A calm lake with a row of canoes on the shore and a single canoe on the water.

Best Western Southern Minnesota hotels

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Check prices for these dates

Tonight
24 Oct - 25 Oct
Tomorrow
25 Oct - 26 Oct
Next weekend
30 Oct - 1 Nov
In two weeks
6 Nov - 8 Nov

Our top choices for Southern Minnesota Best Western

An indoor swimming pool with slides, seating areas, and a covered section with umbrellas.
A restaurant setting with round tables, chairs, and empty wine glasses.
A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.
A modern kitchen with a microwave, sink, and granite countertop.

1. Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Rochester
United States
Vicky
HK$742
HK$854 total
includes taxes & fees
28 Oct - 29 Oct
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
An outdoor patio with tables, chairs, and umbrellas, surrounded by trees and a building with arches.
A reception area with a flat-screen TV, decorative vases, and coffee dispensers.
An indoor swimming pool with multiple levels, lounge chairs, and a staircase.
A hotel room with a grey sofa, a wooden coffee table, a kitchenette with a microwave, and a bathroom visible through an open door.

2. Best Western Fairmont

Best Western Fairmont
Fairmont
United States
Harlsnd
HK$1,005
HK$1,114 total
includes taxes & fees
1 Nov - 2 Nov
Best Western Fairmont
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Top Southern Minnesota Hotel Reviews

Express Suites Riverport Inn & Suites

Express Suites Riverport Inn & Suites

8/10 Good
"it’s good"
Ty 1-night trip
Posted 4 hours ago
Express Suites Riverport Inn & Suites
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

10/10 Excellent
"Convenient"
Glenn 1-night trip
Posted 17 hours ago
AmericInn by Wyndham Rochester Near Mayo Clinic
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

10/10 Excellent
"The hotel was very nice and convenient for travel to the Mayo Clinic with direct access to the underground walk way. The room was clean and nice to have the continental breakfast option. Construction was taking place outside of the hotel to improve the Mayo Clinic buildings in the area. The windows seemed to be rather low on their sound proofing ability. Almost seemed like the windows were open at times."
Angela 5-night trip
Posted 20 hours ago
Kahler Inn and Suites - Mayo Clinic Area
EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

10/10 Excellent
"Close to Mayo with hourly shuttle service. Also parking underground was secure. Good breakfast included and the bar/restaurant very nice too. We will stay here again when my husband gets his other shoulder done."
Grace 3-night trip
Posted 21 hours ago
EVEN Hotel Rochester - Mayo Clinic Area by IHG
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

10/10 Excellent
"Nice stay"
Arlan 1-night trip
Posted 21 hours ago
Hyatt House Rochester/Mayo Clinic Area
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

8/10 Good
"The staff were very friendly and helpful"
saida 2-night trip
Posted 22 hours ago
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Kahler Grand Hotel

Kahler Grand Hotel

10/10 Excellent
"My fourth hotel in the area, and one of the best. Great old hotel vibe. Hot tub and pool on the roof. Perfect location if fast Mayo appointments are on your itinerary. Two very different eating options inside the hotel. I will be Back"
Cynta 3-night trip
Posted 1 day ago
Kahler Grand Hotel
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

8/10 Good
"Parking was an additional fee but the walk wasn't bad and there was a skyway. The beds had some hair on the outer most layers, I suspect housekeeping didn't use their lint rollers on that part. Housekeeping knocked on our door and tried to enter despite us hanging the do not disturb sign and getting a late checkout with front desk, which was a bit alarming early in the morning."
Zenotha 1-night trip
Posted 1 day ago
Hotel Indigo Rochester – Mayo Clinic Area by IHG
The Plaza Hotel & Suites Winona

The Plaza Hotel & Suites Winona

8/10 Good
"Wa"
Esther 2-night trip
Posted 3 days ago
The Plaza Hotel & Suites Winona

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