Santa Ana

Panama City

Photo by Isa
Photo by Isa

Popular places to visit

Multiplaza Pacific Mall

Multiplaza Pacific Mall

4.5/5(8 reviews)

During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Multiplaza Pacific Mall
Cinta Costera

Cinta Costera

4/5(5 reviews)

Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.

Cinta Costera
Avenida Balboa

Avenida Balboa

3.5/5(9 reviews)

You can browse for the perfect souvenirs at Avenida Balboa during your stay in Panama City. While you're in the area, wander around the natural setting.

Avenida Balboa
Fuerte Amador Resort & Marina

Fuerte Amador Resort & Marina

Explore the waterfront in Ancon with a trip to Fuerte Amador Resort & Marina. Visit the shops and top-notch restaurants in this vibrant area.

Fuerte Amador Resort & Marina
Panama

Miraflores Locks

4.5/5(12 reviews)

Learn about the local history of Ancon when you spend time at Miraflores Locks. Visit the shops and casinos in this vibrant area.

Miraflores Locks
Calle 50

Calle 50

You can find out about the history of Panama City when you stop by Calle 50. Discover the area's shops or seek out its local tours.

Calle 50

Things to do

Slingshot Tour Panama

Slingshot Tour Panama

HK$921
per adult
Slingshot Tour Panama
Cinta Costera

Half day of Panama city and canal tour: shared and private

HK$523
per adult
98% of travellers recommend
Half day of Panama city and canal tour: shared and private
Day Tour

Day Tour in San Blas Islands All Included Visiting 4 Islands

HK$1,170
per adult
94% of travellers recommend
Day Tour in San Blas Islands All Included Visiting 4 Islands
Panama Hop-On Hop-Off Bus Tour

City Sightseeing Panama City Hop-On Hop-Off Bus Tour

HK$235
per adult
80% of travellers recommend
City Sightseeing Panama City Hop-On Hop-Off Bus Tour
Panama City: All-Inclusive Catamaran Cruise to Taboga Island

Panama City: All-Inclusive Catamaran Cruise to Taboga Island

HK$777
per adult
94% of travellers recommend
Panama City: All-Inclusive Catamaran Cruise to Taboga Island
Panama City: Poin Glass Observation Deck Ticket with VR Tour

Panama City: Poin Glass Observation Deck Ticket with VR Tour

HK$252
per adult
100% of travellers recommend
Panama City: Poin Glass Observation Deck Ticket with VR Tour
See all activities in Panama City

Top hotels in Santa Ana

Casco View Apartments
Casco View Apartments
3 out of 5
C. 16 Oeste, Panama City, Provincia de Panamá
Stay at this 3-star condo in Panama City. Enjoy free WiFi, premium bedding, and in-room washers/dryers. Popular attractions Albrook Shopping Mall and Cinta Costera ...
9.4/10 Exceptional! (38 reviews)
"I liked the buildings quietness and modern style."

Reviewed on 23 Jun 2025

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Casco View Apartments
Hotel Riu Plaza Panama
Hotel Riu Plaza Panama
5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
The price is HK$934 per night from 13 Jul to 14 Jul
HK$934
HK$1,028 total
13 Jul - 14 Jul
includes taxes & fees
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (4,083 reviews)
"THE CENTER OF CITY, CLOSE TO NUMBER OF ACTIVITIES. WEEKDAY VERY CONGESTED ROADS."

Reviewed on 10 Jul 2025

Hotel Riu Plaza Panama
Dreams Playa Bonita Panama - All Inclusive
Dreams Playa Bonita Panama - All Inclusive
4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
The price is HK$1,923 per night from 1 Aug to 2 Aug
HK$1,923
HK$1,923 total
1 Aug - 2 Aug
includes taxes & fees
Stay at this 4-star beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...
7.2/10 Good! (1,001 reviews)
"We had a wonderful stay at Dreams Playa Bonita. The staff is very welcoming and hospitable. The room was clean and with a beautiful beach view. We loved that they had breakfast, lunch, and dinner all included. They also have coffee and snack shops open throughout the day! To us, this has been the ..."

Reviewed on 5 Jul 2025

Dreams Playa Bonita Panama - All Inclusive
Sheraton Grand Panama
Sheraton Grand Panama
4 out of 5
Via Israel And 77th Street, Panama City, Panama
The price is HK$911 per night from 18 Jul to 19 Jul
HK$911
HK$1,003 total
18 Jul - 19 Jul
includes taxes & fees
Stay at this 4-star spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.4/10 Very Good! (891 reviews)
"a clean and nice hotel , Lobby area was very nice with some nice shopping places, the rooms need a little update especially the bathroom, the service was excellent friendly and courteous"

Reviewed on 8 Jul 2025

Sheraton Grand Panama
Crowne Plaza Panama Airport by IHG
Crowne Plaza Panama Airport by IHG
4 out of 5
Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
The price is HK$873 per night from 12 Jul to 13 Jul
HK$873
HK$960 total
12 Jul - 13 Jul
includes taxes & fees
Stay at this 4-star family-friendly hotel in Tocumen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast and ...
8.4/10 Very Good! (2,141 reviews)
"Not bad for a stop through"

Reviewed on 7 Jul 2025

Crowne Plaza Panama Airport by IHG
Waymore Hotel Spa & Casino
Waymore Hotel Spa & Casino
4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi, Panama City
The price is HK$604 per night from 20 Jul to 21 Jul
HK$604
HK$664 total
20 Jul - 21 Jul
includes taxes & fees
Stay at this 4-star spa B&B in Panama City. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Albrook Shopping Mall and Via Espana are located ...
9/10 Wonderful! (330 reviews)
"This place was awesome"

Reviewed on 9 Jul 2025

Waymore Hotel Spa & Casino
See all 1,462 properties in Santa Ana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Santa Ana

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Casco Viejo

3.5/5(3 area reviews)

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Metropolitan Cathedral of Panama or Interoceanic Canal Museum while you're exploring the area.

Casco Viejo
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San Felipe

While visiting San Felipe, you might make a stop by sights like Metropolitan Cathedral of Panama and Interoceanic Canal Museum.

San Felipe
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El Chorrillo

While El Chorrillo isn't home to many top sights, Albrook Shopping Mall and Metropolitan Cathedral of Panama are some notable places to visit nearby.

El Chorrillo
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Calidonia

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Cinta Costera.

Calidonia
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Balboa

The restaurants and shopping are just a few features travellers like about Balboa. If you want to do some sightseeing nearby, Albrook Shopping Mall and Bridge of the Americas are a few top places to visit.

Balboa
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Marbella

You'll enjoy the restaurants and parks in Marbella. You might want to make time for a stop at Avenida Balboa or Cinta Costera.

Marbella

Santa Ana