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Hyannis Main Street Hyannis Hotels

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Check prices for these dates

Next weekend
7 Aug - 9 Aug
In two weeks
14 Aug - 16 Aug

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Our top choices for Main Street Hyannis hotels

Exterior

1. Heritage House Inn on Cape Cod, an Ascend Collection Hotel

Heritage House Inn on Cape Cod, an Ascend Collection Hotel
2.5 star property
0.3 km from Main Street Hyannis
9.0 out of 10, Wonderful, (79 reviews)
"Nice hotel in a great area"
Canada
Gary
The price is HK$1,247
HK$1,427 total
includes taxes & fees
31 Aug - 1 Sept
Heritage House Inn on Cape Cod, an Ascend Collection Hotel
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers

2. Hampton Inn & Suites Cape Cod-West Yarmouth

Hampton Inn & Suites Cape Cod-West Yarmouth
2.5 star property
1.7 km from Main Street Hyannis
8.8 out of 10, Excellent, (1,002 reviews)
"Clean room and fresh coffee , staff was friendly"
United States
margaret
The price is HK$2,327
HK$2,663 total
includes taxes & fees
18 Aug - 19 Aug
Hampton Inn & Suites Cape Cod-West Yarmouth
Exterior

3. Cape Sands Inn

Cape Sands Inn
2.5 star property
1.9 km from Main Street Hyannis
8.2 out of 10, Very good, (1,118 reviews)
"Great location"
United States
Cleison
The price is HK$773
HK$885 total
includes taxes & fees
31 Aug - 1 Sept
Cape Sands Inn
Free daily continental breakfast

4. Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod
2.5 star property
0.3 km from Main Street Hyannis
8.2 out of 10, Very good, (1,005 reviews)
"Great location and extremely friendly service!"
United States
Chandler
The price is HK$1,263
HK$1,446 total
includes taxes & fees
27 Aug - 28 Aug
Comfort Inn Hyannis - Cape Cod
Beach

5. Sunbird Cape Cod Resort

Sunbird Cape Cod Resort
2.5 star property
2.3 km from Main Street Hyannis
7.8 out of 10, Good, (602 reviews)
"Nice stay."
United States
Eliani
The price is HK$968
HK$1,108 total
includes taxes & fees
30 Aug - 31 Aug
Sunbird Cape Cod Resort
Beach

6. Sunbird ANNEX Resort

Sunbird ANNEX Resort
2.0 star property
2.3 km from Main Street Hyannis
7.8 out of 10, Good, (885 reviews)
"Rooms were clean and staff was super helpful. The breakfast was phenomenal"
United States
Nashaiyaa
The price is HK$1,060
HK$1,213 total
includes taxes & fees
30 Aug - 31 Aug
Sunbird ANNEX Resort
Lobby

7. Hyannis Plaza Hotel

Hyannis Plaza Hotel
2.5 star property
0.9 km from Main Street Hyannis
7.2 out of 10, Good, (1,010 reviews)
"Great hotel, room was clean and really nice"
United States
Jackeline
The price is HK$1,518
HK$1,816 total
includes taxes & fees
24 Aug - 25 Aug
Hyannis Plaza Hotel
Lobby

8. Days Inn by Wyndham West Yarmouth/Hyannis Cape Cod Area

Days Inn by Wyndham West Yarmouth/Hyannis Cape Cod Area
2.0 star property
1.5 km from Main Street Hyannis
7.0 out of 10, Good, (1,001 reviews)
"Clean comfortable and very good service. Great location"
United States
Jason
The price is HK$776
HK$889 total
includes taxes & fees
1 Sept - 2 Sept
Days Inn by Wyndham West Yarmouth/Hyannis Cape Cod Area
Iron/ironing board, free WiFi, bed sheets

9. Relax Inn Cape Cod

Relax Inn Cape Cod
2.0 star property
1.4 km from Main Street Hyannis
6.4 out of 10, (799 reviews)
"Clean room, quiet night, breakfast place across the street. Good stopover."
United States
Mark O.
The price is HK$844
HK$965 total
includes taxes & fees
31 Aug - 1 Sept
Relax Inn Cape Cod
Seasonal outdoor pool

10. Econo Lodge West Yarmouth on Cape Cod

Econo Lodge West Yarmouth on Cape Cod
2.5 star property
1.5 km from Main Street Hyannis
6.2 out of 10, (525 reviews)
"Property needs to be updated especially tubs."
United States
Lisa
The price is HK$933
HK$1,068 total
includes taxes & fees
1 Sept - 2 Sept
Econo Lodge West Yarmouth on Cape Cod
Exterior

11. Cape Cod Motor Inn

Cape Cod Motor Inn
3.5 star property
6 km from Main Street Hyannis
10.0 out of 10, Exceptional, (77 reviews)
"Everything about our stay was wonderful!"
United States
Jennifer
The price is HK$1,685
HK$1,928 total
includes taxes & fees
4 Aug - 5 Aug
Cape Cod Motor Inn
Terrace/patio

12. Sesuit Harbor House

Sesuit Harbor House
3.0 star property
13.9 km from Main Street Hyannis
9.6 out of 10, Exceptional, (200 reviews)
"Had a pleasant stay! Owner is very helpful!"
United States
sherry
The price is HK$2,370
HK$2,712 total
includes taxes & fees
31 Aug - 1 Sept
Sesuit Harbor House
Front of property – evening/night

13. The Inn At Cape Cod

The Inn At Cape Cod
4.0 star property
6.4 km from Main Street Hyannis
9.6 out of 10, Exceptional, (94 reviews)
"Amazing inn and the owners are great!"
United States
Harini
The price is HK$3,913
HK$4,479 total
includes taxes & fees
4 Aug - 5 Aug
The Inn At Cape Cod
Exterior

14. Dennis Port Surf Club (Boutique Hotel)

Dennis Port Surf Club (Boutique Hotel)
3.0 star property
12.4 km from Main Street Hyannis
9.6 out of 10, Exceptional, (23 reviews)
"Very cute Motel style Hotel- Clean and comfortable room. It is in a great location- easy to tourist around"
United States
Jose Alejandro
The price is HK$2,036
HK$2,330 total
includes taxes & fees
1 Sept - 2 Sept
Dennis Port Surf Club (Boutique Hotel)
Premium bedding, down duvets, iron/ironing board, free WiFi

15. Chatham Tides

Chatham Tides
2.5 star property
20.9 km from Main Street Hyannis
9.4 out of 10, Exceptional, (739 reviews)
"Lovely stay"
United States
Annie
The price is HK$3,141
HK$3,595 total
includes taxes & fees
1 Sept - 2 Sept
Chatham Tides
Front of property

16. Ambassador Inn & Suites

Ambassador Inn & Suites
3.0 star property
8.2 km from Main Street Hyannis
8.6 out of 10, Excellent, (714 reviews)
"The room was clean and staff very nice. The pool areas were fun for the family as well, especially on rainy days."
Canada
Claire
The price is HK$1,353
HK$1,615 total
includes taxes & fees
23 Aug - 24 Aug
Ambassador Inn & Suites
Free daily buffet breakfast

17. Holiday Inn Express Hyannis Cape Cod by IHG

Holiday Inn Express Hyannis Cape Cod by IHG
2.5 star property
4 km from Main Street Hyannis
8.8 out of 10, Excellent, (19 reviews)
"Great location excellent breakfast"
Canada
Diane
The price is HK$1,051
HK$1,203 total
includes taxes & fees
31 Aug - 1 Sept
Holiday Inn Express Hyannis Cape Cod by IHG
Indoor pool, outdoor pool, pool umbrellas, pool loungers

18. Margaritaville Resort Cape Cod

Margaritaville Resort Cape Cod
4.0 star property
3.3 km from Main Street Hyannis
8.6 out of 10, Excellent, (658 reviews)
"The staff was very friendly"
United States
Marzena
The price is HK$1,744
HK$2,445 total
includes taxes & fees
19 Aug - 20 Aug
Margaritaville Resort Cape Cod
Premium bedding, iron/ironing board, free WiFi, alarm clocks

19. Love Farms Lodge

Love Farms Lodge
2.5 star property
11 km from Main Street Hyannis
8.6 out of 10, Excellent, (410 reviews)
"Everything was beautifully kept and the property was so updated within the suite we had. It was perfect for our soccer weekend with the rain involved. Perfect family place."
United States
Aura
The price is HK$1,193
HK$1,474 total
includes taxes & fees
31 Aug - 1 Sept
Love Farms Lodge
Terrace/patio

20. The Corsair & Cross Rip Oceanfront Resort

The Corsair & Cross Rip Oceanfront Resort
2.5 star property
13.4 km from Main Street Hyannis
8.6 out of 10, Excellent, (290 reviews)
"Great staff, excellent location"
United States
Guzel
The price is HK$2,266
HK$2,661 total
includes taxes & fees
31 Aug - 1 Sept
The Corsair & Cross Rip Oceanfront Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Main Street Hyannis

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Exterior
Heritage House Inn on Cape Cod, an Ascend Collection Hotel
2.5 star property
9.0
Wonderful
79 reviews
View
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers
Hampton Inn & Suites Cape Cod-West Yarmouth
2.5 star property
8.8
Excellent
1,002 reviews
View
Exterior
Cape Sands Inn
2.5 star property
8.2
Very good
1,118 reviews
View
Free daily continental breakfast
Comfort Inn Hyannis - Cape Cod
2.5 star property
8.2
Very good
1,005 reviews
View
Beach
Sunbird Cape Cod Resort
2.5 star property
7.8
Good
602 reviews
View

Top Main Street Hyannis Hotel Reviews

Anchor In Distinctive Waterfront Lodging

Anchor In Distinctive Waterfront Lodging

10/10 Excellent
"It’s was great from check in to check out, it was walking distance to a lot of shops and restaurants. We will definitely stay there again."
Holly 4-night trip
Posted 3 hours ago
Anchor In Distinctive Waterfront Lodging

Other attractions near Main Street Hyannis

A bronze statue of a man in a polo shirt standing in front of a building with a brick facade, white columns, and an American flag.

John F. Kennedy Hyannis Museum

8.8/10 (444 reviews)
Learn about the 35th president of the United States at this revealing museum, which is just a short distance from the Kennedy Compound.
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Frequently asked questions

What's the area like around Main Street Hyannis?
Main Street Hyannis is located in a walkable area of Hyannis known for its top seafood restaurants and major shopping area. If you're looking for a convenient place to stay, take a look at the 200 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay near Main Street Hyannis?
Adjacent to Main Street Hyannis, Comfort Inn Hyannis - Cape Cod is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. Other good options within a short distance include Hyannis Harbor Hotel and Heritage House Inn on Cape Cod, an Ascend Collection Hotel.
How many hotels can I expect to find near Main Street Hyannis?
Expedia has 200 hotels and other accommodation options within a mile from Main Street Hyannis.
If I need to cancel the hotel reservation for my stay near Main Street Hyannis, will I receive a refund?
Yes! Most hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and get a refund within 24 hours of your booking. Add dates, click "Search", then filter by "fully refundable" to review the top deals on offer near Main Street Hyannis.
What can I see and do near Main Street Hyannis?
John F. Kennedy Hyannis Museum, Edward Gorey House and Cape Cod Maritime Museum feature captivating exhibits. Hyannis Harbor, St Mary's Episcopal Church and Sandy Neck Lighthouse are landmarks that you won't want to miss. Local parks like Lewis Bay, Veterans Memorial Park and Dennis Pond Conservation Area are peaceful spots to stop and take in some fresh air.