A rocky stream surrounded by trees and foliage.

Cape Girardeau County Holiday Rentals

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Our top choices for Cape Girardeau County holiday rentals

A living room with a TV, a fireplace, a sofa, and wall art.

1. Little Blue Cottage on Spanish

Little Blue Cottage on Spanish
Cape Girardeau
8.4 out of 10, Very good, (59 reviews)
"Great cute place. "
United States
Jeremy W.
The price is HK$635
HK$848 total
includes taxes & fees
26 Oct - 27 Oct
Little Blue Cottage on Spanish
A bedroom with a bed, a bottle of J. Roget champagne, two glasses, and a plate with snacks.

2. The Cottage, Rusted Route Farms

The Cottage, Rusted Route Farms
Jackson
10.0 out of 10, Exceptional, (3 reviews)
"This Cottage was very nice and clean and well maintained. The meat tray that we ordered and the breakfast tray was beyond Fabulous!!! My husband is still talking about it. . .Rick & Renee Christman"
United States
Renee C.
The price is HK$980
HK$1,561 total
includes taxes & fees
15 Nov - 16 Nov
The Cottage, Rusted Route Farms
A kitchen with grey cabinets, a stainless steel dishwasher, a microwave, and an oven.

3. Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & Hospitals

Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & Hospitals
Cape Girardeau
The price is HK$854
HK$1,529 total
includes taxes & fees
27 Oct - 28 Oct
Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & Hospitals
Exterior

4. Purple Tiny House with Fire pit & Nature

Purple Tiny House with Fire pit & Nature
Cape Girardeau
10.0 out of 10, Exceptional, (1 review)
"First time staying in the purple house, second time staying at the property. 10/10 recommend"
United States
Shawn A.
The price is HK$1,082
HK$1,591 total
includes taxes & fees
26 Oct - 27 Oct
Purple Tiny House with Fire pit & Nature
Exterior

5. Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly

Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly
Cape Girardeau
10.0 out of 10, Exceptional, (3 reviews)
"The house was very clean and Will kept and the whole property was well maintained. It was very comfortable and nicely decorated. The host was very responsive and helpful! Would definitely stay again and recommend."
United States
Sara C.
The price is HK$1,218
HK$1,781 total
includes taxes & fees
26 Oct - 27 Oct
Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly
A compact kitchen with wooden cabinets and a dining area with a table and chairs.

6. Villa B offers peace and quiet with beautiful views of the countryside.

Villa B offers peace and quiet with beautiful views of the countryside.
Jackson
9.8 out of 10, Exceptional, (16 reviews)
"We were only there for 1 night for a business trip but it was perfect for our stay. Very clean and comfortable and the host was onsite to welcome us. She even gave us a tip on the best place nearby for dinner that we will be going to any time we can in the future. I would gladly stay here again for future trips."
United States
Terry H.
The price is HK$1,176
HK$1,416 total
includes taxes & fees
26 Oct - 27 Oct
Villa B offers peace and quiet with beautiful views of the countryside.
A kitchen with wooden cabinets, a black refrigerator, a microwave, a stove, and a ceiling fan. There are three stools at the island.

7. Relax in the country at Countryside Villas! - Villa A

Relax in the country at Countryside Villas! - Villa A
Jackson
10.0 out of 10, Exceptional, (39 reviews)
"Great place to stay, felt like home away from home. "
United States
Brittany
The price is HK$1,176
HK$1,416 total
includes taxes & fees
26 Oct - 27 Oct
Relax in the country at Countryside Villas! - Villa A
Private kitchen

8. Pleasant 2-bedroom mobile home with AC /heat in Friedheim 2 Queen beds 1 Bath.

Pleasant 2-bedroom mobile home with AC /heat in Friedheim 2 Queen beds 1 Bath.
Friedheim
The price is HK$1,235
HK$1,907 total
includes taxes & fees
26 Oct - 27 Oct
Pleasant 2-bedroom mobile home with AC /heat in Friedheim 2 Queen beds 1 Bath.
A row of colorful houses with a clear sky and trees in the background.

9. Enchanted Mermaid A-Frame | Creek + Fire pit | Pet Friendly

Enchanted Mermaid A-Frame | Creek + Fire pit | Pet Friendly
Cape Girardeau
The price is HK$1,308
HK$1,845 total
includes taxes & fees
26 Oct - 27 Oct
Enchanted Mermaid A-Frame | Creek + Fire pit | Pet Friendly
Ground floor of the Euro

10. The Little Château | Woodland Escape

The Little Château | Woodland Escape
Cape Girardeau
The price is HK$1,218
HK$1,742 total
includes taxes & fees
26 Oct - 27 Oct
The Little Château | Woodland Escape
A modern living room with a wooden ceiling, a stone fireplace, a TV mounted on the wall, and a bar area with stools.

11. The Twisted Sassafras Treehouse

The Twisted Sassafras Treehouse
Cape Girardeau
10.0 out of 10, Exceptional, (40 reviews)
"The hosts were excellent."
United States
Jason L.
The price is HK$1,758
HK$2,802 total
includes taxes & fees
26 Oct - 27 Oct
The Twisted Sassafras Treehouse
Exterior

12. The Little Cape Lofted Cottage | Creek & Nature

The Little Cape Lofted Cottage | Creek & Nature
Cape Girardeau
9.0 out of 10, Wonderful, (2 reviews)
"It was very clean and had a good feel. It was well stocked. I appreciated the cute little ice tray in the freezer that was full. I also appreciated 4 waters in the fridge. The bed on the loft upstairs was atrocious. You can feel the springs through the mattress. The downstairs bed was good. The pillows were fantastic! I’m a pillow snob. We needed a quick place to land for a church function so I can’t say much about the outside amenities as we weren’t there much. But it was a beautifully tucked...
United States
Trisha S.
The price is HK$1,263
HK$1,798 total
includes taxes & fees
26 Oct - 27 Oct
The Little Cape Lofted Cottage | Creek & Nature
A log cabin interior with a stone fireplace, leather sofa, and a mounted deer head.

13. Gorgeous 1856 Log Cabin, Completely Renovated

Gorgeous 1856 Log Cabin, Completely Renovated
Jackson
10.0 out of 10, Exceptional, (6 reviews)
"incredible place. I was there for work, but it was a really nice relaxing area to retreat too, and also get some work done in a serene environment. It would be an incredible place for an entire family. And, a good place for friends to get together."
United States
Chandler G.
The price is HK$1,569
HK$2,455 total
includes taxes & fees
26 Oct - 27 Oct
Gorgeous 1856 Log Cabin, Completely Renovated
A two-story house with a front porch, a small garden, and a white picket fence.

14. 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Cape Girardeau
8.8 out of 10, Excellent, (46 reviews)
"Will definitely book again! Great location, comfortable stay."
United States
Pynktoria !.
The price is HK$1,405
HK$2,472 total
includes taxes & fees
26 Oct - 27 Oct
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
A modern kitchen with a large island, white cabinetry, and a brick accent wall.

15. Beautifully Renovated Farmhouse in Jackson, MO

Beautifully Renovated Farmhouse in Jackson, MO
Jackson
9.4 out of 10, Exceptional, (3 reviews)
" great stay,property landscape nicely manicured, quiet and relaxing inside and outside of the the dwelling."
United States
Sandy S.
The price is HK$1,569
HK$2,455 total
includes taxes & fees
26 Oct - 27 Oct
Beautifully Renovated Farmhouse in Jackson, MO
A house with a backyard swimming pool, outdoor furniture, and a barbecue area.

16. 4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Cape Girardeau
9.8 out of 10, Exceptional, (11 reviews)
"Nice place, great times"
United States
Jace W.
The price is HK$2,816
HK$4,555 total
includes taxes & fees
26 Oct - 27 Oct
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
A rustic interior with exposed brick walls, wooden railings, and a hanging floral chandelier.

17. The Atrium - A Boutique Hotel

The Atrium - A Boutique Hotel
2.0 star property
Perryville
9.4 out of 10, Exceptional, (11 reviews)
"What an amazing little suite wrapped in a very thought-filled overall venue. Very unique room with a so many details. The overall building with fire pit, game rooms, and local vendor items…all was quite amazing. Every element is thought out very well. It is very convenient and overall comfortable. It was a great getaway."
United States
Brian
The price is HK$692
HK$792 total
includes taxes & fees
26 Oct - 27 Oct
The Atrium - A Boutique Hotel
A wooden cabin with a green door, a number '2' sign, a small porch with a wooden railing, and a wall-mounted lantern.

18. 3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!

3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!
Makanda
9.8 out of 10, Exceptional, (78 reviews)
"Very clean and comfortable stay"
United States
Alison K.
The price is HK$808
HK$1,515 total
includes taxes & fees
26 Oct - 27 Oct
3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!
A small, single-story building with a wooden exterior and large windows.

19. The Rested Duck Mallard Room

The Rested Duck Mallard Room
Olive Branch
9.4 out of 10, Exceptional, (31 reviews)
"This is an excellent place to stay. With a nice lake right across the street. If i. In the are i will stay again for sure"
United States
mike b.
The price is HK$882
HK$1,101 total
includes taxes & fees
26 Oct - 27 Oct
The Rested Duck Mallard Room
A cozy room with a wooden table and chairs, a large window, and a door with a sign.

20. Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake
Olive Branch
9.8 out of 10, Exceptional, (44 reviews)
"Super communication! . Accommodating. Nice people"
United States
JASEN
The price is HK$882
HK$1,101 total
includes taxes & fees
26 Oct - 27 Oct
Cozy cabins on beautiful Horseshoe Lake
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cape Girardeau County Hotel Reviews

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

10/10 Excellent
"The room was clean, staff was friendly and breakfast was delicious"
Ashley 3-night trip
Posted 6 hours ago
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG