Cape Girardeau Vacation Homes

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Our top choices for Cape Girardeau holiday homes

A living room with a TV, a fireplace, a sofa, and wall art.

1. Little Blue Cottage on Spanish

Cape Girardeau

Jeremy W.

HK$848 total

includes taxes & fees

21 Sept - 22 Sept

2. Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly

Cape Girardeau

Sara C.

HK$1,782 total

includes taxes & fees

24 Sept - 25 Sept

3. The Little Cape Lofted Cottage | Creek & Nature

Cape Girardeau

Kim K.

HK$1,821 total

includes taxes & fees

19 Sept - 20 Sept

4. The Little Château | Woodland Escape

Cape Girardeau

HK$1,629 total

includes taxes & fees

17 Sept - 18 Sept

A two-story house with a front porch, a small garden, and a white picket fence.

5. 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

Cape Girardeau

Pynktoria !.

HK$2,457 total

includes taxes & fees

17 Sept - 18 Sept

A modern kitchen with a large island, white cabinetry, and a brick accent wall.

6. Beautifully Renovated Farmhouse in Jackson, MO

Jackson

Sandy S.

HK$2,448 total

includes taxes & fees

21 Sept - 22 Sept

A house with a backyard swimming pool, outdoor furniture, and a barbecue area.

7. 4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

Cape Girardeau

Jace W.

HK$4,143 total

includes taxes & fees

21 Sept - 22 Sept

A wooden cabinet with a microwave, coffee maker, and plates.

8. Cozy and Updated Farmhouse with King Suite

Anna

Kathy H.

HK$1,239 total

includes taxes & fees

28 Sept - 29 Sept

A brick building with a sign reading "1898 Guesthouse".

9. Stunning 2 bedroom in town, close to Shawnee National Forest

Jonesboro

Dylan

HK$2,233 total

includes taxes & fees

18 Sept - 19 Sept

A covered porch with a wooden railing, a table with chairs, and a sofa.

10. Beautiful location in the secluded woods

Pomona

Candi M.

HK$1,396 total

includes taxes & fees

21 Sept - 22 Sept

A red barn with a sloped roof, surrounded by a grassy field and trees.

11. The Weber Farm - Enjoy a beautiful 100 acre farm!

Frohna

Alison C.

HK$1,322 total

includes taxes & fees

7 Oct - 8 Oct

A spacious living room with a brown leather sofa, a dining area with a wooden table and chairs, a kitchen with white cabinets and a central island, and large windows with blinds.

12. Pa’s House is an enjoyable, entirely remodeled, 2-bedroom farmhouse near Anna.

Anna

HK$2,198 total

includes taxes & fees

22 Sept - 23 Sept

A large, two-story house with a wrap-around porch, surrounded by a well-maintained garden with various flowering plants.

13. Magical Victorian near hiking / wine trail

Anna

Rachel H.

HK$2,633 total

includes taxes & fees

17 Sept - 18 Sept

A wooden deck with two white Adirondack chairs and a small round table.

14. Walk to Weddings-Wineries-Trails, Family Friendly Home in Downtown Alto Pass

Alto Pass

brian O.

HK$2,033 total

includes taxes & fees

29 Sept - 30 Sept

A bedroom with a bed, a desk, a chair, a television, and a ceiling fan.

15. Vulture's Roost

Makanda

cris g.

HK$1,228 total

includes taxes & fees

17 Sept - 18 Sept

A red barn-style building with a sign reading "Farm Market" and a stage with chairs and a table.

16. Farm Fresh Eggs, Golf Cart, Telescope

Alto Pass

Dianne M.

HK$1,835 total

includes taxes & fees

28 Sept - 29 Sept

A spacious living area with a kitchen, a dining table, and comfortable seating.

17. Whole Inn Rental! 5 King Beds, 2 Hot Tubs

Cobden

HK$5,847 total

includes taxes & fees

17 Sept - 18 Sept

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Top Cape Girardeau Hotel Reviews

Pear Tree Inn Cape Girardeau West

10/10 Excellent

"Good price, pleasant staff, clean room and facilities, filling buffet breakfast. Water for the shower could have been warmer."

Little Blue Cottage on Spanish

10/10 Excellent

"I cannot say enough about the hosts. I messed up my dates. They immediately found me a place to cover the night. I had expected to have to find a hotel but they smoothly moved us into a nearby property. It was such a relief. Both houses are perfect for our needs. Small but they had everything we needed. The Eden house was a lovely old carriage house. Beautifully done. Very comfortable. The little blue house is also small but again perfect. Both are less than a block from our new favorite Tapas bar. The location was perfect. We could get everywhere we needed to go off one of the two cross streets. The house could use some updates, but it seems like they are doing that. Everything worked. The AC did an amazing job keeping up with the extreme heat. The bed was extremely comfortable for both of us, which doesn't usually happen. One cautionary note, the extremely comfortable bed was extremely high. It took me a few tries to figure out how to get into it. If you have mobility issues you may want to ask for the other house.These hosts made our stay in Cape a lovely one. And I cannot thank them enough for going out of their way to solve a problem I created. They were wonderful and I will stay with them again anytime the need arises."

Find out more about Cape Girardeau