Best Charleston Hotels in 2026 from HK$450 - Fully Refundable Options

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Our top choices for Charleston hotels

A building with a fountain and flower beds in front.

A hotel room with a beige sofa, two patterned armchairs, a ceiling fan, a flat-screen TV, and a window with curtains.

A reception area with a stone wall, wooden cabinets, and a sign for The Riverstone Hotel.

A modern kitchen with dark wooden cabinets, a central island, and a ceiling fan.

1. The Riverstone Hotel Charleston-Sikeston

Charleston

Jay

HK$521

HK$579 total

includes taxes & fees

26 Sept - 27 Sept

A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.

A reception area with a counter, a flat-screen TV, and a window with blinds.

A restaurant with wooden cabinets, a refrigerator, and a counter with various items. There are tables and chairs for dining.

A reception area with a sofa, a coffee table, a potted plant, and a framed picture on the wall.

2. Super 8 by Wyndham Charleston/Sikeston East MO

Charleston

William

HK$467

HK$518 total

includes taxes & fees

27 Sept - 28 Sept

A hotel room with a large bed, a desk, a television, and a bathroom visible through an open door.

A bathroom with a sink, mirror, towel rack, shower, and toilet.

A motel with a sign reading "Eagle Inn" and a parking lot with several cars.

A kitchen with wooden cabinets, a granite countertop, a built-in microwave, and a window with a view.

3. Eagle Inn Charleston

Charleston

Jackson

HK$604

HK$670 total

includes taxes & fees

25 Sept - 26 Sept

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

An outdoor seating area with sofas and planters, surrounded by a building with large windows and a brick wall.

A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.

A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.

4. Drury Inn & Suites Sikeston, MO

Sikeston

Scott

HK$839

HK$965 total

includes taxes & fees

29 Sept - 30 Sept

A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.

A reception area with a wooden reception desk, a large painting on the wall, and a potted plant.

An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows providing natural light.

A hotel with a covered entrance, a sign indicating a restaurant, and a well-lit parking area.

5. Best Western Plus Sikeston I-55

Sikeston

Shelley

HK$684

HK$779 total

includes taxes & fees

27 Sept - 28 Sept

A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.

A kitchenette with a coffee machine, a kettle, and storage shelves.

A reception area with a reception desk, a large wall-mounted sign, and a potted plant.

An indoor swimming pool with a tiled floor, a lifeguard chair, and a pool ladder.

6. Holiday Inn Express & Suites Sikeston Southwest by IHG

Sikeston

michael

HK$745

HK$844 total

includes taxes & fees

25 Oct - 26 Oct

A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.

A hotel lobby with a bar area, seating arrangements, and a large window providing natural light.

A Hampton Inn hotel with a modern facade, a stone entrance, and a well-lit entrance area.

An indoor swimming pool with lounge chairs, a lifeguard stand, and large windows offering a view of the outside.

7. Hampton Inn Sikeston

Sikeston

John

HK$797

HK$903 total

includes taxes & fees

11 Oct - 12 Oct

A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.

A spacious room with a large dining table and chairs, a kitchenette area, and a television mounted on the wall.

A Days Inn hotel with a brick facade, large windows, and a sign above the entrance.

8. Days Inn and Suites by Wyndham Sikeston

Sikeston

David

HK$520

HK$593 total

includes taxes & fees

27 Sept - 28 Sept

An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.

An outdoor bar area with a modern design, featuring a counter, seating, and a view of the interior.

A modern indoor swimming pool with clear glass walls, a tiled deck, and multiple lounge chairs.

A modern hotel building with a sign reading "TOWNPLACE SUITES BY MARRIOTT" and "Fairfield BY MARRIOTT".

9. Fairfield Inn & Suites by Marriott Sikeston

Sikeston

Allen

HK$792

HK$897 total

includes taxes & fees

4 Oct - 5 Oct

A hotel lobby with a reception desk, seating area, and a large window.

A hotel lobby with a reception desk, two armchairs, a coffee table, and large windows with potted plants.

A hotel room with a desk, chair, television, and a lamp.

A Quality Inn hotel with a green sign, a covered outdoor area, and a parking lot.

10. Quality Inn Cairo I-57

Cairo

Santiago

HK$556

HK$617 total

includes taxes & fees

23 Oct - 24 Oct

A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.

A hotel room with a flat-screen TV, a microwave, a coffee maker, a dining table, and two sofas.

A hotel kitchen with a long counter, various appliances, and a tiled backsplash.

A motel with a covered entrance, multiple rooms, and a parking lot.

11. Super 8 by Wyndham Sikeston/Miner Area

Sikeston

William

HK$448

HK$511 total

includes taxes & fees

4 Oct - 5 Oct

A modern hotel with a sign reading "Towneplace Suites by Marriott Fairfield." It features a flat roof, large windows, and a well-lit entrance.

A modern hotel room with a large window, a gray sofa, a small round table, a white chair, and a bed.

A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.

12. TownePlace Suites by Marriott Sikeston

Sikeston

Stacy

HK$784

HK$888 total

includes taxes & fees

4 Oct - 5 Oct

A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.

A Travel Inn and Suites building with a prominent illuminated sign, a brick facade, and a parking lot.

A modern kitchen with stainless steel appliances, wooden cabinets, and a bright yellow accent wall.

A reception area with a sign for 'Travel Inn and Suites' and a counter with a computer and a phone.

13. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Sikeston

Sharika West

HK$545

HK$621 total

includes taxes & fees

27 Sept - 28 Sept

A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.

A hotel room with a bed, a desk with a TV, a chair, a bathroom with a bathtub, and a window with curtains.

A hotel lobby with a reception desk, seating area, and large windows offering a view of the outdoors.

A hot tub area with a tiled floor, a wooden deck surrounding the tub, and a view of the sky through large windows.

14. Comfort Inn & Suites Sikeston I-55

Sikeston

Starlette

HK$701

HK$799 total

includes taxes & fees

20 Oct - 21 Oct

A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a painting on the wall.

A motel with a red roof and beige walls, a parking lot, and a signboard.

A bathroom with yellow walls, a wooden cabinet, a sink, a mirror, and a hanging towel rack.

A reception desk with a computer, a framed picture on the wall, and a vase with flowers.

15. La Center Motel

La Center

Carrie

HK$381

HK$450 total

includes taxes & fees

25 Sept - 26 Sept

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.

An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.

A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.

16. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Cape Girardeau

ELAINE

HK$792

HK$902 total

includes taxes & fees

4 Oct - 5 Oct

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.

17. Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

Sandra

HK$784

HK$885 total

includes taxes & fees

28 Sept - 29 Sept

A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.

A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.

A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.

A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.

18. Drury Inn & Suites Cape Girardeau

Cape Girardeau

Teresa

HK$706

HK$796 total

includes taxes & fees

9 Oct - 10 Oct

A hotel room with two beds, a desk, a chair, a TV, and a mirror.

A reception area with a sofa, a small table, a trash bin, a microwave, and a book display.

A motel with a blue awning and a green 7-Eleven. It has a covered parking area and a two-story structure with a balcony.

A reception area with a counter, a coffee machine, and seating.

19. Country Yard Inn and Suite

Sikeston

William

HK$481

HK$572 total

includes taxes & fees

27 Sept - 28 Sept

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.

A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.

A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.

20. Pear Tree Inn Cape Girardeau West

Cape Girardeau

Raidas

HK$565

HK$637 total

includes taxes & fees

28 Sept - 29 Sept

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Top Charleston Hotel Reviews

Drury Inn & Suites Sikeston, MO

10/10 Excellent

"Clean room and perfect stay. We have come to consistently appreciate Drury brand for a quality stay. We would definitely recommend this location for clean comfortable accommodations."

Super 8 by Wyndham Sikeston/Miner Area

10/10 Excellent

"The hall ways smelled so good but we did get dirty blankets . They have many restaurants and stores options really closed by so if you have children it is a great spot to stop specifically since is just in the entry or exit of the hwy ."

Hampton Inn Sikeston

10/10 Excellent

"Staff was great"

Courtyard by Marriott Cape Girardeau Downtown

10/10 Excellent

"Hotels.com said there is a rooftop garden. When I asked where it was, they said they don’t have one. There is a rooftop bar next door. Other than that everything was gorgeous!"

Drury Inn & Suites Cape Girardeau

10/10 Excellent

"Great hotel, had zero issues and staff was lovely"

Super 8 by Wyndham Charleston/Sikeston East MO

10/10 Excellent

"Súper affordable pricing, and the property was clean and comfortable! Complimentary breakfast was a plus!"

Days Inn and Suites by Wyndham Sikeston

10/10 Excellent

"This was a very good value. It has been the best hotel I've stayed at in awhile."

Pear Tree Inn Cape Girardeau West

8/10 Good

"I was looking for something that was good quality and wouldn’t break my wallet. This place was what I was expecting. Lady working the breakfast was extremely polite and helpful."

The Riverstone Hotel Charleston-Sikeston

8/10 Good

"Overall it was excellant, other then the toilet running constantly... Pool could have been cleaner, considering the heat-wave they were having............."