A large brick building with multiple windows and a tower, surrounded by trees and a grassy area.

Best Western Southeast Ohio hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
8 Oct - 9 Oct
Tomorrow
9 Oct - 10 Oct
This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

Our top choices for Southeast Ohio Best Western

A modern bathroom with a flat-screen TV, a built-in microwave, a large bathtub, and a tiled floor.
A modern restaurant with a long counter, a coffee machine, and multiple tables and chairs.
A building entrance with a brick facade, American flag, blue lights, a wheelchair parking sign, and outdoor seating.
A hotel room with a bed, two armchairs, a desk with a computer, a TV, a hot tub, and a wooden door.

1. Best Western Adena Inn

Best Western Adena Inn
Chillicothe
United States
Michelle
HK$740
HK$847 total
includes taxes & fees
1 Nov - 2 Nov
Best Western Adena Inn
A hotel room with a large bed, a desk with a computer, a TV, a bathroom with a bathtub, and a patterned carpet.
A restaurant with wooden tables and chairs, a kitchen area, and a coffee machine.
A lobby with a seating area, a coffee station, and large windows with a view of the parking lot.
A brick building with a sign reading "Best Western" at night.

2. Best Western Canal Winchester Inn - Columbus South East

Best Western Canal Winchester Inn - Columbus South East
Canal Winchester
United States
Zoe
HK$773
HK$913 total
includes taxes & fees
6 Nov - 7 Nov
Best Western Canal Winchester Inn - Columbus South East
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Top Southeast Ohio Hotel Reviews

Wingate by Wyndham St. Clairsville/Wheeling

Wingate by Wyndham St. Clairsville/Wheeling

10/10 Excellent
"Clean spacious room and bathroom. Comfy bed and pillows. Quiet area breakfast is great, eggs hash browns, sausage, waffles, and cereals. Coffee all day and night. Friendly and helpful front desk. Idk of something I personally don't like here."
CARLOS 1-night trip
Posted 3 hours ago
Wingate by Wyndham St. Clairsville/Wheeling
Christopher Inn and Suites

Christopher Inn and Suites

10/10 Excellent
"The room was clean and had everything we needed for our overnight stay, including a king sized bed that felt like a cloud (I slept like a log it was so comfortable!) The staff was very friendly and helpful. This will most likely be where we stay during future visits to Chillicothe!"
Kimberly 1-night trip
Posted 4 hours ago
Christopher Inn and Suites
Microtel Inn & Suites by Wyndham Cambridge

Microtel Inn & Suites by Wyndham Cambridge

8/10 Good
"Pretty much as expected for the price. We had an issue with the room and the front desk guy quickly assisted and moved us without issue. Breakfast was the standard for a hotel."
Adam 1-night trip
Posted 7 hours ago
Microtel Inn & Suites by Wyndham Cambridge
Ohio University Inn & Conference Center

Ohio University Inn & Conference Center

10/10 Excellent
"Very cute hotel. Would love to stay in warmer months."
cathy 1-night trip
Posted 9 hours ago
Ohio University Inn & Conference Center
The Mulberry

The Mulberry

10/10 Excellent
"This is a new facility. Contactless check-in."
Timothy 1-night trip
Posted 10 hours ago
The Mulberry
Cherry Valley Hotel

Cherry Valley Hotel

8/10 Good
"The property is unique and lent a lot to the quaintness. I choose this property because it was not sterile and boxy like traditional hotels. It was a good value. Although the mattresses need replaced, very saggy, I would stay there again."
Mark 2-night trip
Posted 10 hours ago
Cherry Valley Hotel
SureStay by Best Western Cambridge

SureStay by Best Western Cambridge

8/10 Good
"The rooms were clean and check in staff was friendly. The pool was closed which was a bummer. The breakfast was good and had a nice variety. This hotel was 1/4 the price of the Fairfield or Hampton inn at the same exit which is why we chose it. It’s not the nicest hotel we have ever stayed at but everything was good and clean!"
Ryan 1-night trip
Posted 1 day ago
SureStay by Best Western Cambridge
DogHouse Columbus

DogHouse Columbus

10/10 Excellent
"This place is a BLAST! We ended up extending our visit, abdominal so glad we did! Tilly had energy to spare and was a wealth of knowledge and even gave us a tour of the brewery. Carolyn made sure we were satisfied with our room and helped us navigate our room. Haley made sure to take awesome care of us and you could tell she had her teams back! Jose in the bar made sure we had the best service and experience. I usually don't get names when traveling, but this group took the time and effort to give us personalized attention they more than deserve the same respect! This hotel itself is great by itself with very clean rooms, interactive grounds, board games, pinball machines, outside firepits, food and drinks on site; the staff are absolutely top notch!"
Apryl 1-night trip
Posted 3 days ago
DogHouse Columbus
Hometown Inn Athens

Hometown Inn Athens

8/10 Good
"Will say a little scared at first when I arrived but relieved and comfortable once I was in my room… the location was perfect and the room was clean and cozy. Staff was always ready to assist though I never needed them. Just to take my trash. I will be back"
Maria 4-night trip
Posted 3 days ago
Hometown Inn Athens

Explore a world of travel with Expedia