A red train on tracks, palm trees, and modern buildings.

Central San Diego Holiday Rentals

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Check prices for these dates

In two weeks
23 Oct - 25 Oct
In two months
4 Dec - 6 Dec
In three months
1 Jan - 3 Jan
In four months
29 Jan - 31 Jan

Our top choices for Central San Diego holiday rentals

A narrow, enclosed walkway with wooden railings and a metal grid barrier, leading to a building entrance.

1. City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.6 out of 10, Exceptional, (221 reviews)
"Friendly staff!"
United States
Donavin
The price is HK$902
HK$1,284 total
includes taxes & fees
1 Nov - 2 Nov
City24 Hotel Little Italy Mission Hills
A spacious lobby with a sofa, chairs, a bookshelf, and a large window with a view of greenery.

2. Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Uptown Inn by Vantaggio - Limited Service Apart-Hotel
2.5 star property
Hillcrest
8.4 out of 10, Very good, (483 reviews)
"We had a great stay! The room had a charming Parisian feel—compact and studio-style, but completely modern and spotlessly clean."
United States
Josh
The price is HK$734
HK$827 total
includes taxes & fees
26 Oct - 27 Oct
Uptown Inn by Vantaggio - Limited Service Apart-Hotel
A two-story house with a prominent front entrance, a balcony, and a garage.

3. San Diego Centralized Retreat

San Diego Centralized Retreat
Birdland
10.0 out of 10, Exceptional, (1 review)
"A beautiful apartment! Definitely going to reserve that location for more days next time. Kitchen is great and loved having upstairs-downstairs for separate spaces when one of us was working"
United States
Margaret C.
The price is HK$488
HK$1,479 total
includes taxes & fees
14 Oct - 15 Oct
San Diego Centralized Retreat
A bedroom with a bed, a desk, a chair, a ceiling fan, and a door leading to another room.

4. Private Entrance With Crisp Sheets And A Cozy Grotto Shower

Private Entrance With Crisp Sheets And A Cozy Grotto Shower
Mid-City
10.0 out of 10, Exceptional, (1 review)
The price is HK$494
HK$1,113 total
includes taxes & fees
14 Oct - 15 Oct
Private Entrance With Crisp Sheets And A Cozy Grotto Shower
A living room with a blue sofa, a round coffee table, and a world map on the wall.

5. Charming 2 bedroom San Diego home-Close to Downtown/Balboa Park/SeaWorld/Beaches

Charming 2 bedroom San Diego home-Close to Downtown/Balboa Park/SeaWorld/Beaches
Mid-City
8.0 out of 10, Very good, (4 reviews)
The price is HK$839
HK$3,570 total
includes taxes & fees
12 Oct - 13 Oct
Charming 2 bedroom San Diego home-Close to Downtown/Balboa Park/SeaWorld/Beaches
A hotel room with two beds, a large mirror, and decorative wall art.

6. Modern 1BR/1BA Getaway in Central San Diego – Walk to Zoo, Balboa Park & Dining

Modern 1BR/1BA Getaway in Central San Diego – Walk to Zoo, Balboa Park & Dining
University City
10.0 out of 10, Exceptional, (1 review)
"Nice spacious 1 bed room apartment in very nice area "
United States
ILL W.
The price is HK$1,413
HK$2,463 total
includes taxes & fees
25 Oct - 26 Oct
Modern 1BR/1BA Getaway in Central San Diego – Walk to Zoo, Balboa Park & Dining
A sunset over a beach with a pier in the background.

7. Adorable 1 bedroom house 8 min from La Jolla!

Adorable 1 bedroom house 8 min from La Jolla!
Bay Ho
10.0 out of 10, Exceptional, (63 reviews)
"Clean place, great location, great AC, can’t ask for more! Perfect for a couple."
United States
Justin H.
The price is HK$1,568
HK$2,566 total
includes taxes & fees
15 Oct - 16 Oct
Adorable 1 bedroom house 8 min from La Jolla!
A patio with outdoor furniture, a pathway, and a fence.

8. Cozy 2-Bedroom Cottage Near Balboa Park

Cozy 2-Bedroom Cottage Near Balboa Park
Mid-City
8.8 out of 10, Excellent, (12 reviews)
"Overall it was a great place to stay."
United States
Cristal M.
The price is HK$1,012
HK$2,358 total
includes taxes & fees
25 Oct - 26 Oct
Cozy 2-Bedroom Cottage Near Balboa Park
A modern living room with a grey sofa, a small round coffee table, and a ceiling fan.

9. Charming 1-bedroom house in Beautiful San Diego with WiFi, AC

Charming 1-bedroom house in Beautiful San Diego with WiFi, AC
Mid-City
10.0 out of 10, Exceptional, (2 reviews)
"Our stay was excellent. We enjoyed the space. Used TV, sofa and bed… nothing else. Quiet and easy access to property. "
United States
Socorro C.
The price is HK$1,099
HK$2,367 total
includes taxes & fees
12 Oct - 13 Oct
Charming 1-bedroom house in Beautiful San Diego with WiFi, AC
A modern kitchen with white cabinetry, a built-in microwave, a dishwasher, and a stainless steel refrigerator.

10. Luxury San Diego 1BR with Premium Conveniences

Luxury San Diego 1BR with Premium Conveniences
Mid-City
The price is HK$918
HK$2,236 total
includes taxes & fees
1 Nov - 2 Nov
Luxury San Diego 1BR with Premium Conveniences
A modern living room with a green sofa, a white coffee table, a flat-screen TV mounted on the wall, and a small table with a lamp and a plant.

11. Casa Carlos - In the heart of San Diego

Casa Carlos - In the heart of San Diego
Mid-City
9.0 out of 10, Wonderful, (7 reviews)
"Easy parking and lots of privacy. The bungalow was clean and host was very prompt with communication. I’d stay again. "
United States
Johanna G.
Casa Carlos - In the heart of San Diego
A balcony with a fire feature, a grill, and a view of a cityscape at sunset.

12. Close to Airport | Walk to Restaurants

Close to Airport | Walk to Restaurants
Middletown
8.8 out of 10, Excellent, (3 reviews)
"Exactly as advertised. Door to bathroom being shutters was an interesting decision but apart from that it was clean and in good condition and generally a good place to stay. Great location, close to a row of restaurants and can see the taxiways for San Diego international."
United States
Yan W.
The price is HK$644
HK$2,553 total
includes taxes & fees
14 Oct - 15 Oct
Close to Airport | Walk to Restaurants
A beachside hotel with multiple floors, a sandy beach in the foreground, and palm trees lining the shore.

13. Secluded, Charming and Unique! Spacious Apartment EXCELLENT Central Location

Secluded, Charming and Unique! Spacious Apartment EXCELLENT Central Location
Mission Valley
9.0 out of 10, Wonderful, (67 reviews)
"It was okay"
United States
Nicole
The price is HK$1,165
HK$2,875 total
includes taxes & fees
16 Oct - 17 Oct
Secluded, Charming and Unique! Spacious Apartment EXCELLENT Central Location
A residential property with a gated entrance, a pergola, and a wooden fence.

14. 1BR King Bed Apartment with AC in sunny San Diego

1BR King Bed Apartment with AC in sunny San Diego
Mid-City
The price is HK$742
HK$2,094 total
includes taxes & fees
27 Oct - 28 Oct
1BR King Bed Apartment with AC in sunny San Diego
A rustic interior with wooden walls, a long row of wooden paddles, and metal barrels.

15. Private Cozy Clean, close to EVERYTHING

Private Cozy Clean, close to EVERYTHING
Mid-City
9.8 out of 10, Exceptional, (73 reviews)
The price is HK$1,068
HK$2,853 total
includes taxes & fees
3 Nov - 4 Nov
Private Cozy Clean, close to EVERYTHING
A living room with a green sofa, a coffee table, and a dining area with a table and chairs. There are plants and framed pictures on the walls.

16. Colorful & Cozy Oasis: Walk Score 95/100, Free Pkg

Colorful & Cozy Oasis: Walk Score 95/100, Free Pkg
North Park
9.6 out of 10, Exceptional, (9 reviews)
"Very kind host and great walkable location. The yard made it very convenient for my dog and the bed was super comfy"
United States
Rae-Matthew E.
The price is HK$839
HK$2,526 total
includes taxes & fees
12 Oct - 13 Oct
Colorful & Cozy Oasis: Walk Score 95/100, Free Pkg
A building with a covered outdoor seating area, surrounded by various plants and a large rock.

17. Adorable 1 bd cottage, heart of Old Town-- WE LOVE PETS! Insta @oldtownvacay

Adorable 1 bd cottage, heart of Old Town-- WE LOVE PETS! Insta @oldtownvacay
Old Town San Diego
10.0 out of 10, Exceptional, (305 reviews)
"Super cute, private little cottage in a great location. Loved the stay, very easy process and great host!"
United States
Ross
The price is HK$1,236
HK$1,574 total
includes taxes & fees
12 Oct - 13 Oct
Adorable 1 bd cottage, heart of Old Town-- WE LOVE PETS! Insta @oldtownvacay
Drift off in ultra-comfy linens and a memory foam mattress where restful nights come easy.

18. The Great Escape 1| Free Beach Gear | Hot Tub, Harbor Views & Fire Pit

The Great Escape 1| Free Beach Gear | Hot Tub, Harbor Views & Fire Pit
Middletown
8.4 out of 10, Very good, (5 reviews)
"Perfect amount of space for 3 people, no issues in the house, everything worked fine. You can hear everything that happens upstairs but that's kind of expected when staying on the bottom level of anything. Hosts were very helpful, let us check in early which was convenient for us! Close to airport and downtown which was nice. Overall great stay!"
United States
Gabby W.
The price is HK$1,070
HK$3,060 total
includes taxes & fees
27 Oct - 28 Oct
The Great Escape 1| Free Beach Gear | Hot Tub, Harbor Views & Fire Pit
A bedroom with a bed, a TV, a ceiling fan, and a view of a living room with a blue sofa.

19. Stylish & Comfy Gem: Walk To Everything ~ Parking!

Stylish & Comfy Gem: Walk To Everything ~ Parking!
North Park
9.4 out of 10, Exceptional, (3 reviews)
"Absolutely wonderful first experience with Vrbo. Rebecca was always available & is definitely a top notch host!Lovely home & hope to be back on San Diego soon &!would definitely recommend those property to everyone."
United States
Martha M.
The price is HK$898
HK$2,593 total
includes taxes & fees
15 Oct - 16 Oct
Stylish & Comfy Gem: Walk To Everything ~ Parking!
A wooden gate with a wooden archway above it, surrounded by lush greenery and flowering plants.

20. 2 bd w/ yard in heart of Old Town-- WE LOVE PETS! Check our Insta @oldtownvacay

2 bd w/ yard in heart of Old Town-- WE LOVE PETS! Check our Insta @oldtownvacay
Old Town San Diego
10.0 out of 10, Exceptional, (229 reviews)
"We enjoyed our stay and would recommend staying here."
United States
Robin D.
The price is HK$1,413
HK$1,797 total
includes taxes & fees
19 Oct - 20 Oct
2 bd w/ yard in heart of Old Town-- WE LOVE PETS! Check our Insta @oldtownvacay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Central San Diego Hotel Reviews

California Suites Hotel

California Suites Hotel

10/10 Excellent
"It was nice and clean. There is a kitchen in the room to use."
Stephanie 1-night trip
Posted 2 hours ago
California Suites Hotel

Find out more about Central San Diego

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