Sioux Falls Sioux Empire Medical Museum Hotels

Start date: Check-in selected.
To Date
End date: Check-out

    Change your mind

    Book hotels with free cancellation

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
24 Oct - 25 Oct
Tomorrow
25 Oct - 26 Oct
This weekend
24 Oct - 26 Oct
Next weekend
31 Oct - 2 Nov

Filter by

Guest rating
Guest rating
Star rating

Top Trending Hotels Near Sioux Empire Medical Museum

Terrace/patio
Home2 Suites By Hilton Sioux Falls/Sanford Medical Center
Home2 Suites By Hilton Sioux Falls/Sanford Medical Center
3.0 star property
9.4 out of 10, Exceptional, (563)
"The cleanest hotel I’ve been to. Very quiet and nice. "
United States
Katherine
The price is HK$1,019
HK$1,134 total
includes taxes & fees
30 Oct - 31 Oct
Home2 Suites By Hilton Sioux Falls/Sanford Medical Center
Interior detail
Hotel On Phillips
Hotel On Phillips
2.5 star property
9.6 out of 10, Exceptional, (1245)
"Beautiful hotel."
United States
Amy
Hotel On Phillips
Free daily continental breakfast
Clubhouse Hotel Suites Sioux Falls
Clubhouse Hotel Suites Sioux Falls
3.0 star property
9.6 out of 10, Exceptional, (1001)
"Clean, friendly staff, great breakfast"
United States
Jennifer
Clubhouse Hotel Suites Sioux Falls
Meeting facility
Canopy By Hilton Sioux Falls Downtown
Canopy By Hilton Sioux Falls Downtown
4.0 star property
9.4 out of 10, Exceptional, (136)
"Great hotel"
United States
BRIAN
The price is HK$1,190
HK$1,352 total
includes taxes & fees
23 Nov - 24 Nov
Canopy By Hilton Sioux Falls Downtown
Living area
Hilton Garden Inn Sioux Falls Downtown
Hilton Garden Inn Sioux Falls Downtown
3.0 star property
9.0 out of 10, Wonderful, (875)
"Under construction but staff adapted and accommodated very well. Room was clean and quiet. Perfect location "
United States
Joseph
The price is HK$1,080
HK$1,231 total
includes taxes & fees
23 Nov - 24 Nov
Hilton Garden Inn Sioux Falls Downtown
Porch
Historic Victorian Inn
Historic Victorian Inn
3.0 star property
8.8 out of 10, Excellent, (56)
"It was a great place to stay and super interesting."
United States
Kathy
The price is HK$1,026
HK$1,253 total
includes taxes & fees
6 Nov - 7 Nov
Historic Victorian Inn
Exterior
Holiday Inn Express & Suites Sioux Falls At Empire Mall by IHG
Holiday Inn Express & Suites Sioux Falls At Empire Mall by IHG
2.5 star property
8.8 out of 10, Excellent, (1000)
"Really enjoyed the stay and nice staff "
United States
jenny
The price is HK$902
HK$1,005 total
includes taxes & fees
22 Nov - 23 Nov
Holiday Inn Express & Suites Sioux Falls At Empire Mall by IHG
Exterior
Country Inn & Suites by Radisson, Sioux Falls, SD
Country Inn & Suites by Radisson, Sioux Falls, SD
3.0 star property
8.4 out of 10, Very good, (1122)
"Mostly Clean.. Great views of River.. Pretty decent restaurant on site. Would stay there again for sure."
United States
Todd
The price is HK$786
HK$878 total
includes taxes & fees
23 Nov - 24 Nov
Country Inn & Suites by Radisson, Sioux Falls, SD
Exterior
Holiday Inn Sioux Falls-City Centre by IHG
Holiday Inn Sioux Falls-City Centre by IHG
3.0 star property
8.4 out of 10, Very good, (1001)
"Always a great stay. "
United States
Shawn
The price is HK$645
HK$723 total
includes taxes & fees
23 Nov - 24 Nov
Holiday Inn Sioux Falls-City Centre by IHG
Lobby
Sheraton Sioux Falls Hotel & Convention Center
Sheraton Sioux Falls Hotel & Convention Center
4.0 star property
8.6 out of 10, Excellent, (1002)
"I love staying at this property. Very warm and welcoming staff and love the rooms."
United States
Amber
The price is HK$852
HK$950 total
includes taxes & fees
2 Nov - 3 Nov
Sheraton Sioux Falls Hotel & Convention Center
Free daily continental breakfast
The Center Inn
The Center Inn
2.5 star property
8.4 out of 10, Very good, (674)
"Quite place to stay staff was very friendly beds comfortable and rooms were clean. "
United States
Tina
The Center Inn
Desk, free WiFi, wheelchair access
Valley Inn
Valley Inn
2.5 star property
7.6 out of 10, Good, (1003)
"Great place tonstay"
United States
Lisa
Valley Inn
3 indoor pools, open 9:00 AM to 10:00 PM, pool loungers
Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr
Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr
3.0 star property
7.6 out of 10, Good, (1404)
"The hotel was great!"
United States
ROLAND
The price is HK$465
HK$526 total
includes taxes & fees
4 Nov - 5 Nov
Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr
Dining room
Historic Twin Tudors Inn
Historic Twin Tudors Inn
3.0 star property
8.8 out of 10, Excellent, (3)
"Lovely place! Wish we could have stayed longer. Steve was attentive and helpful. "
United States
Anonymous traveller
Historic Twin Tudors Inn
Lobby
Ramada by Wyndham Sioux Falls
Ramada by Wyndham Sioux Falls
2.0 star property
5.4 out of 10, (1001)
"Close to I 29"
United States
David
The price is HK$410
HK$465 total
includes taxes & fees
2 Nov - 3 Nov
Ramada by Wyndham Sioux Falls
Terrace/patio
Hyatt Place Sioux Falls South
Hyatt Place Sioux Falls South
3.0 star property
9.4 out of 10, Exceptional, (1020)
"Comfortable bed after a long trip, breakfast is good, I like the location"
United States
Dulce ann
The price is HK$909
HK$1,013 total
includes taxes & fees
2 Nov - 3 Nov
Hyatt Place Sioux Falls South
Exterior
Holiday Inn & Suites Sioux Falls - Airport by IHG
Holiday Inn & Suites Sioux Falls - Airport by IHG
3.0 star property
9.2 out of 10, Wonderful, (820)
"Loved that we got a free breakfast meal voucher for the restaurant attached!"
United States
Makella
The price is HK$800
HK$894 total
includes taxes & fees
23 Nov - 24 Nov
Holiday Inn & Suites Sioux Falls - Airport by IHG
Exterior
Staybridge Suites Sioux Falls by IHG
Staybridge Suites Sioux Falls by IHG
3.0 star property
9.2 out of 10, Wonderful, (1002)
"Very nice hotel! "
United States
Sally
The price is HK$855
HK$953 total
includes taxes & fees
2 Nov - 3 Nov
Staybridge Suites Sioux Falls by IHG
Exterior
Candlewood Suites Sioux Falls by IHG
Candlewood Suites Sioux Falls by IHG
2.5 star property
9.2 out of 10, Wonderful, (664)
"awesome place, Clean friendly and very nice. "
United States
Beau
The price is HK$808
HK$902 total
includes taxes & fees
24 Nov - 25 Nov
Candlewood Suites Sioux Falls by IHG
Exterior
La Quinta Inn & Suites by Wyndham Sioux Falls
La Quinta Inn & Suites by Wyndham Sioux Falls
3.0 star property
9.2 out of 10, Wonderful, (1545)
"Great place, clean , good food,"
United States
Joanne
The price is HK$659
HK$739 total
includes taxes & fees
16 Nov - 17 Nov
La Quinta Inn & Suites by Wyndham Sioux Falls
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Sioux Empire Medical Museum Hotel Reviews

Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr

Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr

10/10 Excellent
"I did not try the tub or pool I got in late and just needed a place to sleep for the night. Dara at the front desk was helpful and quick the room was clean and comfortable. Of course there was some wear in the elevator and hall but it was clean is what mattered most to me. It was also just minutes from the airport."
Timothy 1-night trip
Posted 2 days ago
Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr

Hotels near other Sioux Empire Medical Museum attractions

Great Plains Zoo

4.3/5 (74 reviews)
Why not meet the animals who live at Great Plains Zoo during your holiday in Sioux Falls? Attend a sporting event or discover the area's beautiful waterfalls.
See properties

University of Sioux Falls

4.1/5 (170 reviews)
Explore the campus of University of Sioux Falls during your trip to Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls.
See properties

Frequently asked questions

What's the area like around Sioux Empire Medical Museum?
Sioux Empire Medical Museum is located in a welcoming area of Sioux Falls known for its beautiful waterfalls and sporting events. If you're looking for a convenient place to stay, take a look at the 106 hotels and other accommodation options you'll find within a mile.
What's the best place to stay close to Sioux Empire Medical Museum?
Adjacent to Sioux Empire Medical Museum, Valley Inn is one of the top choices for your stay based on our traveller data, and this hotel offers free parking and free WiFi. Another good choice is Home2 Suites By Hilton Sioux Falls/Sanford Medical Center, located just 0.1 mi (0.2 km) away.
How many hotels are there close to Sioux Empire Medical Museum?
Expedia has 106 hotels and other accommodation options within a mile from Sioux Empire Medical Museum.
If I need to cancel the hotel reservation for my stay near Sioux Empire Medical Museum, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then use the "fully refundable" filter to view the best options available near Sioux Empire Medical Museum.
What can I see and do near Sioux Empire Medical Museum?
Washington Pavilion of Arts and Science, Center for Western Studies and The Outdoor Campus feature a variety of fascinating exhibits to see while you're in town. Learn about local history at St. Joseph Cathedral and Pettigrew Home and Museum. You can wander around Falls Park, Sherman Park or Veterans' Memorial Park if you want a dose of fresh air.

Explore a world of travel with Expedia