Hannibal Vacation Homes

A river with a bridge, a town, and a forested hillside.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

In two weeks

In two months

In three months

In four months

Our top choices for Hannibal holiday homes

A dining area with a wooden table and chairs, a chandelier, and a red sofa in the background.

1. Vibey home a few blocks from downtown Hannibal

Hannibal

Terry

HK$2,266 total

includes taxes & fees

18 Oct - 19 Oct

A room with a brick wall, shelves with plants, a framed painting, and a patterned bench.

2. Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi

Hannibal

Lisa B.

HK$1,470 total

includes taxes & fees

3 Nov - 4 Nov

A living room with a grey sofa, a white coffee table, and teal chairs. A kitchen is visible through an open door.

3. Modern and comfy home five minutes from downtown

Hannibal

Brent W.

HK$2,337 total

includes taxes & fees

19 Oct - 20 Oct

A cozy living room with a wooden staircase, a chessboard on a round table, and a lamp on a side table.

4. The John Sydney House - Family and Pet Friendly Historic Home Downtown

Hannibal

Brian H.

HK$2,015 total

includes taxes & fees

19 Oct - 20 Oct

A modern kitchen with white cabinets, a stainless steel refrigerator, and a dining area with a wooden table and white chairs.

5. Peaceful, Country Cottage with Open Floor Plan

Quincy

Anonymous traveller

HK$1,938 total

includes taxes & fees

22 Oct - 23 Oct

A modern kitchen with stainless steel appliances, a stone accent wall, and a bar area.

6. Aunt Lele's Cozy Cottage

Quincy

Matt B.

HK$1,230 total

includes taxes & fees

18 Oct - 19 Oct

A modern kitchen with white cabinets, stainless steel appliances, and a wooden floor.

7. Spacious & Modern 2BR Home with Attached Garage

Quincy

Marsha

HK$1,599 total

includes taxes & fees

19 Oct - 20 Oct

A modern kitchen with wooden cabinets, stainless steel appliances, and a large island with bar stools.

8. Shouse Near Mark Twain Lake!

Monroe City

Christina H.

HK$2,567 total

includes taxes & fees

29 Oct - 30 Oct

View all properties

Find holiday rentals that suit your style

Cabins

Apartments

Save an average of 15% on thousands of hotels when you're signed in

Top Hannibal Hotel Reviews

Best Western On The River

10/10 Excellent

"We arrived at 8:20 pm and were told that the hot tub and pool closed at 9:00 pm and didn’t open till 9:30 am . The other thing was the remote control for our TV wouldn’t let us use closed captioning ."

The John Sydney House - Family and Pet Friendly Historic Home Downtown

10/10 Excellent

"Host was very responsive. We accidentally left a suit behind after staying for a wedding and we were able to arrange to pick it up during to the fact the host was very quick to respond. Would recommend to anyone."

Jacuzzi Tub & Full Kitchen: Dowtown Hannibal Loft

10/10 Excellent

"This is a cute unit in the heart of it all on Main Street. Very nicely designed and maintained. I looked up the history of the property and found out it was a drug store built in the late 1800s and operated until 1986. Now converted into a bar and grill at street level and this fun unit on the third floor. Just lovely. Very safe and secure. Parking is close and was readily available. Two drawbacks for me was that I looked everywhere and found no hairdryer. I also felt the cleaning fee which was almost as much as the nightly rate was very high for folks that stay one night like we did. A sliding scale for cleaning fees would be a good idea. If the fee was the same for three nights as it was for one night, I would find that reasonable. It was just too high for one night. All in all it was a wonderful stay. I hope the owners take my comments are constructive versus a criticism. They’ve made a lovely space for visitors to a magical place. Thanks so much."

Garden House Bed and Breakfast....Cozy 1895 Queen Anne Victorian,

8/10 Good

"We really enjoyed our stay and especially loved the cat hostess. We are both cat lovers and are without cats at the moment so that was just sweet. We were disappointed to find that breakfast wasn’t served at the bed-and-breakfast and which was advertised on the in the listing, but our host said that it was a separate add-on, Chris, our host was very helpful when we accidentally left a bag behind and we had to drive over and pick it up from him. He was very gracious to meet us."

Find out more about Hannibal