A rocky stream surrounded by trees and foliage.

Cape Girardeau County Holiday Rentals

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Our top choices for Cape Girardeau County holiday rentals

A kitchen with wooden cabinets, a black refrigerator, a microwave, a stove, and a ceiling fan. There are three stools at the island.

1. Relax in the country at Countryside Villas! - Villa A

Relax in the country at Countryside Villas! - Villa A
Jackson
10.0 out of 10, Exceptional, (37 reviews)
"Great place to stay, felt like home away from home. "
United States
Brittany
The price is HK$1,176
HK$1,416 total
includes taxes & fees
7 Sept - 8 Sept
Relax in the country at Countryside Villas! - Villa A
A modern living room with a wooden ceiling, a stone fireplace, a TV mounted on the wall, and a bar area with stools.

2. The Twisted Sassafras Treehouse

The Twisted Sassafras Treehouse
Cape Girardeau
10.0 out of 10, Exceptional, (36 reviews)
"Amazing stay! Everything was perfect."
United States
Wayne F.
The price is HK$1,952
HK$3,023 total
includes taxes & fees
21 Sept - 22 Sept
The Twisted Sassafras Treehouse
A compact kitchen with wooden cabinets and a dining area with a table and chairs.

3. Villa B offers peace and quiet with beautiful views of the countryside.

Villa B offers peace and quiet with beautiful views of the countryside.
Jackson
9.8 out of 10, Exceptional, (14 reviews)
"We were only there for 1 night for a business trip but it was perfect for our stay. Very clean and comfortable and the host was onsite to welcome us. She even gave us a tip on the best place nearby for dinner that we will be going to any time we can in the future. I would gladly stay here again for future trips."
United States
Terry H.
The price is HK$1,176
HK$1,416 total
includes taxes & fees
7 Sept - 8 Sept
Villa B offers peace and quiet with beautiful views of the countryside.
A two-story house with a front porch, a small garden, and a white picket fence.

4. 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Cape Girardeau
8.8 out of 10, Excellent, (43 reviews)
"Will definitely book again! Great location, comfortable stay."
United States
Pynktoria !.
The price is HK$1,404
HK$2,456 total
includes taxes & fees
7 Sept - 8 Sept
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
A bedroom with a bed, a bottle of J. Roget champagne, two glasses, and a plate with snacks.

5. The Cottage, Rusted Route Farms

The Cottage, Rusted Route Farms
Jackson
10.0 out of 10, Exceptional, (3 reviews)
"This Cottage was very nice and clean and well maintained. The meat tray that we ordered and the breakfast tray was beyond Fabulous!!! My husband is still talking about it. . .Rick & Renee Christman"
United States
Renee C.
The price is HK$980
HK$1,552 total
includes taxes & fees
7 Sept - 8 Sept
The Cottage, Rusted Route Farms
A log cabin interior with a stone fireplace, leather sofa, and a mounted deer head.

6. Gorgeous 1856 Log Cabin, Completely Renovated

Gorgeous 1856 Log Cabin, Completely Renovated
Jackson
10.0 out of 10, Exceptional, (5 reviews)
"incredible place. I was there for work, but it was a really nice relaxing area to retreat too, and also get some work done in a serene environment. It would be an incredible place for an entire family. And, a good place for friends to get together."
United States
Chandler G.
The price is HK$1,568
HK$2,431 total
includes taxes & fees
8 Sept - 9 Sept
Gorgeous 1856 Log Cabin, Completely Renovated

7. Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly

Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly
Cape Girardeau
10.0 out of 10, Exceptional, (2 reviews)
"The house was very clean and Will kept and the whole property was well maintained. It was very comfortable and nicely decorated. The host was very responsive and helpful! Would definitely stay again and recommend."
United States
Sara C.
The price is HK$1,217
HK$1,765 total
includes taxes & fees
11 Sept - 12 Sept
Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly
A house with a backyard swimming pool, outdoor furniture, and a barbecue area.

8. 4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Cape Girardeau
9.8 out of 10, Exceptional, (11 reviews)
"Nice place, great times"
United States
Jace W.
The price is HK$2,470
HK$4,086 total
includes taxes & fees
7 Sept - 8 Sept
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
A living room with a TV, a fireplace, a sofa, and wall art.

9. Little Blue Cottage on Spanish

Little Blue Cottage on Spanish
Cape Girardeau
8.4 out of 10, Very good, (58 reviews)
"Great cute place. "
United States
Jeremy W.
The price is HK$635
HK$848 total
includes taxes & fees
7 Sept - 8 Sept
Little Blue Cottage on Spanish
A modern kitchen with a large island, white cabinetry, and a brick accent wall.

10. Beautifully Renovated Farmhouse in Jackson, MO

Beautifully Renovated Farmhouse in Jackson, MO
Jackson
9.4 out of 10, Exceptional, (3 reviews)
" great stay,property landscape nicely manicured, quiet and relaxing inside and outside of the the dwelling."
United States
Sandy S.
The price is HK$1,568
HK$2,431 total
includes taxes & fees
10 Sept - 11 Sept
Beautifully Renovated Farmhouse in Jackson, MO

11. The Little Cape Lofted Cottage | Creek & Nature

The Little Cape Lofted Cottage | Creek & Nature
Cape Girardeau
10.0 out of 10, Exceptional, (1 review)
"The tiny house was adorable, clean, and everything we expected. We can’t wait to stay in the others. We definitely recommend staying here. Lisa and Holly have done a wonderful job. Holly was great at getting back to me. Loved everything about our stay and the trip. Thank you so much"
United States
Kim K.
The price is HK$1,136
HK$1,672 total
includes taxes & fees
7 Sept - 8 Sept
The Little Cape Lofted Cottage | Creek & Nature

12. Enchanted Mermaid A-Frame | Creek + Fire pit | Pet Friendly

Enchanted Mermaid A-Frame | Creek + Fire pit | Pet Friendly
Cape Girardeau
The price is HK$1,177
HK$1,722 total
includes taxes & fees
7 Sept - 8 Sept
Enchanted Mermaid A-Frame | Creek + Fire pit | Pet Friendly

13. The Little Château | Woodland Escape

The Little Château | Woodland Escape
Cape Girardeau
The price is HK$1,095
HK$1,629 total
includes taxes & fees
7 Sept - 8 Sept
The Little Château | Woodland Escape
A rustic interior with exposed brick walls, wooden railings, and a hanging floral chandelier.

14. The Atrium - A Boutique Hotel

The Atrium - A Boutique Hotel
2.0 star property
Perryville
9.8 out of 10, Exceptional, (6 reviews)
"What an amazing little suite wrapped in a very thought-filled overall venue. Very unique room with a so many details. The overall building with fire pit, game rooms, and local vendor items…all was quite amazing. Every element is thought out very well. It is very convenient and overall comfortable. It was a great getaway."
United States
Brian
The price is HK$593
HK$1,251 total
includes taxes & fees
7 Sept - 8 Sept
The Atrium - A Boutique Hotel
A modern kitchen with a large island, stainless steel appliances, and exposed brick walls.

15. Urban Lofts

Urban Lofts
3.0 star property
Perryville
9.4 out of 10, Exceptional, (22 reviews)
"Beautiful place and staff was amazing!"
United States
Grace
The price is HK$1,581
HK$2,438 total
includes taxes & fees
7 Sept - 8 Sept
Urban Lofts
A log cabin with a metal roof, two windows, a door, and a porch with two rocking chairs and a small table.

16. Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Anna
10.0 out of 10, Exceptional, (424 reviews)
"Cabin was cute and cozy!! "
United States
Anonymous traveller
The price is HK$917
HK$1,571 total
includes taxes & fees
7 Sept - 8 Sept
Rest, Relax and Renew. Our log cabin experience awaits your arrival.
A red barn with a sloped roof, surrounded by a grassy field and trees.

17. The Weber Farm - Enjoy a beautiful 100 acre farm!

The Weber Farm - Enjoy a beautiful 100 acre farm!
Frohna
10.0 out of 10, Exceptional, (34 reviews)
"Wonderful time! "
United States
Alison C.
The price is HK$706
HK$1,285 total
includes taxes & fees
10 Sept - 11 Sept
The Weber Farm - Enjoy a beautiful 100 acre farm!
A red barn-style building with a sign reading "Farm Market" and a stage with chairs and a table.

18. Rendelman Orchard's Farm Stay

Rendelman Orchard's Farm Stay
Alto Pass
9.8 out of 10, Exceptional, (15 reviews)
"We have family in the area and stayed here for an evening Everything we needed was right there including a pizza in the freezer which was delicious! We enjoyed the fire pit complete with plenty of wood to burn The chickens were so fun to watch!! The farm house is adorable and to be able to snap a picture of the peaches beginning to ripen was so neat !"
United States
Dianne M.
The price is HK$1,478
HK$1,851 total
includes taxes & fees
13 Sept - 14 Sept
Rendelman Orchard's Farm Stay
A rustic cabin with a stone chimney, wooden deck, and a porch.

19. Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!

Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!
Makanda
9.6 out of 10, Exceptional, (50 reviews)
"We enjoyed our stay at the well outfitted cabin near the Shawnee Wine Trail. Cabin is conveniently located near Giant City State Park and the lodge restaurant. "
United States
Janine B.
The price is HK$855
HK$1,670 total
includes taxes & fees
14 Sept - 15 Sept
Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!
A wooden cabinet with a microwave, coffee maker, and plates.

20. Cozy and Updated Farmhouse with King Suite

Cozy and Updated Farmhouse with King Suite
Anna
10.0 out of 10, Exceptional, (22 reviews)
"Comfortable bed which is what we needed. We weren’t there long but is was everything we needed."
United States
Kathy H.
The price is HK$699
HK$1,239 total
includes taxes & fees
7 Sept - 8 Sept
Cozy and Updated Farmhouse with King Suite
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cape Girardeau County Hotel Reviews

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

10/10 Excellent
"Nice place! Breakfast was amazing!"
Rebecca 2-night trip
Posted 18 hours ago
Drury Inn & Suites Cape Girardeau