A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

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Our top choices for Defiance apartments

1. The Foundry Flat | Industrial-Inspired 2-Bedroom

The Foundry Flat | Industrial-Inspired 2-Bedroom
St. Charles Historic District
The price is HK$974
HK$2,500 total
includes taxes & fees
31 Aug - 1 Sept
The Foundry Flat | Industrial-Inspired 2-Bedroom

2. Great for Business Travelers! Pool + Gym

Great for Business Travelers! Pool + Gym
O'Fallon
The price is HK$936
HK$1,261 total
includes taxes & fees
2 Aug - 3 Aug
Great for Business Travelers! Pool + Gym

3. Chic 1- Queen Bed, Non Smoking-Near Airport, Kitchen, Twin Bed

Chic 1- Queen Bed, Non Smoking-Near Airport, Kitchen, Twin Bed
St. Louis
9.0 out of 10, Wonderful, (13 reviews)
"This was absolutely perfect and reasonable pricing I surely will be back "
United States
David G.
The price is HK$667
HK$875 total
includes taxes & fees
8 Aug - 9 Aug
Chic 1- Queen Bed, Non Smoking-Near Airport, Kitchen, Twin Bed

4. Duplex Hideaway in St. Charles, MO

Duplex Hideaway in St. Charles, MO
St. Charles Historic District
9.8 out of 10, Exceptional, (7 reviews)
"I will stay here again. It was a great location for my visit. Lots of room and amenities. Highly recommend this location if you are visiting the St Louis area. Barely a mile to get to Hwy 70, so easy access to St Louis, St Peter's, Wentzville etc. Maybe two blocks from Historic St Charles and Ameristar Casino."
United States
Karen M.
The price is HK$932
HK$2,098 total
includes taxes & fees
2 Aug - 3 Aug
Duplex Hideaway in St. Charles, MO

5. 2 Queen Beds | Non-Smoking, Kitchen

2 Queen Beds | Non-Smoking, Kitchen
Westport
9.8 out of 10, Exceptional, (38 reviews)
"Fantastic place!"
United States
Anonymous traveller
The price is HK$756
HK$876 total
includes taxes & fees
3 Aug - 4 Aug
2 Queen Beds | Non-Smoking, Kitchen

6. The Driftwood Den | Boho-Inspired 2-Bedroom

The Driftwood Den | Boho-Inspired 2-Bedroom
St. Charles Historic District
10.0 out of 10, Exceptional, (3 reviews)
"Loved our stay here. Clean, comfortable, convenient. Couldn’t have been easier, in all aspects. Already plan to stay there again!!!"
United States
Kourtney S.
The price is HK$974
HK$2,469 total
includes taxes & fees
31 Aug - 1 Sept
The Driftwood Den | Boho-Inspired 2-Bedroom

7. Amazing Renovated Historic Loft on Main Street

Amazing Renovated Historic Loft on Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (67 reviews)
"Lovely accommodations, very clean, well equipped, great location. "
United States
Emily B.
The price is HK$981
HK$2,056 total
includes taxes & fees
4 Aug - 5 Aug
Amazing Renovated Historic Loft on Main Street

8. The Lofts of North Main Street

The Lofts of North Main Street
St. Charles Historic District
9.6 out of 10, Exceptional, (181 reviews)
"Great place to stay. Our go to when visiting St.Charles or STL"
United States
jeramy p.
The price is HK$981
HK$2,033 total
includes taxes & fees
3 Aug - 4 Aug
The Lofts of North Main Street

9. Prime Loft of Main Street

Prime Loft of Main Street
St. Charles Historic District
9.8 out of 10, Exceptional, (114 reviews)
"Host was great. The cutest place in the perfect spot! "
United States
Anonymous traveller
The price is HK$981
HK$2,056 total
includes taxes & fees
2 Aug - 3 Aug
Prime Loft of Main Street

10. Historic Main St. Customs House Upstairs Apartment

Historic Main St. Customs House Upstairs Apartment
St. Charles Historic District
9.6 out of 10, Exceptional, (38 reviews)
"Lovely place to stay!"
United States
Margaret A.
The price is HK$1,270
HK$3,123 total
includes taxes & fees
2 Aug - 3 Aug
Historic Main St. Customs House Upstairs Apartment

11. Walk to Main St | Pet-Friendly Apt

Walk to Main St | Pet-Friendly Apt
St. Charles Historic District
8.6 out of 10, Excellent, (16 reviews)
"Property was as advertised. Perfect for my needs, clean, quiet and convenient. Loved Historic St. Charles. Would recommend anytime! Thank you! "
United States
Brian B.
The price is HK$1,059
HK$2,460 total
includes taxes & fees
11 Aug - 12 Aug
Walk to Main St | Pet-Friendly Apt

12. Charming Duplex on Main

Charming Duplex on Main
St. Charles Historic District
10.0 out of 10, Exceptional, (23 reviews)
"Great location"
United States
todd p.
The price is HK$932
HK$2,097 total
includes taxes & fees
2 Aug - 3 Aug
Charming Duplex on Main

13. Stay on Main Historic Studio

Stay on Main Historic Studio
St. Charles Historic District
9.2 out of 10, Wonderful, (36 reviews)
"Had a wonderful stay. It was a Monday night so parking was very easy and the room was clean and comfortable. I would recommend this place 100% "
United States
Sarah C.
The price is HK$847
HK$1,790 total
includes taxes & fees
9 Aug - 10 Aug
Stay on Main Historic Studio

14. 6th street 101 - Walk to Main St

6th street 101 - Walk to Main St
St. Charles Historic District
10.0 out of 10, Exceptional, (3 reviews)
"Excellent"
United States
Scott N.
The price is HK$776
HK$2,230 total
includes taxes & fees
9 Aug - 10 Aug
6th street 101 - Walk to Main St

15. Great for Business Travelers! Studio Suite Near Edward Jones! Free Breakfast!

Great for Business Travelers! Studio Suite Near Edward Jones! Free Breakfast!
Westport
9.6 out of 10, Exceptional, (4 reviews)
"It was an easy experience renting this place"
United States
Dominic M.
The price is HK$1,411
HK$1,833 total
includes taxes & fees
30 Aug - 31 Aug
Great for Business Travelers! Studio Suite Near Edward Jones! Free Breakfast!

16. Main Street Apartment

Main Street Apartment
St. Charles Historic District
9.4 out of 10, Exceptional, (40 reviews)
"Great location for shopping and a lot of restaurants nearby. Beds were very comfortable. "
United States
Brooke I.
The price is HK$1,271
HK$3,513 total
includes taxes & fees
2 Aug - 3 Aug
Main Street Apartment

17. Quiet Neighborhood-Near Eats & Shops-Airport!

Quiet Neighborhood-Near Eats & Shops-Airport!
Brookside
10.0 out of 10, Exceptional, (2 reviews)
"This was an awesome place for 9 of us- plenty of rooms to sleep and bathrooms. The renter was very kind"
United States
Janet
The price is HK$1,608
HK$3,631 total
includes taxes & fees
4 Aug - 5 Aug
Quiet Neighborhood-Near Eats & Shops-Airport!

18. 2 Bdr Upstairs Apt Walking Distance to Main St

2 Bdr Upstairs Apt Walking Distance to Main St
Saint Charles
8.0 out of 10, Very good, (5 reviews)
"The best price-value ratio. Quiet neighborhood, close to the city center."
United States
Tamas P.
The price is HK$966
HK$2,431 total
includes taxes & fees
2 Aug - 3 Aug
2 Bdr Upstairs Apt Walking Distance to Main St

19. Family Home: Game Room & Huge Yard, Airport

Family Home: Game Room & Huge Yard, Airport
Maryland Heights
10.0 out of 10, Exceptional, (1 review)
"Very nice"
United States
Steven S.
Family Home: Game Room & Huge Yard, Airport

20. 3BR Family+Game Retreat 8 min STL Airport/Westport

3BR Family+Game Retreat 8 min STL Airport/Westport
Maryland Heights
9.0 out of 10, Wonderful, (10 reviews)
"Great stay! We had everything we needed and the communication was perfect!"
United States
Melodie B.
The price is HK$1,376
HK$3,322 total
includes taxes & fees
3 Aug - 4 Aug
3BR Family+Game Retreat 8 min STL Airport/Westport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Defiance Hotel Reviews

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Defiance Apartments information

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Frequently asked questions

What's it like to stay at an apartment in Defiance?
You'll find 10 apartments to choose from in Defiance for your holiday.
Why would you choose apartments instead of traditional hotels?
An apartment is often more spacious than a traditional hotel room and comes with a kitchen, so you can cook some of your meals. Apartments are ideal for families who want the conveniences of home, and also for couples who want to stay away from the tourist areas.
What's the top apartment I should consider for a stay in Defiance?
Here are some of the top apartments in the area: The Lofts of North Main Street: Located in St. Charles , 19.2 mi/30.8 km from the heart of Defiance. Includes free WiFi, a sofa bed and a Smart TV . Access to on-site laundry facilities is available on site . 2 Queen Beds | Non-Smoking, Kitchen: Located 18.7 mi/30.1 km away in Maryland Heights . Free WiFi and a Smart TV are included . 1 Queen Bed | Non-Smoking, Kitchen: It's situated in Maryland Heights , 18.7 mi/30.1 km away. Includes free WiFi and a Smart TV . Prime Loft of Main Street: Located 19.2 mi/30.9 km away in St. Charles . Free WiFi, a sofa bed and a Smart TV are included . Access to on-site laundry facilities is available on site . Remodeled Kirkwood Guest house: Located in Kirkwood , 20 mi/32.2 km from Defiance. Includes a balcony, a sofa bed and a Smart TV . On-site laundry facilities and 1 hot tub are on site .
How many apartments will I find in Defiance?
Expedia has 10 apartments to book in Defiance.
What can I expect from the weather in Defiance?
Weather is only one factor, but it can really affect your travel plans, especially if you are planning a longer stay in Defiance. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.
What are the must-see places to visit in Defiance?
August A. Busch Memorial Conservation Area and Missouri River are a couple of scenic spots to enjoy the outdoors, whereas Historic Daniel Boone Home and Heritage Center is one of the cultural attractions. While here, Chandler Hill Vineyards and Sugar Creek Winery are other places worth a visit.
What's the best way to get to and around Defiance?
Knowing a bit about the transportation options can you save you a headache when you get to your destination. Fly into St. Louis, MO (SUS-Spirit of St. Louis), which is located 7.5 mi (12 km) from the heart of the city. Otherwise, look for flights into Lambert-St. Louis International Airport (STL), which is 23.5 mi (37.8 km) away. If you'd like to explore around the area, consider renting a car to explore more sights.

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