Calle 50
Visit Calle 50
Tours & day trips
See all 355 activities
City Sightseeing Panama City Hop-On Hop-Off Bus Tour
Private & custom tours
See all 136 activities
Jungle quad bike Waterfall and Zipline Adventure from Panama City
Cruises & boat tours
See all 47 activities
All-inclusive Sunset Panama Bay Catamaran Tour From Panama City
Classes & workshops
See all 12 activities
Learn about Panama cocoa and create your own chocolate bar
Air, helicopter & balloon tours
See all 6 activities
Charter Flights Panama City
Popular places to visit
Soho City Center
You can enjoy retail therapy at Soho City Center during your trip to Panama City. Discover the area's casinos or seek out its local tours.
Multiplaza Pacific Mall
During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
Avenida Balboa
You can browse for the perfect souvenirs at Avenida Balboa during your stay in Panama City. While you're in the area, wander around the natural setting.
Uruguay Street
During your visit to Panama City, you can search for that perfect souvenir at Uruguay Street. While in this family-friendly area, you can savour the top-notch restaurants.
Bingo 90
Why not roll the dice with a visit to Bingo 90 during your travels in Panama City? Visit the casinos and shops in this vibrant area.
National Shrine of the Heart of Mary
You can learn about the history of Panama City with a trip to National Shrine of the Heart of Mary. Stroll along the seaside or visit the casinos in this vibrant area.
Top Calle 50 Hotel Deals
Hotel Riu Plaza Panama
Megapolis Hotel Panamá
Principe Hotel and Suites
Decapolis Hotel Panama City
Novotel Panama City
Hospedium Princess Hotel Panama
Las Americas Golden Tower Panama
The Executive Hotel
JW Marriott Panama
Explore a world of travel with Expedia
Explore a world of travel with Expedia
- Holidays and getaways similar to Calle 50
- Hotels Near Calle 50
- Hotels near other Attractions
- Calle 50 Theme Hotels
- The Executive Hotel
- JW Marriott Panama
- Ramada Plaza By Wyndham Panama Punta Pacífica
- Courtyard by Marriott Panama Multiplaza Mall
- AC Hotel by Marriott Panama City
- Studio Coliving
- Plaza Paitilla Inn Hotel
- Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
- Holiday Inn Panama Distrito Financiero by IHG
- Waldorf Astoria Panama
- Hyatt Regency Panama City
- W Panama