Hyannis Main Street Hyannis Hotels

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
29 Nov - 30 Nov
Tomorrow
30 Nov - 1 Dec
Next weekend
5 Dec - 7 Dec
In two weeks
12 Dec - 14 Dec

Filter by

Guest rating
Guest rating
Star rating

Top Trending Hotels Near Main Street Hyannis

Terrace/patio
Anchor In Distinctive Waterfront Lodging

Anchor In Distinctive Waterfront Lodging

3.0 star property
0.6 km from Main Street Hyannis
9.4 out of 10, Exceptional, (1005)
"Beautiful quaint hotel, with a nice view of the water. The place has a pool, a fire pit and nice spacious rooms. Would stay again. "
United States
Alberto
The price is HK$1,675
HK$2,318 total
includes taxes & fees
6 Dec - 7 Dec
Anchor In Distinctive Waterfront Lodging
View from room
Uncommoner Hotel by Reverie Boutique Collection

Uncommoner Hotel by Reverie Boutique Collection

3.0 star property
1.9 km from Main Street Hyannis
9.4 out of 10, Exceptional, (95)
"Great staff, beautiful property"
United States
Margaret
The price is HK$792
HK$907 total
includes taxes & fees
4 Dec - 5 Dec
Uncommoner Hotel by Reverie Boutique Collection
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers
Hampton Inn & Suites Cape Cod-West Yarmouth

Hampton Inn & Suites Cape Cod-West Yarmouth

2.5 star property
1.7 km from Main Street Hyannis
8.8 out of 10, Excellent, (1006)
"Excellent stay."
United States
Patricia
The price is HK$865
HK$990 total
includes taxes & fees
7 Dec - 8 Dec
Hampton Inn & Suites Cape Cod-West Yarmouth
View from property
Courtyard By Marriott Cape Cod Hyannis

Courtyard By Marriott Cape Cod Hyannis

3.0 star property
1.7 km from Main Street Hyannis
8.8 out of 10, Excellent, (484)
"Pretty nice location"
United States
Saulius
The price is HK$846
HK$969 total
includes taxes & fees
14 Dec - 15 Dec
Courtyard By Marriott Cape Cod Hyannis
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers
Bayside Resort Hotel

Bayside Resort Hotel

3.0 star property
2.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (1529)
"Great place..Friday wonderful breakfast, clean as always. Have stayed here 6 timmes Never disappointed "
United States
Donna
The price is HK$577
HK$750 total
includes taxes & fees
17 Dec - 18 Dec
Bayside Resort Hotel
Lobby lounge
Fairfield Inn & Suites by Marriott Cape Cod Hyannis

Fairfield Inn & Suites by Marriott Cape Cod Hyannis

2.5 star property
2.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (647)
"Great people, nice breakfast "
United States
Lorri
The price is HK$832
HK$953 total
includes taxes & fees
7 Dec - 8 Dec
Fairfield Inn & Suites by Marriott Cape Cod Hyannis
Exterior
Doubletree by Hilton Cape Cod - Hyannis

Doubletree by Hilton Cape Cod - Hyannis

4.0 star property
1 km from Main Street Hyannis
8.4 out of 10, Very good, (874)
"Great location, awesome area for amenities, delicious cookies, as usual!"
United States
John
The price is HK$860
HK$984 total
includes taxes & fees
19 Dec - 20 Dec
Doubletree by Hilton Cape Cod - Hyannis
Free daily continental breakfast
Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod

2.5 star property
0.3 km from Main Street Hyannis
8.0 out of 10, Very good, (1002)
"Karla at the front desk was so welcoming and accommodating."
United States
Megan
The price is HK$763
HK$873 total
includes taxes & fees
7 Dec - 8 Dec
Comfort Inn Hyannis - Cape Cod
Indoor pool
Courtyard Resort

Courtyard Resort

2.0 star property
0.3 km from Main Street Hyannis
8.0 out of 10, Very good, (38)
"Staff extremely helpful, pleasant. Rooms clean, pool terrific. "
United States
katherine
The price is HK$848
HK$970 total
includes taxes & fees
30 Nov - 1 Dec
Courtyard Resort
Front of property
Hyannis Harbor Hotel

Hyannis Harbor Hotel

3.5 star property
0.6 km from Main Street Hyannis
8.0 out of 10, Very good, (1008)
"Very clean, staff friendly and all amenities were great!"
United States
Joao
The price is HK$914
HK$1,361 total
includes taxes & fees
30 Nov - 1 Dec
Hyannis Harbor Hotel
Exterior
Cape Sands Inn

Cape Sands Inn

2.5 star property
1.9 km from Main Street Hyannis
8.2 out of 10, Very good, (1015)
"I love this hotel clean good up keep "
United States
Jerome
The price is HK$557
HK$637 total
includes taxes & fees
30 Nov - 1 Dec
Cape Sands Inn
Exterior
Holiday Inn Hyannis by IHG

Holiday Inn Hyannis by IHG

3.0 star property
2.9 km from Main Street Hyannis
8.2 out of 10, Very good, (973)
"Great place to stay "
United States
Lilian
The price is HK$887
HK$1,015 total
includes taxes & fees
8 Dec - 9 Dec
Holiday Inn Hyannis by IHG
Lobby
Hyannis Plaza Hotel

Hyannis Plaza Hotel

2.5 star property
0.9 km from Main Street Hyannis
7.0 out of 10, Good, (962)
"Great place "
United States
mirza
The price is HK$595
HK$759 total
includes taxes & fees
29 Dec - 30 Dec
Hyannis Plaza Hotel
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers
Cape Cod Irish Village

Cape Cod Irish Village

3.5 star property
1.4 km from Main Street Hyannis
6.4 out of 10, (1002)
"Plenty of parking space, walking distance to shops & restaurants."
United States
FLOR
The price is HK$916
HK$1,049 total
includes taxes & fees
30 Nov - 1 Dec
Cape Cod Irish Village
Seasonal outdoor pool
Econo Lodge by Choice - Cape Cod

Econo Lodge by Choice - Cape Cod

2.5 star property
1.5 km from Main Street Hyannis
6.2 out of 10, (508)
"Great place to stay close to everything "
United States
Markeith
The price is HK$653
HK$748 total
includes taxes & fees
30 Nov - 1 Dec
Econo Lodge by Choice - Cape Cod
Shared kitchen
Sal's Place

Sal's Place

2.0 star property
2.5 km from Main Street Hyannis
The price is HK$2,178
HK$3,426 total
includes taxes & fees
1 Dec - 2 Dec
Sal's Place
Garden
The Village Inn Cape Cod

The Village Inn Cape Cod

3.5 star property
6.1 km from Main Street Hyannis
10.0 out of 10, Exceptional, (222)
"It was so charming, would definitely stay there again! "
United States
Kyle
The price is HK$1,315
HK$1,505 total
includes taxes & fees
8 Dec - 9 Dec
The Village Inn Cape Cod
Outdoor pool, pool umbrellas, pool loungers
Margaritaville Resort Cape Cod

Margaritaville Resort Cape Cod

4.0 star property
3.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (408)
"Very nice place to stay "
United States
James
The price is HK$920
HK$1,498 total
includes taxes & fees
30 Nov - 1 Dec
Margaritaville Resort Cape Cod
Property grounds
The Escape Inn

The Escape Inn

2.5 star property
7.6 km from Main Street Hyannis
9.4 out of 10, Exceptional, (650)
"One of the best hotels I stayed at "
United States
Robert
The price is HK$698
HK$799 total
includes taxes & fees
30 Nov - 1 Dec
The Escape Inn
Exterior
Aiden by Best Western Cape Cod - West Yarmouth

Aiden by Best Western Cape Cod - West Yarmouth

3.0 star property
3.7 km from Main Street Hyannis
8.0 out of 10, Very good, (1007)
"Nice place and good options for breakfast "
United States
Jennifer
The price is HK$754
HK$863 total
includes taxes & fees
7 Dec - 8 Dec
Aiden by Best Western Cape Cod - West Yarmouth
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Main Street Hyannis Hotel Reviews

Hampton Inn & Suites Cape Cod-West Yarmouth

Hampton Inn & Suites Cape Cod-West Yarmouth

10/10 Excellent
"Immaculate hotel, beautiful decorations, high end front desk service in check in. Manager was very personable and accommodating. "
Denis 1-night trip
Posted 3 days ago
Hampton Inn & Suites Cape Cod-West Yarmouth

Hotels near other Main Street Hyannis attractions

John F. Kennedy Hyannis Museum showcases bronze statue and historic architecture in Hyannis Massachusetts

John F. Kennedy Hyannis Museum

4.4/5 (259 reviews)
Learn about the 35th president of the United States at this revealing museum, which is just a short distance from the Kennedy Compound.
See properties
Cape Cod Maritime Museum which includes a bay or harbor and signage

Cape Cod Maritime Museum

You can spend an afternoon studying the exhibits at Cape Cod Maritime Museum during your trip to Hyannis. Stroll along the seaside in this family-friendly area or visit its seafood restaurants.
See properties

Frequently asked questions

What's the area like around Main Street Hyannis?
Main Street Hyannis is located in a walkable area of Hyannis known for its top seafood restaurants and major shopping area. If you're looking for a convenient place to stay, take a look at the 180 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay near Main Street Hyannis?
Adjacent to Main Street Hyannis, Hyannis Travel Inn is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an outdoor pool. Other good options within a short distance include Courtyard Resort and Comfort Inn Hyannis - Cape Cod.
How many hotels can I expect to find near Main Street Hyannis?
Expedia has 180 hotels and other accommodation options within a mile from Main Street Hyannis.
If I need to cancel the hotel reservation for my stay near Main Street Hyannis, will I receive a refund?
Yes! Most hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and get a refund within 24 hours of your booking. Add dates, click "Search", then filter by "fully refundable" to review the top deals on offer near Main Street Hyannis.
What can I see and do near Main Street Hyannis?
John F. Kennedy Hyannis Museum, Whydah Pirate Museum and Cape Cod Maritime Museum feature captivating exhibits. Hyannis Harbor, Edward Gorey House and Sandy Neck Lighthouse are landmarks that you won't want to miss. You can enjoy live performances at Cape Cod Melody Tent and Barnstable Performing Arts Center.

Explore a world of travel with Expedia