Luxury Holidays in Eastern Tennessee 2026

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Carnegie Hotel & Spa

1216 W State Of Franklin Rd Johnson City TN

2 hours drive from Great Smoky Mountains National Park

Stay at this spa hotel in Johnson City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the restaurant and the helpful staff in their ...

THE TENNESSEAN Hotel

531 Henley Street Knoxville TN

55 min drive from Great Smoky Mountains National Park

Stay at this luxury hotel in Knoxville. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the clean rooms in ...

9.4/10 Exceptional! (1,002 reviews)

"I've stayed at this property several times, and every visit I am delighted. Great beds & sheets. Quiet rooms, spacious."

Reviewed on 11 Sept 2026

The Read House Hotel

107 West Martin Luther King Blvd Chattanooga TN

4 hours drive from Great Smoky Mountains National Park

Stay at this business-friendly hotel in Chattanooga. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the clean ...

9.6/10 Exceptional! (2,595 reviews)

"The Read House is a beautiful property that we always enjoy staying at. Overall,"

Reviewed on 9 Sept 2026

See all 27,403 properties in Eastern Tennessee

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.