Best Santa Isabel Hotels in 2026 from HK$308 - Fully Refundable Options

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Our top choices for Santa Isabel hotels

A modern kitchen with a large island, bar stools, pendant lighting, and a staircase leading to an upper level.

A modern living room with a sofa, coffee table, and shelves with decorative items.

A modern kitchen with a bar area, wooden chairs, pendant lighting, and a large flat-screen TV.

A swimming pool with two umbrellas, lounge chairs, and potted plants.

1. Fairfield Inn & Suites by Marriott Mexicali

Mexicali

LEONEL

HK$894

HK$1,010 total

includes taxes & fees

11 Oct - 12 Oct

A bar area with seating, a bar counter, and a wall-mounted screen.

A hotel pool area with lounge chairs, palm trees, and a clear blue sky.

A modern hotel room with a large bed, a wooden headboard, a flat-screen TV, and a painting on the wall.

2. Hotel Araiza Mexicali

Mexicali

Monique

HK$877

HK$991 total

includes taxes & fees

30 Sept - 1 Oct

A modern lounge area with sofas, round tables, and pendant lighting.

A modern office space with a large table, chairs, and a bookshelf.

A modern bar area with a pool table, bar stools, and a burger on the counter.

A spacious indoor area with a central seating area, a reception desk, and a large window providing natural light.

3. City Express Plus by Marriott Mexicali

Mexicali

MANUEL

HK$702

HK$793 total

includes taxes & fees

4 Oct - 5 Oct

A modern outdoor seating area with wicker furniture, potted plants, and a wooden deck.

A hotel room with two beds, a sofa, a desk, and a bathroom visible through an open door.

A modern kitchen with a central island, bar stools, wooden cabinets, stainless steel appliances, and pendant lighting.

A modern living room with a sofa, armchairs, a coffee table, and a decorative wall piece.

4. Holiday Inn Express & Suites Mexicali by IHG

Mexicali

Mark

HK$982

HK$1,110 total

includes taxes & fees

16 Oct - 17 Oct

A breakfast table set with plates of food, glasses of orange juice, and a basket of pastries.

A laptop on a desk with a cup, a lamp, and a chair, overlooking a hilly landscape.

A pool area with lounge chairs and a covered seating area.

A person sitting on a bed with a glass of orange juice, a plate of fruit, and a magazine.

5. Fiesta Inn Mexicali

Civic Center

HK$659

HK$744 total

includes taxes & fees

4 Oct - 5 Oct

A hand holding a blue drink with ice cubes, a swimming pool, palm trees, and a hotel building in the background.

An indoor area with wicker furniture, a stone planter with rocks, and a bar area with a counter.

A bar area with wicker chairs, a counter, and a TV screen.

An outdoor patio area with tables and chairs, surrounded by palm trees and potted plants.

6. Hotel Lucerna Mexicali

Mexicali

Joanne

HK$817

HK$923 total

includes taxes & fees

13 Oct - 14 Oct

A rooftop lounge area with outdoor seating, large windows, and a view of the cityscape.

A hotel room with two beds, a desk, a chair, and a large window with curtains.

A modern lounge area with wicker furniture, a round coffee table, and potted plants.

A modern hotel with a large sign reading "COURTYARD BY MARRIOTT". It features a clean, rectangular facade with evenly spaced windows and a flat roof.

7. Courtyard by Marriott Mexicali

Mexicali

Cecilia

HK$1,020

HK$1,152 total

includes taxes & fees

11 Oct - 12 Oct

A buffet area with various food items and a counter.

A multi-story building with balconies, a parking area, and palm trees.

A gym with treadmills, weight machines, and dumbbells.

A hotel room with two beds, each with white linens and pillows, a wooden headboard, a nightstand with a phone and a small table, and a framed picture on the wall.

8. Calafia Hotel

Mexicali

Heriberto

HK$641

HK$724 total

includes taxes & fees

30 Sept - 1 Oct

A modern hotel lobby with a reception desk, a seating area with a sofa and coffee table, and artwork on the walls.

A multi-story hotel with a prominent sign, a flat roof, and a well-lit entrance.

A buffet setup with various food items and serving utensils.

A gym with treadmills, a mirrored wall, and a cityscape painting.

9. Sleep Inn Mexicali

Mexicali

Claudiu

HK$538

HK$651 total

includes taxes & fees

5 Oct - 6 Oct

A buffet area with various food dispensers, a coffee machine, and a salad bar.

A modern lounge area with a grey sofa, yellow ottoman, and a wooden coffee table. There are bar stools and a flat-screen TV mounted on a wooden wall.

A hotel reception area with two reception desks, a large painting on the wall, and a mezzanine level.

A hotel room with a bed, desk, chair, and a TV on the wall.

10. City Express by Marriott Mexicali

Mexicali

Paulina

HK$583

HK$658 total

includes taxes & fees

21 Oct - 22 Oct

A modern hotel lobby with a green and orange color scheme, multiple seating areas, and digital kiosks displaying hotel information.

A modern cafeteria with white tables and chairs, a blue wall with a sign, and pendant lighting.

A reception area with a blue wall, a wooden reception desk, a digital screen, and a refrigerator.

A modern hotel with a prominent 'one' sign, a stone facade, and a parking area with vehicles.

11. One Mexicali

Mexicali

Daniel

HK$518

HK$585 total

includes taxes & fees

2 Oct - 3 Oct

A pool area with lounge chairs, a covered seating area, and palm trees.

A spacious restaurant with multiple tables and chairs, a bar area with a marble countertop, and a view of the outside through large windows.

A hotel lobby with a reception desk, a large chandelier, and a modern design.

A courtyard with a pathway, palm trees, and a building with multiple windows.

12. Hotel Colonial Mexicali

Civic Center

Juan Ramon

HK$659

HK$745 total

includes taxes & fees

30 Sept - 1 Oct

A courtyard with a central fountain, a building with a balcony, and a tree.

A building with a green awning labeled "Chab's Restaurant" and a sign for "Siesta Real Hotel" above it.

Two people toasting with drinks at a table with a view of greenery outside.

A courtyard with a central fountain, surrounded by a building with balconies and a car parked nearby.

13. Hotel Siesta Real

Mexicali

Rogelio

HK$636

HK$719 total

includes taxes & fees

30 Sept - 1 Oct

A hotel room with a bed, a desk, a chair, a TV, and artwork on the walls.

A swimming pool with clear blue water, surrounded by palm trees and a stone wall.

A gym with treadmills, stationary bikes, and elliptical machines.

A reception desk with a wooden finish and a marble base, a neon sign above, and a snack display to the right.

14. Holiday Inn Mexicali Centro Civico by IHG

Civic Center

Hector

HK$806

HK$976 total

includes taxes & fees

3 Oct - 4 Oct

A hotel with multiple floors, a restaurant, and a parking area.

A lobby with a glass door, a staircase, and a Christmas tree.

A hotel room with a ceiling fan, an air conditioning unit, a mirror, and a wooden cabinet.

A hotel room with a bed, bedside tables, a ceiling fan, a TV, a wardrobe, and a mirror.

15. Hotel del Norte

Mexicali Historic Center

Hidalgo

HK$391

HK$505 total

includes taxes & fees

30 Sept - 1 Oct

A modern dining area with a sofa, tables, and chairs.

A hotel room with two beds, a TV, a desk, and a window with a city view.

A modern interior with seating areas, a bar, and a view of the outside.

A modern lobby with a reception desk, seating area, vending machine, and a flat-screen TV.

16. City Express Junior by Marriott Mexicali

Mexicali

RICARDO

HK$448

HK$506 total

includes taxes & fees

18 Oct - 19 Oct

A refrigerated display case with various dairy products and beverages.

A compact kitchen with a white refrigerator, wooden cabinets, a built-in microwave, and a window with a view.

A conference room with a long table, six chairs, and three pendant lights.

A multi-story hotel with a central entrance, multiple balconies, and a parking area with handicapped accessibility.

17. Extended Suites Mexicali Cataviña

Mexicali

Alisson

HK$413

HK$500 total

includes taxes & fees

13 Oct - 14 Oct

A reception area with a counter, a blue wall, a potted plant, and a window with a view.

A hotel reception area with a blue wall, a reception desk, a small counter, a window with a view of buildings, and a display of pastries.

A hotel with a modern design, featuring a prominent entrance, a parking area, and a sign indicating amenities.

A bedroom with a bed, white nightstands, a red accent on the nightstands, a wall with a motivational quote, and a brown bedspread.

18. Hotel Boulevard Mexicali

Mexicali

Carmen

HK$335

HK$379 total

includes taxes & fees

30 Sept - 1 Oct

A restaurant with booths and tables, a kitchen in the background, and a ceiling fan.

A parking lot with cars, a building with a red roof, and a palm tree.

A hotel reception area with a modern design, including a reception desk, wall clocks, and a sign for a new laundry service.

A hotel room with a bed, a desk with a mirror, a television, and a door labeled '103'.

19. Azteca de Oro Mexicali

Mexicali

Jaleah

HK$276

HK$312 total

includes taxes & fees

30 Sept - 1 Oct

A hotel with a sign reading "Cosmos Hotel" and a price tag of $795.

A spacious hallway with a chandelier, a fireplace, and a staircase.

A hotel room with two beds, a wooden cabinet, a television, and a door.

A staircase with a wooden handrail, a ceiling fan, and a door with a black gate.

20. Hotel Cosmos Don Carlos

Mexicali

Saul

HK$368

HK$415 total

includes taxes & fees

30 Sept - 1 Oct

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Top Santa Isabel Hotel Reviews

Fairfield Inn & Suites by Marriott Mexicali

10/10 Excellent

"Beautiful Hotel, friendly staff, delicious breakfast and excellent parking."

City Express by Marriott Mexicali

10/10 Excellent

"My whole experience at this hotel was excellent! Everything functioned properly and the breakfast was always fresh and available. I will definitely revisit this hotel in the future!"

Sleep Inn Mexicali

10/10 Excellent

"Great staff!"

One Mexicali

8/10 Good

"Está bien y tiene un Oxxo al lado."

Calafia Hotel

10/10 Excellent

"Clean Room"

City Express Plus by Marriott Mexicali

10/10 Excellent

"Una hermosa propiedad nos encantó mucho, la estadía, la tranquilidad y la atención del personal, soy housekeeping de la compañía de Marriot Shadow Ridge en California, me encantó mucho la estadía volveremos pronto. Gracias"

Fiesta Inn Mexicali

10/10 Excellent

"Todo muy bien"

Holiday Inn Mexicali Centro Civico by IHG

10/10 Excellent

"Exelente mente súper bien en todos los aspectos. Limpieza y atención 10/10"

Azteca de Oro Mexicali

10/10 Excellent

"Muy buena ubicacion, ala vuelta de el boulevard central de mexicali, habitaciones comodas, buen espacio, agua caliente y helada, desayuno incluido gratis, estacionamiento amplio"

More cheap stays in Santa Isabel

Motel Las Fuentes

Blvd Lopez Mateos 1655 Mexicali BC

HK$300

HK$369 total

30 Sept - 1 Oct

includes taxes & fees

Hotel Misión Plaza Mexicali

366 Av. Francisco I. Madero Mexicali BC

Get rates

7.2/10 Good! (54 reviews)

HOTEL DON QUIJOTE

Calz Independencia Independencia Mexicali BC

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Motel Kiss

Carretera a Aeropuerto 4300 Mexicali BC

Get rates

7.8/10 Good! (179 reviews)

Motel Las Dunas

Calle Rio Culiacan s/n, Compuertas Mexicali BC

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7.6/10 Good! (38 reviews)

Casa Movil tipo estudio

Sierra Sta Clara Sur Lomas de Abasolo Mexicali BC

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Frequently asked questions

What's the best place for a stay in Santa Isabel?

Hotel Araiza Mexicali, located 7 mi (11.3 km) from the heart of Santa Isabel, is a top choice for your stay, based on our traveller data. Other good choices for your stay in the area are Hotel Lucerna Mexicali and Extended Suites Mexicali Cataviña. See all available top hotels, or vacation rentals in Santa Isabel.

What are some of the best holiday rentals that Santa Isabel has to offer?

Casa Madeira: This holiday home rental outside of Santa Isabel is equipped with a BBQ, air conditioning and laundry facilities to help you feel comfortable during your stay. Kitchen amenities include a fridge, an oven and a microwave. See all vacation rentals in Santa Isabel.

If I need to cancel my hotel reservation in Santa Isabel, will I receive a refund?

Yes! You'll find that most hotel room reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Isabel.

What is staying in Santa Isabel like?

Visitors to Santa Isabel will definitely find plenty to explore and enjoy. There are 73 hotels and other accommodation options in the surrounding area. Find out more about Santa Isabel.

What is there to see in Santa Isabel?

Places to visit in the wider area include Mexicali Border Port I, City Forest and Zoo and Plaza Comercial La Cachanilla. You'll also find Eagles Nest Stadium and Plaza San Pedro in the area. Take a look at what more there is to see and do in Expedia's Santa Isabel guide.

What's the seasonal weather like in Santa Isabel?

The hottest months are usually July and August, with an average temperature of 34°C, while the coldest months are December and January, with an average of 16°C. Average annual precipitation for Santa Isabel is 84 mm.

Santa Isabel hotels from HK$308

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Santa Isabel

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Santa Isabel hotels

1. Fairfield Inn & Suites by Marriott Mexicali

2. Hotel Araiza Mexicali

3. City Express Plus by Marriott Mexicali

4. Holiday Inn Express & Suites Mexicali by IHG

5. Fiesta Inn Mexicali

6. Hotel Lucerna Mexicali

7. Courtyard by Marriott Mexicali

8. Calafia Hotel

9. Sleep Inn Mexicali

10. City Express by Marriott Mexicali

11. One Mexicali

12. Hotel Colonial Mexicali

13. Hotel Siesta Real

14. Holiday Inn Mexicali Centro Civico by IHG

15. Hotel del Norte

16. City Express Junior by Marriott Mexicali

17. Extended Suites Mexicali Cataviña

18. Hotel Boulevard Mexicali

19. Azteca de Oro Mexicali

20. Hotel Cosmos Don Carlos

Top Santa Isabel Hotel Reviews

Fairfield Inn & Suites by Marriott Mexicali

City Express by Marriott Mexicali

Sleep Inn Mexicali

One Mexicali

Calafia Hotel

City Express Plus by Marriott Mexicali

Fiesta Inn Mexicali

Holiday Inn Mexicali Centro Civico by IHG

Azteca de Oro Mexicali

More cheap stays in Santa Isabel

Motel Las Fuentes

Hotel Misión Plaza Mexicali

HOTEL DON QUIJOTE

Motel Kiss

Motel Las Dunas

Casa Movil tipo estudio

Frequently asked questions

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