New Madrid hotels from HK$382

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24 Dec - 25 Dec
Tomorrow
25 Dec - 26 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

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Our top choices for New Madrid hotels

Exterior
Super 8 By Wyndham Marston

Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
2.0 star property
Marston
7.8 out of 10, Good, (39)
This hotel in Marston offers complimentary perks including daily full breakfast served between 6:00 AM and 9:00 AM, WiFi, and self parking. Conveniently located for travellers exploring the area.
"Great hotel, great staff"
United States
Dmitry
The price is HK$448
HK$512 total
includes taxes & fees
27 Dec - 28 Dec
Super 8 By Wyndham Marston
Gazebo
Travel Inn

Travel Inn

Travel Inn
2.5 star property
Marston
6.0 out of 10, (116)
This welcoming Marston hotel offers complimentary on-the-go breakfast to start your day right. Take advantage of free WiFi to stay connected and enjoy the convenience of complimentary self parking during your countryside stay.
"Had a great time loved it "
United States
Shyianne
The price is HK$334
HK$382 total
includes taxes & fees
25 Dec - 26 Dec
Travel Inn
Bar (on property)
Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
2.5 star property
Sikeston
9.2 out of 10, Wonderful, (41)
This business-friendly hotel offers an indoor pool, restaurant, and complimentary breakfast. Located near Sikeston Depot Museum, guests enjoy free WiFi and parking while exploring local attractions.
"THE ROOM WAS SPOTLESS, CLEAN LOBBY, WARM AND LOT OF VARITY BREAKFAST, STAFF IS SO NICE."
United States
AHMAD
The price is HK$786
HK$889 total
includes taxes & fees
1 Jan - 2 Jan 2026
Fairfield Inn & Suites by Marriott Sikeston
Exterior
Hampton Inn Sikeston

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (450)
Take a refreshing dip in the indoor pool or maintain your routine at the fitness centre. Free breakfast, WiFi, and parking enhance your stay. Central Park and Sikeston Depot Museum are just moments away from this welcoming retreat.
"clean room, comfy bedding, nice staff, convenient location "
United States
Alexa
The price is HK$759
HK$859 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn Sikeston
Bar (on property)
TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.2 out of 10, Wonderful, (9)
Set near Central Park and Sikeston Depot Museum, this business-friendly hotel offers a refreshing indoor pool and convenient daily breakfast. Enjoy well-appointed accommodation with complimentary WiFi and self parking just 32 minutes from Cairo Regional Airport.
"Great hotel! Very clean, quiet, plenty of amenities, pool was clean, breakfast in the morning was good with lots of options. I would definitely stay here again. "
United States
Scott
The price is HK$918
HK$1,039 total
includes taxes & fees
1 Jan - 2 Jan 2026
TownePlace Suites by Marriott Sikeston
Exterior
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (443)
Discover comfort at this Sikeston hotel with an indoor pool and fitness centre. Enjoy complimentary breakfast, WiFi, and parking while exploring nearby Central Park and Sikeston Depot Museum. Guests consistently praise the helpful staff and immaculate rooms.
"Staff was great. Hotel was clean. Great sleep. "
United States
Jeffrey
The price is HK$817
HK$925 total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express & Suites Sikeston Southwest by IHG
Blackout curtains, iron/ironing board, free WiFi, bed sheets
Reelfoot Lake Inn

Reelfoot Lake Inn

Reelfoot Lake Inn
2.0 star property
Tiptonville
7.2 out of 10, Good, (461)
"Bed bugs in two separate rooms, wouldn’t refund my room"
United States
Jacquelynn
The price is HK$542
HK$622 total
includes taxes & fees
25 Dec - 26 Dec
Reelfoot Lake Inn
Desk, free WiFi, bed sheets
New Orleans Inn Portageville

New Orleans Inn Portageville

New Orleans Inn Portageville
2.5 star property
Portageville
8.0 out of 10, Very good, (732)
This welcoming motel offers clean rooms praised by guests, plus convenient amenities including free WiFi and parking. The 24-hour front desk ensures assistance anytime during your stay in charming Portageville.
"Friendly sta"
United States
Melissa
New Orleans Inn Portageville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular New Madrid attractions

New Madrid Historical Museum

4.1/5 (17 reviews)
Explore the powerful 1811-1812 earthquakes that reshaped America's heartland at this historic museum. Engage with knowledgeable curators while viewing artefacts from Native American cultures and the Civil War.
See properties

River Ridge Winery

3.9/5 (10 reviews)
Sip handcrafted wines in a century-old farmhouse atop the Mississippi River hills. Wander through estate vineyards or enjoy fresh meals on the scenic grounds of this Missouri wine destination.
See properties

Learn more about New Madrid

The New Madrid Historical Museum reveals the dramatic storey of the 1811-1812 earthquakes that changed the course of the Mississippi River. Enjoy peaceful fishing at Donaldson Point Conservation Area or take a sunset river cruise to spot bald eagles along the mighty Mississippi.

See all hotels in New Madrid
Mississippi River Walk at New Madrid. A magnificent view of the Mississippi river from atop of the levee. A steamboat is docked down river. .

Top New Madrid Hotel Reviews

New Orleans Inn Portageville

New Orleans Inn Portageville

10/10 Excellent
"Friendly sta"
Melissa 2-night trip
Posted 4 days ago
New Orleans Inn Portageville

More cheap stays in New Madrid

Super 8 By Wyndham Marston

Super 8 By Wyndham Marston

501 S Outer Road Marston MO
The price is HK$448 per night from 27 Dec to 28 Dec
HK$448
HK$512 total
27 Dec - 28 Dec
includes taxes & fees
7.8/10 Good! (39 reviews)

Frequently asked questions

Where is the best place for a stay in New Madrid?
Hampton Inn Sikeston, located 19 mi (30.5 km) from the heart of New Madrid, is a top choice for your stay, based on our traveller data. Two other choices for your stay in the area are Fairfield Inn & Suites by Marriott Sikeston and For Larger Groups Up To 24, Right on Reelfoot Lake--Private Dock And Pier.. See all available top hotels, or vacation rentals in New Madrid.
What are some of the best holiday rentals that New Madrid has to offer?
Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!: This highly rated holiday home rental in New Madrid offers a garden, a selection of games and air conditioning to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge and a stovetop. See all vacation rentals in New Madrid.
If I need to cancel my hotel reservation in New Madrid, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in New Madrid.
What is staying in New Madrid like?
Visitors can enjoy all that New Madrid has to offer, including the parks and museums. There are 54 hotels and other accommodation options in the surrounding area. Find out more about New Madrid.
What should I do while I'm visiting New Madrid?
Cultural venues include New Madrid Historical Museum and Hunter-Dawson State Historic Site. A couple of additional sights to add to your itinerary are River Ridge Winery and Mississippi River. Take a look at what more there is to see and do in Expedia's New Madrid guide.
What's the seasonal weather in New Madrid?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 6°C. Average annual precipitation for New Madrid is 1537 mm.

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