Name: Megapolis Hotel Panamá
Price range: HK$1,254

Stay near popular Santa Ana attractions

El Machetazo Santa Ana

You can browse for the perfect souvenirs at El Machetazo Santa Ana during your visit to Panama City. Amble around the area's parks or visit its shops.

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Top hotels in Santa Ana

Hotel Caracas - Casco Viejo

Plaza De Santa Ana Panama City Provincia di Panama

HK$403

HK$443 total

20 Oct - 21 Oct

includes taxes & fees

Stay at this hotel in Panama City. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour front desk. Popular attractions Albrook Shopping Mall and Cinta Costera ...

8/10 Very good! (20 reviews)

"Good location but basic otherwise. Staff not overly helpful on the whole."

Reviewed on 27 Sept 2026

Casco View Life Residences

C. 16 Oeste Panama City Provincia de Panamá

HK$657

HK$958 total

20 Oct - 21 Oct

includes taxes & fees

Stay at this business-friendly condo in Panama City. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour front desk. Popular attractions Albrook Shopping Mall ...

Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama

Fully refundableReserve now, pay when you stay

HK$1,110

HK$1,221 total

25 Oct - 26 Oct

includes taxes & fees

Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and 3 restaurants. Our guests praise the breakfast and the pool in their reviews. ...

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Via Espana 111 Panama City Panama

HK$749

HK$824 total

8 Nov - 9 Nov

includes taxes & fees

Stay at this spa hotel in Panama City. Enjoy free breakfast, free parking and a full-service spa. Our guests praise the helpful staff in their reviews. Popular ...

7.8/10 Good! (1,001 reviews)

"Our room was giant and dated with little furniture and extras. Tea and coffee was a one time deal. We often had to ask for water and towels otherwise they wouldn’t be stocked. The reception was slow to respond and at times did not help with basics. ( Water was lukewarm most days with the exception ..."

Reviewed on 17 Oct 2026

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz Tocumen Panama

HK$957

HK$1,105 total

5 Nov - 6 Nov

includes taxes & fees

Stay at this family-friendly hotel in Tocumen. Enjoy free Wi-Fi, breakfast (surcharge) and a free airport shuttle. Our guests praise the breakfast and the pool ...

Megapolis Hotel Panamá

Avenida Balboa Panama City

HK$1,254

HK$1,379 total

31 Oct - 1 Nov

includes taxes & fees

Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their reviews. ...

See all 1,788 properties in Santa Ana

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

A coastal cityscape with a prominent church tower, a river, and distant mountains.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

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A modern, spiraling skyscraper with a unique design, surrounded by other buildings in an urban setting.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

A city skyline with modern high-rise buildings and a river in the foreground.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.