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Cherokee Seneca hotels in Louisville

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27 Dec - 28 Dec
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2 Jan - 4 Jan
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9 Jan - 11 Jan

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Our top choices for Cherokee Seneca hotels

Breakfast, lunch and dinner served
Hyatt Regency Louisville

Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
Downtown Louisville, 6.4 km from Cherokee Seneca
8.8 out of 10, Excellent, (1001)
"Enjoyed our stay "
United States
Jedediah
The price is HK$987
HK$1,161 total
includes taxes & fees
29 Dec - 30 Dec
Hyatt Regency Louisville
4 restaurants, breakfast, lunch, dinner served; American cuisine
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville, 6.5 km from Cherokee Seneca
9.0 out of 10, Wonderful, (3899)
"Great place to stay! "
United States
Rochelle
The price is HK$1,036
HK$1,219 total
includes taxes & fees
5 Jan - 6 Jan 2026
Galt House Hotel Trademark Collection by Wyndham
Free daily buffet breakfast
SpringHill Suites by Marriott Louisville Downtown

SpringHill Suites by Marriott Louisville Downtown

SpringHill Suites by Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 5.9 km from Cherokee Seneca
8.4 out of 10, Very good, (1003)
"The staff was great and the hotel was really nice. Great place to stay."
United States
James
The price is HK$723
HK$850 total
includes taxes & fees
30 Dec - 31 Dec
SpringHill Suites by Marriott Louisville Downtown
Dining
Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
Downtown Louisville, 5.8 km from Cherokee Seneca
9.4 out of 10, Exceptional, (1001)
"The staff and lobby were top tier!"
United States
Emily
The price is HK$740
HK$870 total
includes taxes & fees
18 Jan - 19 Jan 2026
Cambria Hotel Louisville Downtown-Whiskey Row
View from room
Aloft Louisville Downtown

Aloft Louisville Downtown

Aloft Louisville Downtown
3.0 star property
Downtown Louisville, 6.1 km from Cherokee Seneca
9.0 out of 10, Wonderful, (1000)
"Great room and location."
Canada
Rene
The price is HK$810
HK$953 total
includes taxes & fees
11 Jan - 12 Jan 2026
Aloft Louisville Downtown
Exterior
Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
Downtown Louisville, 7.1 km from Cherokee Seneca
8.8 out of 10, Excellent, (1669)
"very clean throughout, helpful staff,very nice breakfast"
United States
Wayne
The price is HK$637
HK$750 total
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Express & Suites Louisville Downtown by IHG
Front of property
21c Museum Hotel Louisville

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville, 7 km from Cherokee Seneca
9.2 out of 10, Wonderful, (1002)
"Staff was very kind, the art was fantastic, location was perfect to explore Whiskey Row, and we had a gorgeous room. Loved our time away there!"
United States
Tammy
The price is HK$1,080
HK$1,310 total
includes taxes & fees
1 Jan - 2 Jan 2026
21c Museum Hotel Louisville
Premium bedding, in-room safe, desk, laptop workspace
Derby City Gaming & Hotel - A Churchill Downs Property

Derby City Gaming & Hotel - A Churchill Downs Property

Derby City Gaming & Hotel - A Churchill Downs Property
4.0 star property
6 km from Cherokee Seneca
9.4 out of 10, Exceptional, (1721)
"Great place to stay"
United States
april
Derby City Gaming & Hotel - A Churchill Downs Property
Terrace/patio
Hyatt House Louisville East

Hyatt House Louisville East

Hyatt House Louisville East
2.0 star property
9.2 km from Cherokee Seneca
9.6 out of 10, Exceptional, (1003)
"The hotel was very clean and the decor is appealing."
United States
Erika L
The price is HK$847
HK$997 total
includes taxes & fees
29 Dec - 30 Dec
Hyatt House Louisville East
Dinner served
Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville, 6.4 km from Cherokee Seneca
9.0 out of 10, Wonderful, (1125)
"Staff was courteous, hotel was beautiful and clean, and breakfast was amazing!"
United States
Shunskis
The price is HK$950
HK$1,117 total
includes taxes & fees
11 Jan - 12 Jan 2026
Embassy Suites Louisville Downtown
Exterior
Fairfield Inn & Suites by Marriott Louisville Shepherdsville

Fairfield Inn & Suites by Marriott Louisville Shepherdsville

Fairfield Inn & Suites by Marriott Louisville Shepherdsville
2.5 star property
19.2 km from Cherokee Seneca
9.4 out of 10, Exceptional, (410)
"Breakfast was good"
United States
Chantal
The price is HK$785
HK$874 total
includes taxes & fees
1 Jan - 2 Jan 2026
Fairfield Inn & Suites by Marriott Louisville Shepherdsville
Snack bar
Tru by Hilton Shepherdsville Louisville South

Tru by Hilton Shepherdsville Louisville South

Tru by Hilton Shepherdsville Louisville South
2.5 star property
19.1 km from Cherokee Seneca
9.2 out of 10, Wonderful, (842)
"Excellent service from check in to check out highly recommend very clean "
United States
Rebecca
The price is HK$668
HK$743 total
includes taxes & fees
11 Jan - 12 Jan 2026
Tru by Hilton Shepherdsville Louisville South
Exterior
Marriott Louisville East

Marriott Louisville East

Marriott Louisville East
4.0 star property
Jeffersontown, 9.9 km from Cherokee Seneca
9.0 out of 10, Wonderful, (1002)
"Great stay"
United States
Brad
The price is HK$852
HK$1,003 total
includes taxes & fees
1 Jan - 2 Jan 2026
Marriott Louisville East
Lobby
Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 7.1 km from Cherokee Seneca
9.2 out of 10, Wonderful, (517)
"Accommodations were perfect. Staff excellent. Food was very good."
United States
Bennett
The price is HK$754
HK$887 total
includes taxes & fees
12 Jan - 13 Jan 2026
Towneplace Suites By Marriott Louisville Downtown
Exterior
Courtyard by Marriott Louisville Airport

Courtyard by Marriott Louisville Airport

Courtyard by Marriott Louisville Airport
3.0 star property
7.1 km from Cherokee Seneca
9.0 out of 10, Wonderful, (344)
"Amenities, restaurants, location, room was nice "
United States
Anitra
The price is HK$762
HK$896 total
includes taxes & fees
30 Dec - 31 Dec
Courtyard by Marriott Louisville Airport
Lobby
Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
Downtown Louisville, 6.4 km from Cherokee Seneca
8.6 out of 10, Excellent, (1003)
"Excellent location and a great lobby bar with a top notch bourbon selection. "
United States
vincent
The price is HK$1,132
HK$1,332 total
includes taxes & fees
30 Dec - 31 Dec
Seelbach Hilton Louisville Downtown
Exterior
Fairfield Inn & Suites by Marriott Louisville Downtown

Fairfield Inn & Suites by Marriott Louisville Downtown

Fairfield Inn & Suites by Marriott Louisville Downtown
2.5 star property
Downtown Louisville, 6 km from Cherokee Seneca
8.2 out of 10, Very good, (1004)
"Friendly staff, clean room, breakfast was good"
United States
steven
The price is HK$653
HK$768 total
includes taxes & fees
30 Dec - 31 Dec
Fairfield Inn & Suites by Marriott Louisville Downtown
Exterior
Holiday Inn Express Hotel & Suites Louisville East by IHG

Holiday Inn Express Hotel & Suites Louisville East by IHG

Holiday Inn Express Hotel & Suites Louisville East by IHG
2.5 star property
Jeffersontown, 13.1 km from Cherokee Seneca
9.2 out of 10, Wonderful, (758)
"Very good breakfast and friendly staff. The room very spacious and very clean"
United States
Khanh
The price is HK$645
HK$759 total
includes taxes & fees
2 Jan - 3 Jan 2026
Holiday Inn Express Hotel & Suites Louisville East by IHG
Free daily on-the-go breakfast
Hampton Inn Simpsonville

Hampton Inn Simpsonville

Hampton Inn Simpsonville
2.5 star property
29.6 km from Cherokee Seneca
9.4 out of 10, Exceptional, (906)
"Would stay again"
United States
Chris
The price is HK$695
HK$773 total
includes taxes & fees
3 Jan - 4 Jan 2026
Hampton Inn Simpsonville
Exterior
Comfort Suites Louisville Airport

Comfort Suites Louisville Airport

Comfort Suites Louisville Airport
2.5 star property
9.5 km from Cherokee Seneca
8.2 out of 10, Very good, (864)
"The room was clean, front desk people were so polite! "
United States
Sara
The price is HK$729
HK$858 total
includes taxes & fees
30 Dec - 31 Dec
Comfort Suites Louisville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Cherokee Seneca

Find the best Cherokee Seneca areas for the activities you enjoy most.
Louisville showing signage and street scenes as well as a small group of people

Downtown Louisville

The cultural heart of the city beats with baseball, boxing and music, with sporting fields, live bands and a center for Muhammad Ali, the city’s most famous son.

Jeffersontown

Jeffersontown is known for its abundant dining options, and you can plan a trip to Jeffersontown Commons Shopping Center and Bluegrass Indoor Karting while you're in town.

Fairgrounds

While visiting Fairgrounds, you might make a stop by sights like Freedom Hall and Kentucky Kingdom.

St. Matthews

St. Matthews is noteworthy for its shopping, and you can make a stop at top attractions like Mall St. Matthews and Saint Matthews Pavilion Shopping Center.

Conrad Caldwell House featuring signage and heritage elements

Old Louisville

Old Louisville is known for its ample dining options, and you can make a stop by Ohio River Valley and Conrad-Caldwell House Museum while in the area.

Top Cherokee Seneca Hotel Reviews

Wingate by Wyndham Louisville Fair and Expo

Wingate by Wyndham Louisville Fair and Expo

10/10 Excellent
"This place was super clean and everyone we encountered was super friendly. Every time we went out or came in and walked by the front desk we were spoken to and asked about the things we said we were out doing that night. They offered us an upgrade on our room because of it being our anniversary."
Bethany 1-night trip
Posted 1 day ago
Wingate by Wyndham Louisville Fair and Expo

Frequently asked questions

What is Cherokee Seneca like?
You'll be sure to have fun exploring Louisville's Cherokee Seneca neighbourhood.
If I need to cancel my hotel reservation in Cherokee Seneca, will I receive a refund?
Yes, you'll find most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to review the best deals in Cherokee Seneca.
What is there to do around this Louisville neighbourhood?
Peterson-Dumesnil House, Historic Frankfort Avenue and Colonel Sanders' Grave are just a few of the places to visit in and around Cherokee Seneca. Muhammad Ali Gravesite and Mid City Mall Shopping Center are also worth a visit when you're out sightseeing in Louisville.

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