A colonial-style building with a bell tower, palm trees, and a paved walkway.

Santa Cruz hotels from HK$194

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Check prices for these dates

Tonight
24 Sept - 25 Sept
Tomorrow
25 Sept - 26 Sept
This weekend
25 Sept - 27 Sept
Next weekend
2 Oct - 4 Oct

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Our top choices for Santa Cruz hotels

1. Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Equipetrol
United States
Daniel
HK$1,127
HK$1,127 total
11 Oct - 12 Oct
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

2. Sun Hotel

Sun Hotel
Santa Cruz
United States
Ivan
HK$847
HK$847 total
25 Sept - 26 Sept
Sun Hotel

3. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Santa Cruz
United States
Scott
HK$577
HK$577 total
3 Oct - 4 Oct
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

4. Lido Hotel

Lido Hotel
Centro Histórico
United States
Gabrielle
HK$194
HK$194 total
27 Sept - 28 Sept
Lido Hotel

5. Camino Real Hotel

Camino Real Hotel
Santa Cruz
United States
Wendy
HK$1,264
HK$1,264 total
11 Oct - 12 Oct
Camino Real Hotel

6. Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra
Equipetrol
United States
Hui Hua
HK$343
HK$343 total
16 Oct - 17 Oct
Ibis Santa Cruz DE LA Sierra

7. TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz
Equipetrol
United States
Pluetina
HK$684
HK$684 total
27 Sept - 28 Sept
TRYP by Wyndham Santa Cruz

8. Hotel G

Hotel G
Santa Cruz
Mexico
JACOB
HK$214
HK$214 total
23 Oct - 24 Oct
Hotel G

9. HOTEL OSHO

HOTEL OSHO
Santa Cruz
Canada
David
HK$369
HK$369 total
1 Oct - 2 Oct
HOTEL OSHO

10. Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel
Santa Cruz
United States
Deivis
HK$830
HK$830 total
3 Oct - 4 Oct
Marriott Santa Cruz de la Sierra Hotel

11. Chairú Eco Hotel

Chairú Eco Hotel
Santa Cruz
United States
Luis
HK$387
HK$387 total
1 Oct - 2 Oct
Chairú Eco Hotel

12. Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
Santa Cruz
United States
Luisa
HK$361
HK$361 total
30 Sept - 1 Oct
Premium Suites Deluxe Aparthotel Equipetrol

13. Delfines Collection Hotel By Mercure

Delfines Collection Hotel By Mercure
Equipetrol
United Kingdom
Mathetes
HK$374
HK$374 total
8 Oct - 9 Oct
Delfines Collection Hotel By Mercure

14. Hotel Cortez

Hotel Cortez
Equipetrol
United States
Leonora
HK$1,020
HK$1,020 total
9 Oct - 10 Oct
Hotel Cortez

15. Hotel LP Equipetrol

Hotel LP Equipetrol
Equipetrol
United States
Ricardo
HK$378
HK$417 total
16 Oct - 17 Oct
Hotel LP Equipetrol

16. Hotel Las Américas

Hotel Las Américas
Centro Histórico
Canada
Stanley
HK$205
HK$205 total
28 Sept - 29 Sept
Hotel Las Américas

17. Hotel Pascana centro

Hotel Pascana centro
Centro Histórico
HK$424
HK$424 total
28 Sept - 29 Sept
Hotel Pascana centro

18. Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
Santa Cruz
United States
Ruben
HK$212
HK$212 total
27 Sept - 28 Sept
Apart Hotel Premium Suites Santa Cruz

19. Swissôtel Santa Cruz De La Sierra

Swissôtel Santa Cruz De La Sierra
Santa Cruz
United States
GONZALO
HK$1,029
HK$1,029 total
14 Oct - 15 Oct
Swissôtel Santa Cruz De La Sierra

20. Cosmopolitano Hotel Boutique

Cosmopolitano Hotel Boutique
Centro Histórico
United States
Veronica
HK$451
HK$451 total
3 Oct - 4 Oct
Cosmopolitano Hotel Boutique
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Holiday Rentals in Santa Cruz

Aparthotel

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
Santa Cruz
"great place to stay!"
Premium Suites Deluxe Aparthotel Equipetrol
Apartment

Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
Santa Cruz
"Great location."
Apart Hotel Premium Suites Santa Cruz
Aparthotel

Terranova Suites

Terranova Suites
Santa Cruz
"Easy to access"
Terranova Suites
Aparthotel

Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel
Santa Cruz
"Perfect hotel"
Equipetrol Suites Apart Hotel
Apartment

AMERICA APARTMENTS

AMERICA APARTMENTS
Santa Cruz
"Clean room, great staff "
AMERICA APARTMENTS
Aparthotel

Apart Hotel Toborochi

Apart Hotel Toborochi
Equipetrol
"Very comfortable and quiet place and very good location. "
Apart Hotel Toborochi
Holiday Home

Casa Vida

Casa Vida
Santa Cruz
"buena recepción, el lugar es muy bueno un poco alejado de la ciudad, falta comodidad en algunos aspectos pero la casa es grande y espaciosa"
Casa Vida
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Where to stay in Santa Cruz

Find the best Santa Cruz areas for the activities you enjoy most.Learn more about Santa Cruz
Learn more about Santa Cruz

Equipetrol

When in Equipetrol, you can plan a visit to Santa Cruz Zoo and Ventura Mall, some noteworthy sights in the nearby area.

Centro Histórico

If you're spending some time in Centro Histórico, Plaza 24 de Septiembre and La Recova Artisan Walk are top sights worth seeing.

Hamacas

When in Hamacas, you can plan a visit to Las Brisas Shopping Center and Santa Cruz Zoo, some noteworthy sights in the nearby area.

Zona Sur (South Zone)

Though Zona Sur (South Zone) may not have many top sights, you can venture to the surrounding area to see attractions like Ramon Tahuichi Aguilera Stadium and Plaza 24 de Septiembre.

Urubó

While there might not be top attractions in Urubó, you can explore the larger area and discover places like Guembe Biocenter and Ventura Mall.

Stay near popular Santa Cruz attractions

A historic building with arched windows and a clock. People are sitting and standing on the steps in front of the building.

Plaza 24 de Septiembre

8.8/10 (164 reviews)
Plaza 24 de Septiembre buzzes with local culture beneath swaying palms and colonial architecture. Climb the Cathedral's bell tower for spectacular city views while sampling authentic Bolivian coffee from vendors.
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An interior of a church with high arched ceilings, wooden pews, and a central altar.

San Lorenzo Cathedral

9.0/10 (84 reviews)
This grand neoclassical cathedral dominates Santa Cruz's skyline with its towering spires and ornate façade. Climb the bell tower at sunset for breathtaking panoramic views of the city.
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Ventura Mall

9.0/10 (183 reviews)
Ventura Mall, Santa Cruz's premier shopping destination, features international brands and local boutiques. Enjoy the cinema complex, food court, and entertainment options in this contemporary Bolivian retail hub.
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Guembe Biocenter

8.8/10 (60 reviews)
This vibrant ecological sanctuary showcases hundreds of butterfly species in a lush, tropical environment. Explore walking trails, enjoy boat rides, and learn about biodiversity in this serene natural retreat.
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Santa Cruz Zoo

8.4/10 (53 reviews)
The Santa Cruz Municipal Zoo showcases Bolivia's native wildlife in naturalistic habitats, featuring jaguars, tapirs, and free-ranging sloths. Morning visits offer the best chance to see active animals.
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Las Brisas Shopping Center

8.4/10 (40 reviews)
This modern complex offers 80+ stores, a nine-screen cinema, and a unique outdoor restaurant promenade. Explore the gastronomic boulevard for dining experiences beyond the standard food court options.
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Ramon Tahuichi Aguilera Stadium

8.4/10 (18 reviews)
This multi-purpose stadium hosts Bolivia's most passionate football rivalries and tournaments. Experience the electric atmosphere of a local derby while enjoying modernised facilities and vibrant Santa Cruz culture.
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Arenal Park

7.4/10 (16 reviews)
After visiting Arenal Park, make a plan to see the other sights and activities in Santa Cruz. While in the area, you can find time to visit its shops.
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Learn more about Santa Cruz

Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

See all hotels in Santa Cruz
A colonial-style building with a bell tower, palm trees, and a paved walkway.

Top Santa Cruz Hotel Reviews

Hotel Cortez

Hotel Cortez

8/10 Good
"Clean room but it was not fully ready for me when I arrived."
Shawna 1-night trip
Posted 2 hours ago
Hotel Cortez
Camino Real Hotel

Camino Real Hotel

10/10 Excellent
"The hotel is always as expected. Very clean rooms. Staff is great. Close to shopping. Delicious breakfast menu"
Christina 3-night trip
Posted 9 days ago
Camino Real Hotel
Sun Hotel

Sun Hotel

10/10 Excellent
"Very nice place to stay. Close to the airport with shuttle to the hotel."
Richard 1-night trip
Posted 2 weeks ago
Sun Hotel
TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz

10/10 Excellent
"We had a great stay here. The rooms were clean and comfortable. Will return!"
Lana 1-night trip
Posted 2 weeks ago
TRYP by Wyndham Santa Cruz
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

10/10 Excellent
"The room was very clean and the breakfast was fantastic. Overall it was a great experience."
Scott 7-night trip
Posted 3 weeks ago
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra

10/10 Excellent
"All around good price and location"
Alejandro 1-night trip
Posted 1 month ago
Novotel Santa Cruz De La Sierra
HOTEL OSHO

HOTEL OSHO

10/10 Excellent
"Good"
Nando 8-night trip
Posted 1 month ago
HOTEL OSHO
Delfines Collection Hotel By Mercure

Delfines Collection Hotel By Mercure

10/10 Excellent
"Todo muy bien"
lady 2-night trip
Posted 2 months ago
Delfines Collection Hotel By Mercure
Hotel LP Equipetrol

Hotel LP Equipetrol

8/10 Good
"El cuarto agradable, pero faltó servicio de ayuda para subir y bajar maletas, también servicio adecuado de taxi para moverse en Santa Cruz"
José Bernardo 1-night trip
Posted 3 months ago
Hotel LP Equipetrol

More cheap stays in Santa Cruz

Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel

Equipetrol Santa Cruz Departamento de Santa Cruz
HK$403
HK$403 total
25 Sept - 26 Sept
Equipetrol Suites Apart Hotel
Ibiza Hostel

Ibiza Hostel

445 Santa Cruz Departamento de Santa Cruz
Get ratesIbiza Hostel
Amaca Hostal

Amaca Hostal

249 Independencia Santa Cruz Departamento de Santa Cruz
Get ratesAmaca Hostal
Casa Por Temporadas

Casa Por Temporadas

Barrio Las Pampitas, calle 3 Nro. 99 Santa Cruz Santa Cruz Department
Get rates
10/10 Exceptional! (1 review)
Casa Por Temporadas
HOTEL CASA BLANCA

HOTEL CASA BLANCA

Avenida Marcelo Terceros Zona Equipetrol Santa Cruz Santa Cruz de la Sierra
Get ratesHOTEL CASA BLANCA
Hotel Viru Viru II

Hotel Viru Viru II

Av. Alameda 72 - Zona Valle Sanchez Santa Cruz Santa Cruz de la Sierra
Get rates
4.8/10 (3 reviews)
Hotel Viru Viru II

Frequently asked questions

What's the best place for a stay in Santa Cruz?
Ibis Santa Cruz DE LA Sierra is one of the top choices for your stay based on our traveller data. This hotel offers a restaurant and free parking. Other good choices for your stay include Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Marriott Santa Cruz de la Sierra Hotel. See all available top hotels, or vacation rentals in Santa Cruz.
What are some of the best holiday rentals that Santa Cruz has to offer?
Casa Vida: This highly rated holiday home rental in Santa Cruz is located in a rural location, and has an outdoor pool, a patio and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a full-sized fridge, a stovetop and a microwave, so that you can cook with friends or family. Kick off your shoes and enjoy yourself with a private garden and a selection of games. Some other homes for rent in Santa Cruz include Cozy 1-bedroom house in beautiful Santa Cruz de la Sierra with WiFi, AC and Seasonal House. See all vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
What's the best budget-friendly accommodation in Santa Cruz?
Based on our traveller reviews, residencial francia - Hostel is a top choice for a less expensive stay. Other choices for your budget-friendly stay include Residencial Ikandire II and Nomad Hostel. View all budget hotels in Santa Cruz.
What's the best family accommodation in Santa Cruz?
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a hotel with 2 restaurants and free parking, and it's a top choice on Expedia for families. Other choices for your child-friendly holiday include Marriott Santa Cruz de la Sierra Hotel and Camino Real Hotel. Also, attractions such as Santa Cruz Zoo and Play Land Amusement Park are fun for children of all ages. Find more child-friendly accommodations in Santa Cruz.
What's the best LGBTQ-friendly accommodation in Santa Cruz?
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. Hotel Pascana centro and Swissôtel Santa Cruz De La Sierra are other good choices for your holiday. See all available hotels listed as LGBTQ-friendly in Santa Cruz.
What's the best dog-friendly accommodation option in Santa Cruz?
Casa Por Temporadas is a top dog-friendly guest house, and offers an outdoor pool along with in-room kitchens for its human guests. Two other good options for you and your pet's trip include Ibis Santa Cruz DE LA Sierra and Hotel LP Equipetrol. See more pet-friendly hotel accommodations in Santa Cruz.
What's the best luxury accommodation option in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a luxury hotel with a full-service spa and a rooftop terrace, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Camino Real Hotel and Hampton by Hilton Santa Cruz/Equipetrol, Bolivia are other upscale choices for your holiday. Find more luxury hotels in Santa Cruz.
What are some accommodation options with pools in Santa Cruz?
Yotau All Suites Hotel is a top hotel with 2 outdoor swimming pools, a children's pool and 2 restaurants. A couple of other options that feature an on-site pool include Gran Hotel Santa Cruz and Buganvillas Hotel Suites & Spa. View all hotels with pools in Santa Cruz.
What is the best spa hotel in Santa Cruz?
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a top spa hotel featuring a fitness centre, a hair salon and a bar. Enjoy a facial, body scrub or hydrotherapy at Los Tajibos Club Spa. Other popular spa hotels in Santa Cruz include Marriott Santa Cruz de la Sierra Hotel and Camino Real Hotel. See all spa hotels in Santa Cruz.
What's the best hotel in Santa Cruz with an on-site water park or a water park nearby?
Gran Hotel Santa Cruz is a popular hotel, featuring free water park access, an outdoor pool and a restaurant. Take a look at all hotels with or near waterparks in Santa Cruz.
What's it like to stay in Santa Cruz?
Visitors to Santa Cruz will definitely enjoy the shopping. Tourists can also enjoy the city's cafés, zoo and cathedral. In Santa Cruz, there are 310 hotels and other accommodation options to choose from. Find out more about Santa Cruz.
What is there to see in Santa Cruz?
Cultural venues include Ethno-folkloric Museum, Cine Center and Sacred Art Museum. Landmarks like San Lorenzo Cathedral, Plaza 24 de Septiembre and Blacutt Square might be worth a visit. Natural beauty is on display at Arenal Park, Guembe Biocenter and Lomas de Arena Regional Park. Take a look at what more there is to see and do in Expedia's Santa Cruz guide.
How should I get around Santa Cruz?
If you want to venture outside the area, hop on a train at Santa Cruz de la Sierra Station. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.
What's the weather like in Santa Cruz?
The hottest months are usually October and November, with an average temperature of 26°C, while the coldest months are June and July, with an average of 21°C. Average annual precipitation for Santa Cruz is 1208 mm.