A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

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Our top choices for Defiance apartments

1. Great for Business Travelers! Pool + Gym

Great for Business Travelers! Pool + Gym
O'Fallon
The price is HK$1,096
HK$1,394 total
includes taxes & fees
5 Oct - 6 Oct
Great for Business Travelers! Pool + Gym

2. Stylish1BRStudioCleanQuietandCozy

Stylish1BRStudioCleanQuietandCozy
Saint Charles
10.0 out of 10, Exceptional, (3 reviews)
"Room was very clean with little to no issues at all. Host was super easy to work with and get information from. This spot is within 15-20minutes OR LESS to anything you’d need to do in the ofallon and surrounding areas. I’d book it again if I needed to."
United States
Mike S.
The price is HK$565
HK$1,949 total
includes taxes & fees
22 Sept - 23 Sept
Stylish1BRStudioCleanQuietandCozy

3. 2nd Street -Deck Suite (back entrance)

2nd Street -Deck Suite (back entrance)
Washington
10.0 out of 10, Exceptional, (9 reviews)
"Great comfortable mini apartment style."
United States
Ozzy
The price is HK$715
HK$1,462 total
includes taxes & fees
29 Sept - 30 Sept
2nd Street -Deck Suite (back entrance)

4. Studio, sleeps 4, patio, short drive to Ski Resort, Six Flags & concert venues

Studio, sleeps 4, patio, short drive to Ski Resort, Six Flags & concert venues
Ballwin
7.8 out of 10, Good, (23 reviews)
"Rooms were clean and everything we needed for our stay."
United States
Keith K.
The price is HK$529
HK$1,154 total
includes taxes & fees
21 Sept - 22 Sept
Studio, sleeps 4, patio, short drive to Ski Resort, Six Flags & concert venues

5. 2nd Street Loft - Riverview

2nd Street Loft - Riverview
Washington
10.0 out of 10, Exceptional, (17 reviews)
"Beautiful loft! Great location, walking distance to several restaurants on the river . "
United States
Christy D.
The price is HK$672
HK$1,369 total
includes taxes & fees
22 Sept - 23 Sept
2nd Street Loft - Riverview

6. Otto's Third | River View Loft by Borgia Church

Otto's Third | River View Loft by Borgia Church
Washington
The price is HK$2,380
HK$3,052 total
includes taxes & fees
22 Sept - 23 Sept
Otto's Third | River View Loft by Borgia Church

7. Family Friendly w/ Game Room in Quiet Neighborhood

Family Friendly w/ Game Room in Quiet Neighborhood
Wentzville
10.0 out of 10, Exceptional, (2 reviews)
"Nice house for our week in Lake St. Louis area. Accurate description of what you are getting and clean house. Would stay again if we are back in the area"
United States
Campbell W.
The price is HK$1,765
HK$3,757 total
includes taxes & fees
22 Sept - 23 Sept
Family Friendly w/ Game Room in Quiet Neighborhood

8. 1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed

1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed
Westport
9.6 out of 10, Exceptional, (41 reviews)
"Great spot!"
United States
Anonymous traveller
The price is HK$460
HK$534 total
includes taxes & fees
1 Oct - 2 Oct
1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed

9. Dog-Friendly 2BR | Walk to Main Street

Dog-Friendly 2BR | Walk to Main Street
Saint Charles
8.0 out of 10, Very good, (5 reviews)
"The best price-value ratio. Quiet neighborhood, close to the city center."
United States
Tamas P.
The price is HK$796
HK$2,212 total
includes taxes & fees
17 Sept - 18 Sept
Dog-Friendly 2BR | Walk to Main Street

10. Historic Main Street Studio | Dog-Friendly

Historic Main Street Studio | Dog-Friendly
St. Charles Historic District
9.2 out of 10, Wonderful, (38 reviews)
"Had a wonderful stay. It was a Monday night so parking was very easy and the room was clean and comfortable. I would recommend this place 100% "
United States
Sarah C.
The price is HK$644
HK$1,572 total
includes taxes & fees
17 Sept - 18 Sept
Historic Main Street Studio | Dog-Friendly

11. 6th street 101 - Walk to Main St

6th street 101 - Walk to Main St
St. Charles Historic District
10.0 out of 10, Exceptional, (3 reviews)
"Excellent"
United States
Scott N.
The price is HK$698
HK$2,133 total
includes taxes & fees
16 Sept - 17 Sept
6th street 101 - Walk to Main St

12. Historic Main St 2BR | Steps to Shops

Historic Main St 2BR | Steps to Shops
St. Charles Historic District
9.4 out of 10, Exceptional, (42 reviews)
"This property has a nice renovation while keeping a lot of its original character. Very clean and comfortable beds as well. The location couldn’t be better! We really enjoyed our stay."
United States
William O.
The price is HK$1,084
HK$3,118 total
includes taxes & fees
20 Sept - 21 Sept
Historic Main St 2BR | Steps to Shops

13. The Lofts of North Main Street

The Lofts of North Main Street
St. Charles Historic District
9.6 out of 10, Exceptional, (190 reviews)
"It was great! Clean and great communication with host."
United States
Natalie H.
The price is HK$872
HK$1,907 total
includes taxes & fees
16 Sept - 17 Sept
The Lofts of North Main Street

14. 1st Capitol Mansion - Suite 401

1st Capitol Mansion - Suite 401
St. Charles Historic District
7.4 out of 10, Good, (9 reviews)
"Nice property and a great location to all the shops and restaurants that St. Charles has to offer. The place was clean and nicely updated. Will definitely stay here again!"
United States
Emily L.
The price is HK$698
HK$1,886 total
includes taxes & fees
16 Sept - 17 Sept
1st Capitol Mansion - Suite 401

15. Prime Loft of Main Street

Prime Loft of Main Street
St. Charles Historic District
9.8 out of 10, Exceptional, (117 reviews)
"Host was great. The cutest place in the perfect spot! "
United States
Anonymous traveller
The price is HK$763
HK$1,774 total
includes taxes & fees
16 Sept - 17 Sept
Prime Loft of Main Street

16. Main Street 2BR - Walk to Dining & Riverfront

Main Street 2BR - Walk to Dining & Riverfront
St. Charles Historic District
9.4 out of 10, Exceptional, (3 reviews)
"This is our new favorite property in St. Charles. Between the location, size of the space and the designated parking spot, we will definitely be staying here again!"
United States
Billi G.
The price is HK$1,045
HK$2,566 total
includes taxes & fees
22 Sept - 23 Sept
Main Street 2BR - Walk to Dining & Riverfront

17. Walk to Main | Pet-Friendly Yard & Workspace

Walk to Main | Pet-Friendly Yard & Workspace
St. Charles Historic District
10.0 out of 10, Exceptional, (11 reviews)
"Very close to downtown St. Charles and the Kati Trail. The home is cute and bed is comfortable. Easy check in process and fenced in back yard was nice to have."
United States
Jessica S.
The price is HK$999
HK$2,168 total
includes taxes & fees
20 Sept - 21 Sept
Walk to Main | Pet-Friendly Yard & Workspace

18. Historic Main St. Customs House Upstairs Apartment

Historic Main St. Customs House Upstairs Apartment
St. Charles Historic District
9.6 out of 10, Exceptional, (39 reviews)
"Lovely place to stay!"
United States
Margaret A.
The price is HK$1,176
HK$2,952 total
includes taxes & fees
30 Sept - 1 Oct
Historic Main St. Customs House Upstairs Apartment

19. Amazing Renovated Historic Loft on Main Street

Amazing Renovated Historic Loft on Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (68 reviews)
"Lovely accommodations, very clean, well equipped, great location. "
United States
Emily B.
The price is HK$1,090
HK$2,174 total
includes taxes & fees
20 Sept - 21 Sept
Amazing Renovated Historic Loft on Main Street

20. Historic Main St 1BR | Walk to Dining & Nightlife

Historic Main St 1BR | Walk to Dining & Nightlife
St. Charles Historic District
9.2 out of 10, Wonderful, (24 reviews)
"Great place, very fun. I’d stay again for sure. "
United States
Michael C.
The price is HK$1,059
HK$2,112 total
includes taxes & fees
17 Sept - 18 Sept
Historic Main St 1BR | Walk to Dining & Nightlife
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Defiance Hotel Reviews

Find out more about Defiance

Defiance Apartments information

Number of reviews
609
Accommodation
113 Apartments
Lowest Price
HK$534
Highest Price
HK$3,757

Frequently asked questions

What's it like to stay at an apartment in Defiance?
You'll find 10 apartments to choose from in Defiance for your holiday.
Why would you choose apartments instead of traditional hotels?
An apartment is often more spacious than a traditional hotel room and comes with a kitchen, so you can cook some of your meals. Apartments are ideal for families who want the conveniences of home, and also for couples who want to stay away from the tourist areas.
What's the top apartment I should consider for a stay in Defiance?
Here are some of the top apartments in the area: 2 Queen Beds | Non-Smoking, Kitchen: Situated in Maryland Heights , 18.7 mi/30.1 km from the heart of Defiance. Includes free WiFi and a Smart TV . 1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed: Located 18.7 mi/30.1 km away in Maryland Heights . Free WiFi and a Smart TV are included . The Lofts of North Main Street: Located in St. Charles , 19.2 mi/30.8 km away. Includes free WiFi, a sofa bed and a Smart TV . Access to on-site laundry facilities is available on site . Driftwood Den | Boho 2BR | Dog-Friendly: 19 mi/30.6 km away in St. Charles . Amenities include free WiFi . Historic Main Street Studio | Dog-Friendly: It's situated in St. Charles , 19.1 mi/30.8 km from Defiance.
How many apartments will I find in Defiance?
Expedia has 10 apartments to book in Defiance.
What can I expect from the weather in Defiance?
Weather is only one factor, but it can really affect your travel plans, especially if you are planning a longer stay in Defiance. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.
What are the must-see places to visit in Defiance?
August A. Busch Memorial Conservation Area and Missouri River are a couple of scenic spots to enjoy the outdoors, whereas Historic Daniel Boone Home and Heritage Center is one of the cultural attractions. While here, Yellow Farmhouse Winery and Chandler Hill Vineyards are other places worth a visit.
What's the best way to get to and around Defiance?
Knowing a bit about the transportation options can you save you a headache when you get to your destination. Fly into St. Louis, MO (SUS-Spirit of St. Louis), which is located 7.5 mi (12 km) from the heart of the city. Otherwise, look for flights into Lambert-St. Louis International Airport (STL), which is 23.5 mi (37.8 km) away. If you'd like to explore around the area, consider renting a car to explore more sights.

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