A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

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Our top choices for Defiance apartments

1. Great for Business Travelers! Pool + Gym

Great for Business Travelers! Pool + Gym
O'Fallon
7.0 out of 10, Good, (2 reviews)
"Property was dirty, kitchen hadn’t been cleaned. Microwave had food spilled all over inside. Place felt grimy."
United States
Jenny D.
The price is HK$1,326
HK$1,682 total
includes taxes & fees
12 Nov - 13 Nov
Great for Business Travelers! Pool + Gym

2. Stylish1BRStudioCleanQuietandCozy

Stylish1BRStudioCleanQuietandCozy
Saint Charles
10.0 out of 10, Exceptional, (3 reviews)
"Room was very clean with little to no issues at all. Host was super easy to work with and get information from. This spot is within 15-20minutes OR LESS to anything you’d need to do in the ofallon and surrounding areas. I’d book it again if I needed to."
United States
Mike S.
The price is HK$981
HK$2,372 total
includes taxes & fees
1 Nov - 2 Nov
Stylish1BRStudioCleanQuietandCozy

3. 2nd Street -Deck Suite (back entrance)

2nd Street -Deck Suite (back entrance)
Washington
10.0 out of 10, Exceptional, (11 reviews)
"The property was clean and comfortable and everything you may need is there, walking distance was very close to everything in the area. Communication with the host was easy and quick responses, overall it was a great place to stay!"
United States
Melinda
The price is HK$763
HK$1,489 total
includes taxes & fees
1 Nov - 2 Nov
2nd Street -Deck Suite (back entrance)

4. Enjoyable 2-bedroom apartment at St. Peters; Near STL

Enjoyable 2-bedroom apartment at St. Peters; Near STL
St. Peters
8.0 out of 10, Very good, (1 review)
"Very clean and comfortable. Pretty well-appointed. Could use an extra blanket or two. Overall good experience and would consider going again."
United States
Ronda S.
The price is HK$847
HK$2,221 total
includes taxes & fees
2 Nov - 3 Nov
Enjoyable 2-bedroom apartment at St. Peters; Near STL

5. Studio, sleeps 5, short drive to Hidden Valley Ski Resort, parks &concert venues

Studio, sleeps 5, short drive to Hidden Valley Ski Resort, parks &concert venues
Ballwin
7.8 out of 10, Good, (24 reviews)
"Rooms were clean and everything we needed for our stay."
United States
Keith K.
The price is HK$588
HK$1,101 total
includes taxes & fees
1 Dec - 2 Dec
Studio, sleeps 5, short drive to Hidden Valley Ski Resort, parks &concert venues

6. 2nd Street Loft - Riverview

2nd Street Loft - Riverview
Washington
10.0 out of 10, Exceptional, (21 reviews)
"Everything was great room was very clean"
United States
Chance W.
The price is HK$726
HK$1,403 total
includes taxes & fees
8 Nov - 9 Nov
2nd Street Loft - Riverview

7. The FarmHouse 3bd/2ba B&B in MO Wine Country & Katy Trail

The FarmHouse 3bd/2ba B&B in MO Wine Country & Katy Trail
Marthasville
8.4 out of 10, Very good, (5 reviews)
"This was the perfect place for my friends and I to stay in Marthasville. Lots of space and amenities. We did not use the complimentary breakfast, but is a great addition. Would recommend to anyone staying in the area. "
United States
Adam K.
The price is HK$1,960
HK$3,486 total
includes taxes & fees
11 Nov - 12 Nov
The FarmHouse 3bd/2ba B&B in MO Wine Country & Katy Trail

8. Studio | Lovely Suite Close to Edward Jones!

Studio | Lovely Suite Close to Edward Jones!
Westport
The price is HK$1,555
HK$1,937 total
includes taxes & fees
8 Nov - 9 Nov
Studio | Lovely Suite Close to Edward Jones!

9. 1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed

1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed
Westport
9.4 out of 10, Exceptional, (43 reviews)
"Great spot!"
United States
Anonymous traveller
The price is HK$512
HK$594 total
includes taxes & fees
2 Nov - 3 Nov
1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed

10. Home Near Main with Pet-Friendly Yard and Office

Home Near Main with Pet-Friendly Yard and Office
St. Charles Historic District
10.0 out of 10, Exceptional, (12 reviews)
"Very close to downtown St. Charles and the Kati Trail. The home is cute and bed is comfortable. Easy check in process and fenced in back yard was nice to have."
United States
Jessica S.
The price is HK$898
HK$2,045 total
includes taxes & fees
9 Nov - 10 Nov
Home Near Main with Pet-Friendly Yard and Office

11. Quiet 2BR Retreat on 7 Acres | Sleeps 6, Fast WiFi

Quiet 2BR Retreat on 7 Acres | Sleeps 6, Fast WiFi
Moscow Mills
10.0 out of 10, Exceptional, (14 reviews)
"Great place, nice neighborhood. "
United States
Julie L.
The price is HK$902
HK$1,961 total
includes taxes & fees
18 Nov - 19 Nov
Quiet 2BR Retreat on 7 Acres | Sleeps 6, Fast WiFi

12. Foundry Flat on Main with Free Parking

Foundry Flat on Main with Free Parking
St. Charles Historic District
10.0 out of 10, Exceptional, (1 review)
"Everything was exactly as described. St. Charles is an awesome place!"
United States
Michael
The price is HK$866
HK$2,354 total
includes taxes & fees
9 Nov - 10 Nov
Foundry Flat on Main with Free Parking

13. Historic Main St. Customs House Upstairs Apartment

Historic Main St. Customs House Upstairs Apartment
St. Charles Historic District
9.6 out of 10, Exceptional, (39 reviews)
"Lovely place to stay!"
United States
Margaret A.
The price is HK$974
HK$2,721 total
includes taxes & fees
3 Nov - 4 Nov
Historic Main St. Customs House Upstairs Apartment

14. Pet-Friendly Duplex on Historic Main

Pet-Friendly Duplex on Historic Main
St. Charles Historic District
10.0 out of 10, Exceptional, (26 reviews)
"Great location"
United States
todd p.
The price is HK$1,054
HK$2,201 total
includes taxes & fees
1 Dec - 2 Dec
Pet-Friendly Duplex on Historic Main

15. Dog-Friendly Studio on Historic Main Street

Dog-Friendly Studio on Historic Main Street
St. Charles Historic District
9.2 out of 10, Wonderful, (40 reviews)
"Had a wonderful stay. It was a Monday night so parking was very easy and the room was clean and comfortable. I would recommend this place 100% "
United States
Sarah C.
The price is HK$720
HK$1,700 total
includes taxes & fees
3 Nov - 4 Nov
Dog-Friendly Studio on Historic Main Street

16. 6th street 101 - Walk to Main St

6th street 101 - Walk to Main St
St. Charles Historic District
9.0 out of 10, Wonderful, (4 reviews)
"Excellent"
United States
Scott N.
The price is HK$777
HK$2,121 total
includes taxes & fees
1 Dec - 2 Dec
6th street 101 - Walk to Main St

17. Historic Main Street 1BR Near Dining and Nightlife

Historic Main Street 1BR Near Dining and Nightlife
St. Charles Historic District
9.2 out of 10, Wonderful, (26 reviews)
"Nice little apartment for a weekend away in St Charles."
United States
Teresa D.
The price is HK$1,017
HK$1,979 total
includes taxes & fees
2 Nov - 3 Nov
Historic Main Street 1BR Near Dining and Nightlife

18. Luxury 2-Bedroom Apt , St. Charles Retreat Smart Home Comfort & Modern Elegance

Luxury 2-Bedroom Apt , St. Charles Retreat Smart Home Comfort & Modern Elegance
St. Charles Historic District
10.0 out of 10, Exceptional, (1 review)
"Everything was new and loved the decor. Lots of extras that was really nice. Would stay again."
United States
Amy S.
The price is HK$1,640
HK$3,260 total
includes taxes & fees
1 Dec - 2 Dec
Luxury 2-Bedroom Apt , St. Charles Retreat Smart Home Comfort & Modern Elegance

19. The Lofts of North Main Street

The Lofts of North Main Street
St. Charles Historic District
9.6 out of 10, Exceptional, (196 reviews)
"Very cute place, walking distance to everything."
United States
Liberty A.
The price is HK$872
HK$1,829 total
includes taxes & fees
1 Nov - 2 Nov
The Lofts of North Main Street

20. Amazing Renovated Historic Loft on Main Street

Amazing Renovated Historic Loft on Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (72 reviews)
"This was a prime spot for downtown activities! Near everything and not far from STL. Would absolutely stay here again!"
United States
Rebecca F.
The price is HK$872
HK$1,908 total
includes taxes & fees
1 Nov - 2 Nov
Amazing Renovated Historic Loft on Main Street
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Defiance Hotel Reviews

Find out more about Defiance

Defiance Apartments information

Number of reviews
462
Accommodation
113 Apartments
Lowest Price
HK$594
Highest Price
HK$3,486

Frequently asked questions

What's it like to stay at an apartment in Defiance?
You'll find 10 apartments to choose from in Defiance for your holiday.
Why would you choose apartments instead of traditional hotels?
An apartment is often more spacious than a traditional hotel room and comes with a kitchen, so you can cook some of your meals. Apartments are ideal for families who want the conveniences of home, and also for couples who want to stay away from the tourist areas.
What's the top apartment I should consider for a stay in Defiance?
Here are some of the top apartments in the area: 2 Queen Beds | Non-Smoking, Kitchen: Situated in Maryland Heights , 18.7 mi/30.1 km from the heart of Defiance. Includes free WiFi and a Smart TV . 1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed: Located 18.7 mi/30.1 km away in Maryland Heights . Free WiFi and a Smart TV are included . The Lofts of North Main Street: Located in St. Charles , 19.2 mi/30.8 km away. Includes free WiFi, a sofa bed and a Smart TV . Access to on-site laundry facilities is available on site . Driftwood Den | Boho 2BR | Dog-Friendly: It's located in St. Charles , 19 mi/30.6 km from Defiance. Includes free WiFi .
How many apartments will I find in Defiance?
Expedia has 10 apartments to book in Defiance.
What can I expect from the weather in Defiance?
Weather is only one factor, but it can really affect your travel plans, especially if you are planning a longer stay in Defiance. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.
What are the must-see places to visit in Defiance?
August A. Busch Memorial Conservation Area and Missouri River are a couple of scenic spots to enjoy the outdoors, whereas Historic Daniel Boone Home and Heritage Center is one of the cultural attractions. While here, Yellow Farmhouse Winery and Chandler Hill Vineyards are other places worth a visit.
What's the best way to get to and around Defiance?
Knowing a bit about the transportation options can you save you a headache when you get to your destination. Fly into St. Louis, MO (SUS-Spirit of St. Louis), which is located 7.5 mi (12 km) from the heart of the city. Otherwise, look for flights into Lambert-St. Louis International Airport (STL), which is 23.5 mi (37.8 km) away. If you'd like to explore around the area, consider renting a car to explore more sights.

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