotel
2.0 star property
Santa Ana
6.0 out of 10, (11 reviews)
"Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best"
United States
Eldris
ART CASCO The Hotel

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
21.1 km from Santa Ana
8.6 out of 10, Excellent, (2,568 reviews)
"Great place to stay, restaurant is great also"
United States
Janet
The price is HK$995
HK$1,147 total
includes taxes & fees
14 Jun - 15 Jun
Crowne Plaza Panama Airport by IHG

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
19.8 km from Santa Ana
8.4 out of 10, Very good, (1,825 reviews)
"This hotel is very clean and the Staff are very friendly."
United States
Doreen
The price is HK$857
HK$943 total
includes taxes & fees
18 Jun - 19 Jun
Riande Aeropuerto Hotel & Casino

ORHO Hotel Boutique 15 Minutes from PTY Airport

ORHO Hotel Boutique 15 Minutes from PTY Airport
2.0 star property
20.5 km from Santa Ana
8.8 out of 10, Excellent, (131 reviews)
"Lovely property, staff was always smiling and it's close to restaurants."
United States
Luis
The price is HK$801
HK$1,040 total
includes taxes & fees
2 Jun - 3 Jun
ORHO Hotel Boutique 15 Minutes from PTY Airport

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
14.7 km from Santa Ana
9.0 out of 10, Wonderful, (1,003 reviews)
"Always a pleasure to stay here"
United States
Rory
The price is HK$972
HK$1,069 total
includes taxes & fees
6 Jun - 7 Jun
Courtyard by Marriott Panama Metromall

Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
4.5 star property
Amador, 2.3 km from Santa Ana
8.6 out of 10, Excellent, (1,006 reviews)
"Excellent location, good parking."
United States
Mark
The price is HK$670
HK$737 total
includes taxes & fees
9 Jun - 10 Jun
Radisson Hotel Panama Canal

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este, 10.2 km from Santa Ana
9.2 out of 10, Wonderful, (294 reviews)
"Everything was amazing"
United States
James
The price is HK$737
HK$1,224 total
includes taxes & fees
7 Jun - 8 Jun
Arcadia Condo Suites

Villa Caprichosa

Villa Caprichosa
2.5 star property
18.3 km from Santa Ana
9.8 out of 10, Exceptional, (71 reviews)
"Really good food, nice staff it was the best service! "
United States
junier
The price is HK$1,254
HK$1,379 total
includes taxes & fees
3 Jun - 4 Jun
Villa Caprichosa

The Beach House

The Beach House
3.0 star property
Amador, 4.8 km from Santa Ana
8.4 out of 10, Very good, (433 reviews)
"Everting was clean and good nice place to stay "
United States
Kristine
The price is HK$583
HK$641 total
includes taxes & fees
3 Jun - 4 Jun
The Beach House

Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
4.0 star property
El Cangrejo, 3.5 km from Santa Ana
8.8 out of 10, Excellent, (945 reviews)
"Breakfast was great, rooms very clean"
United States
juanita
The price is HK$458
HK$892 total
includes taxes & fees
2 Jun - 3 Jun
Waymore Hotel Spa & Casino

The Executive Hotel

The Executive Hotel
3.5 star property
Campo Alegre, 3.2 km from Santa Ana
9.2 out of 10, Wonderful, (1,122 reviews)
"It was a nice stay and breakfast is delicious"
United States
Susana
The price is HK$695
HK$765 total
includes taxes & fees
17 Jun - 18 Jun
The Executive Hotel

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz, 12.7 km from Santa Ana
9.6 out of 10, Exceptional, (698 reviews)
"Breakfast was exceptional, everything you could think of was available. The spa was great and the staff 10/10"
United States
Aeon
The price is HK$1,875
HK$2,062 total
includes taxes & fees
12 Jun - 13 Jun
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco, 5.7 km from Santa Ana
8.6 out of 10, Excellent, (1,003 reviews)
"Very well maintained and beautiful place."
United States
Simon
The price is HK$1,051
HK$1,156 total
includes taxes & fees
13 Jun - 14 Jun
Sheraton Grand Panama

MARINN Tropical Vibes Hotel

MARINN Tropical Vibes Hotel
3.5 star property
Amador, 4.8 km from Santa Ana
8.0 out of 10, Very good, (255 reviews)
"The breakfast was good and lots of parking in a safe place "
United States
Tessa
The price is HK$608
HK$669 total
includes taxes & fees
8 Jun - 9 Jun
MARINN Tropical Vibes Hotel

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
Punta Paitilla, 3.4 km from Santa Ana
9.4 out of 10, Exceptional, (2,165 reviews)
"We enjoy this property. We have stayed here a few times and enjoy the location, the relaxing pool area and the beakfast."
United States
James
The price is HK$809
HK$890 total
includes taxes & fees
19 Jun - 20 Jun
Plaza Paitilla Inn Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Santa Ana

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, pool loungers
Casco View Apartments
3.5 star property
9.0
Wonderful
97 reviews
View
Bar (on property)
Hostal La Cigarra
2.0 star property
7.6
Good
71 reviews
View
Iron/ironing board, free WiFi, bed sheets
La Manzana Barrio Vivo by Wynwood
3.0 star property
7.4
Good
17 reviews
View
Beach shuttle
Hotel República
2.0 star property
6.8
194 reviews
View
Front of property
ART CASCO The Hotel
2.0 star property
6.0
11 reviews
View

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Calidonia

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Via Espana.

Top Santa Ana Hotel Reviews

Frequently asked questions

What's it like in Santa Ana?
Santa Ana is a neighbourhood that travellers like for its seafood restaurants, shopping and parks. Are you looking for Santa Ana travel tips? Make sure that you visit Avenida Balboa and El Machetazo Santa Ana while you're in the neighbourhood.
Where is the best hotel for a stay in Santa Ana?
Based on our traveller data, Casco View Apartments is one of the top choices for your stay in Santa Ana. This condo is a short 8-minute walk from Avenida Balboa, and it offers an outdoor pool and in-room kitchens.
How many hotels can I expect to find in Santa Ana?
Expedia has 117 hotels and other accommodation options in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Santa Ana.
What is there to do in this Panama City neighbourhood?
If you're looking forward to a day of shopping in Santa Ana, consider El Machetazo Santa Ana or Avenida Balboa, and pick out the perfect souvenir. When you're sightseeing in Panama City, Albrook Shopping Mall and Avenida Central are also worth a stop.